Mack Ruffin, MD, MPH

    • 5946 Citations
    • 40 h-Index
    1977 …2021
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    Research Output 1988 2019

    2009
    15 Citations (Scopus)

    Measuring cervical cancer risk: Development and validation of the CARE Risky Sexual Behavior Index

    Reiter, P. L., Katz, M. L., Ferketich, A. K., Ruffin, M. & Paskett, E. D., Dec 1 2009, In : Cancer Causes and Control. 20, 10, p. 1865-1871 7 p.

    Research output: Contribution to journalArticle

    Uterine Cervical Neoplasms
    Sexual Behavior
    Education
    Papanicolaou Test
    Research
    86 Citations (Scopus)

    Pancreatic cancer serum detection using a lectin/glyco-antibody array method

    Li, C., Simeone, D. M., Brenner, D. E., Anderson, M. A., Shedden, K. A., Ruffin, M. T. & Lubman, D. M., Feb 1 2009, In : Journal of Proteome Research. 8, 2, p. 483-492 10 p.

    Research output: Contribution to journalArticle

    Pancreatic Neoplasms
    Lectins
    Glycoproteins
    Microarrays
    Antibodies
    90 Citations (Scopus)

    Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting

    Zick, S. M., Ruffin, M., Lee, J., Normolle, D. P., Siden, R., Alrawi, S. & Brenner, D. E., May 1 2009, In : Supportive Care in Cancer. 17, 5, p. 563-572 10 p.

    Research output: Contribution to journalArticle

    Ginger
    Nausea
    Vomiting
    aprepitant
    Drug Therapy
    4 Citations (Scopus)

    Psychosocial factors in risk of cervical intraepithelial lesions

    Wilkerson, J. E., Bailey, J. M., Bieniasz, M. E., Murray, S. I. & Ruffin, M. T., Apr 1 2009, In : Journal of Women's Health. 18, 4, p. 513-518 6 p.

    Research output: Contribution to journalArticle

    Cell Biology
    Psychology
    Apgar Score
    Papanicolaou Test
    Checklist
    137 Citations (Scopus)

    Understanding the Reasons Why Mothers Do or Do Not Have Their Adolescent Daughters Vaccinated Against Human Papillomavirus

    Dempsey, A. F., Abraham, L. M., Dalton, V. & Ruffin, M., Aug 1 2009, In : Annals of Epidemiology. 19, 8, p. 531-538 8 p.

    Research output: Contribution to journalArticle

    Nuclear Family
    Mothers
    Vaccination
    Infection
    Interviews
    2008
    31 Citations (Scopus)

    Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying

    Stoffel, E. M., Turgeon, D. K., Stockwell, D. H., Normolle, D. P., Tuck, M. K., Marcon, N. E., Baron, J. A., Bresalier, R. S., Arber, N., Ruffin, M. T., Syngal, S. & Brenner, D. E., Dec 2008, In : Cancer Prevention Research. 1, 7, p. 507-513 7 p.

    Research output: Contribution to journalArticle

    Colonoscopy
    Adenoma
    Coloring Agents
    Polyps
    Adenomatous Polyps

    Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying.

    Stoffel, E. M., Turgeon, D. K., Stockwell, D. H., Normolle, D. P., Tuck, M. K., Marcon, N. E., Baron, J. A., Bresalier, R. S., Arber, N., Ruffin, M. T., Syngal, S. & Brenner, D. E., Dec 2008, In : Cancer Prevention Research. 1, 7, p. 507-513 7 p.

    Research output: Contribution to journalArticle

    Colonoscopy
    Adenoma
    Coloring Agents
    Polyps
    Adenomatous Polyps
    111 Citations (Scopus)

    Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery

    Demark-Wahnefried, W., Polascik, T. J., George, S. L., Switzer, B. R., Madden, J. F., Ruffin IV, M. T., Snyder, D. C., Owzar, K., Hars, V., Albala, D. M., Walther, P. J., Robertson, C. N., Moul, J. W., Dunn, B. K., Brenner, D., Minasian, L., Stella, P. & Vollmer, R. T., Dec 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 12, p. 3577-3587 11 p.

    Research output: Contribution to journalArticle

    Flax
    Dietary Fats
    Fat-Restricted Diet
    Prostatic Neoplasms
    Diet
    31 Citations (Scopus)

    Impact of a generalizable reminder system on colorectal cancer screening in diverse primary care practices: a report from the prompting and reminding at encounters for prevention project.

    Nease, D. E., Ruffin, M., Klinkman, M. S., Jimbo, M., Braun, T. M. & Underwood, J. M., Jan 1 2008, In : Medical Care. 46, 9 Suppl 1

    Research output: Contribution to journalArticle

    Reminder Systems
    Early Detection of Cancer
    Colorectal Neoplasms
    Primary Health Care
    Technology
    83 Citations (Scopus)

    Missed adenomas during colonoscopic surveillance in individuals with Lynch syndrome (hereditary nonpolyposis colorectal cancer)

    Stoffel, E. M., Kim Turgeon, D., Stockwell, D. H., Zhao, L., Normolle, D. P., Tuck, M. K., Bresalier, R. S., Marcon, N. E., Baron, J. A., Ruffin, M. T., Brenner, D. E. & Syngal, S., Nov 1 2008, In : Cancer Prevention Research. 1, 6, p. 470-475 6 p.

    Research output: Contribution to journalArticle

    Hereditary Nonpolyposis Colorectal Neoplasms
    Polyps
    Adenoma
    Colonoscopy
    Indigo Carmine
    15 Citations (Scopus)

    Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer

    Demark-Wahnefried, W., George, S. L., Switzer, B. R., Snyder, D. C., Madden, J. F., Polascik, T. J., Ruffin, M. T. & Vollmer, R. T., Dec 1 2008, In : Clinical Trials. 5, 3, p. 262-272 11 p.

    Research output: Contribution to journalArticle

    Flax
    Prostatic Neoplasms
    Randomized Controlled Trials
    Diet Therapy
    Neoplasms
    143 Citations (Scopus)

    Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthyhuman subjects

    Zick, S. M., Djuric, Z., Ruffin, M. T., Litzinger, A. J., Normolle, D. P., Alrawi, S., Feng, M. R. & Brenner, D. E., Aug 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 8, p. 1930-1936 7 p.

    Research output: Contribution to journalArticle

    Pharmacokinetics
    Sulfates
    Ginger
    Glucuronides
    gingerol
    260 Citations (Scopus)

    Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects

    Vareed, S. K., Kakarala, M., Ruffin, M. T., Crowell, J. A., Normolle, D. P., Djuric, Z. & Brenner, D. E., Jun 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 6, p. 1411-1417 7 p.

    Research output: Contribution to journalArticle

    Curcumin
    Healthy Volunteers
    Pharmacokinetics
    Sulfates
    Glucuronides
    143 Citations (Scopus)

    Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot

    Qiu, Y., Patwa, T. H., Xu, L., Shedden, K., Misek, D. E., Tuck, M., Jin, G., Ruffin, M. T., Turgeon, D. K., Synal, S., Bresalier, R., Marcon, N., Brenner, D. E. & Lubman, D. M., Apr 1 2008, In : Journal of Proteome Research. 7, 4, p. 1693-1703 11 p.

    Research output: Contribution to journalArticle

    Tumor Biomarkers
    Lectins
    Colorectal Neoplasms
    Glycoproteins
    Glycosylation
    105 Citations (Scopus)

    Recruitment of minority and underserved populations in the United States: The centers for population health and health disparities experience

    Paskett, E. D., Reeves, K. W., McLaughlin, J. M., Katz, M. L., McAlearney, A. S., Ruffin, M. T., Halbert, C. H., Merete, C., Davis, F. & Gehlert, S., Nov 1 2008, In : Contemporary Clinical Trials. 29, 6, p. 847-861 15 p.

    Research output: Contribution to journalArticle

    Vulnerable Populations
    Health Insurance Portability and Accountability Act
    Research Ethics Committees
    Health
    Research
    2007
    8 Citations (Scopus)

    Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cells

    Steinau, M., Rajeevan, M. S., Lee, D. R., Ruffin, M. T., Horowitz, I. R., Flowers, L. C., Tadros, T., Birdsong, G., Husain, M., Kmak, D. C., Longton, G. M., Vernon, S. D. & Unger, E. R., Feb 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 2, p. 295-301 7 p.

    Research output: Contribution to journalArticle

    RNA
    Colposcopy
    Early Detection of Cancer
    Uterine Cervical Neoplasms
    Genes
    76 Citations (Scopus)

    Preference-based electronic decision aid to promote colorectal cancer screening: Results of a randomized controlled trial

    Ruffin, M., Fetters, M. D. & Jimbo, M., Oct 1 2007, In : Preventive Medicine. 45, 4, p. 267-273 7 p.

    Research output: Contribution to journalArticle

    Decision Support Techniques
    Early Detection of Cancer
    Colorectal Neoplasms
    Randomized Controlled Trials
    Rural Population
    2006
    698 Citations (Scopus)

    Dose escalation of a curcuminoid formulation

    Lao, C. D., Ruffin IV, M. T., Normolle, D., Heath, D. D., Murray, S. I., Bailey, J. M., Boggs, M. E., Crowell, J., Rock, C. L. & Brenner, D. E., Mar 17 2006, In : BMC complementary and alternative medicine. 6, 10.

    Research output: Contribution to journalArticle

    Curcumin
    Curcuma
    Spices
    Southeastern Asia
    Maximum Tolerated Dose

    Human papillomaviruses

    Unger, E. R., Ruffin, M. & Diaz-Arrastia, C., Dec 1 2006, Clinical Gynecology. Elsevier Inc., p. 305-314 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    5 Citations (Scopus)

    Human papillomavirus in amniotic fluid

    Ruffin, M., Bailey, J. M., Roulston, D., Lee, D. R., Tucker, R. A., Swan, D. C. & Unger, E. R., Sep 4 2006, In : BMC Pregnancy and Childbirth. 6, 28.

    Research output: Contribution to journalArticle

    Amniotic Fluid
    Placenta
    Triplet Pregnancy
    Twin Pregnancy
    Amnion
    29 Citations (Scopus)

    Information technology and cancer prevention

    Jimbo, M., Nease, D. E., Ruffin IV, M. T. & Rana, G. K., Jan 1 2006, In : Ca-A Cancer Journal for Clinicians. 56, 1, p. 26-36 11 p.

    Research output: Contribution to journalReview article

    Technology
    Appointments and Schedules
    Neoplasms
    Primary Health Care
    Early Detection of Cancer
    2005
    13 Citations (Scopus)

    Challenges in herbal research: A randomized clinical trial to assess blinding with ginger

    Zick, S. M., Blume, A., Normolle, D. & Ruffin, M., Jun 1 2005, In : Complementary Therapies in Medicine. 13, 2, p. 101-106 6 p.

    Research output: Contribution to journalArticle

    Ginger
    Capsules
    Randomized Controlled Trials
    Research
    Placebos
    3 Citations (Scopus)

    Design of early validation trials of biomarkers

    Normolle, D., Ruffin IV, M. T. & Brenner, D., Dec 1 2005, In : Cancer Informatics. 1, 1, p. 25-31 7 p.

    Research output: Contribution to journalArticle

    Biomarkers
    Population
    Sensitivity and Specificity
    Mass Screening
    Health Services Needs and Demand
    53 Citations (Scopus)

    Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive women

    Rajeevan, M. S., Swan, D. C., Nisenbaum, R., Lee, D. R., Vernon, S. D., Ruffin, M. T., Horowitz, I. R., Flowers, L. C., Kmak, D., Tadros, T., Birdsong, G., Husain, M., Srivastava, S. & Unger, E. R., May 20 2005, In : International Journal of Cancer. 115, 1, p. 114-120 7 p.

    Research output: Contribution to journalArticle

    Epidemiologic Factors
    Human papillomavirus 16
    Viral Load
    Neoplasms
    Uterine Cervical Neoplasms
    20 Citations (Scopus)

    Gene expression profile of cervical tissue compared to exfoliated cells: Impact on biomarker discovery

    Steinau, M., Lee, D. R., Rajeevan, M. S., Vernon, S. D., Ruffin, M. T. & Unger, E. R., Jan 1 2005, In : BMC genomics. 6, 64.

    Research output: Contribution to journalArticle

    Transcriptome
    Biomarkers
    Genes
    Ubiquitin-Conjugating Enzymes
    Gene Expression
    2004
    120 Citations (Scopus)

    Adults' knowledge and behaviors related to human papillomavirus infection

    Holcomb, B., Bailey, J. M., Crawford, K. & Ruffin, M., Jan 1 2004, In : Journal of the American Board of Family Practice. 17, 1, p. 26-31 6 p.

    Research output: Contribution to journalArticle

    Papillomavirus Infections
    Family Physicians
    Risk-Taking
    Student Health Services
    Physicians' Offices
    3 Citations (Scopus)

    Colorectal cancer screening

    Nease, D. E., Stoffel, E., Turgeon, D. K. & Ruffin IV, M. T., Sep 1 2004, In : Clinics in Family Practice. 6, 3, p. 693-707 15 p.

    Research output: Contribution to journalReview article

    Early Detection of Cancer
    Colorectal Neoplasms
    Neoplasms
    Technology
    Population
    11 Citations (Scopus)

    Developing a web site in primary care

    Fetters, M. D., Ivankova, N. V., Ruffin, M., Creswell, J. W. & Power, D., Oct 1 2004, In : Family medicine. 36, 9, p. 651-659 9 p.

    Research output: Contribution to journalArticle

    Colorectal Neoplasms
    Primary Health Care
    Focus Groups
    Early Detection of Cancer
    Interviews
    1 Citation (Scopus)

    Effects of low dose aspirin (81 mg) on proliferating cell nuclear antigen and Amaranthus caudatus labeling in normal-risk and high-risk human subjects for colorectal cancer

    Krishnan, K., Aoki, T., Ruffin, M. T., Normolle, D. P., Boland, C. R. & Brenner, D. E., Apr 20 2004, In : Cancer detection and prevention. 28, 2, p. 107-113 7 p.

    Research output: Contribution to journalArticle

    Amaranthus
    Proliferating Cell Nuclear Antigen
    Aspirin
    Colorectal Neoplasms
    Agglutinins
    1 Citation (Scopus)

    Human Papillomavirus Infection in Men and Women: The Impact of Nutrition on Cervical Cancer

    Ruffin, M. T. & Rock, C. L., Dec 1 2004, Principles of Gender-Specific Medicine. Elsevier Inc., Vol. 2. p. 796-812 17 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Papillomavirus Infections
    Nutrition
    Uterine Cervical Neoplasms
    Epidemiology
    Micronutrients
    1 Citation (Scopus)

    Increasing cancer screening rates in primary care: No easy solutions

    Ruffin, M., Gorenflo, D. W. & Murff, H. J., Dec 2004, In : Journal of Clinical Outcomes Management. 11, 12, p. 754-755 2 p.

    Research output: Contribution to journalShort survey

    Early Detection of Cancer
    Primary Health Care
    18 Citations (Scopus)

    Interventions fail to increase cancer screening rates in community-based primary care practices

    Ruffin, M. & Gorenflo, D. W., Sep 1 2004, In : Preventive Medicine. 39, 3, p. 435-440 6 p.

    Research output: Contribution to journalArticle

    Early Detection of Cancer
    Primary Health Care
    Papanicolaou Test
    Sigmoidoscopy
    Occult Blood
    23 Citations (Scopus)

    Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III

    Ruffin, M., Bailey, J. M., Normolle, D. P., Michael, C. W., Bieniasz, M. E., Kmak, D. C., Unger, E. R. & Brenner, D. E., Dec 1 2004, In : Cancer Epidemiology Biomarkers and Prevention. 13, 12, p. 2148-2152 5 p.

    Research output: Contribution to journalArticle

    Cervical Intraepithelial Neoplasia
    Tretinoin
    Placebos
    Female Contraceptive Devices
    Biopsy
    29 Citations (Scopus)

    Recruitment and retention of economically underserved women to a cervical cancer prevention trial

    Bailey, J. M., Bieniasz, M. E., Kmak, D., Brenner, D. E. & Ruffin, M. T., Feb 2004, In : Applied Nursing Research. 17, 1, p. 55-60 6 p.

    Research output: Contribution to journalArticle

    Uterine Cervical Neoplasms
    Nurse Practitioners
    Creativity
    Vulnerable Populations
    Child Care
    2003
    8 Citations (Scopus)

    Chaperone use by family physicians during the collection of a Pap smear.

    Rockwell, P., Steyer, T. E. & Ruffin, M. T., Jan 1 2003, In : Annals of family medicine. 1, 4, p. 218-220 3 p.

    Research output: Contribution to journalArticle

    Papanicolaou Test
    Family Physicians
    Physicians
    Gynecological Examination
    Surveys and Questionnaires
    6 Citations (Scopus)

    Family physicians' knowledge of risk factors for cervical cancer

    Ruffin IV, M. T., Jan 1 2003, In : Journal of Women's Health. 12, 6, p. 561-567 7 p.

    Research output: Contribution to journalArticle

    Family Physicians
    Uterine Cervical Neoplasms
    Physicians
    Papanicolaou Test
    Geographic Locations
    1 Citation (Scopus)

    Women's feedback on a chemopreventive trial for cervical dysplasia

    Bieniasz, M. E., Underwood, D., Bailey, J. & Ruffin IV, M. T., Feb 1 2003, In : Applied Nursing Research. 16, 1, p. 22-28 7 p.

    Research output: Contribution to journalReview article

    Uterine Cervical Dysplasia
    Chemoprevention
    Research Personnel
    Clinical Trials
    Interviews
    2001
    31 Citations (Scopus)

    Colonic mucosal prostaglandin e2 and cyclooxygenase expression before and after low aspirin doses in subjects at high risk or at normal risk for colorectal cancer1, 2

    Krishnan, K., Ruffin, M. T., Normolle, D., Shureiqi, I., Burney, K., Bailey, J., Peters-Golden, M., Rock, C. L., Boland, C. R. & Brenner, D. E., Jan 1 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 5, p. 447-453 7 p.

    Research output: Contribution to journalArticle

    Prostaglandin-Endoperoxide Synthases
    Dinoprostone
    Aspirin
    Colorectal Neoplasms
    Biomarkers
    10 Citations (Scopus)

    Do antioxidants still have a role in the prevention of human cancer?

    Ruffin, M. & Rock, C. L., Jan 1 2001, In : Current Oncology Reports. 3, 4, p. 306-313 8 p.

    Research output: Contribution to journalReview article

    Antioxidants
    Micronutrients
    Neoplasms
    Carotenoids
    Selenium
    32 Citations (Scopus)

    High vegetable and fruit diet intervention in premenopausal women with cervical intraepithelial neoplasia

    Rock, C. L., Moskowitz, A., Huizar, B., Saenz, C. C., Clark, J. T., Daly, T. L., Chin, H., Behling, C. & Ruffin IV, M. T., Jan 1 2001, In : Journal of the American Dietetic Association. 101, 10, p. 1167-1174 8 p.

    Research output: Contribution to journalArticle

    Cervical Intraepithelial Neoplasia
    homocysteine
    Vegetables
    Fruit
    carotenoids
    2000
    27 Citations (Scopus)

    Chemoprevention for colorectal cancer

    Krishnan, K., Ruffin, M. & Brenner, D. E., Jan 1 2000, In : Critical Reviews in Oncology/Hematology. 33, 3, p. 199-219 21 p.

    Research output: Contribution to journalArticle

    Neoplastic Cell Transformation
    Precancerous Conditions
    Anticarcinogenic Agents
    Colonic Polyps
    Cultured Tumor Cells
    78 Citations (Scopus)

    Genetic taste markers and preferences for vegetables and fruit of female breast care patients

    Drewnowski, A., Henderson, S. A., Hann, C. S., Berg, W. A. & Ruffin, M. T., Feb 2000, In : Journal of the American Dietetic Association. 100, 2, p. 191-197 7 p.

    Research output: Contribution to journalArticle

    propylthiouracil
    Propylthiouracil
    patient care
    Genetic Markers
    Vegetables
    111 Citations (Scopus)
    Uterine Cervical Neoplasms
    Colorectal Neoplasms
    Prostatic Neoplasms
    Primary Health Care
    Early Detection of Cancer
    50 Citations (Scopus)

    Prevention of cervix cancer

    Rock, C. L., Michael, C. W., Reynolds, R. K. & Ruffin, M., Jan 1 2000, In : Critical Reviews in Oncology/Hematology. 33, 3, p. 169-185 17 p.

    Research output: Contribution to journalArticle

    Uterine Cervical Neoplasms
    Carcinoma
    Cervix Uteri
    Papanicolaou Test
    Papillomavirus Vaccines
    14 Citations (Scopus)

    Recruiting subjects in cancer prevention and control studies

    Ruffin, M. & Baron, J., Apr 11 2000, In : Journal of cellular biochemistry. 77, SUPPL. 34, p. 80-83 4 p.

    Research output: Contribution to journalReview article

    Workload
    Health care
    Healthy Volunteers
    Research Personnel
    Delivery of Health Care
    1999
    24 Citations (Scopus)

    Age and food preferences influence dietary intakes of breast care patients

    Drewnowski, A., Henderson, S. A., Hann, C. S., Barratt-Fornell, A. & Ruffin, M., Nov 1 1999, In : Health Psychology. 18, 6, p. 570-578 9 p.

    Research output: Contribution to journalArticle

    Food Preferences
    Patient Care
    Breast
    Fats
    Propylthiouracil
    4 Citations (Scopus)

    Screening for prostate cancer.

    Ruffin, M., Jan 1 1999, In : The Journal of family practice. 48, 8, p. 581-582 2 p.

    Research output: Contribution to journalArticle

    Mass Screening
    Quebec
    Prostate-Specific Antigen
    Reproducibility of Results
    Prostatic Neoplasms
    23 Citations (Scopus)

    The psychosexual impact of human papillomavirus cervical infections

    Reed, B. D., Ruffin IV, M. T., Gorenflo, D. W. & Zazove, P., Feb 1999, In : Journal of Family Practice. 48, 2, p. 110-116 7 p.

    Research output: Contribution to journalArticle

    Papillomavirus Infections
    Sexually Transmitted Diseases
    Bacterial Sexually Transmitted Diseases
    Vaginitis
    Colposcopy
    1998
    10 Citations (Scopus)

    Applicability of clinical trial results to primary care (multiple letters) [4]

    Sonis, J., Doukas, D., Klinkman, M., Reed, B., Ruffin, M., Guyatt, G. H., Dans, A. L., Dans, L. F. & Richardson, S., Nov 25 1998, In : JAMA - Journal of the American Medical Association. 280, 20, p. 1746 1 p.

    Research output: Contribution to journalLetter

    Family Practice
    Evidence-Based Medicine
    Primary Health Care
    Clinical Trials
    197 Citations (Scopus)

    Bioavailability of β-carotene is lower in raw than in processed carrots and spinach in women

    Rock, C. L., Lovalvo, J. L., Emenhiser, C., Ruffin, M., Flatt, S. W. & Schwartz, S. J., May 1 1998, In : Journal of Nutrition. 128, 5, p. 913-916 4 p.

    Research output: Contribution to journalArticle

    Daucus carota
    Spinacia oleracea
    Carotenoids
    carotenes
    spinach