• 5651 Citations
  • 46 h-Index
1988 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
1988

Effect of excess dietary zinc on pancreatic exocrine function in the chick

Lu, J. & Combs, G. F., Jan 1 1988, In : Journal of Nutrition. 118, 6, p. 681-689 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Excess dietary zinc decreases tissue α-tocopherol in chicks

Lu, J. & Combs, G. F., Jan 1 1988, In : Journal of Nutrition. 118, 11, p. 1349-1359 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
1990

Time-course studies of pancreatic exocrine damage induced by excess dietary zinc in the chick

Lu, J., Combs, G. F. & Fleet, J. C., Jan 1 1990, In : Journal of Nutrition. 120, 4, p. 389-397 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
1992

Detergents inhibit chloramphenicol acetyl transferase

Lu, J. & Jiang, C., 1992, In : BioTechniques. 12, 5, p. 643-644 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Penicillamine: Pharmacokinetics and differential effects on zinc and copper status in chicks

Lu, J. & Combs, G. F., Jan 1 1992, In : Journal of Nutrition. 122, 2, p. 355-362 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
1993
1 Scopus citations

Spontaneous nucleosomal DNA fragmentation in murine leukemic L1210 cells

Jiang, C., Lu, J., Garcia, G. & Thompson, H. J., Jul 30 1993, In : Biochemical and Biophysical Research Communications. 194, 2, p. 836-841 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
1994

Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line

Thompson, H. J., Wilson, A., Lu, J., Singh, M., Jiang, C., Upadhyaya, P., El-bayoumy, K. & Ip, C., Feb 1 1994, In : Carcinogenesis. 15, 2, p. 183-186 4 p.

Research output: Contribution to journalArticle

138 Scopus citations

Effect of excess dietary iron on the promotion stage of 1-methyl-1- nitrosourea-induced mammary carcinogenesis: Pathogenetic characteristics and distribution of iron

Singh, M., Lu, J., Briggs, S. P., Mcginley, J. N., Haegele, A. D. & Thompson, H. J., Aug 1 1994, In : Carcinogenesis. 15, 8, p. 1567-1570 4 p.

Research output: Contribution to journalArticle

23 Scopus citations

Selenite induction of DNA strand breaks and apoptosis in mouse leukemic L1210 cells

Lu, J., Kaeck, M., Jiang, C., Wilson, A. C. & Thompson, H. J., Apr 29 1994, In : Biochemical Pharmacology. 47, 9, p. 1531-1535 5 p.

Research output: Contribution to journalArticle

129 Scopus citations

Start site selection by Sp1 in the TATA-less human Ha-ras promoter

Lu, J., Lee, W., Jiang, C. & Keller, E. B., Feb 18 1994, In : Journal of Biological Chemistry. 269, 7, p. 5391-5402 12 p.

Research output: Contribution to journalArticle

114 Scopus citations
1995

Cellular and metabolic effects of triphenylselenonium chloride in a mammary cell culture model

Lu, J., Jiang, C., Kaeck, M., Ganther, H., Ip, C. & Thompson, H., Mar 1 1995, In : Carcinogenesis. 16, 3, p. 513-517 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Dissociation of the genotoxic and growth inhibitory effects of selenium

Lu, J., Jiang, C., Kaeck, M., Ganther, H., Vadhanavikit, S., Clement, IP. P. & Thompson, H., Jul 17 1995, In : Biochemical Pharmacology. 50, 2, p. 213-219 7 p.

Research output: Contribution to journalArticle

126 Scopus citations

Ras May Mediate Mammary Cancer Promotion By High Fat

Lu, J., Jiang, C., Fontaine, S. & Thompson, H. J., Jan 1 1995, In : Nutrition and cancer. 23, 3, p. 283-290 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Sixty-nine kilobases of contiguous human genomic sequence containing the α-galactosidase A and Bruton's tyrosine kinase loci

Oeltjen, J. C., Liu, X., Lu, J., Allen, R. C., Muzny, D., Belmont, J. W. & Gibbs, R. A., May 1 1995, In : Mammalian Genome. 6, 5, p. 334-338 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
1996

A filter elution assay for the simultaneous detection of DNA double and single strand breaks

Lu, J., Kaeck, M. R., Jiang, C., Garcia, G. & Thompson, H. J., Mar 15 1996, In : Analytical Biochemistry. 235, 2, p. 227-233 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention

Lu, J., Pei, H., Ip, C., Lisk, D. J., Ganther, H. & Thompson, H. J., Sep 1996, In : Carcinogenesis. 17, 9, p. 1903-1907 5 p.

Research output: Contribution to journalArticle

94 Scopus citations

Method for 96-well M13 DNA template preparations for large-scale sequencing

Andersson, B., Lu, J., Edwards, K. E., Muzny, D. M. & Gibbs, R. A., 1996, In : BioTechniques. 20, 6, p. 1022-1027 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
1997

Differential induction of growth arrest inducible genes by selenium compounds

Kaeck, M., Lu, J., Strange, R., Ip, C., Ganther, H. E. & Thompson, H. J., Apr 4 1997, In : Biochemical Pharmacology. 53, 7, p. 921-926 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Gene expression changes associated with chemically induced rat mammary carcinogenesis

Lu, J., Pei, H., Kaeck, M. & Thompson, H. J., Oct 1 1997, In : Molecular Carcinogenesis. 20, 2, p. 204-215 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

Sulfone metabolite of sulindac inhibits mammary carcinogenesis

Thompson, H. J., Jiang, C., Lu, J., Mehta, R. G., Piazza, G. A., Paranka, N. S., Pamukcu, R. & Ahnen, D. J., Jan 28 1997, In : Cancer Research. 57, 2, p. 267-271 5 p.

Research output: Contribution to journalArticle

198 Scopus citations
1998

Pathogenetic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat

Lu, J., Jiang, C., Mitrenga, T., Cutter, G. & Thompson, H. J., Jan 1 1998, In : Carcinogenesis. 19, 1, p. 223-227 5 p.

Research output: Contribution to journalArticle

25 Scopus citations
1999

Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells

Sinha, R., Kiley, S. C., Lu, J. X., Thompson, H. J., Moraes, R., Jaken, S. & Medina, D., Nov 15 1999, In : Cancer Letters. 146, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Mammary cancer promotion and MAPK activation associated with consumption of a corn oil-based high-fat diet

Wang, Z., Pei, H., Kaeck, M. & Lu, J., Jan 1 1999, In : Nutrition and cancer. 34, 2, p. 140-146 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake

Jiang, C., Jiang, W., Ip, C., Ganther, H. & Lu, J., Dec 20 1999, In : Molecular Carcinogenesis. 26, 4, p. 213-225 13 p.

Research output: Contribution to journalArticle

176 Scopus citations
2000
97 Scopus citations

Monomethyl selenium-specific inhibition of MMP-2 and VEGF expression: Implications for angiogenic switch regulation

Jiang, C., Ganther, H. & Lu, J., Dec 1 2000, In : Molecular Carcinogenesis. 29, 4, p. 236-250 15 p.

Research output: Contribution to journalArticle

107 Scopus citations
2001
69 Scopus citations

Apoptosis and angiogenesis in cancer prevention by selenium

Lu, J., Aug 7 2001, In : Advances in Experimental Medicine and Biology. 492, p. 131-145 15 p.

Research output: Contribution to journalArticle

38 Scopus citations

Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells

Jiang, C., Wang, Z., Ganther, H. & Lu, J., Apr 1 2001, In : Cancer Research. 61, 7, p. 3062-3070 9 p.

Research output: Contribution to journalArticle

226 Scopus citations
2002

Biological and genetic properties of the p53 null preneoplastic mammary epithelium.

Medina, D., Kittrell, F. S., Shepard, A., Stephens, L. C., Jiang, C., Lu, J., Allred, D. C., McCarthy, M. & Ullrich, R. L., Jun 2002, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16, 8, p. 881-883 3 p.

Research output: Contribution to journalArticle

85 Scopus citations
138 Scopus citations

Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol

Wang, Z., Jiang, C. & Lu, J., Jul 20 2002, In : Molecular Carcinogenesis. 34, 3, p. 113-120 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Selenium compounds inhibit IκB kinase (IKK) and nuclear factor-κB (NF-κB) in prostate cancer cells

Gasparian, A. V., Yao, Y. J., Lu, J., Yemelyanov, A. Y., Lyakh, L. A., Slaga, T. J. & Budunova, I. V., Oct 1 2002, In : Molecular cancer therapeutics. 1, 12, p. 1079-1087 9 p.

Research output: Contribution to journalArticle

106 Scopus citations
2004

Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway

Jiang, C., Kim, K. H., Wang, Z. & Lü, J., Jan 1 2004, In : Nutrition and cancer. 49, 2, p. 174-183 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription

Cho, S. D., Jiang, C., Malewicz, B., Dong, Y., Young, C. Y. F., Kang, K. S., Lee, Y. S., Ip, C. & Lü, J., May 1 2004, In : Molecular cancer therapeutics. 3, 5, p. 605-611 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Selenite-induced p53 ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells

Jiang, C., Hu, H., Malewicz, B., Wang, Z. & Lü, J., Jul 1 2004, In : Molecular cancer therapeutics. 3, 7, p. 877-884 8 p.

Research output: Contribution to journalArticle

86 Scopus citations
2005

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells

Cho, S. D., Li, G., Hu, H., Jiang, C., Kang, K. S., Lee, Y. S., Kim, S. H. & Lu, J., Nov 16 2005, In : Nutrition and cancer. 52, 2, p. 213-224 12 p.

Research output: Contribution to journalArticle

96 Scopus citations

Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells

Hu, H., Jiang, C., Ip, C., Rustum, Y. M. & Lü, J., Mar 15 2005, In : Clinical Cancer Research. 11, 6, p. 2379-2388 10 p.

Research output: Contribution to journalArticle

68 Scopus citations

PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells

Hu, H., Jiang, C., Li, G. & Lü, J., Aug 1 2005, In : Carcinogenesis. 26, 8, p. 1374-1381 8 p.

Research output: Contribution to journalArticle

86 Scopus citations
2006

An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis

Lee, H. J., Lee, E. O., Rhee, Y. H., Ahn, K. S., Li, G. X., Jiang, C., Lü, J. & Kim, S. H., Dec 1 2006, In : Carcinogenesis. 27, 12, p. 2455-2463 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

Augmented suppression of androgen receptor signaling by a combination of α-tocopheryl succinate and methylseleninic acid

Zhang, H., Wu, Y., Malewicz, B., Lu, J., Li, S., Marshall, J., Ip, C. & Dong, Y., Dec 15 2006, In : Cancer. 107, 12, p. 2942-2948 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

Hu, H., Jiang, C., Schuster, T., Li, G. X., Daniel, P. T. & Lü, J., Jul 1 2006, In : Molecular cancer therapeutics. 5, 7, p. 1873-1882 10 p.

Research output: Contribution to journalArticle

83 Scopus citations

Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: Identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer

Jiang, C., Lee, H. J., Li, G. X., Guo, J., Malewicz, B., Zhao, Y., Lee, E. O., Lee, H. J., Lee, J. H., Kim, M. S., Kim, S. H. & Lu, J., Jan 1 2006, In : Cancer Research. 66, 1, p. 453-463 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities

Lee, E. O., Lee, H. J., Hwang, H. S., Ahn, K. S., Chae, C., Kang, K. S., Lu, J. & Kim, S. H., Oct 1 2006, In : Carcinogenesis. 27, 10, p. 2059-2069 11 p.

Research output: Contribution to journalArticle

73 Scopus citations
2007

6-(1-Oxobutyl)-5,8-dimethoxy-1,4-naphthoquinone inhibits Lewis lung cancer by antiangiogenesis and apoptosis

Hyo, J. L., Lee, H. J., Song, G. Y., Li, G., Lee, J. H., Lu, J. & Kim, S. H., Jun 1 2007, In : International Journal of Cancer. 120, 11, p. 2481-2490 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

A novel class of pyranocoumarin anti-androgen receptor signaling compounds

Guo, J., Jiang, C., Wang, Z., Lee, H. J., Hu, H., Malewicz, B., Lee, H. J., Lee, J. H., Baek, N. I., Jeong, J. H., Kim, D. K., Kang, K. S., Kim, S. H. & Lu, J., Mar 1 2007, In : Molecular cancer therapeutics. 6, 3, p. 907-917 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells

Jiang, C., Guo, J., Wang, Z., Xiao, B., Lee, H. J., Lee, E. O., Kim, S. H. & Lu, J., Nov 6 2007, In : Breast Cancer Research. 9, 6, R77.

Research output: Contribution to journalArticle

65 Scopus citations

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells

Li, G. X., Hu, H., Jiang, C., Schuster, T. & Lü, J., May 1 2007, In : International Journal of Cancer. 120, 9, p. 2034-2043 10 p.

Research output: Contribution to journalArticle

95 Scopus citations
2008

Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down-regulates antiapoptotic proteins Bcl-XL and survivin

Hu, H., Li, G. X., Wang, L., Watts, J., Combs, G. F. & Lü, J., Feb 15 2008, In : Clinical Cancer Research. 14, 4, p. 1150-1158 9 p.

Research output: Contribution to journalArticle

49 Scopus citations