Mack Ruffin, MD, MPH

    • 6089 Citations
    • 41 h-Index
    1977 …2021

    Research output per year

    If you made any changes in Pure these will be visible here soon.

    Research Output

    2014

    Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method

    Nie, S., Yin, H., Tan, Z., Anderson, M. A., Ruffin, M. T., Simeone, D. M. & Lubman, D. M., Dec 5 2014, In : Journal of Proteome Research. 13, 12, p. 6058-6066 9 p.

    Research output: Contribution to journalArticle

    16 Scopus citations

    Screening and prevention in primary care

    Ruffin, M. T. & Shultz, C. G., Jun 2014, In : Primary Care - Clinics in Office Practice. 41, 2, p. 17-18 2 p.

    Research output: Contribution to journalEditorial

    Screening strategies for colorectal cancer in asymptomatic adults

    Turgeon, D. K. & Ruffin, M. T., Jun 2014, In : Primary Care - Clinics in Office Practice. 41, 2, p. 331-353 23 p.

    Research output: Contribution to journalReview article

    1 Scopus citations

    The human gut microbiome as a screening tool for colorectal cancer

    Zackular, J. P., Rogers, M. A. M., Ruffin, M. T. & Schloss, P. D., Nov 1 2014, In : Cancer Prevention Research. 7, 11, p. 1112-1121 10 p.

    Research output: Contribution to journalArticle

    191 Scopus citations
    2013

    Clinical utility of HPV testing in cervical cancer screening

    Young, A. P., de la Cruz, M. S. D. & Ruffin, M., Jan 1 2013, Handbook on Human Papillomavirus: Prevalence, Detection and Management. Nova Science Publishers, Inc., p. 213-240 28 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Decision Aid to Technologically Enhance Shared decision making (DATES): Study protocol for a randomized controlled trial

    Jimbo, M., Kelly-Blake, K., Sen, A., Hawley, S. T. & Ruffin IV, M. T., Nov 11 2013, In : Trials. 14, 1, 381.

    Research output: Contribution to journalArticle

    7 Scopus citations

    Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer

    Jiang, Y., Turgeon, D. K., Wright, B. D., Sidahmed, E., Ruffin, M. T., Brenner, D. E., Sen, A. & Zick, S. M., Sep 1 2013, In : European Journal of Cancer Prevention. 22, 5, p. 455-460 6 p.

    Research output: Contribution to journalArticle

    23 Scopus citations

    Effects of ginger supplementation on cell-cycle biomarkers in the normal-appearing colonic mucosa of patients at increased risk for colorectal cancer: Results from a pilot, randomized, and controlled trial

    Citronberg, J., Bostick, R., Ahearn, T., Turgeon, D. K., Ruffin, M. T., Djuric, Z., Sen, A., Brenner, D. E. & Zick, S. M., Apr 1 2013, In : Cancer Prevention Research. 6, 4, p. 271-281 11 p.

    Research output: Contribution to journalArticle

    27 Scopus citations

    Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer

    Azrad, M., Vollmer, R. T., Madden, J., Dewhirst, M., Polascik, T. J., Snyder, D. C., Ruffin, M. T., Moul, J. W., Brenner, D. E. & Demark-Wahnefried, W., Apr 1 2013, In : Journal of Medicinal Food. 16, 4, p. 357-360 4 p.

    Research output: Contribution to journalArticle

    27 Scopus citations

    HPV Prevalence among Women from Appalachia: Results from the CARE Project

    Reiter, P. L., Katz, M. L., Ruffin, M. T., Hade, E. M., DeGraffenreid, C. R., Patel, D. A., Paskett, E. D. & Unger, E. R., Aug 30 2013, In : PloS one. 8, 8, e74276.

    Research output: Contribution to journalArticle

    10 Scopus citations

    Human papillomavirus (HPV) testing for normal cervical cytology in low-risk women aged 30-65 years by family physicians

    De La Cruz, M. S. D., Young, A. P. & Ruffin, M., Nov 1 2013, In : Journal of the American Board of Family Medicine. 26, 6, p. 720-727 8 p.

    Research output: Contribution to journalArticle

    2 Scopus citations

    Isobaric protein-level labeling strategy for serum glycoprotein quantification analysis by liquid chromatography-tandem mass spectrometry

    Nie, S., Lo, A., Zhu, J., Wu, J., Ruffin, M. T. & Lubman, D. M., Jun 4 2013, In : Analytical chemistry. 85, 11, p. 5353-5357 5 p.

    Research output: Contribution to journalArticle

    17 Scopus citations
    10 Scopus citations

    Relationships between serum and colon concentrations of carotenoids and fatty acids in randomized dietary intervention trial

    Sen, A., Ren, J., Ruffin, M. T., Turgeon, D. K., Brenner, D. E., Sidahmed, E., Rapai, M. E., Cornellier, M. L. & Djuric, Z., Jun 1 2013, In : Cancer Prevention Research. 6, 6, p. 558-565 8 p.

    Research output: Contribution to journalArticle

    18 Scopus citations

    Serum metabolomic analysis of pancreatic cancer-letter

    Shakour, S., Ruffin, M. T., Zick, S. M., Lubman, D. M. & Nie, S., Oct 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 10, 1 p.

    Research output: Contribution to journalLetter

    2 Scopus citations

    What is lacking in current decision aids on cancer screening?

    Jimbo, M., Rana, G. K., Hawley, S., Holmes-Rovner, M., Kelly-Blake, K., Nease, D. E. & Ruffin IV, M. T., May 1 2013, In : CA Cancer Journal for Clinicians. 63, 3, p. 193-214 22 p.

    Research output: Contribution to journalReview article

    43 Scopus citations
    2012

    Age-group differences in human papillomavirus types and cofactors for cervical intraepithelial neoplasia 3 among women referred to colposcopy

    Gargano, J. W., Nisenbaum, R., Lee, D. R., Ruffin, M., Steinau, M., Horowitz, I. R., Flowers, L. C., Tadros, T. S., Birdsong, G. & Unger, E. R., Jan 1 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 1, p. 111-121 11 p.

    Research output: Contribution to journalArticle

    14 Scopus citations

    A Mediterranean dietary intervention in persons at high risk of colon cancer: Recruitment and retention to an intensive study requiring biopsies

    Djuric, Z., Ruffin, M. T., Rapai, M. E., Cornellier, M. L., Ren, J., Ferreri, T. G., Askew, L. M., Sen, A., Brenner, D. E. & Turgeon, D. K., Sep 1 2012, In : Contemporary Clinical Trials. 33, 5, p. 881-888 8 p.

    Research output: Contribution to journalArticle

    11 Scopus citations

    An N-glycosylation analysis of human alpha-2-macroglobulin using an integrated approach

    Lin, Z., Lo, A., Simeone, D. M., Ruffin, M. T. & Lubman, D. M., May 1 2012, In : Journal of Proteomics and Bioinformatics. 5, 5, p. 127-134 8 p.

    Research output: Contribution to journalArticle

    28 Scopus citations

    Family history assessment: Impact on disease risk perceptions

    Wang, C., Sen, A., Ruffin, M. T., Nease, D. E., Gramling, R., Acheson, L. S., O'Neill, S. M. & Rubinstein, W. S., Oct 1 2012, In : American Journal of Preventive Medicine. 43, 4, p. 392-398 7 p.

    Research output: Contribution to journalArticle

    32 Scopus citations

    Health beliefs among individuals at increased familial risk for type 2 diabetes: Implications for prevention

    Dorman, J. S., Valdez, R., Liu, T., Wang, C., Rubinstein, W. S., O'Neill, S. M., Acheson, L. S., Ruffin, M. & Khoury, M. J., May 1 2012, In : Diabetes Research and Clinical Practice. 96, 2, p. 156-162 7 p.

    Research output: Contribution to journalArticle

    18 Scopus citations

    Human papillomavirus vaccine knowledge and hypothetical acceptance among women in Appalachia Ohio

    Ruffin, M., Hade, E. M., Gorsline, M. R., DeGraffinreid, C. R., Katz, M. L., Kobrin, S. C. & Paskett, E. D., Aug 3 2012, In : Vaccine. 30, 36, p. 5349-5357 9 p.

    Research output: Contribution to journalArticle

    7 Scopus citations

    Microsatellite instability and DNA mismatch repair protein deficiency in lynch syndrome colorectal polyps

    Yurgelun, M. B., Goel, A., Hornick, J. L., Sen, A., Turgeon, D. K., Ruffin IV, M. T., Marcon, N. E., Baron, J. A., Bresalier, R. S., Syngal, S., Brenner, D. E., Boland, C. R. & Stoffel, E. M., Apr 1 2012, In : Cancer Prevention Research. 5, 4, p. 574-582 9 p.

    Research output: Contribution to journalArticle

    69 Scopus citations

    National patterns in human papillomavirus vaccination: An analysis of the national survey of family growth

    Sadigh, G., Dempsey, A. F., Ruffin IV, M. T., Resnicow, K. & Carlos, R. C., Feb 2012, In : Human Vaccines and Immunotherapeutics. 8, 2, p. 234-242 9 p.

    Research output: Contribution to journalArticle

    14 Scopus citations

    Patterns of cellular and HPV 16 methylation as biomarkers for cervical neoplasia

    Patel, D. A., Rozek, L. S., Colacino, J. A., Van Zomeren-Dohm, A., Ruffin, M., Unger, E. R., Dolinoy, D. C., Swan, D. C., Onyekwuluje, J., DeGraffinreid, C. R. & Paskett, E. D., Sep 1 2012, In : Journal of Virological Methods. 184, 1-2, p. 84-92 9 p.

    Research output: Contribution to journalArticle

    18 Scopus citations

    Perceived risk of cervical cancer in appalachian women

    Kelly, K. M., Ferketich, A. K., Ruffin, M., Tatum, C. & Paskett, E. D., Nov 1 2012, In : American Journal of Health Behavior. 36, 6, p. 849-859 11 p.

    Research output: Contribution to journalReview article

    7 Scopus citations

    Prostatic Alpha-Linolenic Acid (ALA) Is Positively Associated with Aggressive Prostate Cancer: A Relationship Which May Depend on Genetic Variation in ALA Metabolism

    Azrad, M., Zhang, K., Vollmer, R. T., Madden, J., Polascik, T. J., Snyder, D. C., Ruffin, M. T., Moul, J. W., Brenner, D., Hardy, R. W. & Demark-Wahnefried, W., Dec 28 2012, In : PloS one. 7, 12, e53104.

    Research output: Contribution to journalArticle

    11 Scopus citations
    2011

    Clinical use of the Surgeon General's "my Family Health Portrait" (MFHP) tool: Opinions of future health care providers

    Owens, K. M., Marvin, M. L., Gelehrter, T. D., Ruffin, M. T. & Uhlmann, W. R., Oct 2011, In : Journal of Genetic Counseling. 20, 5, p. 510-525 16 p.

    Research output: Contribution to journalArticle

    17 Scopus citations

    Clinical utility of family history for cancer screening and referral in primary care: A report from the Family Healthware Impact Trial

    Rubinstein, W. S., Acheson, L. S., O'Neill, S. M., Ruffin, M. T., Wang, C., Beaumont, J. L. & Rothrock, N., Nov 1 2011, In : Genetics in Medicine. 13, 11, p. 956-965 10 p.

    Research output: Contribution to journalArticle

    55 Scopus citations

    Components of family history associated with women's disease perceptions for cancer: A report from the Family Healthware™ Impact Trial

    Rubinstein, W. S., O'Neill, S. M., Rothrock, N., Starzyk, E. J., Beaumont, J. L., Acheson, L. S., Wang, C., Gramling, R., Galliher, J. M. & Ruffin, M. T., Jan 1 2011, In : Genetics in Medicine. 13, 1, p. 52-62 11 p.

    Research output: Contribution to journalArticle

    15 Scopus citations

    Effect of low-fat diets on plasma levels of NF-κB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer

    Heymach, J. V., Shackleford, T. J., Tran, H. T., Yoo, S. Y., Do, K. A., Wergin, M., Saintigny, P., Vollmer, R. T., Polascik, T. J., Snyder, D. C., Ruffin IV, M. T., Yan, S., Dewhirst, M., Kunnumakkara, A. B., Aggarwal, B. B. & Demark-Wahnefried, W., Oct 1 2011, In : Cancer Prevention Research. 4, 10, p. 1590-1598 9 p.

    Research output: Contribution to journalArticle

    22 Scopus citations

    Effect of preventive messages tailored to family history on health behaviors: The family healthware impact trial

    Ruffin, M. T., Nease, D. E., Sen, A., Pace, W. D., Wang, C., Acheson, L. S., Rubinstein, W. S., O'Neill, S. & Gramling, R., Jan 1 2011, In : Annals of family medicine. 9, 1, p. 3-11 9 p.

    Research output: Contribution to journalArticle

    94 Scopus citations

    Lack of HPV 16 and 18 detection in serum of colposcopy clinic patients

    Patel, D. A., Unger, E. R., Walline, H., Opipari, A. W., Lee, D. R., Flowers, L. C. & Ruffin, M., Apr 1 2011, In : Journal of Clinical Virology. 50, 4, p. 342-344 3 p.

    Research output: Contribution to journalArticle

    1 Scopus citations

    Mass spectrometric assay for analysis of haptoglobin fucosylation in pancreatic cancer

    Lin, Z., Simeone, D. M., Anderson, M. A., Brand, R. E., Xie, X., Shedden, K. A., Ruffin, M. & Lubman, D. M., May 6 2011, In : Journal of Proteome Research. 10, 5, p. 2602-2611 10 p.

    Research output: Contribution to journalArticle

    58 Scopus citations

    Maternal characteristics that predict a preference for mandatory adolescent HPV vaccination

    Carlos, R. C., Dempsey, A. F., Resnicow, K., Ruffin, M., Patel, D. A., Straus, C. M. & Dalton, V. K., Feb 1 2011, In : Human Vaccines. 7, 2, p. 225-229 5 p.

    Research output: Contribution to journalArticle

    5 Scopus citations

    Phase II study of the effects of ginger root extract on eicosanoids in colon mucosa in people at normal risk for colorectal cancer

    Zick, S. M., Turgeon, D. K., Vareed, S. K., Ruffin, M. T., Litzinger, A. J., Wright, B. D., Alrawi, S., Normolle, D. P., Djuric, Z. & Brenner, D. E., Nov 1 2011, In : Cancer Prevention Research. 4, 11, p. 1929-1937 9 p.

    Research output: Contribution to journalArticle

    30 Scopus citations
    7 Scopus citations

    Worsening disparities in HPV vaccine utilization among 19-26 year old women

    Dempsey, A., Cohn, L., Dalton, V. & Ruffin, M., Jan 10 2011, In : Vaccine. 29, 3, p. 528-534 7 p.

    Research output: Contribution to journalArticle

    81 Scopus citations
    2010

    A randomized feasibility trial of brief telephone counseling to increase fruit and vegetable intakes

    Djuric, Z., Ellsworth, J. S., Ren, J., Sen, A. & Ruffin, M. T., May 1 2010, In : Preventive Medicine. 50, 5-6, p. 265-271 7 p.

    Research output: Contribution to journalArticle

    9 Scopus citations

    Family history and perceptions about risk and prevention for chronic diseases in primary care: A report from the family healthware™ impact trial

    Acheson, L. S., Wang, C., Zyzanski, S. J., Lynn, A., Ruffin, M. T., Gramling, R., Rubinstein, W. S., O'Neill, S. M. & Nease, D. E., Apr 1 2010, In : Genetics in Medicine. 12, 4, p. 212-218 7 p.

    Research output: Contribution to journalArticle

    51 Scopus citations

    Feasibility of using maternal cancer screening visits to identify adolescent girls eligible for human papillomavirus vaccination

    Carlos, R. C., Dempsey, A. F., Resnicow, K., Ruffin, M. T., Patel, D. A., Straus, C. M., Kure, A. & Dalton, V. K., Dec 1 2010, In : Journal of Women's Health. 19, 12, p. 2271-2275 5 p.

    Research output: Contribution to journalArticle

    2 Scopus citations

    Ohio Appalachian women's perceptions of the cost of cervical cancer screening

    McAlearney, A. S., Song, P. H., Rhoda, D. A., Tatum, C., Lemeshow, S., Ruffin, M., Phil Harrop, J. & Paskett, E. D., Dec 1 2010, In : Cancer. 116, 20, p. 4727-4734 8 p.

    Research output: Contribution to journalReview article

    5 Scopus citations

    Patient and clinic factors associated with adolescent human papillomavirus vaccine utilization within a university-based health system

    Dempsey, A., Cohn, L., Dalton, V. & Ruffin, M., Jan 22 2010, In : Vaccine. 28, 4, p. 989-995 7 p.

    Research output: Contribution to journalArticle

    77 Scopus citations

    Psychosocial predictors of adherence to risk-appropriate cervical cancer screening guidelines: A cross sectional study of women in Ohio Appalachia participating in the Community Awareness Resources and Education (CARE) project

    Paskett, E. D., McLaughlin, J. M., Reiter, P. L., Lehman, A. M., Rhoda, D. A., Katz, M. L., Hade, E. M., Post, D. M. & Ruffin, M. T., Jan 1 2010, In : Preventive Medicine. 50, 1-2, p. 74-80 7 p.

    Research output: Contribution to journalArticle

    47 Scopus citations

    Quantitation of 6-, 8- and 10-gingerols and 6-shogaol in human plasma by high performance liquid chromatography with electrochemical detection

    Zick, S. M., Ruffin, M. T., Djuric, Z., Normolle, D. & Brenner, D. E., Sep 1 2010, In : International Journal of Biomedical Science. 6, 3, p. 233-240 8 p.

    Research output: Contribution to journalArticle

    42 Scopus citations

    Rectal mucosal quantitative galactose oxidase-Schiff reaction as an early detection biomarker for colorectal cancer: Comparison to fecal occult stool blood test

    Ruffin, M. T., Normolle, D. P., Evelegh, M. J., Baron, J. A., Bresalier, R. S., Marcon, N. E., Syngal, S., Turgeon, D. K., Tuck, M. K. & Brenner, D. E., Dec 1 2010, In : Cancer Biomarkers. 8, 2, p. 109-112 4 p.

    Research output: Contribution to journalArticle

    2009

    Acceptance of the HPV vaccine among women, parents, community leaders, and healthcare providers in Ohio Appalachia

    Katz, M. L., Reiter, P. L., Heaner, S., Ruffin, M. T., Post, D. M. & Paskett, E. D., Jun 19 2009, In : Vaccine. 27, 30, p. 3945-3952 8 p.

    Research output: Contribution to journalArticle

    68 Scopus citations

    Comparison of risk perceptions and beliefs across common chronic diseases

    Wang, C., O'Neill, S. M., Rothrock, N., Gramling, R., Sen, A., Acheson, L. S., Rubinstein, W. S., Nease, D. E. & Ruffin, M., Feb 1 2009, In : Preventive Medicine. 48, 2, p. 197-202 6 p.

    Research output: Contribution to journalArticle

    79 Scopus citations

    Development and evaluation of a PCR and mass spectroscopy (PCR-MS)-based method for quantitative, type-specific detection of human papillomavirus

    Patel, D. A., Shih, Y. J., Newton, D. W., Michael, C. W., Oeth, P. A., Kane, M. D., Opipari, A. W., Ruffin, IV, M. T., Kalikin, L. M. & Kurnit, D. M., Sep 1 2009, In : Journal of Virological Methods. 160, 1-2, p. 78-84 7 p.

    Research output: Contribution to journalArticle

    15 Scopus citations
    39 Scopus citations