Justin Pritchard

Assistant Professor, Biomedical Engineering
Huck Institutes of the Life Sciences
Penn State Cancer Institute
Cancer Institute, Mechanisms of Carcinogenesis

765 Citations
15 h-Index

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1 Similar Profiles

Neoplasms Medicine & Life Sciences

Pharmaceutical Preparations Medicine & Life Sciences

Drug Resistance Medicine & Life Sciences

Growth Medicine & Life Sciences

Drug Combinations Medicine & Life Sciences

Mycobacterium Medicine & Life Sciences

tanespimycin Medicine & Life Sciences

oxaliplatin Medicine & Life Sciences

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Research Output 2008 2019

765 Citations
15 h-Index
20 Article
1 Review article

Evolution of the nonsense-mediated decay pathway is associated with decreased cytolytic immune infiltration

Zhao, B. & Pritchard, J. R., Jan 1 2019, In : PLoS computational biology. 15, 10, e1007467.

Research output: Contribution to journal › Article

Open Access

Infiltration

tumor

Tumors

mutation

Pathway

16 Citations (Scopus)

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Laencina, L., Dubois, V., Le Moigne, V., Viljoen, A., Majlessi, L., Pritchard, J., Bernut, A., Piel, L., Roux, A. L., Gaillard, J. L., Lombard, B., Loew, D., Rubin, E. J., Brosch, R., Kremer, L., Herrmann, J. L. & Girard-Misguich, F., Jan 30 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. E1002-E1011

Research output: Contribution to journal › Article

Amoeba

Mycobacterium

Phagosomes

Growth

Genes

2 Citations (Scopus)

RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

Gozgit, J. M., Chen, T. H., Song, Y., Wardwell, S., Wang, F., Cai, J., Li, H., Edgren, H., Rivera, V. M. & Pritchard, J., Jul 1 2018, In : Oncotarget. 9, 51, p. 29654-29664 11 p.

Research output: Contribution to journal › Article

Transfection

Colorectal Neoplasms

Lung Neoplasms

Heterografts

Genomics

3 Citations (Scopus)

Single-molecule sequencing reveals patterns of preexisting drug resistance that suggest treatment strategies in Philadelphia-positive leukemias

Schmitt, M. W., Pritchard, J. R., Leighow, S. M., Aminov, B. I., Beppu, L., Kim, D. S., Hodgson, J. G., Rivera, V. M., Loeb, L. A. & Radich, J. P., Nov 1 2018, In : Clinical Cancer Research. 24, 21, p. 5321-5334 14 p.

Research output: Contribution to journal › Article

Drug Resistance

Leukemia

Mutation

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Pharmaceutical Preparations

95 Citations (Scopus)

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Bruno, P. M., Liu, Y., Park, G. Y., Murai, J., Koch, C. E., Eisen, T. J., Pritchard, J. R., Pommier, Y., Lippard, S. J. & Hemann, M. T., Apr 1 2017, In : Nature Medicine. 23, 4, p. 461-471 11 p.

Research output: Contribution to journal › Article

oxaliplatin

Platinum

Ribosomes

Cisplatin

Carboplatin