• 949 Citations
  • 13 h-Index
19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 949 Citations
  • 13 h-Index
  • 21 Article
  • 2 Review article
  • 1 Chapter
2019

Arf GTPases and their GEFs and GAPS: Concepts and challenges

Sztul, E., Chen, P. W., Casanova, J. E., Cherfils, J., Dacks, J. B., Lambright, D. G., Lee, F. J. S., Randazzo, P. A., Santy, L. C., Schürmann, A., Wilhelmi, I., Yohe, M. E. & Kahn, R. A., Jan 1 2019, In : Molecular biology of the cell. 30, 11, p. 1249-1271 23 p.

Research output: Contribution to journalReview article

Open Access
9 Scopus citations

A traction force threshold signifies metastatic phenotypic change in multicellular epithelia

Zhang, Y., Shi, X., Zhao, T., Huang, C., Wei, Q., Tang, X., Santy, L. C., Saif, M. T. A. & Zhang, S., Jan 1 2019, In : Soft matter. 15, 36, p. 7203-7210 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation

Koubek, E. J. & Santy, L. C., May 4 2018, In : Small GTPases. 9, 3, p. 242-259 18 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment

Salem, J. C., Reviriego-Mendoza, M. M. & Santy, L. C., Nov 15 2015, In : Molecular biology of the cell. 26, 23, p. 4265-4279 15 p.

Research output: Contribution to journalArticle

4 Scopus citations
9 Scopus citations
2013

The cytohesin coiled-coil domain interacts with threonine 276 to control membrane association

Hiester, K. G. & Santy, L. C., Nov 26 2013, In : PloS one. 8, 11, e82084.

Research output: Contribution to journalArticle

12 Scopus citations
9 Scopus citations
2012

CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration

Attar, M. A., Salem, J. C., Pursel, H. S. & Santy, L. C., Feb 1 2012, In : Experimental Cell Research. 318, 3, p. 228-237 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

Leshner, M., Wang, S., Lewis, C., Zheng, H., Chen, X. A., Santy, L. & Wang, Y., Dec 1 2012, In : Frontiers in immunology. 3, OCT, Article 307.

Research output: Contribution to journalArticle

155 Scopus citations

Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling

Oh, S. J. & Santy, L. C., Jul 1 2012, In : Journal of Cell Science. 125, 13, p. 3195-3201 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

Differential effects of cytohesins 2 and 3 on β1 integrin recycling

Oh, S. J. & Santy, L. C., May 7 2010, In : Journal of Biological Chemistry. 285, 19, p. 14610-14616 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180

White, D. T., McShea, K. M., Attar, M. A. & Santy, L. C., Feb 15 2010, In : Molecular biology of the cell. 21, 4, p. 562-571 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
2006

ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway

Clarke, M., Ewart, M. A., Santy, L. C., Prekeris, R. & Gould, G. W., Apr 21 2006, In : Biochemical and Biophysical Research Communications. 342, 4, p. 1361-1367 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

ARNO through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells

Shmuel, M., Santy, L. C., Frank, S., Avrahami, D., Casanova, J. E. & Altschuler, Y., May 12 2006, In : Journal of Biological Chemistry. 281, 19, p. 13300-13308 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2005

The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1

Santy, L. C., Ravichandran, K. S. & Casanova, J. E., Oct 11 2005, In : Current Biology. 15, 19, p. 1749-1754 6 p.

Research output: Contribution to journalArticle

114 Scopus citations
2004

The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6

Martinu, L., Masuda-Robens, J. M., Robertson, S. E., Santy, L. C., Casanova, J. E. & Chou, M. M., Nov 1 2004, In : Molecular and cellular biology. 24, 22, p. 9752-9762 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
2003

The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin

Li, H. S., Shome, K., Rojas, R., Rizzo, M. A., Vasudevan, C., Fluharty, E., Santy, L. C., Casanova, J. E. & Romero, G., Jan 6 2003, In : BMC Cell Biology. 4, 13.

Research output: Contribution to journalArticle

25 Scopus citations
2002

Characterization of a fast cycling ADP-ribosylation factor 6 mutant

Santy, L. C., Oct 25 2002, In : Journal of Biological Chemistry. 277, 43, p. 40185-40188 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

GTPase signaling: Bridging the GAP between ARF and Rho

Santy, L. C. & Casanova, J. E., May 14 2002, In : Current Biology. 12, 10, p. R360-R362

Research output: Contribution to journalReview article

22 Scopus citations
2001

Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D

Santy, L. C. & Casanova, J. E., Aug 6 2001, In : Journal of Cell Biology. 154, 3, p. 599-610 12 p.

Research output: Contribution to journalArticle

294 Scopus citations

Expression and analysis of ARNO and ARNO mutants and their effects on adp-ribosylation factor (ARF)-mediated actin cytoskeletal rearrangements

Santy, L. C., Frank, S. R. & Casanova, J. E., Jan 1 2001, Methods in Enzymology. Academic Press Inc., p. 256-264 9 p. (Methods in Enzymology; vol. 329).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations
1999

Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch

Santy, L. C., Frank, S. R., Hatfield, J. C. & Casanova, J. E., Oct 21 1999, In : Current Biology. 9, 20, p. 1173-1176 4 p.

Research output: Contribution to journalArticle

51 Scopus citations
1997
1996

Reconstitution and characterization of two forms of cyclic nucleotide-gated channels from skeletal muscle

Santy, L. C. & Guidotti, G., Dec 1 1996, In : American Journal of Physiology. 271, 6 PART 1, p. E1051-E1060

Research output: Contribution to journalArticle

4 Scopus citations