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1976 …2022
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Research Output 1976 2018

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2018

Peripheral revascularization attenuates the exercise pressor reflex and increases coronary exercise hyperemia in peripheral arterial disease

Miller, A. J., Luck, J. C., Jin-Kwang Kim, D., Leuenberger, U. A., Aziz, F., Radtka, J. F., Sinoway, L. I. & Muller, M. D., Jul 1 2018, In : Journal of Applied Physiology. 125, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Hyperemia
Reflex
Exercise
Blood Pressure
2017
4 Citations

Blood pressure and calf muscle oxygen extraction during plantar flexion exercise in peripheral artery disease

Luck, J. C., Miller, A. J., Aziz, F., Radtka, J. F., Proctor, D. N., Leuenberger, U. A., Sinoway, L. I. & Muller, X. M. D., Jul 1 2017, In : Journal of Applied Physiology. 123, 1, p. 2-10 9 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Exercise
Oxygen
Blood Pressure
Muscles
1 Citations

Blood pressure and leg deoxygenation are exaggerated during treadmill walking in patients with peripheral artery disease

Miller, A. J., Luck, J. C., Kim, D. J. K., Leuenberger, U. A., Proctor, D. N., Sinoway, L. I. & Muller, M. D., Nov 1 2017, In : Journal of Applied Physiology. 123, 5, p. 1160-1165 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Walking
Leg
Blood Pressure
Healthy Volunteers
6 Citations

Coronary Exercise Hyperemia Is Impaired in Patients with Peripheral Arterial Disease

Ross, A. J., Gao, Z., Luck, J. C., Blaha, C. A., Cauffman, A. E., Aziz, F., Radtka, J. F., Proctor, D. N., Leuenberger, U. A., Sinoway, L. I. & Muller, M. D., Jan 1 2017, In : Annals of Vascular Surgery. 38, p. 260-267 8 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Hyperemia
Exercise
Blood Pressure
Doppler Echocardiography
Peripheral Arterial Disease
Exercise
Muscles
Healthy Volunteers
Leg
2 Citations

Muscle mechanoreflex activation via passive calf stretch causes renal vasoconstriction in healthy humans

Drew, R. C., Blaha, C. A., Herr, M. D., Cui, R. & Sinoway, L. I., Jun 8 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 6, p. R956-R964

Research output: Contribution to journalArticle

Vasoconstriction
Kidney
Muscles
Vascular Resistance
Exercise
1 Citations
Heat-Shock Response
Heart Failure
Muscles
Healthy Volunteers
Hot Temperature
2016
5 Citations

Muscle oxygenation during dynamic plantar flexion exercise: combining BOLD MRI with traditional physiological measurements

Muller, M. D., Li, Z., Sica, C. T., Luck, J. C., Gao, Z., Blaha, C. A., Cauffman, A. E., Ross, A. J., Winkler, N. J. R., Herr, M. D., Brandt, K., Wang, J., Gallagher, D. C., Karunanayaka, P., Vesek, J., Leuenberger, U. A., Yang, Q. X. & Sinoway, L. I., Oct 1 2016, In : Physiological reports. 4, 20, e13004

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Exercise
Oxygen
Muscles
Near-Infrared Spectroscopy

Whole body heat stress attenuates the pressure response to muscle metaboreceptor stimulation in humans

Cui, J., Blaha, C. & Sinoway, L. I., Nov 1 2016, In : Journal of Applied Physiology. 121, 5, p. 1178-1186 9 p.

Research output: Contribution to journalArticle

Hot Temperature
Pressure
Muscles
Blood Pressure
Heart Rate
2015
2 Citations

Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation

Drew, R. C., Blaha, C. A., Herr, M. D., Stocker, S. D. & Sinoway, L. I., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 8, p. H1361-H1369

Research output: Contribution to journalArticle

Baroreflex
Aspirin
Muscles
Heart Rate
Thromboxanes
12 Citations

Inhibition of cyclooxygenase attenuates the blood pressure response to plantar flexion exercise in peripheral arterial disease

Muller, M. D., Drew, R. C., Ross, A. J., Blaha, C. A., Cauffman, A. E., Kaufman, M. P. & Sinoway, L. I., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 3, p. H523-H528

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Prostaglandin-Endoperoxide Synthases
Ketorolac
Arterial Pressure
Exercise
3 Citations

Limb suction evoked during arterial occlusion causes systemic sympathetic activity in humans

Cui, J., Blaha, C., Herr, M. D., Drew, R. C., Muller, M. D. & Sinoway, L. I., Sep 3 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 309, 5, p. R482-R488

Research output: Contribution to journalArticle

Suction
Human Activities
Arm
Extremities
Leg
5 Citations

Seasonal variation in muscle sympathetic nerve activity

Cui, J., Muller, M. D., Blaha, C., Kunselman, A. R. & Sinoway, L. I., Jan 1 2015, In : Physiological reports. 3, 8, e12492

Research output: Contribution to journalArticle

Muscles
Healthy Volunteers
Morbidity
Mortality
Incidence
2014
10 Citations

Cardiovascular responses to heat stress in chronic heart failure

Cui, J. & Sinoway, L. I., Jan 1 2014, In : Current Heart Failure Reports. 11, 2, p. 139-145 7 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Heart Failure
Hot Temperature
Skin
Vasodilator Agents
11 Citations
Inhalation
Air
Propranolol
Hand Strength
Lidocaine
3 Citations

Intravenous phentolamine abolishes coronary vasoconstriction in response to mild central hypovolemia

Gao, Z., Muller, M. D., Sinoway, L. I. & Leuenberger, U. A., Jan 15 2014, In : Journal of Applied Physiology. 116, 2, p. 216-221 6 p.

Research output: Contribution to journalArticle

Lower Body Negative Pressure
Hypovolemia
Phentolamine
Vasoconstriction
Blood Pressure
7 Citations

β-Adrenergic blockade enhances coronary vasoconstrictor response to forehead cooling

Muller, M. D., Gao, Z., Patel, H. M., Heffernan, M. J., Leuenberger, U. A. & Sinoway, L. I., Mar 15 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 306, 6

Research output: Contribution to journalArticle

Forehead
Vasoconstrictor Agents
Adrenergic Agents
Blood Flow Velocity
Propranolol
9 Citations

β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men

Ross, A. J., Gao, Z., Pollock, J. P., Leuenberger, U. A., Sinoway, L. I. & Muller, M. D., Jan 1 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 307, 10, p. H1497-H1503

Research output: Contribution to journalArticle

Receptors, Adrenergic, beta
Hyperemia
Exercise
Propranolol
Isoproterenol
2013
3 Citations

Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans

Drew, R. C., Muller, M. D., Blaha, C. A., Mast, J. L., Herr, M. D., Stocker, S. D. & Sinoway, L. I., Oct 15 2013, In : Journal of Applied Physiology. 115, 8, p. 1183-1190 8 p.

Research output: Contribution to journalArticle

Baroreflex
Aspirin
Heart Rate
Muscles
Thromboxane A2
2 Citations

Assessing the impact of the NIH ctsa program on institutionally sponsored clinical trials

Liu, G., Chen, G., Sinoway, L. I. & Berg, A., Jun 1 2013, In : Clinical and Translational Science. 6, 3, p. 196-200 5 p.

Research output: Contribution to journalArticle

Clinical Trials
9 Citations

Cardiac mechanics are impaired during fatiguing exercise and cold pressor test in healthy older adults

Muller, M. D., Mast, J. L., Patel, H. & Sinoway, L. I., Jan 15 2013, In : Journal of Applied Physiology. 114, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

Mechanics
Exercise
Myocardial Ischemia
16 Citations
Heating
Heart Failure
Skin
Hot Temperature
Forearm
16 Citations

Contribution of sympathetic activation to coronary vasodilatation during the cold pressor test in healthy men: Effect of ageing

Monahan, K. D., Feehan, R. P., Sinoway, L. I. & Gao, Z., Jun 2013, In : Journal of Physiology. 591, 11, p. 2937-2947 11 p.

Research output: Contribution to journalArticle

Vasodilation
Adrenergic Agents
Blood Vessels
Adrenergic alpha-Antagonists
Adrenergic beta-Antagonists
9 Citations

Distension of central great vein decreases sympathetic outflow in humans

Cui, J., Gao, Z., Blaha, C., Herr, M. D., Mast, J. & Sinoway, L. I., Aug 1 2013, In : American Journal of Physiology - Heart and Circulatory Physiology. 305, 3

Research output: Contribution to journalArticle

Reflex
Veins
Inferior Vena Cava
Blood Pressure
Heart Rate
13 Citations

Effect of healthy aging on renal vascular responses to local cooling and apnea

Patel, H. M., Mast, J. L., Sinoway, L. I. & Muller, M. D., Jul 1 2013, In : Journal of Applied Physiology. 115, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

Apnea
Blood Vessels
Arterial Pressure
Forehead
Kidney
9 Citations
Forearm
Vasodilation
Endothelium
Fluconazole
Skeletal Muscle
11 Citations
Reducing Diet
Hyperoxia
Vasoconstriction
Oxidative Stress
Weight Loss
6 Citations

Microfluidic opportunities in the field of nutrition

Li, S., Kiehne, J., Sinoway, L. I., Cameron, C. E. & Huang, T. J., Oct 21 2013, In : Lab on a Chip. 13, 20, p. 3993-4003 11 p.

Research output: Contribution to journalArticle

Microfluidics
Nutrition
Lab-On-A-Chip Devices
Biomarkers
Point-of-Care Systems
9 Citations

Renal vasoconstriction is augmented during exercise in patients with peripheral arterial disease

Drew, R. C., Muller, M. D., Blaha, C. A., Mast, J. L., Heffernan, M. J., Estep, L. E., Cui, J., Reed, A. B. & Sinoway, L. I., Jan 1 2013, In : Physiological reports. 1, 6, p. 1-9 9 p., e00154

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Vasoconstriction
Exercise
Kidney
Vascular Resistance
4 Citations

Tactile stimulation of the oropharynx elicits sympathoexcitation in conscious humans

Muller, M. D., Mast, J. L., Cui, J., Heffernan, M. J., McQuillan, P. M. & Sinoway, L. I., Jul 1 2013, In : Journal of Applied Physiology. 115, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Oropharynx
Touch
Reflex
Arterial Pressure
Heart Rate
2012
21 Citations
Hand Strength
Respiration
Air
Pressure
Inhalation
23 Citations
Extremities
Blood Pressure
Muscles
Lidocaine
Forearm
43 Citations

Oxidative stress contributes to the augmented exercise pressor reflex in peripheral arterial disease patients

Muller, M. D., Drew, R. C., Blaha, C. A., Mast, J. L., Cui, J., Reed, A. B. & Sinoway, L. I., Dec 2012, In : Journal of Physiology. 590, 23, p. 6237-6246 10 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Reflex
Oxidative Stress
Exercise
Blood Pressure
10 Citations
Health
Maintenance
Research Personnel
Education
National Center for Advancing Translational Sciences (U.S.)
30 Citations

Vitamin C prevents hyperoxia-mediated coronary vasoconstriction and impairment of myocardial function in healthy subjects

Gao, Z., Spilk, S., Momen, A., Muller, M. D., Leuenberger, U. A. & Sinoway, L. I., Feb 1 2012, In : European Journal of Applied Physiology. 112, 2, p. 483-492 10 p.

Research output: Contribution to journalArticle

Hyperoxia
Vasoconstriction
Ascorbic Acid
Healthy Volunteers
Left Ventricular Function
2011
22 Citations

Effect of cold air inhalation and isometric exercise on coronary blood flow and myocardial function in humans

Muller, M. D., Gao, Z., Drew, R. C., Herr, M. D., Leuenberger, U. A. & Sinoway, L. I., Dec 1 2011, In : Journal of Applied Physiology. 111, 6, p. 1694-1702 9 p.

Research output: Contribution to journalArticle

Inhalation
Air
Exercise
Hand Strength
Pressure
17 Citations

Effect of P2 receptor blockade with pyridoxine on sympathetic response to exercise pressor reflex in humans

Cui, J., Leuenberger, U. A., Blaha, C., King, N. C. & Sinoway, L. I., Feb 1 2011, In : Journal of Physiology. 589, 3, p. 685-695 11 p.

Research output: Contribution to journalArticle

Pyridoxine
Reflex
Exercise
Purinergic P2 Receptors
Blood Pressure
16 Citations
Forearm
Extremities
Muscles
Blood Pressure
Blood Vessels
12 Citations
Transient Receptor Potential Channels
Reflex
Muscles
Kidney
Bradykinin
2010
12 Citations
Bradykinin Receptors
Muscle Contraction
Heart Failure
Muscles
Reflex
15 Citations

Coronary vasoconstrictor responses are attenuated in young women as compared with age-matched men

Momen, A., Gao, Z., Cohen, A., Khan, T., Leuenberger, U. A. & Sinoway, L. I., Oct 1 2010, In : Journal of Physiology. 588, 20, p. 4007-4016 10 p.

Research output: Contribution to journalArticle

Vasoconstrictor Agents
Lower Body Negative Pressure
Constriction
Exercise
Coronary Vessels
7 Citations
Purinergic P1 Receptors
Exercise
Muscles
Aminophylline
Blood Pressure
12 Citations
Mammary Arteries
Doppler Echocardiography
Vasoconstrictor Agents
Echocardiography
Blood Flow Velocity
2009
45 Citations

Coronary blood flow responses to physiological stress in humans

Momen, A., Mascarenhas, V., Gahremanpour, A., Gao, Z., Moradkhan, R., Kunselman, A., Boehmer, J. P., Sinoway, L. I. & Leuenberger, U. A., Mar 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 3

Research output: Contribution to journalArticle

Physiological Stress
Hyperoxia
Lower Body Negative Pressure
Blood Pressure
Vasoconstriction
28 Citations

Oxidative stress and the muscle reflex in heart failure

Koba, S., Gao, Z. & Sinoway, L. I., Nov 2009, In : Journal of Physiology. 587, 21, p. 5227-5237 11 p.

Research output: Contribution to journalArticle

Reflex
Oxidative Stress
Heart Failure
Muscles
Superoxides
10 Citations

Sex differences in limb vasoconstriction responses to increases in transmural pressures

Lott, M. E. J., Hogeman, C., Herr, M., Bhagat, M. & Sinoway, L. I., Jan 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 1

Research output: Contribution to journalArticle

Vasoconstriction
Sex Characteristics
Extremities
Pressure
Arm
3 Citations

Spinal P2X receptor modulates muscle pressor reflex via glutamate

Li, J., Lu, J., Gao, Z., Koba, S., Xing, J., King, N. & Sinoway, L., Mar 1 2009, In : Journal of Applied Physiology. 106, 3, p. 865-870 6 p.

Research output: Contribution to journalArticle

Reflex
Glutamic Acid
Muscles
Excitatory Amino Acids
Spinal Nerve Roots
16 Citations

Sympathetic responses during saline infusion into the veins of an occluded limb

Cui, J., McQuillan, P., Moradkhan, R., Pagana, C. & Sinoway, L. I., Jul 15 2009, In : Journal of Physiology. 587, 14, p. 3619-3627 9 p.

Research output: Contribution to journalArticle

Veins
Extremities
Blood Pressure
Muscles
Blood Vessels
13 Citations

Vasoconstrictor responses in the upper and lower limbs to increases in transmural pressure

Lott, M. E. J., Hogeman, C., Herr, M., Bhagat, M., Kunselman, A. & Sinoway, L. I., Jan 1 2009, In : Journal of Applied Physiology. 106, 1, p. 302-310 9 p.

Research output: Contribution to journalArticle

Suction
Vasoconstrictor Agents
Lower Extremity
Pressure
Arm
2008
9 Citations

20-HETE increases renal sympathetic nerve activity via activation of chemically and mechanically sensitive muscle afferents

Gao, Z., Koba, S., Sinoway, L. & Li, J., May 15 2008, In : Journal of Physiology. 586, 10, p. 2581-2591 11 p.

Research output: Contribution to journalArticle

Kidney
Muscles
Reflex
Prostaglandin-Endoperoxide Synthases
Arachidonic Acid