• 435 Citations
  • 5 h-Index
20072019

Research output per year

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Research Output

  • 435 Citations
  • 5 h-Index
  • 6 Article
  • 1 Chapter
2019

The remote allosteric control of Orai channel gating

Zhou, Y., Nwokonko, R. M., Baraniak, J. H., Trebak, M., Lee, K. P. K. & Gill, D. L., Aug 30 2019, In : PLoS biology. 17, 8, e3000413.

Research output: Contribution to journalArticle

Open Access
2017

Molecular structure of human katp in complex with ATP and ADP

Lee, K. P. K., Chen, J. & Mackinnon, R., Dec 29 2017, In : eLife. 6, e32481.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
2014

Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors

Sanches, M., Duffy, N. M., Talukdar, M., Thevakumaran, N., Chiovitti, D., Canny, M. D., Lee, K., Kurinov, I., Uehling, D., Al-Awar, R., Poda, G., Prakesch, M., Wilson, B., Tam, V., Schweitzer, C., Toro, A., Lucas, J. L., Vuga, D., Lehmann, L., Durocher, D. & 3 others, Zeng, Q., Patterson, J. B. & Sicheri, F., Aug 28 2014, In : Nature communications. 5, 4202.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations
2011

Principles of IRE1 modulation using chemical tools

Lee, K. P. K. & Sicheri, F., 2011, Methods in Enzymology. C ed. Academic Press Inc., p. 271-294 24 p. (Methods in Enzymology; vol. 490, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2010

Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

Wiseman, R. L., Zhang, Y., Lee, K. P. K., Harding, H. P., Haynes, C. M., Price, J., Sicheri, F. & Ron, D., Apr 23 2010, In : Molecular cell. 38, 2, p. 291-304 14 p.

Research output: Contribution to journalArticle

Open Access
119 Scopus citations
2008

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

Lee, K. P. K., Dey, M., Neculai, D., Cao, C., Dever, T. E. & Sicheri, F., Jan 11 2008, In : Cell. 132, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

Open Access
208 Scopus citations
2007

Use of modified U1 snRNAs to inhibit HIV-1 replication

Sajic, R., Lee, K., Asai, K., Sakac, D., Branch, D. R., Upton, C. & Cochrane, A., Jan 1 2007, In : Nucleic acids research. 35, 1, p. 247-255 9 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations