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Kenneth Pak Kin Lee, PhD

    • 429 Citations
    • 5 h-Index
    20072019
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    Fingerprint Dive into the research topics where Kenneth Pak Kin Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    Ribonucleases Medicine & Life Sciences
    Endoplasmic Reticulum Stress Medicine & Life Sciences
    Endoplasmic Reticulum Medicine & Life Sciences
    Unfolded Protein Response Medicine & Life Sciences
    Endoribonucleases Medicine & Life Sciences
    Adenosine Diphosphate Medicine & Life Sciences
    Phosphotransferases Medicine & Life Sciences
    RNA Splicing Medicine & Life Sciences

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    Research Output 2007 2019

    • 429 Citations
    • 5 h-Index
    • 6 Article
    • 1 Chapter

    The remote allosteric control of Orai channel gating

    Zhou, Y., Nwokonko, R. M., Baraniak, J. H., Trebak, M., Lee, K. P. K. & Gill, D. L., Aug 30 2019, In : PLoS biology. 17, 8, e3000413.

    Research output: Contribution to journal › Article

    Open Access
    Remote control
    calcium
    Molecules
    Cell membranes
    Ion Channels
    32 Citations (Scopus)

    Molecular structure of human katp in complex with ATP and ADP

    Lee, K. P. K., Chen, J. & Mackinnon, R., Dec 29 2017, In : eLife. 6, e32481.

    Research output: Contribution to journal › Article

    Open Access
    Molecular Structure
    Adenosine Diphosphate
    Molecular structure
    Adenosine Triphosphate
    KATP Channels
    48 Citations (Scopus)

    Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors

    Sanches, M., Duffy, N. M., Talukdar, M., Thevakumaran, N., Chiovitti, D., Canny, M. D., Lee, K., Kurinov, I., Uehling, D., Al-Awar, R., Poda, G., Prakesch, M., Wilson, B., Tam, V., Schweitzer, C., Toro, A., Lucas, J. L., Vuga, D., Lehmann, L., Durocher, D. & 3 others, Zeng, Q., Patterson, J. B. & Sicheri, F., Aug 28 2014, In : Nature communications. 5, 4202.

    Research output: Contribution to journal › Article

    Open Access
    Endoribonucleases
    aldehydes
    Aldehydes
    inhibitors
    Ribonucleases
    2 Citations (Scopus)

    Principles of IRE1 modulation using chemical tools

    Lee, P. K. K. & Sicheri, F., Jan 1 2011, Methods in Enzymology. C ed. Academic Press Inc., p. 271-294 24 p. (Methods in Enzymology; vol. 490, no. C).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    Endoplasmic Reticulum Stress
    Endoplasmic Reticulum
    Modulation
    Unfolded Protein Response
    Carrier Proteins
    116 Citations (Scopus)

    Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

    Wiseman, R. L., Zhang, Y., Lee, K. P. K., Harding, H. P., Haynes, C. M., Price, J., Sicheri, F. & Ron, D., Apr 23 2010, In : Molecular cell. 38, 2, p. 291-304 14 p.

    Research output: Contribution to journal › Article

    Open Access
    Quercetin
    Ribonucleases
    Phosphotransferases
    Binding Sites
    Ligands