• 6955 Citations
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20012019
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Research Output 2001 2019

2011
56 Citations (Scopus)

(-)-Epigallocatechin-3-gallate increases the expression of genes related to fat oxidation in the skeletal muscle of high fat-fed mice

Sae-Tan, S., Grove, K. A., Kennett, M. J. & Lambert, J. D., Feb 1 2011, In : Food and Function. 2, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

epigallocatechin
skeletal muscle
Skeletal Muscle
Fats
oxidation
17 Citations (Scopus)

A Colored Avocado Seed Extract as a Potential Natural Colorant

Dabas, D., Elias, R., Lambert, J. D. & Ziegler, G. R., Nov 1 2011, In : Journal of Food Science. 76, 9

Research output: Contribution to journalArticle

Persea
avocados
seed extracts
Seeds
Color
92 Citations (Scopus)

Inhibition of key digestive enzymes by cocoa extracts and procyanidins

Gu, Y., Hurst, W. J., Stuart, D. A. & Lambert, J. D., May 25 2011, In : Journal of agricultural and food chemistry. 59, 10, p. 5305-5311 7 p.

Research output: Contribution to journalArticle

Cocoa
Proanthocyanidins
procyanidins
digestive enzymes
Lipase
9 Citations (Scopus)

Research on tea and health

Yang, C. S. & Lambert, J. D., Aug 1 2011, In : Pharmacological Research. 64, 2, p. 85-86 2 p.

Research output: Contribution to journalEditorial

Tea
Health
Research
218 Citations (Scopus)

The chemistry and biotransformation of tea constituents

Sang, S., Lambert, J. D., Ho, C. T. & Yang, C. S., Jan 1 2011, In : Pharmacological Research. 64, 2, p. 87-99 13 p.

Research output: Contribution to journalArticle

Tea
Biotransformation
Catechin
Insurance Benefits
Theaceae
155 Citations (Scopus)

The role of antioxidant versus pro-oxidant effects of green tea polyphenols in cancer prevention

Forester, S. C. & Lambert, J. D., Jun 1 2011, In : Molecular Nutrition and Food Research. 55, 6, p. 844-854 11 p.

Research output: Contribution to journalReview article

Polyphenols
green tea
Tea
oxidants
Reactive Oxygen Species
115 Citations (Scopus)

Weight control and prevention of metabolic syndrome by green tea

Sae-Tan, S., Grove, K. A. & Lambert, J. D., Aug 1 2011, In : Pharmacological Research. 64, 2, p. 146-154 9 p.

Research output: Contribution to journalReview article

Camellia sinensis
Weights and Measures
Lipogenesis
Catechin
Dietary Fats
2010
50 Citations (Scopus)

Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate

Lambert, J. D., Sang, S., Hong, J. & Yang, C. S., Sep 22 2010, In : Journal of agricultural and food chemistry. 58, 18, p. 10016-10019 4 p.

Research output: Contribution to journalArticle

epigallocatechin
Polyphenols
green tea
Tea
Metabolites
217 Citations (Scopus)

Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice

Lambert, J. D., Kennett, M. J., Sang, S., Reuhl, K. R., Ju, J. & Yang, C. S., Jan 1 2010, In : Food and Chemical Toxicology. 48, 1, p. 409-416 8 p.

Research output: Contribution to journalArticle

hepatotoxicity
epigallocatechin
mouth
mice
dosage
123 Citations (Scopus)

Laboratory, epidemiological, and human intervention studies show that tea (Camellia sinensis) may be useful in the prevention of obesity

Grove, K. A. & Lambert, J. D., Mar 1 2010, In : Journal of Nutrition. 140, 3, p. 446-453 8 p.

Research output: Contribution to journalReview article

Camellia sinensis
Tea
Obesity
Polyphenols
Theaceae
422 Citations (Scopus)
Polyphenols
Tea
Reactive Oxygen Species
Antioxidants
Catechin
2009
187 Citations (Scopus)

Antioxidative and anti-carcinogenic activities of tea polyphenols

Yang, C. S., Lambert, J. D. & Sang, S., Jan 1 2009, In : Archives of Toxicology. 83, 1, p. 11-21 11 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
Camellia sinensis
Neoplasms
Polyphenolic compounds
66 Citations (Scopus)

A γ-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice

Ju, J., Hao, X., Lee, M. J., Lambert, J. D., Lu, G., Xiao, H., Newmark, H. L. & Yang, C. S., Feb 1 2009, In : Cancer Prevention Research. 2, 2, p. 143-152 10 p.

Research output: Contribution to journalArticle

Azoxymethane
Dextran Sulfate
Tocopherols
Colon
Carcinogenesis
31 Citations (Scopus)

Inhibition of lung cancer growth in mice by dietary mixed tocopherols

Lambert, J. D., Lu, G., Lee, M. J., Hu, J., Ju, J. & Yang, C. S., Aug 1 2009, In : Molecular Nutrition and Food Research. 53, 8, p. 1030-1035 6 p.

Research output: Contribution to journalArticle

Tocopherols
lung neoplasms
tocopherols
Lung Neoplasms
mice
16 Citations (Scopus)

Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid

Meyers, R. O., Lambert, J. D., Hajicek, N., Pourpak, A., Kalaitzis, J. A. & Dorr, R. T., Aug 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4752-4755 4 p.

Research output: Contribution to journalArticle

Masoprocol
Carbonates
Cytotoxicity
Heterografts
Sulfates

Tea and Its Constituents

Lambert, J. D., Yang, C. S., Gelderblom, W. C. A., Gamieldien, K. & Joubert, E., Jul 16 2009, Chemoprevention of Cancer and DNA Damage by Dietary Factors. Wiley - VCH Verlag GmbH & CO. KGaA, p. 595-633 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tea
Biotransformation
Mutagenesis
Biological Availability
Reactive Oxygen Species
2008
196 Citations (Scopus)

Bioavailability issues in studying the health effects of plant polyphenolic compounds

Yang, C. S., Sang, S., Lambert, J. D. & Lee, M. J., Jun 1 2008, In : Molecular Nutrition and Food Research. 52, SUPPL. 1

Research output: Contribution to journalReview article

Polyphenols
Biological Availability
bioavailability
polyphenols
Health
54 Citations (Scopus)

Cancer prevention by tea and tea polyphenols

Yang, C. S., Ju, J., Lu, G., Xiao, H., Hao, X., Sang, S. & Lambert, J. D., Jan 1 2008, In : Asia Pacific Journal of Clinical Nutrition. 17, SUPPL. 1, p. 245-248 4 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
Neoplasms
Carcinogenesis
Pancrelipase
45 Citations (Scopus)

Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate

Lambert, J. D., Kwon, S. J., Ju, J., Bose, M., Lee, M. J., Hong, J., Hao, X. & Yang, C. S., Oct 13 2008, In : Carcinogenesis. 29, 10, p. 2019-2024 6 p.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Genistein
Biological Availability
Small Intestine
Neoplasms
21 Citations (Scopus)

N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct

Lambert, J. D., Sang, S. & Yang, C. S., Mar 15 2008, In : Free Radical Biology and Medicine. 44, 6, p. 1069-1074 6 p.

Research output: Contribution to journalArticle

Acetylcysteine
Lung Neoplasms
Cells
Cell culture
epigallocatechin gallate
23 Citations (Scopus)

Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds

Yang, C. S., Fang, M., Lambert, J. D., Yan, P. & Huang, T. H. M., Aug 1 2008, In : Nutrition reviews. 66, SUPPL.1

Research output: Contribution to journalArticle

DNA Modification Methylases
Genetic Epigenesis
Catechin
Phenols
Enzyme Inhibitors
377 Citations (Scopus)

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice

Bose, M., Lambert, J. D., Ju, J., Reuhl, K. R., Shapses, S. A. & Yang, C. S., Sep 1 2008, In : Journal of Nutrition. 138, 9, p. 1677-1683 7 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
Fatty Liver
Liver Diseases
Obesity
2007
154 Citations (Scopus)

Biotransformation of green tea polyphenols and the biological activities of those metabolites

Lambert, J. D., Sang, S. & Yang, C. S., Nov 1 2007, In : Molecular Pharmaceutics. 4, 6, p. 819-825 7 p.

Research output: Contribution to journalReview article

Theaceae
Camellia sinensis
Polyphenols
Biotransformation
Catechin
110 Citations (Scopus)

Inhibition of carcinogenesis by tea constituents

Ju, J., Lu, G., Lambert, J. D. & Yang, C. S., Oct 1 2007, In : Seminars in Cancer Biology. 17, 5, p. 395-402 8 p.

Research output: Contribution to journalReview article

Tea
Carcinogenesis
Neoplasms
Animal Models
Catechin
36 Citations (Scopus)

Inhibition of intestinal tumorigenesis in ApcMin/+ mice by green tea polyphenols (Polyphenon E) and individual catechins

Hao, X., Bose, M., Lambert, J. D., Ju, J., Lu, G., Lee, M. J., Park, S., Husain, A., Wang, S., Sun, Y. & Yang, C. S., Jan 1 2007, In : Nutrition and cancer. 59, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

Catechin
Polyphenols
Tea
Carcinogenesis
Drinking
35 Citations (Scopus)

Inhibition of tumorigenesis in ApcMin/+ mice by a combination of (-)-epigallocatechin-3-gallate and fish oil

Bose, M., Hao, X., Ju, J., Husain, A., Park, S., Lambert, J. D. & Yang, C. S., Sep 19 2007, In : Journal of agricultural and food chemistry. 55, 19, p. 7695-7700 6 p.

Research output: Contribution to journalArticle

Fish Oils
epigallocatechin
fish oils
carcinogenesis
Carcinogenesis
54 Citations (Scopus)

Metabolism of dietary polyphenols and possible interactions with drugs

Lambert, J. D., Sang, S., Lu, A. Y. H. & Yang, C. S., Jun 1 2007, In : Current Drug Metabolism. 8, 5, p. 499-507 9 p.

Research output: Contribution to journalReview article

Polyphenols
Drug Interactions
Metabolism
Pharmaceutical Preparations
Polyphenolic compounds
159 Citations (Scopus)

Possible controversy over dietary polyphenols: Benefits vs risks

Lambert, J. D., Sang, S. & Yang, C. S., Apr 1 2007, In : Chemical research in toxicology. 20, 4, p. 583-585 3 p.

Research output: Contribution to journalShort survey

Phenols
Polyphenols
Tea
Flavonoids
Gastrointestinal Tract
29 Citations (Scopus)

Salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity

Lambert, J. D., Kwon, S. J., Hong, J. & Yang, C. S., Jul 4 2007, In : Free Radical Research. 41, 7, p. 850-853 4 p.

Research output: Contribution to journalArticle

Mastication
Tea
Hydrogen Peroxide
Mouth
Catechin
196 Citations (Scopus)

Tea and cancer prevention: Molecular mechanisms and human relevance

Yang, C. S., Lambert, J. D., Ju, J., Lu, G. & Sang, S., Nov 1 2007, In : Toxicology and Applied Pharmacology. 224, 3, p. 265-273 9 p.

Research output: Contribution to journalReview article

Tea
Neoplasms
Animals
Polyphenols
Animal Models
2006
4 Citations (Scopus)

Bioavailabilities of tea polyphenols in humans and rodents

Lambert, J. D., Hong, J., Lu, H., Meng, X., Lee, M. J. & Yang, C. S., Sep 29 2006, Protective Effects of Tea on Human Health. CABI Publishing, p. 25-33 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Tea
tea
Biological Availability
bioavailability
29 Citations (Scopus)

Bioavailability and stability issues in understanding the cancer preventive effects of tea polyphenols

Sang, S., Lambert, J. D. & Yang, C. S., Nov 1 2006, In : Journal of the science of food and agriculture. 86, 14, p. 2256-2265 10 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
tea
Biological Availability
bioavailability
99 Citations (Scopus)

Dose-dependent levels of epigallocatechin-3-gallate in human colon cancer cells and mouse plasma and tissues

Lambert, J. D., Lee, M. J., Diamond, L., Ju, J., Hong, J., Bose, M., Newmark, H. L. & Yang, C. S., Jan 1 2006, In : Drug Metabolism and Disposition. 34, 1, p. 8-11 4 p.

Research output: Contribution to journalArticle

Theaceae
Plasma Cells
Camellia sinensis
Colonic Neoplasms
Small Intestine

Green Tea

Landau, J. M., Lambert, J. D. & Yang, C. S., Dec 1 2006, Nutritional Oncology. Elsevier Inc., p. 597-606 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tea
127 Citations (Scopus)

Molecular targets for the cancer preventive activity of tea polyphenols

Yang, C. S., Lambert, J. D., Hou, Z., Ju, J., Lu, G. & Hao, X., Jun 1 2006, In : Molecular Carcinogenesis. 45, 6, p. 431-435 5 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
Neoplasms
Animal Models
Cell Culture Techniques
109 Citations (Scopus)

Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate

Lambert, J. D., Sang, S., Hong, J., Kwon, S. J., Lee, M. J., Ho, C. T. & Yang, C. S., Dec 1 2006, In : Drug Metabolism and Disposition. 34, 12, p. 2111-2116 6 p.

Research output: Contribution to journalArticle

Biological Availability
In Vitro Techniques
epigallocatechin gallate
Camellia sinensis
HCT116 Cells
82 Citations (Scopus)

Possible mechanisms of the cancer-preventive activities of green tea

Yang, C. S., Sang, S., Lambert, J. D., Hou, Z., Ju, J. & Lu, G., Feb 1 2006, In : Molecular Nutrition and Food Research. 50, 2, p. 170-175 6 p.

Research output: Contribution to journalReview article

epigallocatechin
green tea
Tea
tea
neoplasms
34 Citations (Scopus)

Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice

Lambert, J. D., Kim, D. H., Zheng, R. & Yang, C. S., May 1 2006, In : Journal of Pharmacy and Pharmacology. 58, 5, p. 599-604 6 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
epigallocatechin gallate
Camellia sinensis
Catechin
30 Citations (Scopus)

Wheat bran oil and its fractions inhibit human colon cancer cell growth and intestinal tumorigenesis in Apcmin/+ mice

Sang, S., Ju, J., Lambert, J. D., Lin, Y., Hong, J., Bose, M., Wang, S., Bai, N., He, K., Reddy, B. S., Ho, C. T., Li, F. & Yang, C. S., Dec 27 2006, In : Journal of agricultural and food chemistry. 54, 26, p. 9792-9797 6 p.

Research output: Contribution to journalArticle

Dietary Fiber
Cell growth
wheat bran
colorectal neoplasms
Colonic Neoplasms
2005
7 Citations (Scopus)

Benzotropolone inhibitors of estradiol methylation: Kinetics and in silico modeling studies

Lambert, J. D., Chen, D., Wang, C. Y., Ai, N., Sang, S., Ho, C. T., Welsh, W. J. & Yang, C. S., Apr 1 2005, In : Bioorganic and Medicinal Chemistry. 13, 7, p. 2501-2507 7 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Methylation
Computer Simulation
Estradiol
Kinetics
5 Citations (Scopus)

Cancer prevention by tea and tea constituents

Landau, J. M., Lambert, J. D., Lee, M. J. & Yang, C., Jan 1 2005, Carcinogenic and Anticarcinogenic Food Components. CRC Press, p. 219-237 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

tea (beverage)
Tea
neoplasms
Neoplasms
leaves
17 Citations (Scopus)

Cytotoxic lignans from Larrea tridentata

Lambert, J. D., Sang, S., Dougherty, A., Caldwell, C. G., Meyers, R. O., Dorr, R. T. & Timmermann, B. N., Jan 1 2005, In : Phytochemistry. 66, 7, p. 811-815 5 p.

Research output: Contribution to journalArticle

Larrea
Larrea tridentata
Lignans
lignans
Colonic Neoplasms
373 Citations (Scopus)

Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.

Lambert, J. D., Hong, J., Yang, G. Y., Liao, J. & Yang, C. S., Jan 1 2005, In : The American journal of clinical nutrition. 81, 1 Suppl

Research output: Contribution to journalReview article

Polyphenols
Carcinogenesis
Tea
Curcumin
Biological Availability
106 Citations (Scopus)

Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: Structure-activity relationship and molecular-modeling studies

Chen, D., Wang, C. Y., Lambert, J. D., Ai, N., Welsh, W. J. & Yang, C. S., May 15 2005, In : Biochemical Pharmacology. 69, 10, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Molecular modeling
Catechin
Tea
Structure-Activity Relationship
99 Citations (Scopus)

Redox properties of tea polyphenols and related biological activities

Sang, S., Hou, Z., Lambert, J. D. & Yang, C. S., Nov 1 2005, In : Antioxidants and Redox Signaling. 7, 11-12, p. 1704-1714 11 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
Bioactivity
Oxidation-Reduction
Cell culture
76 Citations (Scopus)

Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives

Lambert, J. D., Rice, J. E., Hong, J., Hou, Z. & Yang, C. S., Feb 15 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 873-876 4 p.

Research output: Contribution to journalArticle

Catechin
Polyphenols
Tea
Metabolites
Bioactivity
75 Citations (Scopus)

Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice

Sang, S., Lambert, J. D., Hong, J., Tian, S., Lee, M. J., Stark, R. E., Ho, C. T. & Yang, C. S., Nov 1 2005, In : Chemical research in toxicology. 18, 11, p. 1762-1769 8 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Glutathione
Urine
Tea
epigallocatechin gallate
2004
4 Citations (Scopus)

Cancer Chemoprevention by Targeting Proteasomal Degradation

Yang, C. S., Chin, K. V. & Lambert, J. D., Apr 1 2004, In : Clinical Cancer Research. 10, 7, p. 2220-2221 2 p.

Research output: Contribution to journalComment/debate

Anticarcinogenic Agents
Cyclin E
Biological Models
Retinoblastoma Protein
Retinoic Acid Receptors
97 Citations (Scopus)

Delivery of Tea Polyphenols to the Oral Cavity by Green Tea Leaves and Black Tea Extract

Lee, M. J., Lambert, J. D., Prabhu, S., Meng, X., Lu, H., Maliakal, P., Ho, C. T. & Yang, C. S., Jan 1 2004, In : Cancer Epidemiology Biomarkers and Prevention. 13, 1, p. 132-137 6 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
Catechin
Mouth
Mouth Neoplasms
127 Citations (Scopus)

Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention

Hou, Z., Lambert, J. D., Chin, K. V. & Yang, C. S., Nov 2 2004, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 555, 1-2 SPEC. ISS., p. 3-19 17 p.

Research output: Contribution to journalReview article

Chemoprevention
Polyphenols
Tea
Signal Transduction
Carcinogenesis