• 5002 Citations
  • 37 h-Index
1965 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 5002 Citations
  • 37 h-Index
  • 107 Article
  • 5 Review article
2020
Open Access
2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: The challenge ahead

Goodson, W. H., Lowe, L., Carpenter, D. O., Gilbertson, M., Ali, A. M., de Cerain Salsamendi, A. L., Lasfar, A., Carnero, A., Azqueta, A., Amedei, A., Charles, A. K., Collins, A. R., Ward, A., Salzberg, A. C., Colacci, A., Olsen, A. K., Berg, A., Barclay, B. J., Zhou, B. P., Blanco-Aparicio, C. & 153 others, Baglole, C. J., Dong, C., Mondello, C., Hsu, C. W., Naus, C. C., Yedjou, C., Curran, C. S., Laird, D. W., Koch, D. C., Carlin, D. J., Felsher, D. W., Roy, D., Brown, D. G., Ratovitski, E., Ryan, E. P., Corsini, E., Rojas, E., Moon, E. Y., Laconi, E., Marongiu, F., Al-Mulla, F., Chiaradonna, F., Darroudi, F., Martin, F. L., Van Schooten, F. J., Goldberg, G. S., Wagemaker, G., Nangami, G., Calaf, G. M., Williams, G., Wolf, G. T., Koppen, G., Brunborg, G., Kim Lyerly, H., Krishnan, H., Hamid, H. A., Yasaei, H., Sone, H., Kondoh, H., Salem, H. K., Hsu, H. Y., Park, H. H., Koturbash, I., Miousse, I. R., Ivana Scovassi, A., Klaunig, J. E., Vondráček, J., Raju, J., Roman, J., Wise, J. P., Whitfield, J. R., Woodrick, J., Christopher, J. A., Ochieng, J., Martinez-Leal, J. F., Weisz, J., Kravchenko, J., Sun, J., Prudhomme, K. R., Narayanan, K. B., Cohen-Solal, K. A., Moorwood, K., Gonzalez, L., Soucek, L., Jian, L., D'Abronzo, L. S., Lin, L. T., Li, L., Gulliver, L., McCawley, L. J., Memeo, L., Vermeulen, L., Leyns, L., Zhang, L., Valverde, M., Khatami, M., Romano, M. F., Chapellier, M., Williams, M. A., Wade, M., Manjili, M. H., Lleonart, M., Xia, M., Gonzalez, M. J., Karamouzis, M. V., Kirsch-Volders, M., Vaccari, M., Kuemmerle, N. B., Singh, N., Cruickshanks, N., Kleinstreuer, N., Van Larebeke, N., Ahmed, N., Ogunkua, O., Krishnakumar, P. K., Vadgama, P., Marignani, P. A., Ghosh, P. M., Ostrosky-Wegman, P., Thompson, P., Dent, P., Heneberg, P., Darbre, P., Leung, P. S., Nangia-Makker, P., Cheng, Q. S., Brooks Robey, R., Al-Temaimi, R., Roy, R., Andrade-Vieira, R., Sinha, R. K., Mehta, R., Vento, R., Di Fiore, R., Ponce-Cusi, R., Dornetshuber-Fleiss, R., Nahta, R., Castellino, R. C., Palorini, R., Hamid, R. A., Langie, S. A. S., Eltom, S., Brooks, S. A., Ryeom, S., Wise, S. S., Bay, S. N., Harris, S. A., Papagerakis, S., Romano, S., Pavanello, S., Eriksson, S., Forte, S., Casey, S. C., Luanpitpong, S., Lee, T. J., Otsuki, T., Chen, T., Massfelder, T., Sanderson, T., Guarnieri, T., Hultman, T., Dormoy, V., Odero-Marah, V., Sabbisetti, V., Maguer-Satta, V., Kimryn Rathmell, W., Engström, W., Decker, W. K., Bisson, W. H., Rojanasakul, Y., Luqmani, Y., Chen, Z. & Hu, Z., Jun 1 2015, In : Carcinogenesis. 36, p. S254-S296

Research output: Contribution to journalArticle

121 Scopus citations

Metabolic reprogramming and dysregulated metabolism: Cause, consequence and/or enabler of environmental carcinogenesis?

Brooks Robey, R., Weisz, J., Kuemmerle, N., Salzberg, A. C., Berg, A., Brown, D. G., Kubik, L., Palorini, R., Al-Mulla, F., Al-Temaimi, R., Colacci, A., Mondello, C., Raju, J., Woodrick, J., Ivana Scovassi, A., Singh, N., Vaccari, M., Roy, R., Forte, S., Memeo, L. & 10 others, Salem, H. K., Amedei, A., Hamid, R. A., Williams, G. P., Lowe, L., Meyer, J., Martin, F. L., Bisson, W. H., Chiaradonna, F. & Ryan, E. P., Jun 1 2015, In : Carcinogenesis. 36, p. S203-S231

Research output: Contribution to journalReview article

38 Scopus citations
2014

Infrared microspectroscopy identifies biomolecular changes associated with chronic oxidative stress in mammary epithelium and stroma of breast tissues from healthy young women: Implications for latent stages of breast carcinogenesis

Patel, I. I., Shearer, D. A., Fogarty, S. W., Fullwood, N. J., Quaroni, L., Martin, F. L. & Weisz, J., Feb 1 2014, In : Cancer Biology and Therapy. 15, 2, p. 225-235 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2012

Cyclic changes in the level of the innate immune molecule, surfactant protein-a, and cytokines in vaginal fluid

Macneill, C., de Guzman, G., Sousa, G. E., Umstead, T. M., Phelps, D., Floros, J., Ahn, K. & Weisz, J., Sep 1 2012, In : American Journal of Reproductive Immunology. 68, 3, p. 244-250 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Down-regulation of HtrA1 activates the Epithelial-Mesenchymal transition and ATM DNA damage response pathways

Wang, N., Eckert, K. A., Zomorrodi, A. R., Xin, P., Pan, W., Shearer, D. A., Weisz, J., Maranus, C. D. & Clawson, G. A., Jun 26 2012, In : PloS one. 7, 6, e39446.

Research output: Contribution to journalArticle

24 Scopus citations

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection

Durrani, F., Phelps, D., Weisz, J., Silveyra, P., Hu, S., Mikerov, A. N. & Floros, J., May 1 2012, In : Experimental Lung Research. 38, 4, p. 165-172 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
5 Scopus citations
2010

FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma

Mikse, O. R., Blake, D. C., Jones, N. R., Sun, Y. W., Amin, S., Gallagher, C. J., Lazarus, P., Weisz, J. & Herzog, C. R., Aug 1 2010, In : Cancer Research. 70, 15, p. 6205-6215 11 p.

Research output: Contribution to journalArticle

26 Scopus citations
2009

Altered gene expression in breast cancer liver metastases

Erin, N., Wang, N., Xin, P., Bui, V., Weisz, J., Barkan, G. A., Zhao, W., Shearer, D. & Clawson, G., Apr 1 2009, In : International Journal of Cancer. 124, 7, p. 1503-1516 14 p.

Research output: Contribution to journalArticle

39 Scopus citations
2008

Differentiation of xenografted human fetal lung parenchyma

Pavlovic, J., Floros, J., Phelps, D. S., Wigdahl, B., Welsh, P., Weisz, J., Shearer, D. A., Leure du Pree, A., Myers, R. & Howett, M. K., Mar 1 2008, In : Early Human Development. 84, 3, p. 181-193 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2005

A subset of in situ breast tumor cell clusters lacks expression of proliferation and progression related markers but shows signs of stromal and vascular invasion

Man, Y. G., Shen, T., Weisz, J., Berg, P. E., Schwartz, A. M., Mulshine, J. L., Sang, Q. X. A. & Nieburgs, H. E., Sep 16 2005, In : Cancer detection and prevention. 29, 4, p. 323-331 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2004

Surfactant protein A, an innate immune factor, is expressed in the vaginal mucosa and is present in vaginal lavage fluid

MacNeill, C., Umstead, T. M., Phelps, D. S., Lin, Z., Floros, J., Shearer, D. A. & Weisz, J., Jan 1 2004, In : Immunology. 111, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2003

Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: Implications for breast carcinogenesis

Triano, E. A., Slusher, L. B., Atkins, T. A., Beneski, J. T., Gestl, S. A., Zolfaghari, R., Polavarapu, R., Frauenhoffer, E. & Weisz, J., Jun 15 2003, In : Cancer Research. 63, 12, p. 3092-3100 9 p.

Research output: Contribution to journalArticle

54 Scopus citations
13 Scopus citations
2002

Expression of a retinol dehydrogenase (hRoDH-4), a member of the retinol/steroid dehydrogenase family implicated in retinoic acid biosynthesis, in normal and neoplastic endometria

Cain, J. M., Zaino, R., Shearer, D., Bennett, R. A., Olt, G. & Weisz, J., Jan 1 2002, In : American journal of obstetrics and gynecology. 186, 4, p. 675-683 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
45 Scopus citations
2001

Vitamin A: Recent advances in the biotransformation, transport, and metabolism of retinoids

Ross, A. C., Zolfaghari, R. & Weisz, J., 2001, In : Current Opinion in Gastroenterology. 17, 2, p. 184-192 9 p.

Research output: Contribution to journalReview article

56 Scopus citations
2000

Estrogen metabolism by conjugation.

Raftogianis, R., Creveling, C., Weinshilboum, R. & Weisz, J., Jan 1 2000, In : Journal of the National Cancer Institute. Monographs. 27, p. 113-124 12 p.

Research output: Contribution to journalReview article

213 Scopus citations

Nuclear localization of catechol-O-methyltransferase in neoplastic and nonneoplastic mammary epithelial cells

Weisz, J., Fritz-Wolz, G., Gestl, S., Clawson, G. A., Creveling, C. R., Liehr, J. G. & Dabbs, D., Jan 1 2000, In : American Journal of Pathology. 156, 6, p. 1841-1848 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Transformation of human vaginal xenografts by human papillomavirus type 11: Prevention of infection with a microbicide from the alkyl sulfate chemical family

Howett, M. K., Welsh, P. A., Budgeon, L. R., Ward, M. G., Neely, E. B., Patrick, S. D., Weisz, J. & Kreider, J. W., Jan 1 2000, In : Pathogenesis. 1, 4, p. 265-276 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
1999

An improved histochemical method for measuring nitric oxide synthase activity

Alaghband-Zadeh, J., Mehdizadeh, S., O'Farrell, A., Weisz, J., Bitensky, L. & Chayen, J., Sep 1 1999, In : Cell Biochemistry and Function. 17, 3, p. 217-220 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
1998

Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: Implications for estrogen-induced renal cancer

Weisz, J., Fritz-Wolz, G., Clawson, G., Benedict, C. M., Abendroth, C. & Creveling, C. R., Jul 1 1998, In : Carcinogenesis. 19, 7, p. 1307-1312 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
1997

Biogenesis and Inactivation of Catecholestrogens

Weisz, J., Clawson, G. A. & Creveling, C. R., 1997, In : Advances in Pharmacology. 42, C, p. 828-833 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Focal nuclear hepatocyte response to oxidative damage following low dose thioacetamide intoxication

Clawson, G. A., Benedict, C. M., Kelley, M. R. & Weisz, J., Aug 1 1997, In : Carcinogenesis. 18, 8, p. 1663-1668 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1996

Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers

Lu, Q., Nakmura, J., Savinov, A., Yue, W., Weisz, J., Dabbs, D. J., Wolz, G. & Brodie, A., Jan 1 1996, In : Endocrinology. 137, 7, p. 3061-3068 8 p.

Research output: Contribution to journalArticle

165 Scopus citations

Focal altered compartmentation of repetitive B2 (Alu-like) sequences in rat liver following hepatocarcinogen exposure

Clawson, G. A., Schalles, S. L., Wolz, G., Weisz, J., Crone, T. M. & Miranda, G. Q., Nov 7 1996, In : Cell Growth and Differentiation. 7, 5, p. 635-646 12 p.

Research output: Contribution to journalArticle

7 Scopus citations
1995

Histochemistry of guanylate cyclase activity

Mehdizadeh, S., O'Farrell, A., Bitensky, L., Weisz, J., Alaghband-Zadeh, J. & Chayen, J., Jan 1 1995, In : Journal of Histochemistry and Cytochemistry. 43, 12, p. 1235-1239 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Measurement of nitric oxide synthase activity in sections of rat liver

Mehdizadeh, S., O'Farrell, A., Bitensky, L., Weisz, J., Alaghband-Zadeh, J. & Chayen, J., Jan 1 1995, In : Journal of Histochemistry and Cytochemistry. 43, 12, p. 1229-1234 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
1994

Biogenesis of catecholestrogens: A mechanism for metabolic activation of estrogens.

Weisz, J., Jan 1994, In : Polycyclic Aromatic Compounds. 6, 1-4, p. 241-251 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: Implications for the mechanism of estrogen-induced carcinogenesis

Zhu, B. T., Bui, Q. D., Weisz, J. & Liehr, J. G., Jan 1 1994, In : Endocrinology. 135, 5, p. 1772-1779 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
1993

Central inhibition of nitric oxide synthase preferentially augments release of oxytocin during dehydration

Summy-Long, J. Y., Bui, V., Mantz, S., Koehler, E., Weisz, J. & Kadekaro, M., Apr 2 1993, In : Neuroscience Letters. 152, 1-2, p. 190-193 4 p.

Research output: Contribution to journalArticle

121 Scopus citations
1992

Elevated 4-hydroxylation of estradiol by hamster kidney microsomes: A potential pathway of metabolic activation of estrogens

Weisz, J., Bui, Q. D., Roy, D. & Liehr, J. G., Jan 1 1992, In : Endocrinology. 131, 2, p. 655-661 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Signals indicative of metabolic change in circumventricular organs

Summy-Long, J. Y., Kadekaro, M., Ng, Y. C. & Weisz, J., Jan 1 1992, In : Progress in Brain Research. 91, C, p. 235-246 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
1990

Effect of chronic estrogen treatment of syrian hamsters on microsomal enzymes mediating formation of catecholestrogens and their redox cycling: Implications for carcinogenesis

Liehr, J. G., Roy, D., Ari-Ulubelen, A., Bui, Q. D., Weisz, J. & Strobel, H. W., Apr 1990, In : Journal of Steroid Biochemistry. 35, 5, p. 555-560 6 p.

Research output: Contribution to journalArticle

44 Scopus citations
14 Scopus citations

Naltrexone normalizes the suppression but not the surge of Δ5-3β-hydroxysteroid dehydrogenase activity in leydig cells of stressed rat fetuses

Ward, I. L., Ward, O. B., Hayden, T., Weisz, J., Orth, J. M. & Ward, I. L., Jan 1 1990, In : Endocrinology. 127, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

The O6-methylation of 4-hydroxyestradiol is inhibited by 2-hydroxyestradiol: Implications for estrogen-induced carcinogenesis

Roy, D., Weisz, J. & Liehr, J. G., Mar 1 1990, In : Carcinogenesis. 11, 3, p. 459-462 4 p.

Research output: Contribution to journalArticle

60 Scopus citations
1989

Atrial natriuretic peptide in heart and specific binding in organs from fetal and newborn rats

Hersey, R. M., Nazir, M. A., Whitney, K. D., Klein, R. M., Sale, R. D., Hinton, D. A., Weisz, J. & Gattone, V. H., Jan 1989, In : Cell Biochemistry and Function. 7, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Comparison of assays for catechol estrogen synthase activity: Product isolation vs radioenzymatic catechol-O-methyltransferase-coupled procedures

Roy, D., Bui, Q. D., Weisz, J. & Liehr, J. G., Jan 1 1989, In : Journal of Steroid Biochemistry. 33, 2, p. 243-249 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Plasma luteinizing hormone levels in normal and prenatally stressed male and female rat fetuses and their mothers

Salisbury, R., Reed, J., Ward, I. L. & Weisz, J., Jan 1 1989, In : Biology of reproduction. 40, 1, p. 111-117 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
1988

Identification of microsomal, organic hydroperoxide-dependent catechol estrogen formation: Comparison with nadph-dependent mechanism

Bui, Q. & Weisz, J., Jan 1 1988, In : Pharmacology. 36, 5, p. 356-364 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Steroid structure and function. Molecular conformation of 4-hydroxyestradiol and its relation to other catechol estrogens

Wawrzak, Z., Duax, W. L., Strong, P. D. & Weisz, J., Apr 1988, In : Journal of Steroid Biochemistry. 29, 4, p. 387-392 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
1987
8 Scopus citations

Peroxidatic catecholestrogen production by human breast cancer tissue in vitro

Levin, M., Weisz, J., Bui, Q. D. & Santen, R. J., Nov 1987, In : Journal of Steroid Biochemistry. 28, 5, p. 513-520 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
1986

Catechol estrogen formation by the CNS: Regional distribution of estrogen-2/4-hydroxylase activity in rat brain

Weisz, J. & Crowley, W. R., Jan 1 1986, In : Neuroendocrinology. 43, 5, p. 543-549 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Catecholestrogen production by porcine ovarian cells

Hammond, J. M., Walega, M. A., Hersey, R. M. & Weisz, J., Jan 1 1986, In : Endocrinology. 118, 6, p. 2292-2299 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Purification and characterization of estrogen-2/4-hydroxylase activity from rabbit hypothalami: Peroxidase-mediated catechol estrogen formation

Mondschein, J. S., Hersey, R. M. & Weisz, J., Sep 1986, In : Endocrinology. 119, 3, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
1985

[Na‐K]ATPase activity in proximal and distal tubules of the rat kidney: Modification and application of a quantitative cytochemical technique

Hersey, R. M., Gattone, V. H. & Weisz, J., Oct 1985, In : Cell Biochemistry and Function. 3, 4, p. 255-265 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Catechol estrogen formation by pig blastocysts during the preimplantation period: Biochemical characterization of estrogen-2/4-hydroxylase and correlation with aromatase activity

Mondschein, J. S., Hersey, R. M., Dey, S. K., Davis, D. L. & Weisz, J., Jan 1 1985, In : Endocrinology. 117, 6, p. 2339-2346 8 p.

Research output: Contribution to journalArticle

51 Scopus citations