Mack Ruffin, MD, MPH

    • 6149 Citations
    • 41 h-Index
    1988 …2020

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    2019

    Fecal short-chain fatty acids are not predictive of colonic tumor status and cannot be predicted based on bacterial community structure

    Sze, M. A., Topçuoğlu, B. D., Lesniak, N. A., Ruffin, M. T. & Schloss, P. D., Jul 1 2019, In : mBio. 10, 4, e01454-19.

    Research output: Contribution to journalArticle

    Open Access
    2 Scopus citations

    Increases in colonic bacterial diversity after ω-3 fatty acid supplementation predict decreased colonic prostaglandin E2 concentrations in healthy adults

    Djuric, Z., Bassis, C. M., Plegue, M. A., Sen, A., Turgeon, D. K., Herman, K., Young, V. B., Brenner, D. E. & Ruffin, M. T., Jan 1 2019, In : Journal of Nutrition. 149, 7, p. 1170-1179 10 p.

    Research output: Contribution to journalArticle

    2 Scopus citations

    Inherited alterations of TGF beta signaling components in Appalachian cervical cancers

    Knobloch, T. J., Peng, J., Hade, E. M., Cohn, D. E., Ruffin, M. T., Schiano, M. A., Calhoun, B. C., McBee, W. C., Lesnock, J. L., Gallion, H. H., Pollock, J., Lu, B., Oghumu, S., Zhang, Z., Sears, M. T., Ogbemudia, B. E., Perrault, J. T., Weghorst, L. C., Strawser, E., DeGraffinreid, C. R. & 2 others, Paskett, E. D. & Weghorst, C. M., Oct 1 2019, In : Cancer Causes and Control. 30, 10, p. 1087-1100 14 p.

    Research output: Contribution to journalArticle

    1 Scopus citations

    Interactivity in a Decision Aid: Findings From a Decision Aid to Technologically Enhance Shared Decision Making RCT

    Jimbo, M., Sen, A., Plegue, M. A., Hawley, S., Kelly-Blake, K., Rapai, M., Zhang, M., Zhang, Y., Xie, X. & Ruffin, M. T., Jul 2019, In : American Journal of Preventive Medicine. 57, 1, p. 77-86 10 p.

    Research output: Contribution to journalArticle

    Results of a Pilot Study of a Mail-Based Human Papillomavirus Self-Testing Program for Underscreened Women from Appalachian Ohio

    Reiter, P. L., Shoben, A. B., McDonough, D., Ruffin, M. T., Steinau, M., Unger, E. R., Paskett, E. D. & Katz, M. L., Mar 1 2019, In : Sexually transmitted diseases. 46, 3, p. 185-190 6 p.

    Research output: Contribution to journalArticle

    Using pharmacogenomic testing in primary care: Protocol for a pilot randomized controlled study

    Mitrzyk, B. M., Kadri, R., Farris, K. B., Ellingrod, V. L., Klinkman, M. S., Ruffin, M. T., Plegue, M. A. & Buis, L. R., Jan 1 2019, In : Journal of medical Internet research. 21, 8, e13848.

    Research output: Contribution to journalArticle

    Open Access
    2018

    A web-based decision tool to improve contraceptive counseling for women with chronic medical conditions: Protocol for a mixed methods implementation study

    Wu, J. P., Damschroder, L. J., Fetters, M. D., Zikmund-Fisher, B. J., Crabtree, B. F., Hudson, S. V., Ruffin, M. T., Fucinari, J., Kang, M., Susan Taichman, L. & Creswell, J. W., Apr 2018, In : Journal of medical Internet research. 20, 4, e107.

    Research output: Contribution to journalArticle

    1 Scopus citations

    Colonic Mucosal Bacteria Are Associated with Inter-Individual Variability in Serum Carotenoid Concentrations

    Djuric, Z., Bassis, C. M., Plegue, M. A., Ren, J., Chan, R., Sidahmed, E. K., Turgeon, D. K., Ruffin, M. T., Kato, I. & Sen, A., Apr 2018, In : Journal of the Academy of Nutrition and Dietetics. 118, 4, p. 606-616.e3

    Research output: Contribution to journalArticle

    4 Scopus citations

    Diagnostic potential and interactive dynamics of the colorectal cancer virome

    Hannigan, G. D., Duhaime, M. B., Ruffin, M. T., Koumpouras, C. C. & Schloss, P. D., Nov 1 2018, In : mBio. 9, 6, e02248-18.

    Research output: Contribution to journalArticle

    25 Scopus citations

    Effects of an Education Intervention about HPV Self-Testing for Healthcare Providers and Staff

    Presser, B. E., Katz, M. L., Shoben, A. B., Moore, D., Ruffin, M. T., Paskett, E. D. & Reiter, P. L., Oct 1 2018, In : Journal of Cancer Education. 33, 5, p. 954-959 6 p.

    Research output: Contribution to journalArticle

    3 Scopus citations

    Spatial variation of the native colon microbiota in healthy adults

    Flynn, K. J., Ruffin, M. T., Kim Turgeon, D. & Schloss, P. D., Jul 2018, In : Cancer Prevention Research. 11, 7, p. 393-401 9 p.

    Research output: Contribution to journalArticle

    10 Scopus citations
    2017

    Correlates of Patient Intent and Preference on Colorectal Cancer Screening

    Jimbo, M., Sen, A., Plegue, M. A., Hawley, S. T., Kelly-Blake, K., Rapai, M., Zhang, M., Zhang, Y. & Ruffin, M. T., Apr 1 2017, In : American Journal of Preventive Medicine. 52, 4, p. 443-450 8 p.

    Research output: Contribution to journalArticle

    3 Scopus citations

    Direct-to-consumer genetic testing: User motivations, decision making, and perceived utility of results

    Roberts, J. S., Gornick, M. C., Carere, D. A., Uhlmann, W. R., Ruffin, M. T. & Green, R. C., Jun 1 2017, In : Public health genomics. 20, 1, p. 36-45 10 p.

    Research output: Contribution to journalArticle

    37 Scopus citations

    Normalization of the microbiota in patients after treatment for colonic lesions

    Sze, M. A., Baxter, N. T., Ruffin, M. T., Rogers, M. A. M. & Schloss, P. D., Nov 16 2017, In : Microbiome. 5, 1, 1 p.

    Research output: Contribution to journalArticle

    12 Scopus citations

    Personal genomic testing for cancer risk: Results from the impact of personal genomics study

    Gray, S. W., Gollust, S. E., Carere, D. A., Chen, C. A., Cronin, A., Kalia, S. S., Rana, H. Q., Ruffin Iv, M. T., Wang, C., Roberts, J. S. & Green, R. C., Feb 20 2017, In : Journal of Clinical Oncology. 35, 6, p. 636-644 9 p.

    Research output: Contribution to journalArticle

    15 Scopus citations
    6 Scopus citations

    The anti-inflammatory effect of personalized omega-3 fatty acid dosing for reducing prostaglandin E2 in the colonic mucosa is attenuated in obesity

    Djuric, Z., Turgeon, D. K., Sen, A., Ren, J., Herman, K., Ramaswamy, D., Zhao, L., Ruffin, M. T., Normolle, D. P., Smith, W. L. & Brenner, D. E., Dec 1 2017, In : Cancer Prevention Research. 10, 12, p. 729-737 9 p.

    Research output: Contribution to journalArticle

    6 Scopus citations

    The Effect of Perceived Stress on Epstein-Barr Virus Antibody Titers in Appalachian Ohio Women

    Brook, M. J., Christian, L. M., Hade, E. M. & Ruffin, M. T., Oct 1 2017, In : NeuroImmunoModulation. 24, 2, p. 67-73 7 p.

    Research output: Contribution to journalArticle

    2 Scopus citations
    2016

    Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue

    Sidahmed, E. K., Sen, A., Ren, J., Patel, A., Turgeon, D. K., Ruffin, M. T., Brenner, D. E. & Djuric, Z., Oct 2 2016, In : Nutrition and cancer. 68, 7, p. 1192-1201 10 p.

    Research output: Contribution to journalArticle

    6 Scopus citations

    Consumer perceptions of interactions with primary care providers after direct-to-consumer personal genomic testing

    for the Impact of Personal Genomics Study Group, Apr 19 2016, In : Annals of internal medicine. 164, 8, p. 513-522 10 p.

    Research output: Contribution to journalArticle

    53 Scopus citations

    Implications of personal genomic testing for health behaviors: The case of smoking

    PGen Study Group, Jan 1 2016, In : Nicotine and Tobacco Research. 18, 12, p. 2273-2277 5 p.

    Research output: Contribution to journalArticle

    5 Scopus citations

    Markers of systemic exposures to products of intestinal bacteria in a dietary intervention study

    Umoh, F. I., Kato, I., Ren, J., Wachowiak, P. L., Ruffin, M. T., Turgeon, D. K., Sen, A., Brenner, D. E. & Djuric, Z., Mar 1 2016, In : European Journal of Nutrition. 55, 2, p. 793-798 6 p.

    Research output: Contribution to journalArticle

    13 Scopus citations

    Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions

    Baxter, N. T., Ruffin, M. T., Rogers, M. A. M. & Schloss, P. D., Apr 6 2016, In : Genome Medicine. 8, 1, 37.

    Research output: Contribution to journalArticle

    77 Scopus citations
    2015

    Disparate results between proliferation rates of surgically excised prostate tumors and an in vitro bioassay using sera from a positive randomized controlled trial

    Azrad, M., Vollmer, R. T., Madden, J., Polascik, T. J., Snyder, D. C., Ruffin, M. T., Moul, J. W., Brenner, D., He, X. & Demark-Wahnefried, W., Apr 1 2015, In : Biotechnic and Histochemistry. 90, 3, p. 184-189 6 p.

    Research output: Contribution to journalArticle

    2 Scopus citations

    Effects of a Mediterranean Diet Intervention on Anti- and Pro-Inflammatory Eicosanoids, Epithelial Proliferation, and Nuclear Morphology in Biopsies of Normal Colon Tissue

    Djuric, Z., Turgeon, D. K., Ren, J., Neilson, A., Plegue, M., Waters, I. G., Chan, A., Askew, L. M., Ruffin, M., Sen, A. & Brenner, D. E., Jul 4 2015, In : Nutrition and cancer. 67, 5, p. 721-729 9 p.

    Research output: Contribution to journalArticle

    6 Scopus citations

    Effects of vitamin E from supplements and diet on colonic α-and γ-tocopherol concentrations in persons at increased colon cancer risk

    Li, Y., Sen, A., Ren, J., Askew, L. M., Sidahmed, E., Brenner, D. E., Ruffin, M. T., Turgeon, D. K. & Djuric, Z., Jan 2 2015, In : Nutrition and cancer. 67, 1, p. 73-81 9 p.

    Research output: Contribution to journalArticle

    7 Scopus citations

    How Well Do Customers of Direct-to-Consumer Personal Genomic Testing Services Comprehend Genetic Test Results? Findings from the Impact of Personal Genomics Study for the PGen Study Group

    Ostergren, J. E., Gornick, M. C., Carere, D. A., Kalia, S. S., Uhlmann, W. R., Ruffin, M. T., Mountain, J. L., Green, R. C. & Roberts, J. S., Jul 25 2015, In : Public health genomics. 18, 4, p. 216-224 9 p.

    Research output: Contribution to journalArticle

    44 Scopus citations

    Impact of an electronic health record (EHR) reminder on human papillomavirus (HPV) vaccine initiation and timely completion

    Ruffin, M. T., Plegue, M. A., Rockwell, P. G., Young, A. P., Patel, D. A. & Yeazel, M. W., May 1 2015, In : Journal of the American Board of Family Medicine. 28, 3, p. 324-333 10 p.

    Research output: Contribution to journalArticle

    33 Scopus citations

    Impact of cervical cancer screening guidelines on screening for chlamydia

    Ursu, A., Sen, A. & Ruffin, M., Jan 1 2015, In : Annals of family medicine. 13, 4, p. 361-363 3 p.

    Research output: Contribution to journalArticle

    8 Scopus citations

    Impact of family history assessment on communication with family members and health care providers: A report from the Family Healthware™ Impact Trial (FHITr)

    Family Healthware™ Impact Trial (FHITr) Group, Aug 1 2015, In : Preventive Medicine. 77, p. 28-34 7 p.

    Research output: Contribution to journalArticle

    14 Scopus citations

    Large-scale identification of core-fucosylated glycopeptide sites in pancreatic cancer serum using mass spectrometry

    Tan, Z., Yin, H., Nie, S., Lin, Z., Zhu, J., Ruffin, M. T., Anderson, M. A., Simeone, D. M. & Lubman, D. M., Apr 3 2015, In : Journal of Proteome Research. 14, 4, p. 1968-1978 11 p.

    Research output: Contribution to journalArticle

    43 Scopus citations

    Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancer

    Zick, S. M., Turgeon, D. K., Ren, J., Ruffin, M. T., Wright, B. D., Sen, A., Djuric, Z. & Brenner, D. E., Sep 1 2015, In : Molecular Carcinogenesis. 54, 9, p. 908-915 8 p.

    Research output: Contribution to journalArticle

    20 Scopus citations

    Prompting primary care providers about increased patient risk as a result of family history: Does It work?

    Zazove, P., Plegue, M. A., Uhlmann, W. R. & Ruffin, M. T., May 1 2015, In : Journal of the American Board of Family Medicine. 28, 3, p. 334-342 9 p.

    Research output: Contribution to journalArticle

    9 Scopus citations
    2014

    Communication preference moderates the effect of a tailored intervention to increase colorectal cancer screening among African Americans

    Resnicow, K., Zhou, Y., Hawley, S., Jimbo, M., Ruffin, M. T., Davis, R. E., Shires, D. & Lafata, J. E., Dec 1 2014, In : Patient Education and Counseling. 97, 3, p. 370-375 6 p.

    Research output: Contribution to journalArticle

    Communication preference moderates the effect of a tailored intervention to increase colorectal cancer screening among African Americans

    Resnicow, K., Zhou, Y., Hawley, S., Jimbo, M., Ruffin, M. T., Davis, R. E., Shires, D. & Lafata, J. E., Dec 1 2014, In : Patient Education and Counseling. 97, 3, p. 370-375 6 p.

    Research output: Contribution to journalArticle

    11 Scopus citations
    27 Scopus citations

    Development and initial feedback about a human papillomavirus (HPV) vaccine comic book for adolescents

    Katz, M. L., Oldach, B. R., Goodwin, J., Reiter, P. L., Ruffin, M. T. & Paskett, E. D., Jun 2014, In : Journal of Cancer Education. 29, 2, p. 318-324 7 p.

    Research output: Contribution to journalArticle

    7 Scopus citations

    Development of exchange lists for Mediterranean and Healthy Eating Diets: Implementation in an intervention trial

    Sidahmed, E., Cornellier, M. L., Ren, J., Askew, L. M., Li, Y., Talaat, N., Rapai, M. S., Ruffin, M. T., Turgeon, D. K., Brenner, D., Sen, A. & Djuric, Z., Oct 1 2014, In : Journal of Human Nutrition and Dietetics. 27, 5, p. 413-425 13 p.

    Research output: Contribution to journalArticle

    10 Scopus citations

    Diagnosis and management of pancreatic cancer

    De La Cruz, M. S. D., Young, A. P. & Ruffin IV, M. T., Apr 15 2014, In : American family physician. 89, 8, p. 626-632 7 p.

    Research output: Contribution to journalArticle

    34 Scopus citations

    Glycoprotein biomarker panel for pancreatic cancer discovered by quantitative proteomics analysis

    Nie, S., Lo, A., Wu, J., Zhu, J., Tan, Z., Simeone, D. M., Anderson, M. A., Shedden, K. A., Ruffin, M. T. & Lubman, D. M., Apr 4 2014, In : Journal of Proteome Research. 13, 4, p. 1873-1884 12 p.

    Research output: Contribution to journalArticle

    67 Scopus citations

    Label-free relative quantification of alpha-2-macroglobulin site-specific core-fucosylation in pancreatic cancer by LC-MS/MS

    Lin, Z., Yin, H., Lo, A., Ruffin, M. T., Anderson, M. A., Simeone, D. M. & Lubman, D. M., Aug 2014, In : ELECTROPHORESIS. 35, 15, p. 2108-2115 8 p.

    Research output: Contribution to journalArticle

    17 Scopus citations

    Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method

    Nie, S., Yin, H., Tan, Z., Anderson, M. A., Ruffin, M. T., Simeone, D. M. & Lubman, D. M., Dec 5 2014, In : Journal of Proteome Research. 13, 12, p. 6058-6066 9 p.

    Research output: Contribution to journalArticle

    16 Scopus citations

    The human gut microbiome as a screening tool for colorectal cancer

    Zackular, J. P., Rogers, M. A. M., Ruffin, M. T. & Schloss, P. D., Nov 1 2014, In : Cancer Prevention Research. 7, 11, p. 1112-1121 10 p.

    Research output: Contribution to journalArticle

    206 Scopus citations
    2013

    Decision Aid to Technologically Enhance Shared decision making (DATES): Study protocol for a randomized controlled trial

    Jimbo, M., Kelly-Blake, K., Sen, A., Hawley, S. T. & Ruffin IV, M. T., Nov 11 2013, In : Trials. 14, 1, 381.

    Research output: Contribution to journalArticle

    7 Scopus citations

    Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer

    Jiang, Y., Turgeon, D. K., Wright, B. D., Sidahmed, E., Ruffin, M. T., Brenner, D. E., Sen, A. & Zick, S. M., Sep 1 2013, In : European Journal of Cancer Prevention. 22, 5, p. 455-460 6 p.

    Research output: Contribution to journalArticle

    23 Scopus citations

    Effects of ginger supplementation on cell-cycle biomarkers in the normal-appearing colonic mucosa of patients at increased risk for colorectal cancer: Results from a pilot, randomized, and controlled trial

    Citronberg, J., Bostick, R., Ahearn, T., Turgeon, D. K., Ruffin, M. T., Djuric, Z., Sen, A., Brenner, D. E. & Zick, S. M., Apr 1 2013, In : Cancer Prevention Research. 6, 4, p. 271-281 11 p.

    Research output: Contribution to journalArticle

    27 Scopus citations

    Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer

    Azrad, M., Vollmer, R. T., Madden, J., Dewhirst, M., Polascik, T. J., Snyder, D. C., Ruffin, M. T., Moul, J. W., Brenner, D. E. & Demark-Wahnefried, W., Apr 1 2013, In : Journal of Medicinal Food. 16, 4, p. 357-360 4 p.

    Research output: Contribution to journalArticle

    27 Scopus citations

    HPV Prevalence among Women from Appalachia: Results from the CARE Project

    Reiter, P. L., Katz, M. L., Ruffin, M. T., Hade, E. M., DeGraffenreid, C. R., Patel, D. A., Paskett, E. D. & Unger, E. R., Aug 30 2013, In : PloS one. 8, 8, e74276.

    Research output: Contribution to journalArticle

    12 Scopus citations

    Human papillomavirus (HPV) testing for normal cervical cytology in low-risk women aged 30-65 years by family physicians

    De La Cruz, M. S. D., Young, A. P. & Ruffin, M., Nov 1 2013, In : Journal of the American Board of Family Medicine. 26, 6, p. 720-727 8 p.

    Research output: Contribution to journalArticle

    2 Scopus citations