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Research Output 1976 2019

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Article
2019
1 Citation (Scopus)

Age and sex differences in sympathetic and hemodynamic responses to hypoxia and cold pressor test

Miller, A. J., Cui, J., Luck, J. C., Sinoway, L. & Muller, M. D., Jan 1 2019, In : Physiological reports. 7, 2, e13988.

Research output: Contribution to journalArticle

Sex Characteristics
Hemodynamics
Thigh
Vasoconstriction
Vasodilation

Habitual cigarette smoking raises pressor responses to spontaneous bursts of muscle sympathetic nerve activity

Cui, J., Drew, R. C., Muller, M. D., Blaha, C., Gonzalez, V. & Sinoway, L., Aug 1 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 317, 2, p. R280-R288

Research output: Contribution to journalArticle

Baroreflex
Smoking
Muscles
Arterial Pressure
Blood Pressure
Catheter Ablation
Atrial Fibrillation
Muscles
Heart Rate
Heart Atria
2018
1 Citation (Scopus)

Peripheral revascularization attenuates the exercise pressor reflex and increases coronary exercise hyperemia in peripheral arterial disease

Miller, A. J., Luck, J. C., Jin-Kwang Kim, D., Leuenberger, U., Aziz, F., Radtka, J., Sinoway, L. & Muller, M. D., Jul 1 2018, In : Journal of Applied Physiology. 125, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Hyperemia
Reflex
Exercise
Blood Pressure
2017
7 Citations (Scopus)

Blood pressure and calf muscle oxygen extraction during plantar flexion exercise in peripheral artery disease

Luck, J. C., Miller, A. J., Aziz, F., Radtka, J., Proctor, D. N., Leuenberger, U., Sinoway, L. & Muller, X. M. D., Jul 1 2017, In : Journal of Applied Physiology. 123, 1, p. 2-10 9 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Exercise
Oxygen
Blood Pressure
Muscles
4 Citations (Scopus)

Blood pressure and leg deoxygenation are exaggerated during treadmill walking in patients with peripheral artery disease

Miller, A. J., Luck, J. C., Kim, D. J. K., Leuenberger, U., Proctor, D. N., Sinoway, L. & Muller, M., Nov 1 2017, In : Journal of Applied Physiology. 123, 5, p. 1160-1165 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Walking
Leg
Blood Pressure
Healthy Volunteers
7 Citations (Scopus)

Coronary Exercise Hyperemia Is Impaired in Patients with Peripheral Arterial Disease

Ross, A. J., Gao, Z., Luck, J. C., Blaha, C. A., Cauffman, A. E., Aziz, F., Radtka, J., Proctor, D. N., Leuenberger, U., Sinoway, L. & Muller, M., Jan 1 2017, In : Annals of Vascular Surgery. 38, p. 260-267 8 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Hyperemia
Exercise
Blood Pressure
Doppler Echocardiography
1 Citation (Scopus)
Peripheral Arterial Disease
Exercise
Muscles
Healthy Volunteers
Leg
6 Citations (Scopus)

Muscle mechanoreflex activation via passive calf stretch causes renal vasoconstriction in healthy humans

Drew, R. C., Blaha, C. A., Herr, M. D., Cui, R. & Sinoway, L., Jun 8 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 6, p. R956-R964

Research output: Contribution to journalArticle

Vasoconstriction
Kidney
Muscles
Vascular Resistance
Exercise
2 Citations (Scopus)
Heat-Shock Response
Heart Failure
Muscles
Healthy Volunteers
Hot Temperature
2016
8 Citations (Scopus)

Muscle oxygenation during dynamic plantar flexion exercise: combining BOLD MRI with traditional physiological measurements

Muller, M., Li, Z., Sica, C. T., Luck, J. C., Gao, Z., Blaha, C. A., Cauffman, A. E., Ross, A. J., Winkler, N. J. R., Herr, M. D., Brandt, K., Wang, J., Gallagher, D. C., Karunanayaka, P., Vesek, J., Leuenberger, U., Yang, Q. & Sinoway, L., Oct 1 2016, In : Physiological reports. 4, 20, e13004.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Exercise
Oxygen
Muscles
Near-Infrared Spectroscopy
1 Citation (Scopus)

Whole body heat stress attenuates the pressure response to muscle metaboreceptor stimulation in humans

Cui, J., Blaha, C. & Sinoway, L., Nov 1 2016, In : Journal of Applied Physiology. 121, 5, p. 1178-1186 9 p.

Research output: Contribution to journalArticle

Hot Temperature
Pressure
Muscles
Blood Pressure
Heart Rate
2015
2 Citations (Scopus)
Baroreflex
Aspirin
Muscles
Heart Rate
Thromboxanes
15 Citations (Scopus)

Inhibition of cyclooxygenase attenuates the blood pressure response to plantar flexion exercise in peripheral arterial disease

Muller, M., Drew, R. C., Ross, A. J., Blaha, C. A., Cauffman, A. E., Kaufman, M. & Sinoway, L., Aug 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 3, p. H523-H528

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Prostaglandin-Endoperoxide Synthases
Arterial Pressure
Exercise
Ketorolac
4 Citations (Scopus)

Limb suction evoked during arterial occlusion causes systemic sympathetic activity in humans

Cui, J., Blaha, C., Herr, M. D., Drew, R. C., Muller, M. & Sinoway, L., Sep 3 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 309, 5, p. R482-R488

Research output: Contribution to journalArticle

Suction
Human Activities
Arm
Extremities
Leg
11 Citations (Scopus)

Seasonal variation in muscle sympathetic nerve activity

Cui, J., Muller, M., Blaha, C., Kunselman, A. & Sinoway, L., Jan 1 2015, In : Physiological reports. 3, 8, e12492.

Research output: Contribution to journalArticle

Muscles
Healthy Volunteers
Morbidity
Mortality
Incidence
2014
12 Citations (Scopus)

Cardiovascular responses to heat stress in chronic heart failure

Cui, J. & Sinoway, L., Jan 1 2014, In : Current Heart Failure Reports. 11, 2, p. 139-145 7 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Heart Failure
Hot Temperature
Skin
Vasodilator Agents
13 Citations (Scopus)
Inhalation
Air
Propranolol
Hand Strength
Lidocaine
3 Citations (Scopus)

Intravenous phentolamine abolishes coronary vasoconstriction in response to mild central hypovolemia

Gao, Z., Muller, M., Sinoway, L. & Leuenberger, U., Jan 15 2014, In : Journal of Applied Physiology. 116, 2, p. 216-221 6 p.

Research output: Contribution to journalArticle

Lower Body Negative Pressure
Hypovolemia
Phentolamine
Vasoconstriction
Blood Pressure
8 Citations (Scopus)

β-Adrenergic blockade enhances coronary vasoconstrictor response to forehead cooling

Muller, M., Gao, Z., Patel, H. M., Heffernan, M. J., Leuenberger, U. & Sinoway, L., Mar 15 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 306, 6

Research output: Contribution to journalArticle

Forehead
Vasoconstrictor Agents
Adrenergic Agents
Blood Flow Velocity
Propranolol
11 Citations (Scopus)

β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men

Ross, A. J., Gao, Z., Pollock, J. P., Leuenberger, U., Sinoway, L. & Muller, M., Nov 15 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 307, 10, p. H1497-H1503

Research output: Contribution to journalArticle

Hyperemia
Adrenergic Receptors
Exercise
Propranolol
Isoproterenol
2013
3 Citations (Scopus)

Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans

Drew, R. C., Muller, M. D., Blaha, C. A., Mast, J. L., Herr, M. D., Stocker, S. & Sinoway, L., Oct 15 2013, In : Journal of Applied Physiology. 115, 8, p. 1183-1190 8 p.

Research output: Contribution to journalArticle

Baroreflex
Aspirin
Heart Rate
Muscles
Thromboxane A2
4 Citations (Scopus)

Assessing the impact of the NIH ctsa program on institutionally sponsored clinical trials

Liu, G., Chen, G., Sinoway, L. & Berg, A., Jun 1 2013, In : Clinical and Translational Science. 6, 3, p. 196-200 5 p.

Research output: Contribution to journalArticle

Clinical Trials
9 Citations (Scopus)

Cardiac mechanics are impaired during fatiguing exercise and cold pressor test in healthy older adults

Muller, M., Mast, J. L., Patel, H. & Sinoway, L., Jan 15 2013, In : Journal of Applied Physiology. 114, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

Mechanics
Exercise
Myocardial Ischemia
19 Citations (Scopus)

Chronic heart failure does not attenuate the total activity of sympathetic outflow to skin during whole-body heating

Cui, J., Boehmer, J., Blaha, C., Lucking, R., Kunselman, A. & Sinoway, L., Mar 1 2013, In : Circulation: Heart Failure. 6, 2, p. 271-278 8 p.

Research output: Contribution to journalArticle

Heating
Heart Failure
Skin
Hot Temperature
Forearm
20 Citations (Scopus)

Contribution of sympathetic activation to coronary vasodilatation during the cold pressor test in healthy men: Effect of ageing

Monahan, K. D., Feehan, R. P., Sinoway, L. & Gao, Z., Jun 1 2013, In : Journal of Physiology. 591, 11, p. 2937-2947 11 p.

Research output: Contribution to journalArticle

Vasodilation
Blood Vessels
Adrenergic Agents
Adrenergic Antagonists
Doppler Echocardiography
10 Citations (Scopus)

Distension of central great vein decreases sympathetic outflow in humans

Cui, J., Gao, Z., Blaha, C., Herr, M. D., Mast, J. & Sinoway, L., Aug 1 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 305, 3

Research output: Contribution to journalArticle

Reflex
Veins
Inferior Vena Cava
Blood Pressure
Heart Rate
15 Citations (Scopus)

Effect of healthy aging on renal vascular responses to local cooling and apnea

Patel, H. M., Mast, J. L., Sinoway, L. & Muller, M., Jul 1 2013, In : Journal of Applied Physiology. 115, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

Apnea
Blood Vessels
Arterial Pressure
Forehead
Kidney
9 Citations (Scopus)
Forearm
Vasodilation
Endothelium
Fluconazole
omega-N-Methylarginine
12 Citations (Scopus)
Reducing Diet
Hyperoxia
Vasoconstriction
Oxidative Stress
Weight Loss
7 Citations (Scopus)

Microfluidic opportunities in the field of nutrition

Li, S., Kiehne, J., Sinoway, L., Cameron, C. E. & Huang, T. J., Oct 21 2013, In : Lab on a Chip. 13, 20, p. 3993-4003 11 p.

Research output: Contribution to journalArticle

Microfluidics
Nutrition
Lab-On-A-Chip Devices
Biomarkers
Point-of-Care Systems
11 Citations (Scopus)

Renal vasoconstriction is augmented during exercise in patients with peripheral arterial disease

Drew, R. C., Muller, M., Blaha, C. A., Mast, J. L., Heffernan, M. J., Estep, L. E., Cui, J., Reed, A. B. & Sinoway, L., Jan 1 2013, In : Physiological reports. 1, 6, p. 1-9 9 p., e00154.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Vasoconstriction
Exercise
Kidney
Vascular Resistance
4 Citations (Scopus)

Tactile stimulation of the oropharynx elicits sympathoexcitation in conscious humans

Muller, M., Mast, J. L., Cui, J., Heffernan, M. J., McQuillan, P. & Sinoway, L., Jul 1 2013, In : Journal of Applied Physiology. 115, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Oropharynx
Touch
Reflex
Arterial Pressure
Heart Rate
2012
22 Citations (Scopus)
Hand Strength
Respiration
Air
Pressure
Inhalation
26 Citations (Scopus)
Extremities
Blood Pressure
Muscles
Lidocaine
Forearm
50 Citations (Scopus)

Oxidative stress contributes to the augmented exercise pressor reflex in peripheral arterial disease patients

Muller, M., Drew, R. C., Blaha, C. A., Mast, J. L., Cui, J., Reed, A. B. & Sinoway, L., Dec 1 2012, In : Journal of Physiology. 590, 23, p. 6237-6246 10 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Reflex
Oxidative Stress
Exercise
Blood Pressure
12 Citations (Scopus)
Health
Maintenance
Research Personnel
Education
National Center for Advancing Translational Sciences (U.S.)
31 Citations (Scopus)

Vitamin C prevents hyperoxia-mediated coronary vasoconstriction and impairment of myocardial function in healthy subjects

Gao, Z., Spilk, S., Momen, A., Muller, M., Leuenberger, U. & Sinoway, L., Feb 1 2012, In : European Journal of Applied Physiology. 112, 2, p. 483-492 10 p.

Research output: Contribution to journalArticle

Hyperoxia
Vasoconstriction
Ascorbic Acid
Healthy Volunteers
Left Ventricular Function
2011
23 Citations (Scopus)

Effect of cold air inhalation and isometric exercise on coronary blood flow and myocardial function in humans

Muller, M., Gao, Z., Drew, R. C., Herr, M. D., Leuenberger, U. & Sinoway, L., Dec 1 2011, In : Journal of Applied Physiology. 111, 6, p. 1694-1702 9 p.

Research output: Contribution to journalArticle

Inhalation
Air
Exercise
Hand Strength
Pressure
17 Citations (Scopus)

Effect of P2 receptor blockade with pyridoxine on sympathetic response to exercise pressor reflex in humans

Cui, J., Leuenberger, U., Blaha, C., King, N. C. & Sinoway, L., Feb 1 2011, In : Journal of Physiology. 589, 3, p. 685-695 11 p.

Research output: Contribution to journalArticle

Pyridoxine
Reflex
Exercise
Purinergic P2 Receptors
Blood Pressure
17 Citations (Scopus)
Forearm
Extremities
Muscles
Blood Pressure
Blood Vessels
12 Citations (Scopus)
Transient Receptor Potential Channels
Reflex
Muscles
Kidney
Bradykinin
2010
12 Citations (Scopus)
Bradykinin Receptors
Muscle Contraction
Heart Failure
Muscles
Reflex
15 Citations (Scopus)

Coronary vasoconstrictor responses are attenuated in young women as compared with age-matched men

Momen, A., Gao, Z., Cohen, A., Khan, T., Leuenberger, U. & Sinoway, L., Oct 1 2010, In : Journal of Physiology. 588, 20, p. 4007-4016 10 p.

Research output: Contribution to journalArticle

Vasoconstrictor Agents
Lower Body Negative Pressure
Constriction
Exercise
Coronary Vessels
7 Citations (Scopus)
Purinergic P1 Receptors
Exercise
Muscles
Aminophylline
Blood Pressure
12 Citations (Scopus)
Mammary Arteries
Doppler Echocardiography
Vasoconstrictor Agents
Echocardiography
Blood Flow Velocity
2009
49 Citations (Scopus)

Coronary blood flow responses to physiological stress in humans

Momen, A., Mascarenhas, V., Gahremanpour, A., Gao, Z., Moradkhan, R., Kunselman, A., Boehmer, J., Sinoway, L. & Leuenberger, U., Mar 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 3

Research output: Contribution to journalArticle

Physiological Stress
Hyperoxia
Lower Body Negative Pressure
Blood Pressure
Vasoconstriction
28 Citations (Scopus)

Oxidative stress and the muscle reflex in heart failure

Koba, S., Gao, Z. & Sinoway, L., Nov 1 2009, In : Journal of Physiology. 587, 21, p. 5227-5237 11 p.

Research output: Contribution to journalArticle

Reflex
Oxidative Stress
Heart Failure
Muscles
Superoxides
11 Citations (Scopus)

Sex differences in limb vasoconstriction responses to increases in transmural pressures

Lott, M. E. J., Hogeman, C., Herr, M., Bhagat, M. & Sinoway, L., Jan 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 1

Research output: Contribution to journalArticle

Vasoconstriction
Sex Characteristics
Extremities
Pressure
Arm
3 Citations (Scopus)

Spinal P2X receptor modulates muscle pressor reflex via glutamate

Li, J., Lu, J., Gao, Z., Koba, S., Xing, J., King, N. & Sinoway, L., Mar 1 2009, In : Journal of Applied Physiology. 106, 3, p. 865-870 6 p.

Research output: Contribution to journalArticle

Reflex
Glutamic Acid
Muscles
Excitatory Amino Acids
Spinal Nerve Roots