Joseph M. Bollinger, Jr. &ndash; Research Output

2020

High-resolution iron X-ray absorption spectroscopic and computational studies of non-heme diiron peroxo intermediates

Cutsail, G. E., Blaesi, E. J., Pollock, C. J., Bollinger, J. M., Krebs, C. & DeBeer, S., Feb 2020, In : Journal of Inorganic Biochemistry. 203, 110877.

Research output: Contribution to journal › Article

Open Access

X-Ray Absorption Spectroscopy

X ray absorption spectroscopy

X ray absorption

Iron

Fluorescence

2019

1 Citation (Scopus)

A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases

Rajakovich, L. J., Pandelia, M. E., Mitchell, A. J., Chang, W. C., Zhang, B., Boal, A. K., Krebs, C. & Bollinger, J. M., Mar 26 2019, In : Biochemistry. 58, 12, p. 1627-1647 21 p.

Research output: Contribution to journal › Article

Organophosphonates

Oxygenases

Iron

Degradation

gamma-Butyrobetaine Dioxygenase

2 Citations (Scopus)

Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Dunham, N. P., Del Río Pantoja, J. M., Zhang, B., Rajakovich, L. J., Allen, B. D., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9964-9979 16 p.

Research output: Contribution to journal › Article

Tyrosine

Hydrogen

Atoms

Carbon

Iron

2 Citations (Scopus)

Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants

Chekan, J. R., Ongpipattanakul, C., Wright, T. R., Zhang, B., Bollinger, Jr., J. M., Rajakovich, L. J., Krebs, C., Cicchillo, R. M. & Nair, S. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13299-13304 6 p.

Research output: Contribution to journal › Article

Open Access

Dioxygenases

Genetically Modified Plants

Herbicides

2,4-Dichlorophenoxyacetic Acid

Indoleacetic Acids

Structure of a Ferryl Mimic in the Archetypal Iron(II)- And 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD

Davis, K. M., Altmyer, M., Martinie, R. J., Schaperdoth, I., Krebs, C., Bollinger, J. M. & Boal, A. K., Oct 15 2019, In : Biochemistry. 58, 41, p. 4218-4223 6 p.

Research output: Contribution to journal › Article

Glutarates

Dioxygenases

Taurine

Iron

Hydroxylation

Substrate-Triggered Formation of a Peroxo-Fe₂(III/III) Intermediate during Fatty Acid Decarboxylation by UndA

Zhang, B., Rajakovich, L. J., Van Cura, D., Blaesi, E. J., Mitchell, A. J., Tysoe, C. R., Zhu, X., Streit, B. R., Rui, Z., Zhang, W., Boal, A. K., Krebs, C. & Bollinger, J. M., Sep 18 2019, In : Journal of the American Chemical Society. 141, 37, p. 14510-14514 5 p.

Research output: Contribution to journal › Article

Decarboxylation

Fatty acids

lauric acid

Fatty Acids

Iron

2018

8 Citations (Scopus)

Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions

Pan, J., Bhardwaj, M., Zhang, B., Chang, W. C., Schardl, C. L., Krebs, C., Grossman, R. B. & Martin Bollinger, J., Apr 10 2018, In : Biochemistry. 57, 14, p. 2074-2083 10 p.

Research output: Contribution to journal › Article

Oxygenases

Hydroxylation

Stereochemistry

Ether

Iron

8 Citations (Scopus)

Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosinederived dihydroxyphenylalanine radical

Blaesi, E. J., Palowitch, G. M., Hu, K., Kim, A. J., Rose, H. R., Alapati, R., Lougee, M. G., Kim, H. J., Taguchi, A. T., Tan, K. O., Laremore, T. N., Griffin, R. G., Krebs, C., Matthews, M. L., Silakov, A., Bollinger, J. M., Allen, B. D. & Boal, A. K., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10022-10027 6 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Dihydroxyphenylalanine

Catalysis

Metals

Tissue Plasminogen Activator

11 Citations (Scopus)

Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class i Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor

Rose, H. R., Ghosh, M. K., Maggiolo, A. O., Pollock, C. J., Blaesi, E. J., Hajj, V., Wei, Y., Rajakovich, L. J., Chang, W. C., Han, Y., Hajj, M., Krebs, C., Silakov, A., Pandelia, M. E., Bollinger, J. M. & Boal, A. K., May 8 2018, In : Biochemistry. 57, 18, p. 2679-2693 15 p.

Research output: Contribution to journal › Article

Flavobacterium

Ribonucleotide Reductases

Superoxides

Chemical activation

Proteins

19 Citations (Scopus)

The biosynthesis of methanobactin

Kenney, G. E., Dassama, L. M. K., Pandelia, M. E., Gizzi, A. S., Martinie, R. J., Gao, P., DeHart, C. J., Schachner, L. F., Skinner, O. S., Ro, S. Y., Zhu, X., Sadek, M., Thomas, P. M., Almo, S. C., Bollinger, J. M., Krebs, C., Kelleher, N. L. & Rosenzweig, A. C., Mar 23 2018, In : Science. 359, 6382, p. 1411-1416 6 p.

Research output: Contribution to journal › Article

Copper

Iron

Thioamides

Metals

Oxazolone

1 Citation (Scopus)

Two-Color Valence-to-Core X-ray Emission Spectroscopy Tracks Cofactor Protonation State in a Class I Ribonucleotide Reductase

Martinie, R. J., Blaesi, E. J., Bollinger, Jr., J. M., Krebs, C., Finkelstein, K. D. & Pollock, C. J., Sep 24 2018, In : Angewandte Chemie - International Edition. 57, 39, p. 12754-12758 5 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Protonation

Proton transfer

Color

Enzymes

18 Citations (Scopus)

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance

Dunham, N. P., Chang, W. C., Mitchell, A. J., Martinie, R. J., Zhang, B., Bergman, J. A., Rajakovich, L. J., Wang, B., Silakov, A., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 13 2018, In : Journal of the American Chemical Society. 140, 23, p. 7116-7126 11 p.

Research output: Contribution to journal › Article

Glutarates

Oxygenases

Hydroxylation

Carbon

Homoarginine

5 Citations (Scopus)

α-Amine Desaturation of d -Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l -Arginine 3-Hydroxylase, VioC

Dunham, N. P., Mitchell, A. J., Del Río Pantoja, J. M., Krebs, C., Bollinger, J. M. & Boal, A. K., Nov 20 2018, In : Biochemistry. 57, 46, p. 6479-6488 10 p.

Research output: Contribution to journal › Article

Glutarates

Hydroxylation

Mixed Function Oxygenases

Amines

Arginine

2017

46 Citations (Scopus)

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

Fuller, F. D., Gul, S., Chatterjee, R., Sethe Burgie, E., Young, I. D., Lebrette, H., Srinivas, V., Brewster, A. S., Michels-Clark, T., Clinger, J. A., Andi, B., Ibrahim, M., Pastor, E., De Lichtenberg, C., Hussein, R., Pollock, C. J., Zhang, M., Stan, C. A., Kroll, T., Fransson, T. & 36 others, Weninger, C., Kubin, M., Aller, P., Lassalle, L., Bräuer, P., Miller, M. D., Amin, M., Koroidov, S., Roessler, C. G., Allaire, M., Sierra, R. G., Docker, P. T., Glownia, J. M., Nelson, S., Koglin, J. E., Zhu, D., Chollet, M., Song, S., Lemke, H., Liang, M., Sokaras, D., Alonso-Mori, R., Zouni, A., Messinger, J., Bergmann, U., Boal, A. K., Martin Bollinger, J., Krebs, C., Högbom, M., Phillips, G. N., Vierstra, R. D., Sauter, N. K., Orville, A. M., Kern, J., Yachandra, V. K. & Yano, J., Feb 27 2017, In : Nature methods. 14, 4, p. 443-449 7 p.

Research output: Contribution to journal › Article

Belt drives

Phytochrome

X ray lasers

Ribonucleotide Reductases

Crystallography

9 Citations (Scopus)

Evidence for a Di-μ-oxo diamond core in the Mn(IV)/Fe(IV) activation intermediate of ribonucleotide reductase from chlamydia trachomatis

Martinie, R. J., Blaesi, E. J., Krebs, C., Bollinger, Jr., J. M., Silakov, A. & Pollock, C. J., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 1950-1957 8 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Diamond

Chlamydia trachomatis

Electron Spin Resonance Spectroscopy

X ray absorption

10 Citations (Scopus)

O-H activation by an unexpected ferryl intermediate during catalysis by 2-hydroxyethylphosphonate dioxygenase

Peck, S. C., Wang, C., Dassama, L. M. K., Zhang, B., Guo, Y., Rajakovich, L. J., Martin Bollinger, J., Krebs, C. & Van Der Donk, W. A., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 2045-2052 8 p.

Research output: Contribution to journal › Article

Dioxygenases

Catalysis

Chemical activation

Deuterium

Herbicides

11 Citations (Scopus)

Peroxide Activation for Electrophilic Reactivity by the Binuclear Non-heme Iron Enzyme AurF

Park, K., Li, N., Kwak, Y., Srnec, M., Bell, C. B., Liu, L. V., Wong, S. D., Yoda, Y., Kitao, S., Seto, M., Hu, M., Zhao, J., Krebs, C., Bollinger, J. M. & Solomon, E. I., May 24 2017, In : Journal of the American Chemical Society. 139, 20, p. 7062-7070 9 p.

Research output: Contribution to journal › Article

Protonation

Peroxides

para-Aminobenzoates

Iron

Enzymes

6 Citations (Scopus)

Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes

Martinie, R. J., Pollock, C. J., Matthews, M. L., Bollinger, Jr., J. M., Krebs, C. & Silakov, A., Nov 6 2017, In : Inorganic Chemistry. 56, 21, p. 13382-13389 8 p.

Research output: Contribution to journal › Article

Vanadates

enzymes

Iron

iron

Substrates

29 Citations (Scopus)

Visualizing the reaction cycle in an Iron(II)- and 2-(Oxo)-glutarate-dependent hydroxylase

Mitchell, A. J., Dunham, N. P., Martinie, R. J., Bergman, J. A., Pollock, C. J., Hu, K., Allen, B. D., Chang, W. C., Silakov, A., Bollinger, Jr., J. M., Krebs, C. & Boal, A. K., Jan 1 2017, In : Journal of the American Chemical Society. 139, 39, p. 13830-13836 7 p.

Research output: Contribution to journal › Article

Glutarates

Oxygenases

Vanadium

Mixed Function Oxygenases

Arginine

2016

29 Citations (Scopus)

Electronic Structure of the Ferryl Intermediate in the α-Ketoglutarate Dependent Non-Heme Iron Halogenase SyrB2: Contributions to H Atom Abstraction Reactivity

Srnec, M., Wong, S. D., Matthews, M. L., Krebs, C., Bollinger, Jr., J. M. & Solomon, E. I., May 4 2016, In : Journal of the American Chemical Society. 138, 15, p. 5110-5122 13 p.

Research output: Contribution to journal › Article

Anisotropy

Molecular orbitals

Electronic structure

Spectrum Analysis

Iron

46 Citations (Scopus)

Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase

Tamanaha, E., Zhang, B., Guo, Y., Chang, W. C., Barr, E. W., Xing, G., St Clair, J., Ye, S., Neese, F., Bollinger, Jr., J. M. & Krebs, C., Jul 20 2016, In : Journal of the American Chemical Society. 138, 28, p. 8862-8874 13 p.

Research output: Contribution to journal › Article

Thiazolidines

Aspergillus nidulans

Lactams

Aspergillus

Iron

2015

4 Citations (Scopus)

Direct Measurement of the Radical Translocation Distance in the Class i Ribonucleotide Reductase from Chlamydia trachomatis

Livada, J., Martinie, R. J., Dassama, L. M. K., Krebs, C., Bollinger, Jr., J. M. & Silakov, A., Oct 29 2015, In : Journal of Physical Chemistry B. 119, 43, p. 13777-13784 8 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Electron resonance

Deoxyribonucleotides

diphosphates

Ribonucleotides

12 Citations (Scopus)

Efficient delivery of long-chain fatty aldehydes from the nostoc punctiforme acyl-acyl carrier protein reductase to its cognate aldehyde-deformylating oxygenase

Warui, D., Pandelia, M. E., Rajakovich, L. J., Krebs, C., Bollinger, Jr., J. M. & Booker, S. J., Feb 3 2015, In : Biochemistry. 54, 4, p. 1006-1015 10 p.

Research output: Contribution to journal › Article

Nostoc

Acyl Carrier Protein

Oxygenases

Aldehydes

Oxidoreductases

32 Citations (Scopus)

Experimental correlation of substrate position with reaction outcome in the aliphatic halogenase, SyrB2

Martinie, R. J., Livada, J., Chang, W. C., Green, M. T., Krebs, C., Bollinger, Jr., J. M. & Silakov, A., Jun 3 2015, In : Journal of the American Chemical Society. 137, 21, p. 6912-6919 8 p.

Research output: Contribution to journal › Article

Threonine

Glutarates

Aminobutyrates

Oxygenases

Deuterium

26 Citations (Scopus)

Rapid Reduction of the Diferric-Peroxyhemiacetal Intermediate in Aldehyde-Deformylating Oxygenase by a Cyanobacterial Ferredoxin: Evidence for a Free-Radical Mechanism

Rajakovich, L. J., Nørgaard, H., Warui, D., Chang, W. C., Li, N., Booker, S. J., Krebs, C., Bollinger, Jr., J. M. & Pandelia, M. E., Sep 16 2015, In : Journal of the American Chemical Society. 137, 36, p. 11695-11709 15 p.

Research output: Contribution to journal › Article

formic acid

Ferredoxins

Oxygenases

Aldehydes

Free radicals

2014

56 Citations (Scopus)

Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase

Matthews, M. L., Chang, W. C., Layne, A. P., Miles, L. A., Krebs, C. & Bollinger, J. M., Mar 2014, In : Nature Chemical Biology. 10, 3, p. 209-215 7 p.

Research output: Contribution to journal › Article

Anions

Carbon

Iron

Decarboxylation

Halogens

58 Citations (Scopus)

Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics

Chang, W. C., Guo, Y., Wang, C., Butch, S. E., Rosenzweig, A. C., Boal, A. K., Krebs, C. & Bollinger, Jr., J. M., Jan 1 2014, In : Science. 343, 6175, p. 1140-1144 5 p.

Research output: Contribution to journal › Article

Lactams

Carbapenems

Tyrosine

Glutarates

Oxygenases

2013

23 Citations (Scopus)

A 2.8 Å Fe-Fe separation in the Fe ₂ ^III/IV intermediate, X, from Escherichia coli ribonucleotide reductase

Dassama, L. M. K., Silakov, A., Krest, C. M., Calixto, J. C., Krebs, C., Bollinger, Jr., J. M. & Green, M. T., Nov 13 2013, In : Journal of the American Chemical Society. 135, 45, p. 16758-16761 4 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

X ray absorption

Escherichia coli

chlorite dismutase

X-Rays

4 Citations (Scopus)

Circular dichroism, magnetic circular dichroism, and variable temperature variable field magnetic circular dichroism studies of biferrous and mixed-valent myo -inositol oxygenase: Insights into substrate activation of O₂ reactivity

Snyder, R. A., Bell, C. B., Diao, Y., Krebs, C., Bollinger, J. M. & Solomon, E. I., Oct 31 2013, In : Journal of the American Chemical Society. 135, 42, p. 15851-15863 13 p.

Research output: Contribution to journal › Article

Inositol Oxygenase

Dichroism

Inositol

Magnetic Fields

Circular Dichroism

106 Citations (Scopus)

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

Wong, S. D., Srnec, M., Matthews, M. L., Liu, L. V., Kwak, Y., Park, K., Bell, C. B., Alp, E. E., Zhao, J., Yoda, Y., Kitao, S., Seto, M., Krebs, C., Bollinger, Jr., J. M. & Solomon, E. I., Jul 26 2013, In : Nature. 499, 7458, p. 320-323 4 p.

Research output: Contribution to journal › Article

Halogenation

Enzymes

Hydroxylation

Spectrum Analysis

Pseudomonas syringae

34 Citations (Scopus)

Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase

Wang, C., Chang, W. C., Guo, Y., Huang, H., Peck, S. C., Pandelia, M. E., Lin, G. M., Liu, H. W., Krebs, C. & Bollinger, Jr., J. M., Jan 1 2013, In : Science. 342, 6161, p. 991-995 5 p.

Research output: Contribution to journal › Article

Fosfomycin

Organophosphonates

Epoxy Compounds

Peroxidase

Iron

29 Citations (Scopus)

Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer

Wörsdörfer, B., Conner, D. A., Yokoyama, K., Livada, J., Seyedsayamdost, M., Jiang, W., Silakov, A., Stubbe, J., Bollinger, J. M. & Krebs, C., Jun 12 2013, In : Journal of the American Chemical Society. 135, 23, p. 8585-8593 9 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Proton transfer

Escherichia coli

Protons

Amino acids

21 Citations (Scopus)

Geometric and electronic structure of the Mn(IV)Fe(III) cofactor in class Ic ribonucleotide reductase: Correlation to the class ia binuclear non-heme iron enzyme

Kwak, Y., Jiang, W., Dassama, L. M. K., Park, K., Bell, C. B., Liu, L. V., Wong, S. D., Saito, M., Kobayashi, Y., Kitao, S., Seto, M., Yoda, Y., Alp, E. E., Zhao, J., Bollinger, J. M., Krebs, C. & Solomon, E. I., Nov 20 2013, In : Journal of the American Chemical Society. 135, 46, p. 17573-17584 12 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Vibrational spectroscopy

Dichroism

Electronic structure

Spectrum Analysis

18 Citations (Scopus)

Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases

Wörsdörfer, B., Lingaraju, M., Yennawar, N. H., Boal, A. K., Krebs, C., Bollinger, J. M. & Pandelia, M. E., Nov 19 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. 18874-18879 6 p.

Research output: Contribution to journal › Article

Inositol Oxygenase

Organophosphonates

Oxygenases

X Ray Crystallography

Phosphoric Monoester Hydrolases

20 Citations (Scopus)

Structural basis for assembly of the Mn^IV/Fe^III cofactor in the class ic ribonucleotide reductase from chlamydia trachomatis

Dassama, L. M. K., Krebs, C., Bollinger, Jr., J. M., Rosenzweig, A. C. & Boal, A. K., Sep 17 2013, In : Biochemistry. 52, 37, p. 6424-6436 13 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Chlamydia trachomatis

Apoproteins

Metals

Chemical activation

43 Citations (Scopus)

Substrate-triggered addition of dioxygen to the diferrous cofactor of aldehyde-deformylating oxygenase to form a diferric-peroxide intermediate

Pandelia, M. E., Li, N., Nørgaard, H., Warui, D., Rajakovich, L. J., Chang, W. C., Booker, S. J., Krebs, C. & Bollinger, Jr., J. M., Oct 31 2013, In : Journal of the American Chemical Society. 135, 42, p. 15801-15812 12 p.

Research output: Contribution to journal › Article

formic acid

Oxygenases

Peroxides

Aldehydes

Oxygen

37 Citations (Scopus)

The COMBREX Project: Design, Methodology, and Initial Results

Anton, B. P., Chang, Y. C., Brown, P., Choi, H. P., Faller, L. L., Guleria, J., Hu, Z., Klitgord, N., Levy-Moonshine, A., Maksad, A., Mazumdar, V., McGettrick, M., Osmani, L., Pokrzywa, R., Rachlin, J., Swaminathan, R., Allen, B., Housman, G., Monahan, C., Rochussen, K. & 54 others, Tao, K., Bhagwat, A. S., Brenner, S. E., Columbus, L., de Crécy-Lagard, V., Ferguson, D., Fomenkov, A., Gadda, G., Morgan, R. D., Osterman, A. L., Rodionov, D. A., Rodionova, I. A., Rudd, K. E., Söll, D., Spain, J., Xu, S. Y., Bateman, A., Blumenthal, R. M., Bollinger, J. M., Chang, W. S., Ferrer, M., Friedberg, I., Galperin, M. Y., Gobeill, J., Haft, D., Hunt, J., Karp, P., Klimke, W., Krebs, C., Macelis, D., Madupu, R., Martin, M. J., Miller, J. H., O'Donovan, C., Palsson, B., Ruch, P., Setterdahl, A., Sutton, G., Tate, J., Yakunin, A., Tchigvintsev, D., Plata, G., Hu, J., Greiner, R., Horn, D., Sjölander, K., Salzberg, S. L., Vitkup, D., Letovsky, S., Segrè, D., DeLisi, C., Roberts, R. J., Steffen, M. & Kasif, S., Aug 1 2013, In : PLoS biology. 11, 8, e1001638.

Research output: Contribution to journal › Article

2012

56 Citations (Scopus)

Electronic structure analysis of the oxygen-activation mechanism by Fe ^II- and α-ketoglutarate (αKG)-dependent dioxygenases

Ye, S., Riplinger, C., Hansen, A., Krebs, C., Bollinger, J. M. & Neese, F., May 21 2012, In : Chemistry - A European Journal. 18, 21, p. 6555-6567 13 p.

Research output: Contribution to journal › Article

Dioxygenases

Electronic structure

Chemical activation

Oxygen

Superoxides

85 Citations (Scopus)

Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases

Li, N., Chang, W. C., Warui, D., Booker, S. J., Krebs, C. & Bollinger, Jr., J. M., Oct 9 2012, In : Biochemistry. 51, 40, p. 7908-7916 9 p.

Research output: Contribution to journal › Article

formic acid

Aldehydes

Nostoc

Wetlands

Prochlorococcus

31 Citations (Scopus)

Evidence that the β subunit of chlamydia trachomatis ribonucleotide reductase is active with the manganese ion of its manganese(IV)/iron(III) cofactor in site 1

Dassama, L. M. K., Boal, A. K., Krebs, C., Rosenzweig, A. C. & Bollinger, Jr., J. M., Feb 8 2012, In : Journal of the American Chemical Society. 134, 5, p. 2520-2523 4 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Chlamydia trachomatis

Manganese

Iron

Ions

20 Citations (Scopus)

O ₂-evolving chlorite dismutase as a tool for studying O ₂-utilizing enzymes

Dassama, L. M. K., Yosca, T. H., Conner, D. A., Lee, M. H., Blanc, B., Streit, B. R., Green, M. T., DuBois, J. L., Krebs, C. & Bollinger, Jr., J. M., Feb 28 2012, In : Biochemistry. 51, 8, p. 1607-1616 10 p.

Research output: Contribution to journal › Article

chlorite dismutase

Kinetics

Enzymes

Solubility

Gases

4 Citations (Scopus)

Radical-translocation intermediates and hurdling of pathway defects in "super-oxidized" (Mn^IV/Fe^IV) Chlamydia trachomatis ribonucleotide reductase

Dassama, L. M. K., Jiang, W., Varano, P. T., Pandelia, M. E., Conner, D. A., Xie, J., Bollinger, Jr., J. M. & Krebs, C., Dec 19 2012, In : Journal of the American Chemical Society. 134, 50, p. 20498-20506 9 p.

Research output: Contribution to journal › Article

Ribonucleotide Reductases

Chlamydia trachomatis

Defects

Enzymes

Proteins

2011

12 Citations (Scopus)

Branched intermediate formation is the slowest step in the protein splicing reaction of the Ala1 KlbA intein from methanococcus jannaschii

Saleh, L., Southworth, M. W., Considine, N., O'Neill, C., Benner, J., Bollinger, J. M. & Perler, F. B., Dec 13 2011, In : Biochemistry. 50, 49, p. 10576-10589 14 p.

Research output: Contribution to journal › Article

Methanocaldococcus

Inteins

Protein Splicing

Proteins

Dithiothreitol

80 Citations (Scopus)

Conversion of fatty aldehydes to alka(e)nes and formate by a cyanobacterial aldehyde decarbonylase: Cryptic redox by an unusual dimetal oxygenase

Li, N., Nørgaard, H., Warui, D., Booker, S. J., Krebs, C. & Bollinger, Jr., J. M., Apr 27 2011, In : Journal of the American Chemical Society. 133, 16, p. 6158-6161 4 p.

Research output: Contribution to journal › Article

formic acid

Oxygenases

Aldehydes

Oxidation-Reduction

Nostoc

86 Citations (Scopus)

Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase

Warui, D., Li, N., Nørgaard, H., Krebs, C., Bollinger, Jr., J. M. & Booker, S. J., Mar 16 2011, In : Journal of the American Chemical Society. 133, 10, p. 3316-3319 4 p.

Research output: Contribution to journal › Article

formic acid

Alkanes

Carbon Monoxide

Aldehydes

Carbon monoxide

57 Citations (Scopus)

Evidence for a high-Spin Fe(IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylase

Panay, A. J., Lee, M., Krebs, C., Bollinger, Jr., J. M. & Fitzpatrick, P. F., Mar 22 2011, In : Biochemistry. 50, 11, p. 1928-1933 6 p.

Research output: Contribution to journal › Article

Phenylalanine Hydroxylase

Phenylalanine

Tyrosine

Rate constants

Nonheme Iron Proteins

2010

40 Citations (Scopus)

Cryoreduction of the NO-Adduct of Taurine: α-Ketoglutarate Dioxygenase (TauD) Yields an Elusive {FeNO}⁸ Species

Ye, S., Price, J. C., Barr, E. W., Green, M. T., Bollinger, J. M., Krebs, C. & Neese, F., Apr 7 2010, In : Journal of the American Chemical Society. 132, 13, p. 4739-4751 13 p.

Research output: Contribution to journal › Article

Dioxygenases

Taurine

Reaction intermediates

Enzymes

Ground state

48 Citations (Scopus)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen

Flashman, E., Hoffart, L. M., Hamed, R. B., Bollinger, J. M., Krebs, C. & Schofield, C. J., Oct 2010, In : FEBS Journal. 277, 19, p. 4089-4099 11 p.

Research output: Contribution to journal › Article

Hypoxia-Inducible Factor-Proline Dioxygenases

Prolyl Hydroxylases

Oxygenases

Oxygen

Oxygen sensors

41 Citations (Scopus)

Four-electron oxidation of p-hydroxylaminobenzoate to p-nitrobenzoate by a peroxodiferric complex in AurF from Streptomyces thioluteus

Li, N., Korboukh, V. K., Krebs, C. & Bollinger, J. M., Sep 7 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 36, p. 15722-15727 6 p.

Research output: Contribution to journal › Article

Nitrobenzoates

Streptomyces

Electrons

Oxygenases

para-Aminobenzoates

20 Citations (Scopus)

The nonribosomal peptide synthetase enzyme DdaD tethers N _β-fumaramoyl-l -2,3-diaminopropionate for Fe(II)/α- ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis

Hollenhorst, M. A., Bumpus, S. B., Matthews, M. L., Bollinger, Jr., J. M., Kelleher, N. L. & Walsh, C. T., Nov 10 2010, In : Journal of the American Chemical Society. 132, 44, p. 15773-15781 9 p.

Research output: Contribution to journal › Article

Peptide Synthases

Epoxidation

Biosynthesis

Antibiotics

Peptides