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Research Output 2001 2020

Article
Tea
Liver
Fats
Nuclear Respiratory Factor 1
Sirtuin 1
127 Citations (Scopus)

Molecular targets for the cancer preventive activity of tea polyphenols

Yang, C. S., Lambert, J. D., Hou, Z., Ju, J., Lu, G. & Hao, X., Jun 1 2006, In : Molecular Carcinogenesis. 45, 6, p. 431-435 5 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
Neoplasms
Animal Models
Cell Culture Techniques
21 Citations (Scopus)

N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct

Lambert, J. D., Sang, S. & Yang, C. S., Mar 15 2008, In : Free Radical Biology and Medicine. 44, 6, p. 1069-1074 6 p.

Research output: Contribution to journalArticle

Acetylcysteine
Lung Neoplasms
Cells
Cell culture
epigallocatechin gallate
60 Citations (Scopus)

Nordihydroguaiaretic acid: Hepatotoxicity and detoxification in the mouse

Lambert, J. D., Zhao, D., Meyers, R. O., Kuester, R. K., Timmermann, B. N. & Dorr, R. T., Dec 1 2002, In : Toxicon. 40, 12, p. 1701-1708 8 p.

Research output: Contribution to journalArticle

Masoprocol
Detoxification
Larrea
Acids
Metabolism
109 Citations (Scopus)

Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate

Lambert, J. D., Sang, S., Hong, J., Kwon, S. J., Lee, M. J., Ho, C. T. & Yang, C. S., Dec 1 2006, In : Drug Metabolism and Disposition. 34, 12, p. 2111-2116 6 p.

Research output: Contribution to journalArticle

Biological Availability
In Vitro Techniques
epigallocatechin gallate
Camellia sinensis
HCT116 Cells
1 Citation (Scopus)

Perseorangin: A natural pigment from avocado (Persea americana) seed

Hatzakis, E., Mazzola, E. P., Shegog, R. M., Ziegler, G. R. & Lambert, J. D., Sep 30 2019, In : Food Chemistry. 293, p. 15-22 8 p.

Research output: Contribution to journalArticle

Persea
Persea americana
avocados
Pigments
seed extracts
16 Citations (Scopus)

Pharmacokinetic analysis by high-performance liquid chromatography of intravenous nordihydroguaiaretic acid in the mouse

Lambert, J. D., Meyers, R. O., Timmermann, B. N. & Dorr, R. T., Apr 15 2001, In : Journal of Chromatography B: Biomedical Sciences and Applications. 754, 1, p. 85-90 6 p.

Research output: Contribution to journalArticle

Masoprocol
Pharmacokinetics
High performance liquid chromatography
Plasmas
Arachidonate 5-Lipoxygenase
159 Citations (Scopus)

Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice

Lambert, J. D., Hong, J., Kim, D. H., Mishin, V. M. & Yang, C. S., Aug 1 2004, In : Journal of Nutrition. 134, 8, p. 1948-1952 5 p.

Research output: Contribution to journalArticle

piperine
Polyphenols
Tea
Biological Availability
epigallocatechin gallate
9 Citations (Scopus)

Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice

James, K. D., Kennett, M. J. & Lambert, J. D., Jan 1 2018, In : Food and Chemical Toxicology. 111, p. 302-309 8 p.

Research output: Contribution to journalArticle

Mitochondria
epigallocatechin
mitochondria
green tea
Tea
8 Citations (Scopus)

Prevention of hepatitis C virus infection using a broad cross-neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate

O'Shea, D., Law, J., Egli, A., Douglas, D., Lund, G., Forester, S., Lambert, J., Law, M., Burton, D. R., Tyrrell, D. L. J., Houghton, M., Humar, A. & Kneteman, N., Mar 1 2016, In : Liver Transplantation. 22, 3, p. 324-332 9 p.

Research output: Contribution to journalArticle

Virus Diseases
Neutralizing Antibodies
Hepacivirus
Monoclonal Antibodies
epigallocatechin gallate
23 Citations (Scopus)

Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds

Yang, C. S., Fang, M., Lambert, J. D., Yan, P. & Huang, T. H. M., Aug 1 2008, In : Nutrition reviews. 66, SUPPL.1, p. S18-S20

Research output: Contribution to journalArticle

DNA Modification Methylases
Genetic Epigenesis
Catechin
Phenols
Enzyme Inhibitors

Role of reactive oxygen species from the green tea catechin, (−)-epigallocatechin-3-gallate in growth modulation of intestinal cells

Kwon, S. J., Lambert, J. D., Yang, C. S. & Hong, J., Aug 3 2015, In : Food Science and Biotechnology. 24, 4, p. 1541-1548 8 p.

Research output: Contribution to journalArticle

Catechin
epigallocatechin
green tea
Tea
catechin
29 Citations (Scopus)

Salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity

Lambert, J. D., Kwon, S. J., Hong, J. & Yang, C. S., Jul 4 2007, In : Free Radical Research. 41, 7, p. 850-853 4 p.

Research output: Contribution to journalArticle

Mastication
Tea
Hydrogen Peroxide
Mouth
Catechin
12 Citations (Scopus)
Dietary Carbohydrates
Hep G2 Cells
Lipids
Carbohydrates
Liver
5 Citations (Scopus)

Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo

Bitzer, Z. T., Wopperer, A. L., Chrisfield, B. J., Tao, L., Cooper, T., Vanamala, J. K. P., Elias, R., Hayes, J. E. & Lambert, J. D., Feb 1 2017, In : Journal of Nutritional Biochemistry. 40, p. 201-208 8 p.

Research output: Contribution to journalArticle

Soybean Proteins
Dextran Sulfate
Inflammation
Caspase 1
Splenomegaly
18 Citations (Scopus)
Lung Neoplasms
Cell Line
Inhibitory Concentration 50
Catechol O-Methyltransferase
Growth
16 Citations (Scopus)

Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid

Meyers, R. O., Lambert, J. D., Hajicek, N., Pourpak, A., Kalaitzis, J. A. & Dorr, R. T., Aug 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4752-4755 4 p.

Research output: Contribution to journalArticle

Masoprocol
Carbonates
Cytotoxicity
Heterografts
Sulfates
76 Citations (Scopus)

Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives

Lambert, J. D., Rice, J. E., Hong, J., Hou, Z. & Yang, C. S., Feb 15 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 873-876 4 p.

Research output: Contribution to journalArticle

Catechin
Polyphenols
Tea
Metabolites
Bioactivity
75 Citations (Scopus)

Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice

Sang, S., Lambert, J. D., Hong, J., Tian, S., Lee, M. J., Stark, R. E., Ho, C. T. & Yang, C. S., Nov 1 2005, In : Chemical research in toxicology. 18, 11, p. 1762-1769 8 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Glutathione
Urine
Tea
epigallocatechin gallate
46 Citations (Scopus)

Tea consumption is inversely associated with weight status and other markers for metabolic syndrome in US adults

Vernarelli, J. A. & Lambert, J. D., Apr 1 2013, In : European Journal of Nutrition. 52, 3, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

Tea
Weights and Measures
Waist Circumference
Energy Intake
Camellia sinensis
52 Citations (Scopus)

tetra-O-Methylnordihydroguaiaretic acid inhibits melanoma in vivo

Lambert, J. D., Meyers, R. O., Timmermann, B. N. & Dorr, R. T., Aug 28 2001, In : Cancer Letters. 171, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

Masoprocol
Melanoma
Lignans
G2 Phase
Growth
37 Citations (Scopus)

The cancer preventive effects of edible mushrooms

Xu, T., Beelman, R. B. & Lambert, J. D., Dec 3 2012, In : Anti-Cancer Agents in Medicinal Chemistry. 12, 10, p. 1255-1263 9 p.

Research output: Contribution to journalArticle

Agaricales
Grifola
Shiitake Mushrooms
Reishi
Pleurotus
7 Citations (Scopus)
catechol O-methyltransferase
epigallocatechin
Biological Availability
bioavailability
mice
221 Citations (Scopus)

The chemistry and biotransformation of tea constituents

Sang, S., Lambert, J. D., Ho, C. T. & Yang, C. S., Jan 1 2011, In : Pharmacological Research. 64, 2, p. 87-99 13 p.

Research output: Contribution to journalArticle

Tea
Biotransformation
Catechin
Insurance Benefits
Theaceae
384 Citations (Scopus)

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice

Bose, M., Lambert, J. D., Ju, J., Reuhl, K. R., Shapses, S. A. & Yang, C. S., Sep 1 2008, In : Journal of Nutrition. 138, 9, p. 1677-1683 7 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
Fatty Liver
Liver Diseases
Obesity
42 Citations (Scopus)
Catechin
epigallocatechin
green tea
Tea
catechin
34 Citations (Scopus)

Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice

Lambert, J. D., Kim, D. H., Zheng, R. & Yang, C. S., May 1 2006, In : Journal of Pharmacy and Pharmacology. 58, 5, p. 599-604 6 p.

Research output: Contribution to journalArticle

Polyphenols
Tea
epigallocatechin gallate
Camellia sinensis
Catechin

Vitamin-supplemented chewing gum can increase salivary and plasma levels of a panel of vitamins in healthy human participants

Khoo, W. Y., Chrisfield, B. J., Colantonio, A. J. & Lambert, J. D., Nov 1 2018, In : Journal of Functional Foods. 50, p. 37-44 8 p.

Research output: Contribution to journalArticle

chewing gum
Chewing Gum
Vitamins
vitamins
Healthy Volunteers
12 Citations (Scopus)
metabolic syndrome
green tea
Tea
exercise
Fats
30 Citations (Scopus)

Wheat bran oil and its fractions inhibit human colon cancer cell growth and intestinal tumorigenesis in Apcmin/+ mice

Sang, S., Ju, J., Lambert, J. D., Lin, Y., Hong, J., Bose, M., Wang, S., Bai, N., He, K., Reddy, B. S., Ho, C. T., Li, F. & Yang, C. S., Dec 27 2006, In : Journal of agricultural and food chemistry. 54, 26, p. 9792-9797 6 p.

Research output: Contribution to journalArticle

Dietary Fiber
Cell growth
wheat bran
colorectal neoplasms
Colonic Neoplasms
Chapter
2 Citations (Scopus)

Antioxidant and Pro-Oxidant Activities of Green Tea Polyphenols in Cancer Prevention

Tao, L. & Lambert, J. D., Nov 1 2013, Polyphenols in Human Health and Disease. Elsevier Inc., Vol. 2. p. 1191-1198 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Tea
Reactive Oxygen Species
Antioxidants
Oxidation-Reduction
4 Citations (Scopus)

Bioavailabilities of tea polyphenols in humans and rodents

Lambert, J. D., Hong, J., Lu, H., Meng, X., Lee, M. J. & Yang, C. S., Sep 29 2006, Protective Effects of Tea on Human Health. CABI Publishing, p. 25-33 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Tea
tea
Biological Availability
bioavailability
5 Citations (Scopus)

Cancer prevention by tea and tea constituents

Landau, J. M., Lambert, J. D., Lee, M. J. & Yang, C., Jan 1 2005, Carcinogenic and Anticarcinogenic Food Components. CRC Press, p. 219-237 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

tea (beverage)
Tea
neoplasms
Neoplasms
leaves
7 Citations (Scopus)

Cancer Preventive Effects of Green Tea Polyphenols

Forester, S. C. & Lambert, J. D., Nov 1 2013, Polyphenols in Human Health and Disease. Elsevier Inc., Vol. 2. p. 1309-1322 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Tea
Neoplasms
Biological Availability
Breast Neoplasms

Green Tea

Landau, J. M., Lambert, J. D. & Yang, C. S., Dec 1 2006, Nutritional Oncology. Elsevier Inc., p. 597-606 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tea
5 Citations (Scopus)

Green tea polyphenols

Sang, S., Lambert, J. D., Ho, C. T. & Yang, C. S., Jan 1 2004, Encyclopedia of Dietary Supplements. CRC Press, p. 327-336 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Tea
Cholesterol
Glucose
Drinking
2 Citations (Scopus)

Neuroprotective Properties of Dietary Polyphenols in Parkinson's Disease

Darvesh, A. S., Mcclure, M., Sadana, P., Paxos, C., Geldenhuys, W. J., Lambert, J. D., Haqqi, T. M. & Richardson, J. R., Jan 2 2017, Neuroprotective Effects of Phytochemicals in Neurological Disorders. wiley, p. 243-263 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polyphenols
Parkinson Disease
Dopaminergic Neurons
Tea
Curcuma

Tea and Its Constituents

Lambert, J. D., Yang, C. S., Gelderblom, W. C. A., Gamieldien, K. & Joubert, E., Jul 16 2009, Chemoprevention of Cancer and DNA Damage by Dietary Factors. Wiley - VCH Verlag GmbH & CO. KGaA, p. 595-633 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tea
Biotransformation
Mutagenesis
Biological Availability
Reactive Oxygen Species
Comment/debate
4 Citations (Scopus)

Cancer Chemoprevention by Targeting Proteasomal Degradation

Yang, C. S., Chin, K. V. & Lambert, J. D., Apr 1 2004, In : Clinical Cancer Research. 10, 7, p. 2220-2221 2 p.

Research output: Contribution to journalComment/debate

Anticarcinogenic Agents
Cyclin E
Biological Models
Retinoblastoma Protein
Retinoic Acid Receptors
Editorial

Cocoa and human health

Lambert, J. D., Jun 1 2013, In : Molecular Nutrition and Food Research. 57, 6, p. 933 1 p.

Research output: Contribution to journalEditorial

Cardiotonic Agents
Metabolomics
Cacao
metabolomics
Polyphenols
9 Citations (Scopus)

Research on tea and health

Yang, C. S. & Lambert, J. D., Aug 1 2011, In : Pharmacological Research. 64, 2, p. 85-86 2 p.

Research output: Contribution to journalEditorial

Tea
Health
Research
Letter
1 Citation (Scopus)
Review article
190 Citations (Scopus)

Antioxidative and anti-carcinogenic activities of tea polyphenols

Yang, C. S., Lambert, J. D. & Sang, S., Jan 1 2009, In : Archives of Toxicology. 83, 1, p. 11-21 11 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
Camellia sinensis
Neoplasms
Polyphenolic compounds
34 Citations (Scopus)

Avocado (Persea americana) seed as a source of bioactive phytochemicals

Dabas, D., Shegog, R. M., Ziegler, G. R. & Lambert, J. D., Nov 25 2013, In : Current Pharmaceutical Design. 19, 34, p. 6133-6140 8 p.

Research output: Contribution to journalReview article

Persea
Phytochemicals
Seeds
Health
Lauraceae
31 Citations (Scopus)

Bioavailability and stability issues in understanding the cancer preventive effects of tea polyphenols

Sang, S., Lambert, J. D. & Yang, C. S., Nov 1 2006, In : Journal of the science of food and agriculture. 86, 14, p. 2256-2265 10 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
tea
Biological Availability
bioavailability
196 Citations (Scopus)

Bioavailability issues in studying the health effects of plant polyphenolic compounds

Yang, C. S., Sang, S., Lambert, J. D. & Lee, M. J., Jun 1 2008, In : Molecular Nutrition and Food Research. 52, SUPPL. 1, p. S139-S151

Research output: Contribution to journalReview article

Polyphenols
Biological Availability
bioavailability
polyphenols
Health
155 Citations (Scopus)

Biotransformation of green tea polyphenols and the biological activities of those metabolites

Lambert, J. D., Sang, S. & Yang, C. S., Nov 1 2007, In : Molecular Pharmaceutics. 4, 6, p. 819-825 7 p.

Research output: Contribution to journalReview article

Theaceae
Camellia sinensis
Polyphenols
Biotransformation
Catechin
54 Citations (Scopus)

Cancer prevention by tea and tea polyphenols

Yang, C. S., Ju, J., Lu, G., Xiao, H., Hao, X., Sang, S. & Lambert, J. D., Jan 1 2008, In : Asia Pacific Journal of Clinical Nutrition. 17, SUPPL. 1, p. 245-248 4 p.

Research output: Contribution to journalReview article

Polyphenols
Tea
Neoplasms
Carcinogenesis
Pancrelipase
128 Citations (Scopus)

Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention

Hou, Z., Lambert, J. D., Chin, K. V. & Yang, C. S., Nov 2 2004, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 555, 1-2 SPEC. ISS., p. 3-19 17 p.

Research output: Contribution to journalReview article

Chemoprevention
Polyphenols
Tea
Signal Transduction
Carcinogenesis
374 Citations (Scopus)

Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.

Lambert, J. D., Hong, J., Yang, G. Y., Liao, J. & Yang, C. S., Jan 1 2005, In : The American journal of clinical nutrition. 81, 1 Suppl

Research output: Contribution to journalReview article

Polyphenols
Carcinogenesis
Tea
Curcumin
Biological Availability