Joseph M. Bollinger, Jr.

    • United States

    • 9032 Citations
    • 53 h-Index
    1989 …2020
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    Research Output 1989 2020

    2004
    24 Citations (Scopus)
    Ribonucleotide Reductases
    Escherichia coli Proteins
    Escherichia coli
    Chemical activation
    Proteins
    39 Citations (Scopus)

    Electronic and Spectroscopic Studies of the Non-Heme Reduced Binuclear Iron Sites of Two Ribonucleotide Reductase Variants: Comparison to Reduced Methane Monooxygenase and Contributions to O2 Reactivity

    Wei, P. P., Skulan, A. J., Mitić, N., Yang, Y. S., Saleh, L., Bollinger, Jr., J. M. & Solomon, E. I., Mar 31 2004, In : Journal of the American Chemical Society. 126, 12, p. 3777-3788 12 p.

    Research output: Contribution to journalArticle

    methane monooxygenase
    Ribonucleotide Reductases
    Dichroism
    Circular Dichroism
    Methane
    5 Citations (Scopus)
    Dioxygenases
    Biochemistry
    Escherichia coli
    Iron
    alpha-ketoglutaric acid
    223 Citations (Scopus)

    EXAFS spectroscopic evidence for an Fe=O unit in the Fe(IV) intermediate observed during oxygen activation by taurine:α-ketoglutarate dioxygenase

    Riggs-Gelasco, P. J., Price, J. C., Guyer, R. B., Brehm, J. H., Barr, E. W., Bollinger, Jr., J. M. & Krebs, C., Jul 7 2004, In : Journal of the American Chemical Society. 126, 26, p. 8108-8109 2 p.

    Research output: Contribution to journalArticle

    Dioxygenases
    Taurine
    Iron
    X-Ray Absorption Spectroscopy
    Chemical activation
    61 Citations (Scopus)

    Kinetic and structural characterization of Slr0077/SufS, the essential cysteine desulfurase from Synechocystis sp. PCC 6803

    Tirupati, B., Vey, J. L., Drennan, C. L. & Bollinger, Jr., J. M., Sep 28 2004, In : Biochemistry. 43, 38, p. 12210-12219 10 p.

    Research output: Contribution to journalArticle

    Synechocystis
    Cysteine
    Kinetics
    Proteins
    Thermotoga maritima
    37 Citations (Scopus)

    Mechanism of cysteine desulfurase Slr0387 from Synechocystis sp. PCC 6803: Kinetic analysis of cleavage of the persulfide intermediate by chemical reductants

    Behshad, E., Parkin, S. E. & Bollinger, J. M., Sep 28 2004, In : Biochemistry. 43, 38, p. 12220-12226 7 p.

    Research output: Contribution to journalArticle

    Synechocystis
    Reducing Agents
    Dithiothreitol
    Kinetics
    Cysteine
    12 Citations (Scopus)

    Mediation by indole analogues of electron transfer during oxygen activation in variants of Escherichia coli ribonucleotide reductase R2 lacking the electron-shuttling tryptophan 48

    Saleh, L., Kelch, B. A., Pathickal, B. A., Baldwin, J., Ley, B. A. & Bollinger, Jr., J. M., May 25 2004, In : Biochemistry. 43, 20, p. 5943-5952 10 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Tryptophan
    Escherichia coli
    Chemical activation
    Electrons
    70 Citations (Scopus)

    Nature of the peroxo intermediate of the W48F/D84E ribonucleotide reductase variant: Implications for O2 activation by binuclear non-heme iron enzymes

    Skulan, A. J., Brunold, T. C., Baldwin, J., Saleh, L., Bollinger, J. M. & Solomon, E. I., Jul 21 2004, In : Journal of the American Chemical Society. 126, 28, p. 8842-8855 14 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Iron
    Enzymes
    Chemical activation
    Geometry
    31 Citations (Scopus)

    Use of a chemical trigger for electron transfer to characterize a precursor to cluster X in assembly of the iron-radical cofactor of Escherichia coli ribonucleotide reductase

    Saleh, L., Krebs, C., Ley, B. A., Naik, S., Huynh, B. H. & Bollinger, Jr., J. M., May 25 2004, In : Biochemistry. 43, 20, p. 5953-5964 12 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    Iron
    Skatole
    Electrons
    2003
    283 Citations (Scopus)
    Dioxygenases
    Hydroxylation
    Taurine
    Hydrogen
    Chemical activation
    31 Citations (Scopus)

    Rapid-freeze-quench magnetic circular dichroism of intermediate X in ribonucleotide reductase: New structural insight

    Mitić, N., Saleh, L., Schenk, G., Bollinger, J. M. & Solomon, E. I., Sep 17 2003, In : Journal of the American Chemical Society. 125, 37, p. 11200-11201 2 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Dichroism
    Circular Dichroism
    Charge transfer
    Ligands
    37 Citations (Scopus)

    Structural Characterization of the Peroxodiiron(III) Intermediate Generated during Oxygen Activation by the W48A/D84E Variant of Ribonucleotide Reductase Protein R2 from Escherichia coli

    Baldwin, J., Krebs, C., Saleh, L., Stelling, M., Huynh, B. H., Bollinger, Jr., J. M. & Riggs-Gelasco, P., Nov 18 2003, In : Biochemistry. 42, 45, p. 13269-13279 11 p.

    Research output: Contribution to journalArticle

    methane monooxygenase
    Ribonucleotide Reductases
    Escherichia coli Proteins
    Escherichia coli
    Chemical activation
    459 Citations (Scopus)
    Dioxygenases
    Taurine
    Escherichia coli
    Iron
    Enzymes
    36 Citations (Scopus)

    Variable Coordination Geometries at the Diiron(II) Active Site of Ribonucleotide Reductase R2

    Voegtli, W. C., Sommerhalter, M., Saleh, L., Baldwin, J., Bollinger, Jr., J. M. & Rosenzweig, A. C., Dec 24 2003, In : Journal of the American Chemical Society. 125, 51, p. 15822-15830 9 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Catalytic Domain
    Proteins
    Geometry
    Dichroism
    2002
    26 Citations (Scopus)

    Exchange coupling constant J of peroxodiferric reaction intermediates determined by Mössbauer spectroscopy

    Krebs, C., Bollinger, Jr., J. M., Theil, E. C. & Huynh, B. H., Dec 1 2002, In : Journal of Biological Inorganic Chemistry. 7, 7-8, p. 863-869 7 p.

    Research output: Contribution to journalArticle

    Reaction intermediates
    Exchange coupling
    Ferritins
    Spectrum Analysis
    Spectroscopy
    26 Citations (Scopus)

    Facile electron transfer during formation of cluster X and kinetic competence of X for tyrosyl radical production in protein R2 of ribonucleotide reductase from mouse

    Yun, D., Krebs, C., Gupta, G. P., Iwig, D. F., Huynh, B. H. & Bollinger, J. M., Jan 22 2002, In : Biochemistry. 41, 3, p. 981-990 10 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Mental Competency
    Electrons
    Oxygen
    Escherichia coli
    2001
    69 Citations (Scopus)

    Rational reprogramming of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase

    Baldwin, J., Voegtli, W. C., Khidekel, N., Mönne-Loccoz, P., Krebs, C., Pereira, A. S., Ley, B. A., Huynh, B. H., Loehr, T. M., Riggs-Gelasco, P. J., Rosenzweig, A. C. & Bollinger, J. M., Oct 1 2001, In : Journal of the American Chemical Society. 123, 29, p. 7017-7030 14 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    methane monooxygenase
    Mixed Function Oxygenases
    Hydroxylation
    Escherichia coli
    2000
    52 Citations (Scopus)

    Crystal structure of the ribonucleotide reductase R2 mutant that accumulates a μ-1,2-peroxodiiron(III) intermediate during oxygen activation

    Voegtli, W. C., Khidekel, N., Baldwin, J., Ley, B. A., Bollinger, J. M. & Rosenzweig, A. C., Apr 12 2000, In : Journal of the American Chemical Society. 122, 14, p. 3255-3261 7 p.

    Research output: Contribution to journalArticle

    methane monooxygenase
    Ribonucleotide Reductases
    Crystal structure
    Chemical activation
    Ligands
    119 Citations (Scopus)

    Mechanism of rapid electron transfer during oxygen activation in the R2 subunit of Escherichia coli ribonucleotide reductase. 1. Evidence for a transient tryptophan radical

    Baldwin, J., Krebs, C., Ley, B. A., Edmondson, D. E., Huynh, B. H. & Bollinger, Jr., J. M., Dec 13 2000, In : Journal of the American Chemical Society. 122, 49, p. 12195-12206 12 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Tryptophan
    Escherichia coli
    Chemical activation
    Electrons
    66 Citations (Scopus)

    Mechanism of rapid electron transfer during oxygen activation in the R2 subunit of Escherichia coli ribonucleotide reductase. 2. Evidence for and consequences of blocked electron transfer in the W48F variant

    Krebs, C., Chen, S., Baldwin, J., Ley, B. A., Patel, U., Edmondson, D. E., Huynh, B. H. & Bollinger, J. M., Dec 13 2000, In : Journal of the American Chemical Society. 122, 49, p. 12207-12219 13 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    Chemical activation
    Electrons
    Oxygen
    20 Citations (Scopus)

    Mossbauer and EPR characterization of the S = 9/2 mixed-valence Fe(II)Fe(III) cluster in the cryoreduced R2 subunit of Escherichia coli ribonucleotide reductase

    Krebs, C., Davydov, R., Baldwin, J., Hoffman, B. M., Bollinger, J. M. & Huynh, B. H., Jun 7 2000, In : Journal of the American Chemical Society. 122, 22, p. 5327-5336 10 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    Paramagnetic resonance
    Chelation
    Electronic properties
    47 Citations (Scopus)
    Ribonucleotide Reductases
    Escherichia coli
    Electronic structure
    Catalytic Domain
    Iron
    1998
    52 Citations (Scopus)

    Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2

    Parkin, S. E., Chen, S., Ley, B. A., Mangravite, L., Edmondson, D. E., Huynh, B. H. & Bollinger, Jr., J. M., Jan 27 1998, In : Biochemistry. 37, 4, p. 1124-1130 7 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Electron injection
    Escherichia coli
    Chemical activation
    Electrons
    121 Citations (Scopus)
    methane monooxygenase
    Ribonucleotide Reductases
    Escherichia coli
    Proteins
    143 Citations (Scopus)

    O2 activation by non-heme diiron proteins: Identification of a symmetric μ-1,2-peroxide in a mutant of ribonucleotide reductase

    Moënne-Loccoz, P., Baldwin, J., Ley, B. A., Loehr, T. M. & Bollinger, Jr., J. M., Oct 20 1998, In : Biochemistry. 37, 42, p. 14659-14663 5 p.

    Research output: Contribution to journalArticle

    acyl-(acyl-carrier-protein)desaturase
    methane monooxygenase
    Ribonucleotide Reductases
    Peroxides
    Stretching
    4 Citations (Scopus)

    Reaction Intermediates in Oxygen Activation Reactions by Enzymes Containing Carboxylate-Bridged Binuclear Iron Clusters

    Huynh, B. H., Bollinger, Jr., J. M. & Edmondson, D. E., Dec 1 1998, In : ACS Symposium Series. 692, p. 403-422 20 p.

    Research output: Contribution to journalArticle

    methane monooxygenase
    Reaction intermediates
    Methane
    Iron
    Enzymes
    1997
    41 Citations (Scopus)

    Dissection of glutathionylspermidine synthetase/amidase from Escherichia coli into autonomously folding and functional synthetase and amidase domains

    Kwon, D. S., Lin, C. H., Chen, S., Coward, J. K., Walsh, C. T. & Bollinger, Jr., J. M., Feb 11 1997, In : Journal of Biological Chemistry. 272, 4, p. 2429-2436 8 p.

    Research output: Contribution to journalArticle

    glutathionylspermidine synthetase
    amidase
    Dissection
    Ligases
    Escherichia coli
    27 Citations (Scopus)

    Evidence for a glutathionyl-enzyme intermediate in the amidase activity of the bifunctional glutathionylspermidine synthetase/amidase from Escherichia coli

    Lin, C. H., Kwon, D. S., Bollinger, J. M. & Walsh, C. T., Dec 2 1997, In : Biochemistry. 36, 48, p. 14930-14938 9 p.

    Research output: Contribution to journalArticle

    glutathionylspermidine synthetase
    amidase
    Escherichia coli
    Enzymes
    Mutagenesis
    1995
    149 Citations (Scopus)

    Binuclear [2Fe-2S] clusters in the Escherichia coli SoxR protein and role of the metal centers in transcription

    Hidalgo, E., Bollinger, J. M., Bradley, T. M., Walsh, C. T. & Demple, B., Jan 1 1995, In : Journal of Biological Chemistry. 270, 36, p. 20908-20914 7 p.

    Research output: Contribution to journalArticle

    Escherichia coli Proteins
    Transcription
    Escherichia coli
    Iron
    Metals
    59 Citations (Scopus)
    Ribonucleoside Diphosphate Reductase
    Azides
    Circular Dichroism
    Escherichia coli
    Catalytic Domain
    80 Citations (Scopus)

    Glutathionylspermidine metabolism in Escherichia coli: Purification, cloning, overproduction, and characterization of a bifunctional glutathionylspermidine synthetase/amidase

    Bollinger, Jr., J. M., Kwon, D. S., Huisman, G. W., Kolter, R. & Walsh, C. T., Jun 9 1995, In : Journal of Biological Chemistry. 270, 23, p. 14031-14041 11 p.

    Research output: Contribution to journalArticle

    glutathionylspermidine synthetase
    amidase
    Spermidine
    Cloning
    Metabolism
    71 Citations (Scopus)

    Use of rapid kinetics methods to study the assembly of the diferric-tyrosyl radical cofactor of E. coli ribonucleotide reductase

    Bollinger, Jr., J. M., Hangtong, W., Ravi, N., Hanh Huynh, B., Edmondson, D. & Stubbe, J. A., Jan 1 1995, In : Methods in Enzymology. 258, C, p. 278-303 26 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    1994
    181 Citations (Scopus)

    Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. Coli Ribonucleotide Reductase. 1. Mössbauer Characterization of the Diferric Radical Precursor

    Ravi, N., Huynh, B. H., Edmondson, D. E., Bollinger, J. M. & Stubbe, J. A., Sep 1 1994, In : Journal of the American Chemical Society. 116, 18, p. 8007-8014 8 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    Iron
    Electron Spin Resonance Spectroscopy
    Paramagnetic resonance
    161 Citations (Scopus)

    Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. coli Ribonucleotide Reductase. 2. Kinetics of The Excess Fe2+Reaction by Optical, EPR, and Mossbauer Spectroscopies

    Bollinger, J. M., Tong, W. H., Stubbe, J. A., Ravi, N., Huynh, B. H. & Edmondson, D. E., Sep 1 1994, In : Journal of the American Chemical Society. 116, 18, p. 8015-8023 9 p.

    Research output: Contribution to journalArticle

    Mossbauer Spectroscopy
    Ribonucleotide Reductases
    Mossbauer spectroscopy
    Escherichia coli
    Paramagnetic resonance
    131 Citations (Scopus)

    Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. coli Ribonucleotide Reductase. 3. Kinetics of the Limiting Fe2+Reaction by Optical, EPR, and Mossbauer Spectroscopies

    Bollinger, J. M., Tong, W. H., Stubbe, J. A., Huynh, B. H., Edmondson, D. E. & Ravi, N., Sep 1 1994, In : Journal of the American Chemical Society. 116, 18, p. 8024-8032 9 p.

    Research output: Contribution to journalArticle

    Mossbauer Spectroscopy
    Ribonucleotide Reductases
    Mossbauer spectroscopy
    Escherichia coli
    Paramagnetic resonance
    1993
    53 Citations (Scopus)

    Alternative Model for Mechanism-Based Inhibition of Escherichia coli Ribonucleotide Reductase by 2′-Azido-2′-deoxyuridine 5′-Diphosphate

    Salowe, S., Bollinger, J. M., Ator, M., Stubbe, J., McCracken, J., Peisach, J., Samano, M. C. & Robins, M. J., Jan 1 1993, In : Biochemistry. 32, 47, p. 12749-12760 12 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Escherichia coli
    Nitrogen
    Azides
    Nucleotides
    101 Citations (Scopus)

    High-Frequency (139.5 GHz) EPR Spectroscopy of the Tyrosyl Radical in Escberichia coli Ribonucleotide Reductase

    Gerfen, G. J., Bellew, B. F., Un, S., Griffin, R. G., Bellew, B. F., Bollinger, Jr., J. M., Stubbe, J., Griffin, R. G. & Singel, D. J., Jul 1 1993, In : Journal of the American Chemical Society. 115, 14, p. 6420-6421 2 p.

    Research output: Contribution to journalEditorial

    Ribonucleotide Reductases
    Paramagnetic resonance
    Spectrum Analysis
    Spectroscopy
    Oxidoreductases
    1992
    186 Citations (Scopus)

    A Model for the Role of Multiple Cysteine Residues Involved in Ribonucleotide Reduction: Amazing and Still Confusing

    Mao, S. S., Holler, T. P., Yu, G. X., Bollinger, Jr., J. M., Booker, S. J., Johnston, M. I. & Stubbe, J., Feb 1 1992, In : Biochemistry. 31, 40, p. 9733-9743 11 p.

    Research output: Contribution to journalArticle

    Ribonucleotides
    Thioredoxins
    Cysteine
    Reducing Agents
    Thioredoxin-Disulfide Reductase
    55 Citations (Scopus)

    Interaction of C225SR1 Mutant Subunit of Ribonucleotide Reductase with R2 and Nucleoside Diphosphates: Tales of a Suicidal Enzyme

    Mao, S. S., Holler, T. P., Bollinger, Jr., J. M., Yu, G. X., Johnston, M. I. & Stubbe, J., Feb 1 1992, In : Biochemistry. 31, 40, p. 9744-9751 8 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Diphosphates
    Nucleosides
    Peptides
    Uridine Diphosphate
    1991
    219 Citations (Scopus)

    2′-Deoxy-2′-methylenecytidine and 2′-Deoxy-2′,2′-difluorocytidine 5′-Diphosphates: Potent Mechanism-Based Inhibitors of Ribonucleotide Reductase

    Baker, C. H., Banzon, J., Bollinger, J. M., Stubbe, J., Samano, V., Robins, M. J., Lippert, B., Jarvi, E. & Resvick, R., Jun 1 1991, In : Journal of Medicinal Chemistry. 34, 6, p. 1879-1884 6 p.

    Research output: Contribution to journalArticle

    gemcitabine
    Ribonucleoside Diphosphate Reductase
    Ribonucleotide Reductases
    Diphosphates
    Uridine
    319 Citations (Scopus)

    Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase

    Bollinger, Jr., J. M., Edmondson, D. E., Huynh, B. H., Filley, J., Norton, J. R. & Stubbe, J., Jan 1 1991, In : Science. 253, 5017, p. 292-298 7 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Electron Spin Resonance Spectroscopy
    Iron
    Spectrum Analysis
    Peroxidases
    81 Citations (Scopus)

    Novel Diferric Radical Intermediate Responsible for Tyrosyl Radical Formation in Assembly of the Cofactor of Ribonucleotide Reductase

    Bollinger, J. M., Stubbe, J. A., Huynh, B. H. & Edmondson, D. E., Jul 1 1991, In : Journal of the American Chemical Society. 113, 16, p. 6289-6291 3 p.

    Research output: Contribution to journalArticle

    Ribonucleotide Reductases
    Oxidoreductases
    1989
    35 Citations (Scopus)
    Cytidine Diphosphate
    Ribonucleotide Reductases
    Cysteine
    Reducing Agents
    Escherichia coli