Calculated based on number of publications stored in Pure and citations from Scopus
1992 …2021

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Dr. Jong Yun's work focuses on the development of sphingosine kinase (SphK) inhibitors as anti-cancer therapeutic agents.

The Yun research group is currently pursuing three separate projects that are centered around the development of therapeutic agents that specifically target SphK.

The first project, target identification, combines biochemistry and cell and molecular biology techniques to determine the signaling mechanisms associated with the functional role of SphK in normal and cancerous cells.

The second project, target validation, is closely associated with the physiological and/or pathological functions of SphK. To validate SphK as a therapeutic target, the lab currently has ongoing studies in collaboration with other investigators including clinicians such as oncologists and pathologists.

The third project, proof-of-concept studies, centers around the development of novel disease-specific and effective therapeutic approaches by targeting SphK. In this regard, Dr. Yun's work has already identified and refined novel SphK inhibitors (SKIs) by screening libraries of synthetic compounds. Currently, the lab has several ongoing proof-of-concept studies in collaboration with other investigators who have expertise medicinal chemistry, computational chemistry and in vivo mouse model systems.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Dive into the research topics where Jong Yun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Outstanding Collaborative Research Team

    Adair, James Hansell (Recipient), Amin, Shantu (Recipient), Claxton, David (Recipient), Desai, Dhimant (Recipient), Hengst, Jeremy (Recipient), Liao, Jiangang "Jason" (Recipient), Paulson, Robert (Recipient), Sharma, Arun (Recipient), Stanley, Bruce (Recipient), Wang, Hong-Gang (Recipient), Yun, Jong (Recipient) & Zhu, Junjia (Recipient), 2015

    Prize