Mack Ruffin, MD, MPH

    • 6089 Citations
    • 41 h-Index
    1977 …2021

    Research output per year

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    Research Output

    Article

    Isobaric protein-level labeling strategy for serum glycoprotein quantification analysis by liquid chromatography-tandem mass spectrometry

    Nie, S., Lo, A., Zhu, J., Wu, J., Ruffin, M. T. & Lubman, D. M., Jun 4 2013, In : Analytical chemistry. 85, 11, p. 5353-5357 5 p.

    Research output: Contribution to journalArticle

    17 Scopus citations

    Label-free relative quantification of alpha-2-macroglobulin site-specific core-fucosylation in pancreatic cancer by LC-MS/MS

    Lin, Z., Yin, H., Lo, A., Ruffin, M. T., Anderson, M. A., Simeone, D. M. & Lubman, D. M., Aug 2014, In : ELECTROPHORESIS. 35, 15, p. 2108-2115 8 p.

    Research output: Contribution to journalArticle

    17 Scopus citations

    Lack of HPV 16 and 18 detection in serum of colposcopy clinic patients

    Patel, D. A., Unger, E. R., Walline, H., Opipari, A. W., Lee, D. R., Flowers, L. C. & Ruffin, M., Apr 1 2011, In : Journal of Clinical Virology. 50, 4, p. 342-344 3 p.

    Research output: Contribution to journalArticle

    1 Scopus citations

    Large-scale identification of core-fucosylated glycopeptide sites in pancreatic cancer serum using mass spectrometry

    Tan, Z., Yin, H., Nie, S., Lin, Z., Zhu, J., Ruffin, M. T., Anderson, M. A., Simeone, D. M. & Lubman, D. M., Apr 3 2015, In : Journal of Proteome Research. 14, 4, p. 1968-1978 11 p.

    Research output: Contribution to journalArticle

    43 Scopus citations

    Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III

    Ruffin, M., Bailey, J. M., Normolle, D. P., Michael, C. W., Bieniasz, M. E., Kmak, D. C., Unger, E. R. & Brenner, D. E., Dec 1 2004, In : Cancer Epidemiology Biomarkers and Prevention. 13, 12, p. 2148-2152 5 p.

    Research output: Contribution to journalArticle

    23 Scopus citations

    Markers of systemic exposures to products of intestinal bacteria in a dietary intervention study

    Umoh, F. I., Kato, I., Ren, J., Wachowiak, P. L., Ruffin, M. T., Turgeon, D. K., Sen, A., Brenner, D. E. & Djuric, Z., Mar 1 2016, In : European Journal of Nutrition. 55, 2, p. 793-798 6 p.

    Research output: Contribution to journalArticle

    13 Scopus citations

    Mass spectrometric assay for analysis of haptoglobin fucosylation in pancreatic cancer

    Lin, Z., Simeone, D. M., Anderson, M. A., Brand, R. E., Xie, X., Shedden, K. A., Ruffin, M. & Lubman, D. M., May 6 2011, In : Journal of Proteome Research. 10, 5, p. 2602-2611 10 p.

    Research output: Contribution to journalArticle

    58 Scopus citations

    Maternal characteristics that predict a preference for mandatory adolescent HPV vaccination

    Carlos, R. C., Dempsey, A. F., Resnicow, K., Ruffin, M., Patel, D. A., Straus, C. M. & Dalton, V. K., Feb 1 2011, In : Human Vaccines. 7, 2, p. 225-229 5 p.

    Research output: Contribution to journalArticle

    5 Scopus citations

    Measuring cervical cancer risk: Development and validation of the CARE Risky Sexual Behavior Index

    Reiter, P. L., Katz, M. L., Ferketich, A. K., Ruffin, M. T. & Paskett, E. D., Dec 2009, In : Cancer Causes and Control. 20, 10, p. 1865-1871 7 p.

    Research output: Contribution to journalArticle

    16 Scopus citations

    Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions

    Baxter, N. T., Ruffin, M. T., Rogers, M. A. M. & Schloss, P. D., Apr 6 2016, In : Genome Medicine. 8, 1, 37.

    Research output: Contribution to journalArticle

    75 Scopus citations

    Microsatellite instability and DNA mismatch repair protein deficiency in lynch syndrome colorectal polyps

    Yurgelun, M. B., Goel, A., Hornick, J. L., Sen, A., Turgeon, D. K., Ruffin IV, M. T., Marcon, N. E., Baron, J. A., Bresalier, R. S., Syngal, S., Brenner, D. E., Boland, C. R. & Stoffel, E. M., Apr 1 2012, In : Cancer Prevention Research. 5, 4, p. 574-582 9 p.

    Research output: Contribution to journalArticle

    69 Scopus citations

    Missed adenomas during colonoscopic surveillance in individuals with Lynch syndrome (hereditary nonpolyposis colorectal cancer)

    Stoffel, E. M., Kim Turgeon, D., Stockwell, D. H., Zhao, L., Normolle, D. P., Tuck, M. K., Bresalier, R. S., Marcon, N. E., Baron, J. A., Ruffin, M. T., Brenner, D. E. & Syngal, S., Nov 1 2008, In : Cancer Prevention Research. 1, 6, p. 470-475 6 p.

    Research output: Contribution to journalArticle

    84 Scopus citations

    National patterns in human papillomavirus vaccination: An analysis of the national survey of family growth

    Sadigh, G., Dempsey, A. F., Ruffin IV, M. T., Resnicow, K. & Carlos, R. C., Feb 2012, In : Human Vaccines and Immunotherapeutics. 8, 2, p. 234-242 9 p.

    Research output: Contribution to journalArticle

    14 Scopus citations

    Normalization of the microbiota in patients after treatment for colonic lesions

    Sze, M. A., Baxter, N. T., Ruffin, M. T., Rogers, M. A. M. & Schloss, P. D., Nov 16 2017, In : Microbiome. 5, 1, 1 p.

    Research output: Contribution to journalArticle

    11 Scopus citations

    Original contributions. Improving the yield of endocervical elements in a pap smear with the use of the cytology brush

    Ruffin, M. T. & Van Noord, G. R., Jan 1 1991, In : Family medicine. 23, 5, p. 365-369 5 p.

    Research output: Contribution to journalArticle

    5 Scopus citations

    Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer

    Demark-Wahnefried, W., George, S. L., Switzer, B. R., Snyder, D. C., Madden, J. F., Polascik, T. J., Ruffin, M. T. & Vollmer, R. T., Dec 1 2008, In : Clinical Trials. 5, 3, p. 262-272 11 p.

    Research output: Contribution to journalArticle

    15 Scopus citations

    Pancreatic cancer serum detection using a lectin/glyco-antibody array method

    Li, C., Simeone, D. M., Brenner, D. E., Anderson, M. A., Shedden, K. A., Ruffin, M. T. & Lubman, D. M., Feb 1 2009, In : Journal of Proteome Research. 8, 2, p. 483-492 10 p.

    Research output: Contribution to journalArticle

    88 Scopus citations

    Patient and clinic factors associated with adolescent human papillomavirus vaccine utilization within a university-based health system

    Dempsey, A., Cohn, L., Dalton, V. & Ruffin, M., Jan 22 2010, In : Vaccine. 28, 4, p. 989-995 7 p.

    Research output: Contribution to journalArticle

    77 Scopus citations

    Patients' Interpretation of Qualitative Probability Statements

    Woloshin, K. K., Ruffin, M. & Gorenflo, D. W., Jan 1 1994, In : Archives of family medicine. 3, 11, p. 961-966 6 p.

    Research output: Contribution to journalArticle

    36 Scopus citations

    Patterns of cellular and HPV 16 methylation as biomarkers for cervical neoplasia

    Patel, D. A., Rozek, L. S., Colacino, J. A., Van Zomeren-Dohm, A., Ruffin, M., Unger, E. R., Dolinoy, D. C., Swan, D. C., Onyekwuluje, J., DeGraffinreid, C. R. & Paskett, E. D., Sep 1 2012, In : Journal of Virological Methods. 184, 1-2, p. 84-92 9 p.

    Research output: Contribution to journalArticle

    18 Scopus citations
    10 Scopus citations

    Personal genomic testing for cancer risk: Results from the impact of personal genomics study

    Gray, S. W., Gollust, S. E., Carere, D. A., Chen, C. A., Cronin, A., Kalia, S. S., Rana, H. Q., Ruffin Iv, M. T., Wang, C., Roberts, J. S. & Green, R. C., Feb 20 2017, In : Journal of Clinical Oncology. 35, 6, p. 636-644 9 p.

    Research output: Contribution to journalArticle

    15 Scopus citations

    Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthyhuman subjects

    Zick, S. M., Djuric, Z., Ruffin, M. T., Litzinger, A. J., Normolle, D. P., Alrawi, S., Feng, M. R. & Brenner, D. E., Aug 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 8, p. 1930-1936 7 p.

    Research output: Contribution to journalArticle

    149 Scopus citations

    Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects

    Vareed, S. K., Kakarala, M., Ruffin, M. T., Crowell, J. A., Normolle, D. P., Djuric, Z. & Brenner, D. E., Jun 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 6, p. 1411-1417 7 p.

    Research output: Contribution to journalArticle

    272 Scopus citations

    Phase II study of the effects of ginger root extract on eicosanoids in colon mucosa in people at normal risk for colorectal cancer

    Zick, S. M., Turgeon, D. K., Vareed, S. K., Ruffin, M. T., Litzinger, A. J., Wright, B. D., Alrawi, S., Normolle, D. P., Djuric, Z. & Brenner, D. E., Nov 1 2011, In : Cancer Prevention Research. 4, 11, p. 1929-1937 9 p.

    Research output: Contribution to journalArticle

    30 Scopus citations

    Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting

    Zick, S. M., Ruffin, M. T., Lee, J., Normolle, D. P., Siden, R., Alrawi, S. & Brenner, D. E., May 1 2009, In : Supportive Care in Cancer. 17, 5, p. 563-572 10 p.

    Research output: Contribution to journalArticle

    92 Scopus citations

    Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancer

    Zick, S. M., Turgeon, D. K., Ren, J., Ruffin, M. T., Wright, B. D., Sen, A., Djuric, Z. & Brenner, D. E., Sep 1 2015, In : Molecular Carcinogenesis. 54, 9, p. 908-915 8 p.

    Research output: Contribution to journalArticle

    20 Scopus citations

    Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot

    Qiu, Y., Patwa, T. H., Xu, L., Shedden, K., Misek, D. E., Tuck, M., Jin, G., Ruffin, M. T., Turgeon, D. K., Synal, S., Bresalier, R., Marcon, N., Brenner, D. E. & Lubman, D. M., Apr 1 2008, In : Journal of Proteome Research. 7, 4, p. 1693-1703 11 p.

    Research output: Contribution to journalArticle

    143 Scopus citations
    111 Scopus citations

    Preference-based electronic decision aid to promote colorectal cancer screening: Results of a randomized controlled trial

    Ruffin, M., Fetters, M. D. & Jimbo, M., Oct 1 2007, In : Preventive Medicine. 45, 4, p. 267-273 7 p.

    Research output: Contribution to journalArticle

    76 Scopus citations
    6 Scopus citations

    Presence of human papillomavirus infection of the uterine cervix as determined by different detection methods in a low-risk community-based population.

    Zazove, P., Reed, B. D., Gregoire, L., Gorenflo, D. W., Lancaster, W. D., Ruffin, M. & Hruszczyk, J., Dec 1 1993, In : Archives of Family Medicine. 2, 12, p. 1250-1258 9 p.

    Research output: Contribution to journalArticle

    15 Scopus citations

    Prevention of cervix cancer

    Rock, C. L., Michael, C. W., Reynolds, R. K. & Ruffin, M., Jan 1 2000, In : Critical Reviews in Oncology/Hematology. 33, 3, p. 169-185 17 p.

    Research output: Contribution to journalArticle

    50 Scopus citations

    Primary care research funding sources

    Ruffin, M. & Sheets, K. J., Dec 1 1992, In : Journal of Family Practice. 35, 3, p. 281-287 7 p.

    Research output: Contribution to journalArticle

    13 Scopus citations

    Prompting primary care providers about increased patient risk as a result of family history: Does It work?

    Zazove, P., Plegue, M. A., Uhlmann, W. R. & Ruffin, M. T., May 1 2015, In : Journal of the American Board of Family Medicine. 28, 3, p. 334-342 9 p.

    Research output: Contribution to journalArticle

    9 Scopus citations

    Prostatic Alpha-Linolenic Acid (ALA) Is Positively Associated with Aggressive Prostate Cancer: A Relationship Which May Depend on Genetic Variation in ALA Metabolism

    Azrad, M., Zhang, K., Vollmer, R. T., Madden, J., Polascik, T. J., Snyder, D. C., Ruffin, M. T., Moul, J. W., Brenner, D., Hardy, R. W. & Demark-Wahnefried, W., Dec 28 2012, In : PloS one. 7, 12, e53104.

    Research output: Contribution to journalArticle

    11 Scopus citations

    Psychosocial factors in risk of cervical intraepithelial lesions

    Wilkerson, J. E., Bailey, J. M., Bieniasz, M. E., Murray, S. I. & Ruffin, M. T., Apr 1 2009, In : Journal of Women's Health. 18, 4, p. 513-518 6 p.

    Research output: Contribution to journalArticle

    5 Scopus citations

    Psychosocial predictors of adherence to risk-appropriate cervical cancer screening guidelines: A cross sectional study of women in Ohio Appalachia participating in the Community Awareness Resources and Education (CARE) project

    Paskett, E. D., McLaughlin, J. M., Reiter, P. L., Lehman, A. M., Rhoda, D. A., Katz, M. L., Hade, E. M., Post, D. M. & Ruffin, M. T., Jan 1 2010, In : Preventive Medicine. 50, 1-2, p. 74-80 7 p.

    Research output: Contribution to journalArticle

    47 Scopus citations

    Quantitation of 6-, 8- and 10-gingerols and 6-shogaol in human plasma by high performance liquid chromatography with electrochemical detection

    Zick, S. M., Ruffin, M. T., Djuric, Z., Normolle, D. & Brenner, D. E., Sep 1 2010, In : International Journal of Biomedical Science. 6, 3, p. 233-240 8 p.

    Research output: Contribution to journalArticle

    42 Scopus citations

    Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method

    Nie, S., Yin, H., Tan, Z., Anderson, M. A., Ruffin, M. T., Simeone, D. M. & Lubman, D. M., Dec 5 2014, In : Journal of Proteome Research. 13, 12, p. 6058-6066 9 p.

    Research output: Contribution to journalArticle

    16 Scopus citations

    Recommendations of the first Michigan conference on prostate cancer

    Porter, A. T., Zimmerman, J., Ruffin, M., Chernew, M., Callaghan, C., Davis, R., Lee, F., Montie, J., Swanson, G. M. & Oesterling, J. E., Oct 1996, In : Urology. 48, 4, p. 519-534 16 p.

    Research output: Contribution to journalArticle

    4 Scopus citations

    Recruitment and retention of economically underserved women to a cervical cancer prevention trial

    Bailey, J. M., Bieniasz, M. E., Kmak, D., Brenner, D. E. & Ruffin, M. T., Feb 2004, In : Applied Nursing Research. 17, 1, p. 55-60 6 p.

    Research output: Contribution to journalArticle

    29 Scopus citations

    Recruitment of minority and underserved populations in the United States: The centers for population health and health disparities experience

    Paskett, E. D., Reeves, K. W., McLaughlin, J. M., Katz, M. L., McAlearney, A. S., Ruffin, M. T., Halbert, C. H., Merete, C., Davis, F. & Gehlert, S., Nov 1 2008, In : Contemporary Clinical Trials. 29, 6, p. 847-861 15 p.

    Research output: Contribution to journalArticle

    107 Scopus citations

    Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: Comparison to fecal occult stool blood test

    Ruffin, M. T., Normolle, D. P., Evelegh, M. J., Baron, J. A., Bresalier, R. S., Marcon, N. E., Syngal, S., Turgeon, D. K., Tuck, M. K. & Brenner, D. E., Dec 1 2010, In : Cancer Biomarkers. 8, 2, p. 109-112 4 p.

    Research output: Contribution to journalArticle

    Relationships between serum and colon concentrations of carotenoids and fatty acids in randomized dietary intervention trial

    Sen, A., Ren, J., Ruffin, M. T., Turgeon, D. K., Brenner, D. E., Sidahmed, E., Rapai, M. E., Cornellier, M. L. & Djuric, Z., Jun 1 2013, In : Cancer Prevention Research. 6, 6, p. 558-565 8 p.

    Research output: Contribution to journalArticle

    18 Scopus citations

    Results of a Pilot Study of a Mail-Based Human Papillomavirus Self-Testing Program for Underscreened Women from Appalachian Ohio

    Reiter, P. L., Shoben, A. B., McDonough, D., Ruffin, M. T., Steinau, M., Unger, E. R., Paskett, E. D. & Katz, M. L., Mar 1 2019, In : Sexually transmitted diseases. 46, 3, p. 185-190 6 p.

    Research output: Contribution to journalArticle

    Screening for prostate cancer.

    Ruffin, M., Jan 1 1999, In : The Journal of family practice. 48, 8, p. 581-582 2 p.

    Research output: Contribution to journalArticle

    4 Scopus citations

    Selection criteria for breast cancer chemoprevention subjects

    Ruffin, M. T., August, D. A., Kelloff, G. J., Boone, C. W., Weber, B. L. & Brenner, D. E., 1993, In : Journal of cellular biochemistry. 53, S17G, p. 234-241 8 p.

    Research output: Contribution to journalArticle

    8 Scopus citations

    Spatial variation of the native colon microbiota in healthy adults

    Flynn, K. J., Ruffin, M. T., Kim Turgeon, D. & Schloss, P. D., Jul 2018, In : Cancer Prevention Research. 11, 7, p. 393-401 9 p.

    Research output: Contribution to journalArticle

    10 Scopus citations

    Suppression of human colorectal mucosal prostaglandins: Determining the lowest effective aspirin dose

    Ruffin IV, M. T., Krishnan, K., Rock, C. L., Normolle, D., Vaerten, M. A., Peters-Golden, M., Crowell, J., Kelloff, G., Boland, C. R. & Brenner, D. E., Aug 6 1997, In : Journal of the National Cancer Institute. 89, 15, p. 1152-1160 9 p.

    Research output: Contribution to journalArticle

    86 Scopus citations