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Nucleotides Medicine & Life Sciences

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Projects 2015 2019

Nucleotide Metabolism in Senescence and Platinum Resistance of Ovarian Cancer

Aird, K.

National Institutes of Health


Project: Research projectResearch Transition Award, Career Transition Award

Ovarian Neoplasms
Neoplastic Stem Cells

Research Output 2004 2019

Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry

Kuskovsky, R., Buj, R., Xu, P., Hofbauer, S., Doan, M. T., Jiang, H., Bostwick, A., Mesaros, C., Aird, K. & Snyder, N. W., Mar 1 2019, In : Analytical Biochemistry. 568, p. 65-72 8 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography

CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer

Singha, B., Harper, S. L., Goldman, A. R., Bitler, B. G., Aird, K., Borowsky, M. E., Cadungog, M. G., Liu, Q., Zhang, R., Jean, S., Drapkin, R. & Speicher, D. W., Dec 1 2018, In : Scientific Reports. 8, 1, 14725.

Research output: Contribution to journalArticle

Staining and Labeling
Organ Culture Techniques
2 Citations

Deoxyribonucleotide triphosphate metabolism in cancer and metabolic disease

Buj, R. & Aird, K., Apr 18 2018, In : Frontiers in Endocrinology. 9, APR, 177.

Research output: Contribution to journalShort survey

Metabolic Diseases
Metabolic Networks and Pathways

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J., Timmins, P. F., Kesterson, J., Phaeton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. & Hempel, N., Jan 1 2018, (Accepted/In press) In : Redox Biology.

Research output: Contribution to journalArticle

Glutathione Peroxidase
Ovarian Neoplasms
23 Citations

ARID1A-mutated ovarian cancers depend on HDAC6 activity

Bitler, B. G., Wu, S., Park, P. H., Hai, Y., Aird, K., Wang, Y., Zhai, Y., Kossenkov, A. V., Vara-Ailor, A., Rauscher, F. J., Zou, W., Speicher, D. W., Huntsman, D. G., Conejo-Garcia, J. R., Cho, K. R., Christianson, D. W. & Zhang, R., Aug 1 2017, In : Nature Cell Biology. 19, 8, p. 962-973 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Chromatin Assembly and Disassembly