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Research Output 1984 2018

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Article
2018
4 Citations (Scopus)

Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish

Copper, J. E., Budgeon, L. R., Foutz, C. A., Van Rossum, D. B., Vanselow, D. J., Hubley, M. J., Clark, D. P., Mandrell, D. T. & Cheng, K., Jun 1 2018, In : Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology. 208, p. 38-46 9 p.

Research output: Contribution to journalArticle

Histological Techniques
Zebrafish
Tissue
Histology
Hydration
6 Citations (Scopus)

Dietary lipophilic iron alters amyloidogenesis and microglial morphology in Alzheimer's disease knock-in APP mice

Peters, D. G., Pollack, A. N., Cheng, K., Sun, D., Saido, T., Haaf, M. P., Yang, Q., Connor, J. & Meadowcroft, M., Mar 1 2018, In : Metallomics. 10, 3, p. 426-443 18 p.

Research output: Contribution to journalArticle

Dietary Iron
Alzheimer Disease
Iron
Brain
Amyloid

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography

Lin, A. Y., Ding, Y., Vanselow, D. J., Katz, S. R., Yakovlev, M. A., Clark, D. P., Mandrell, D., Copper, J. E., Van Rossum, D. B. & Cheng, K., Oct 17 2018, In : Journal of visualized experiments : JoVE. 140

Research output: Contribution to journalArticle

Histology
Tomography
Tissue
X rays
Immobilization
2013
9 Citations (Scopus)

Molecular phylogeography of a human autosomal skin color locus under natural selection

Canfield, V., Berg, A., Peckins, S., Wentzel, S. M., Ang, K., Oppenheimer, S. & Cheng, K., Jan 1 2013, In : G3: Genes, Genomes, Genetics. 3, 11, p. 2059-2067 9 p.

Research output: Contribution to journalArticle

Phylogeography
Skin Pigmentation
Genetic Selection
Haplotypes
Mutation
2012
9 Citations (Scopus)

Aquatic models, genomics and chemical risk management

Cheng, K., Hinton, D. E., Mattingly, C. J. & Planchart, A., Jan 1 2012, In : Comparative Biochemistry and Physiology - C Toxicology and Pharmacology. 155, 1, p. 169-173 5 p.

Research output: Contribution to journalArticle

Chemical Models
Risk Management
Genomics
Risk management
Animals
29 Citations (Scopus)

Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish

Tsetskhladze, Z. R., Canfield, V., Ang, K., Wentzel, S. M., Reid, K. P., Berg, A., Johnson, S. L., Kawakami, K. & Cheng, K., Oct 10 2012, In : PloS one. 7, 10, e47398.

Research output: Contribution to journalArticle

Functional assessment
Skin Pigmentation
Zebrafish
Polymorphism
Danio rerio
20 Citations (Scopus)

Skin color variation in Orang Asli tribes of Peninsular Malaysia

Ang, K., Ngu, M. S., Reid, K. P., Teh, M. S., Aida, Z. S., Koh, D. X. R., Berg, A., Oppenheimer, S., Salleh, H., Clyde, M. M., Md-Zain, B. M., Canfield, V. & Cheng, K., Aug 13 2012, In : PLoS One. 7, 8, e42752.

Research output: Contribution to journalArticle

Skin Pigmentation
tribal peoples
Malaysia
Population Groups
skin (animal)
2011
5 Citations (Scopus)

Genetic ancestry., skin reflectance and pigmentation genotypes in association with serum vitamin D metabolite balance

Wilson, R., Roff, A. N., Dai, P. J., Fortugno, T., Douds, J., Chen, G., Nikiforova, S. O., Chinchilli, V., Hartman, T. J., Demers, L., Canfield, V., Cheng, K., Grove, G. L., Barnholtz-Sloan, J., Frudakis, T., Shriver, M., Cheng, K. C. & Wilson, R. T., Jan 1 2011, In : Hormone Molecular Biology and Clinical Investigation. 7, 1, p. 279-293 15 p.

Research output: Contribution to journalArticle

Skin Pigmentation
Melanins
Vitamin D
Genotype
Serum
10 Citations (Scopus)

SHIRAZ: An automated histology image annotation system for Zebrafish phenomics

Canada, B. A., Thomas, G. K., Cheng, K. & Wang, J., Jan 1 2011, In : Multimedia Tools and Applications. 51, 2, p. 401-440 40 p.

Research output: Contribution to journalArticle

Histology
Genes
Image retrieval
2010
73 Citations (Scopus)

Predicting phenotype from genotype: Normal pigmentation

Valenzuela, R. K., Henderson, M. S., Walsh, M. H., Garrison, N. A., Kelch, J. T., Cohen-Barak, O., Erickson, D. T., John Meaney, F., Bruce Walsh, J., Cheng, K., Ito, S., Wakamatsu, K., Frudakis, T., Thomas, M. & Brilliant, M. H., Mar 1 2010, In : Journal of Forensic Sciences. 55, 2, p. 315-322 8 p.

Research output: Contribution to journalArticle

Pigmentation
Genotype
Phenotype
Single Nucleotide Polymorphism
Hair Color
2009
79 Citations (Scopus)

Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease

Zinnanti, W. J., Lazovic, J., Griffin, K., Skvorak, K. J., Paul, H. S., Homanics, G. E., Bewley, M., Cheng, K., Lanoue, K. F. & Flanagan, J., Apr 1 2009, In : Brain. 132, 4, p. 903-918 16 p.

Research output: Contribution to journalArticle

Maple Syrup Urine Disease
Brain Injuries
Branched Chain Amino Acids
Norleucine
Brain Diseases
2008
1 Citation (Scopus)

Research implications of pigment biology in zebrafish

Ekker, S. C., Parichy, D. M. & Cheng, K., Dec 1 2008, In : Zebrafish. 5, 4, p. 233-235 3 p.

Research output: Contribution to journalArticle

Biological Pigments
Zebrafish Proteins
gene expression regulation
Gene Expression Regulation
Zebrafish
2007
242 Citations (Scopus)

Genetic evidence for the convergent evolution of light skin in Europeans and East Asians

Norton, H. L., Kittles, R. A., Parra, E., McKeigue, P., Mao, X., Cheng, K., Canfield, V., Bradley, D. G., McEvoy, B. & Shriver, M., Mar 1 2007, In : Molecular biology and evolution. 24, 3, p. 710-722 13 p.

Research output: Contribution to journalArticle

convergent evolution
Pigmentation
skin (animal)
pigmentation
skin
73 Citations (Scopus)

Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I

Zinnanti, W. J., Lazovic, J., Housman, C., Lanoue, K., O'Callaghan, J. P., Simpson, I., Woontner, M., Goodman, S. I., Connor, J., Jacobs, R. E. & Cheng, K., Nov 1 2007, In : Journal of Clinical Investigation. 117, 11, p. 3258-3270 13 p.

Research output: Contribution to journalArticle

Brain Injuries
Lysine
Brain
Magnetic Resonance Spectroscopy
Corpus Striatum
2006
64 Citations (Scopus)

A diet-induced mouse model for glutaric aciduria type I

Zinnanti, W. J., Lazovic, J., Wolpert, E. B., Antonetti, D. A., Smith, M. B., Connor, J., Woontner, M., Goodman, S. I. & Cheng, K., Apr 1 2006, In : Brain. 129, 4, p. 899-910 12 p.

Research output: Contribution to journalArticle

Corpus Striatum
Lysine
Diet
Glutaryl-CoA Dehydrogenase
Dietary Proteins
68 Citations (Scopus)

High-throughput zebrafish histology

Sabaliauskas, N. A., Foutz, C. A., Mest, J. R., Budgeon, L. R., Sidor, A. T., Gershenson, J. A., Joshi, S. B. & Cheng, K., Jul 1 2006, In : Methods. 39, 3, p. 246-254 9 p.

Research output: Contribution to journalArticle

Histology
Zebrafish
Throughput
Phenotype
Reverse Genetics
126 Citations (Scopus)

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes

Chi, A., Valencia, J. C., Hu, Z. Z., Watabe, H., Yamaguchi, H., Mangini, N. J., Huang, H., Canfield, V., Cheng, K., Yang, F., Abe, R., Yamagishi, S., Shabanowitz, J., Hearing, V. J., Wu, C., Appella, E. & Hunt, D. F., Nov 1 2006, In : Journal of Proteome Research. 5, 11, p. 3135-3144 10 p.

Research output: Contribution to journalArticle

Melanosomes
Bioinformatics
Computational Biology
Proteomics
Melanins
1 Citation (Scopus)
Automated Pattern Recognition
Anatomic Models
Information Storage and Retrieval
Zebrafish
Computational Biology
28 Citations (Scopus)

Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish

Blasiole, B., Canfield, V., Vollrath, M. A., Huss, D., Mohideen, M. A. P. K., Dickman, J. D., Cheng, K., Fekete, D. M. & Levenson, R., Jun 1 2006, In : Developmental biology. 294, 1, p. 148-160 13 p.

Research output: Contribution to journalArticle

Otolithic Membrane
Semicircular Canals
Zebrafish
Genes
Ouabain
45 Citations (Scopus)

Zebrafish genomic instability mutants and cancer susceptibility

Moore, J. L., Rush, L. M., Breneman, C., Mohideen, M. A. P. K. & Cheng, K., Nov 6 2006, In : Genetics. 174, 2, p. 585-600 16 p.

Research output: Contribution to journalArticle

Genomic Instability
Zebrafish
Mutation
Neoplasms
Heterozygote
2005
31 Citations (Scopus)

Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids

Duffy, K. T., McAleer, M. F., Davidson, W. R., Kari, L., Kari, C., Liu, C. G., Farber, S. A., Cheng, K., Mest, J. R., Wickstrom, E., Dicker, A. P. & Rodeck, U., Oct 17 2005, In : Nucleic acids research. 33, 15, p. 4914-4921 8 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
cdc Genes
Morpholinos
Cyclin D1
Zebrafish
620 Citations (Scopus)

Genetics: SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

Lamason, R. L., Mohideen, M. A. P. K., Mest, J. R., Wong, A. C., Norton, H. L., Aros, M. C., Jurynec, M. J., Mao, X., Humphreville, V. R., Humbert, J. E., Sinha, S., Moore, J. L., Jagadeeswaran, P., Zhao, W., Ning, G., Makalowska, I., McKeigue, P. M., O'Donnell, D., Kittles, R., Parra, E. J. & 5 othersMangini, N. J., Grunwald, D. J., Shriver, M., Canfield, V. & Cheng, K., Dec 16 2005, In : Science. 310, 5755, p. 1782-1786 5 p.

Research output: Contribution to journalArticle

Pigmentation
Zebrafish
Cations
Melanosomes
Alleles
46 Citations (Scopus)

ptena and ptenb genes play distinct roles in zebrafish embryogenesis

Petko, J. A., Blasiole, B., Riddle, R. C., Thisse, C., Thisse, B., Canfield, V., Robertson, G., Cheng, K. & Levenson, R., Dec 1 2005, In : Developmental Dynamics. 234, 4, p. 911-921 11 p.

Research output: Contribution to journalArticle

Zebrafish
Embryonic Development
Branchial Region
Embryonic Structures
Central Nervous System
2003
29 Citations (Scopus)

Histology-Based Screen for Zebrafish Mutants with Abnormal Cell Differentiation

Mohideen, M. A. P. K., Beckwith, L. G., Tsao-Wu, G. S., Moore, J. L., Wong, A. C. C., Chinoy, M. R. & Cheng, K., Nov 1 2003, In : Developmental Dynamics. 228, 3, p. 414-423 10 p.

Research output: Contribution to journalArticle

Zebrafish
Cell Differentiation
Histology
Mutation
Photoreceptor Cells
2002
37 Citations (Scopus)

Fixation and decalcification of adult zebrafish for histological, immunocytochemical, and genotypic analysis

Moore, J. L., Aros, M., Steudel, K. G. & Cheng, K., Feb 14 2002, In : BioTechniques. 32, 2, p. 296-298 3 p.

Research output: Contribution to journalArticle

Zebrafish
Tissue
Histology
Edetic Acid
Polymerase Chain Reaction
129 Citations (Scopus)

Life spans and senescent phenotypes in two strains of Zebrafish (Danio rerio)

Gerhard, G. S., Kauffman, E. J., Wang, X., Stewart, R., Moore, J. L., Kasales, C., Demidenko, E. & Cheng, K., Aug 1 2002, In : Experimental Gerontology. 37, 8-9, p. 1055-1068 14 p.

Research output: Contribution to journalArticle

Zebrafish
Spinal Curvatures
Aging of materials
Phenotype
Muscle
2000
17 Citations (Scopus)

Centromere-linked microsatellite markers for linkage groups 3, 4, 6, 7, 13, and 20 of zebrafish (Danio rerio)

Mohideen, M. A. P. K., Moore, J. L. & Cheng, K., Jul 1 2000, In : Genomics. 67, 1, p. 102-106 5 p.

Research output: Contribution to journalArticle

Centromere
Zebrafish
Microsatellite Repeats
Mutation
Species Specificity
63 Citations (Scopus)

Ethylnitrosourea induces neoplasia in zebrafish (Danio rerio)

Beckwith, L. G., Moore, J. L., Tsao-Wu, G. S., Harshbarger, J. C. & Cheng, K., Jan 1 2000, In : Laboratory Investigation. 80, 3, p. 379-385 7 p.

Research output: Contribution to journalArticle

Ethylnitrosourea
Zebrafish
Papilloma
Neoplasms
Fishes
1998
29 Citations (Scopus)

Agarose-embedded tissue arrays for histologic and genetic analysis

Tsao-Wu, G. S., Weber, C. H., Budgeon, L. R. & Cheng, K., Oct 21 1998, In : BioTechniques. 25, 4, p. 614-618 5 p.

Research output: Contribution to journalArticle

Sepharose
Zebrafish
Tissue
Larva
Polymerase Chain Reaction
1997
23 Citations (Scopus)

Genetic dissection of vertebrate processes in the zebrafish: A comparison of uniparental and two-generation screens

Cheng, K. & Moore, J. L., Jan 1 1997, In : Biochemistry and Cell Biology. 75, 5, p. 525-533 9 p.

Research output: Contribution to journalArticle

Dissection
Zebrafish
Vertebrates
Genes
Haploidy
18 Citations (Scopus)

New conditions for generation of gynogenetic half-tetrad embryos in the zebrafish (Danio rerio)

Gestl, E. E., Kauffman, E. J., Moore, J. L. & Cheng, K., Jan 1 1997, In : Journal of Heredity. 88, 1, p. 76-79 4 p.

Research output: Contribution to journalArticle

Zebrafish
Embryonic Structures
Pressure
Microsatellite Repeats
Triploidy
1996
46 Citations (Scopus)

Factors affecting fidelity of DNA synthesis during PCR amplification of d(C-A)n·d(G-T)n microsatellite repeats

Hite, J. M., Eckert, K. & Cheng, K., Jun 15 1996, In : Nucleic acids research. 24, 12, p. 2429-2434 6 p.

Research output: Contribution to journalArticle

Dilatation and Curettage
DNA-Directed DNA Polymerase
Microsatellite Repeats
Exonucleases
Polymerase Chain Reaction
1995
38 Citations (Scopus)

Microsatellite-centromere mapping in the zebrafish (danio rerio)

Kauffman, E. J., Gestl, E. E., Kim, D. J., Walker, C., Hite, J. M., Yan, G., Rogan, P. K., Johnson, S. L. & Cheng, K., Jan 1 1995, In : Genomics. 30, 2, p. 337-341 5 p.

Research output: Contribution to journalArticle

Centromere
Zebrafish
Microsatellite Repeats
Chromosome Mapping
Meiosis
1992
1556 Citations (Scopus)

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions

Cheng, K., Cahill, D. S., Kasai, H., Nishimura, S. & Loeb, L. A., Jan 1 1992, In : Journal of Biological Chemistry. 267, 1, p. 166-172 7 p.

Research output: Contribution to journalArticle

DNA Damage
Substitution reactions
Assays
Mutation
DNA
160 Citations (Scopus)

Genomic instability and tumor progression: Mechanistic considerations

Cheng, K. & Loeb, L. A., Jan 1 1992, In : Advances in Cancer Research. 60, C, p. 121-156 36 p.

Research output: Contribution to journalArticle

Genomic Instability
Neoplasms
Mutation
Mechanics
Cell Size
1991
142 Citations (Scopus)

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G → A transitions in Escherichia coli

Cheng, K., Preston, B. D., Cahill, D. S., Dosanjh, M. K., Singer, B. & Loeb, L. A., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 22, p. 9974-9978 5 p.

Research output: Contribution to journalArticle

Vinyl Chloride
Guanine
Cytosine
DNA-Directed DNA Polymerase
Escherichia coli
1990
42 Citations (Scopus)

Errors in DNA synthesis: A source of spontaneous mutations

Loeb, L. A. & Cheng, K., Jan 1 1990, In : Mutation Research/Reviews in Genetic Toxicology. 238, 3, p. 297-304 8 p.

Research output: Contribution to journalArticle

Mutation
DNA
Mutagenesis
Reactive Oxygen Species
Pathologic Processes
1989
29 Citations (Scopus)

Distribution of Chi-stimulated recombinational exchanges and heteroduplex endpoints in phage lambda.

Cheng, K. & Smith, G. R., Jan 1 1989, In : Genetics. 123, 1, p. 5-17 13 p.

Research output: Contribution to journalArticle

Bacteriophage lambda
Genetic Recombination
DNA
Exodeoxyribonuclease V
Nucleic Acid Heteroduplexes
1987
33 Citations (Scopus)

Cutting of chi-like sequences by the RecBCD enzyme of Escherichia coli

Cheng, K. & Smith, G. R., Apr 20 1987, In : Journal of Molecular Biology. 194, 4, p. 747-750 4 p.

Research output: Contribution to journalArticle

Exodeoxyribonuclease V
Genetic Recombination
Nucleotides
Genetic Crosses
Coliphages