• 4938 Citations
  • 36 h-Index
19952020

Research output per year

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Research Output

2020

A Novel Antiparasitic Compound Kills Ring-Stage Plasmodium falciparum and Retains Activity against Artemisinin-Resistant Parasites

Clements, R. L., Streva, V., Dumoulin, P., Huang, W., Owens, E., Raj, D. K., Burleigh, B., Llinás, M., Winzeler, E. A., Zhang, Q. & Dvorin, J. D., Mar 15 2020, In : Journal of Infectious Diseases. 221, 6, p. 956-962 7 p.

Research output: Contribution to journalArticle

A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity

Akkaya, M., Bansal, A., Sheehan, P. W., Pena, M., Molina-Cruz, A., Orchard, L. M., Cimperman, C. K., Qi, C. F., Ross, P., Yazew, T., Sturdevant, D., Anzick, S. L., Thiruvengadam, G., Otto, T. D., Billker, O., Llinás, M., Miller, L. H. & Pierce, S. K., Feb 5 2020, In : Science Advances. 6, 6, eaaw6957.

Research output: Contribution to journalArticle

Open Access

Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery

Murithi, J. M., Owen, E. S., Istvan, E. S., Lee, M. C. S., Ottilie, S., Chibale, K., Goldberg, D. E., Winzeler, E. A., Llinás, M., Fidock, D. A. & Vanaerschot, M., Feb 20 2020, In : Cell Chemical Biology. 27, 2, p. 158-171.e3

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum

Schalkwijk, J., Allman, E. L., Jansen, P. A. M., De Vries, L. E., Verhoef, J. M. J., Jackowski, S., Botman, P. N. M., Beuckens-Schortinghuis, C. A., Koolen, K. M. J., Bolscher, J. M., Vos, M. W., Miller, K., Reeves, S. A., Pett, H., Trevitt, G., Wittlin, S., Scheurer, C., Sax, S., Fischli, C., Angulo-Barturen, I. & 11 others, Jiménez-Diaz, M. B., Josling, G., Kooij, T. W. A., Bonnert, R., Campo, B., Blaauw, R. H., Rutjes, F. P. J. T., Sauerwein, R. W., Llinás, M., Hermkens, P. H. H. & Dechering, K. J., Sep 18 2019, In : Science Translational Medicine. 11, 510, eaas9917.

Research output: Contribution to journalArticle

2 Scopus citations

Commitment Isn't for Everyone

Josling, G. A. & Llinás, M., Jun 2019, In : Trends in Parasitology. 35, 6, p. 381-383 3 p.

Research output: Contribution to journalShort survey

Cutting back malaria: CRISPR/Cas9 genome editing of Plasmodium

Lee, M. C. S., Lindner, S. E., Lopez-Rubio, J. J. & Llinás, M., Sep 24 2019, In : Briefings in functional genomics. 18, 5, p. 281-289 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation

Van Biljon, R., Van Wyk, R., Painter, H. J., Orchard, L., Reader, J., Niemand, J., Llinás, M. & Birkholtz, L. M., Dec 3 2019, In : BMC genomics. 20, 1, 920.

Research output: Contribution to journalArticle

1 Scopus citations

Identifying the Components of Acidosis in Patients with Severe Plasmodium falciparum Malaria Using Metabolomics

Leopold, S. J., Ghose, A., Allman, E. L., Kingston, H. W. F., Hossain, A., Dutta, A. K., Plewes, K., Chotivanich, K., Day, N. P. J., Tarning, J., Winterberg, M., White, N. J., Llinás, M. & Dondorp, A. M., Jun 1 2019, In : Journal of Infectious Diseases. 219, 11, p. 1766-1776 11 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Plasmodium niemann-pick type C1- related protein is a druggable target required for parasite membrane homeostasis

Istvan, E. S., Das, S., Bhatnagar, S., Beck, J. R., Owen, E., Llinas, M., Ganesan, S. M., Niles, J. C., Winzeler, E., Vaidya, A. B. & Goldberg, D. E., Mar 2019, In : eLife. 8, e40529.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

The g9a histone methyltransferase inhibitor BIX-01294 modulates gene expression during plasmodium falciparum gametocyte development and transmission

Ngwa, C. J., Kiesow, M. J., Orchard, L. M., Farrukh, A., Llinás, M. & Pradel, G., Oct 2 2019, In : International journal of molecular sciences. 20, 20, 5087.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum

Bennink, S., von Bohl, A., Ngwa, C. J., Henschel, L., Kuehn, A., Pilch, N., Weißbach, T., Rosinski, A. N., Scheuermayer, M., Repnik, U., Przyborski, J. M., Minns, A. M., Orchard, L. M., Griffiths, G., Lindner, S. E., Llinás, M. & Pradel, G., Aug 2018, In : PLoS pathogens. 14, 8, e1007249.

Research output: Contribution to journalArticle

3 Scopus citations

Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

Lee, A. H., Dhingra, S. K., Lewis, I. A., Singh, M. K., Siriwardana, A., Dalal, S., Rubiano, K., Klein, M. S., Baska, K. S., Krishna, S., Klemba, M., Roepe, P. D., Llinás, M., Garcia, C. R. S. & Fidock, D. A., Dec 1 2018, In : Scientific reports. 8, 1, 13578.

Research output: Contribution to journalArticle

5 Scopus citations

Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development

Painter, H. J., Chung, N. C., Sebastian, A., Albert, I., Storey, J. D. & Llinás, M., Dec 1 2018, In : Nature communications. 9, 1, 2656.

Research output: Contribution to journalArticle

17 Scopus citations

Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii

Shukla, A., Olszewski, K. L., Llinás, M., Rommereim, L. M., Fox, B. A., Bzik, D. J., Xia, D., Wastling, J., Beiting, D., Roos, D. S. & Shanmugam, D., Oct 2018, In : International Journal for Parasitology. 48, 12, p. 955-968 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites

van Biljon, R., Niemand, J., van Wyk, R., Clark, K., Verlinden, B., Abrie, C., von Grüning, H., Smidt, W., Smit, A., Reader, J., Painter, H., Llinás, M., Doerig, C. & Birkholtz, L. M., Dec 1 2018, In : Scientific reports. 8, 1, 16581.

Research output: Contribution to journalArticle

7 Scopus citations

Lipopeptisomes: Anticancer peptide-assembled particles for fusolytic oncotherapy

Aronson, M. R., Simonson, A. W., Orchard, L. M., Llinás, M. & Medina, S. H., Oct 15 2018, In : Acta Biomaterialia. 80, p. 269-277 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

Cowell, A. N., Istvan, E. S., Lukens, A. K., Gomez-Lorenzo, M. G., Vanaerschot, M., Sakata-Kato, T., Flannery, E. L., Magistrado, P., Owen, E., Abraham, M., La Monte, G., Painter, H. J., Williams, R. M., Franco, V., Linares, M., Arriaga, I., Bopp, S., Corey, V. C., Gnädig, N. F., Coburn-Flynn, O. & 24 others, Reimer, C., Gupta, P., Murithi, J. M., Moura, P. A., Fuchs, O., Sasaki, E., Kim, S. W., Teng, C. H., Wang, L. T., Akidil, A., Adjalley, S., Willis, P. A., Siegel, D., Tanaseichuk, O., Zhong, Y., Zhou, Y., Llinás, M., Ottilie, S., Gamo, F. J., Lee, M. C. S., Goldberg, D. E., Fidock, D. A., Wirth, D. F. & Winzeler, E. A., Jan 12 2018, In : Science. 359, 6372, p. 191-199 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

Antonova-Koch, Y., Meister, S., Abraham, M., Luth, M. R., Ottilie, S., Lukens, A. K., Sakata-Kato, T., Vanaerschot, M., Owen, E., Jado Rodriguez, J. C., Maher, S. P., Calla, J., Plouffe, D., Zhong, Y., Chen, K., Chaumeau, V., Conway, A. J., McNamara, C. W., Ibanez, M., Gagaring, K. & 18 others, Serrano, F. N., Eribez, K., Taggard, C. M. L., Cheung, A. L., Lincoln, C., Ambachew, B., Rouillier, M., Siegel, D., Nosten, F., Kyle, D. E., Gamo, F. J., Zhou, Y., Llinás, M., Fidock, D. A., Wirth, D. F., Burrows, J., Campo, B. & Winzeler, E. A., Dec 7 2018, In : Science. 362, 6419, eaat9446.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites

Josling, G. A., Williamson, K. C. & Llinás, M., Sep 8 2018, In : Annual Review of Microbiology. 72, p. 501-519 19 p.

Research output: Contribution to journalReview article

14 Scopus citations

Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site

Gisselberg, J. E., Herrera, Z., Orchard, L. M., Llinás, M. & Yeh, E., Feb 15 2018, In : Cell Chemical Biology. 25, 2, p. 185-193.e5

Research output: Contribution to journalArticle

8 Scopus citations
2017

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum

Painter, H. J., Carrasquilla, M. & Llinás, M., Jun 2017, In : Genome research. 27, 6, p. 1074-1086 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast

Shears, M. J., MacRae, J. I., Mollard, V., Goodman, C. D., Sturm, A., Orchard, L. M., Llinás, M., McConville, M. J., Botté, C. Y. & McFadden, G. I., Jan 1 2017, In : Cellular Microbiology. 19, 1, e12633.

Research output: Contribution to journalArticle

12 Scopus citations

Less Lipid, More Commitment

Llinás, M., Dec 14 2017, In : Cell. 171, 7, p. 1474-1476 3 p.

Research output: Contribution to journalShort survey

3 Scopus citations

Nutrient sensing modulates malaria parasite virulence

Mancio-Silva, L., Slavic, K., Grilo Ruivo, M. T., Grosso, A. R., Modrzynska, K. K., Vera, I. M., Sales-Dias, J., Gomes, A. R., Macpherson, C. R., Crozet, P., Adamo, M., Baena-Gonzalez, E., Tewari, R., Llinás, M., Billker, O. & Mota, M. M., Jul 13 2017, In : Nature. 547, 7662, p. 213-216 4 p.

Research output: Contribution to journalArticle

41 Scopus citations

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites

Coetzee, N., Sidoli, S., Van Biljon, R., Painter, H., Llinás, M., Garcia, B. A. & Birkholtz, L. M., Dec 1 2017, In : Scientific reports. 7, 1, 607.

Research output: Contribution to journalArticle

8 Scopus citations

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor

Santos, J. M., Josling, G., Ross, P., Joshi, P., Orchard, L., Campbell, T., Schieler, A., Cristea, I. M. & Llinás, M., Jun 14 2017, In : Cell Host and Microbe. 21, 6, p. 731-741.e10

Research output: Contribution to journalArticle

18 Scopus citations

Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite

Turnbull, L. B., Siwo, G. H., Button-Simons, K. A., Tan, A., Checkley, L. A., Painter, H. J., Llinás, M. & Ferdig, M. T., Nov 2017, In : PloS one. 12, 11, e0187595.

Research output: Contribution to journalArticle

1 Scopus citations

Transcriptional profiling defines histone acetylation as a regulator of gene expression during human-to-mosquito transmission of the malaria parasite Plasmodium falciparum

Ngwa, C. J., Kiesow, M. J., Papst, O., Orchard, L. M., Filarsky, M., Rosinski, A. N., Voss, T. S., Llinás, M. & Pradel, G., Jul 24 2017, In : Frontiers in Cellular and Infection Microbiology. 7, JUL, 320.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology

Gabryszewski, S. J., Dhingra, S. K., Combrinck, J. M., Lewis, I. A., Callaghan, P. S., Hassett, M. R., Siriwardana, A., Henrich, P. P., Lee, A. H., Gnädig, N. F., Musset, L., Llinás, M., Egan, T. J., Roepe, P. D. & Fidock, D. A., Nov 1 2016, In : PLoS pathogens. 12, 11, e1005976.

Research output: Contribution to journalArticle

16 Scopus citations

Metabolomic profiling of the Malaria Box reveals antimalarial target pathways

Allman, E. L., Painter, H. J., Samra, J., Carrasquilla, M. & Llinás, M., Nov 2016, In : Antimicrobial agents and chemotherapy. 60, 11, p. 6635-6643 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Van Voorhis, W. C., Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Alemán Resto, Y., Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S., Bickle, Q., Bounaadja, L. & 167 others, Bowling, T., Bosch, J., Boucher, L. E., Boyom, F. F., Brea, J., Brennan, M., Burton, A., Caffrey, C. R., Camarda, G., Carrasquilla, M., Carter, D., Belen Cassera, M., Chih-Chien Cheng, K., Chindaudomsate, W., Chubb, A., Colon, B. L., Colón-López, D. D., Corbett, Y., Crowther, G. J., Cowan, N., D’Alessandro, S., Le Dang, N., Delves, M., DeRisi, J. L., Du, A. Y., Duffy, S., Abd El-Salam El-Sayed, S., Ferdig, M. T., Fernández Robledo, J. A., Fidock, D. A., Florent, I., Fokou, P. V. T., Galstian, A., Gamo, F. J., Gokool, S., Gold, B., Golub, T., Goldgof, G. M., Guha, R., Guiguemde, W. A., Gural, N., Guy, R. K., Hansen, M. A. E., Hanson, K. K., Hemphill, A., Hooft van Huijsduijnen, R., Horii, T., Horrocks, P., Hughes, T. B., Huston, C., Igarashi, I., Ingram-Sieber, K., Itoe, M. A., Jadhav, A., Naranuntarat Jensen, A., Jensen, L. T., Jiang, R. H. Y., Kaiser, A., Keiser, J., Ketas, T., Kicka, S., Kim, S., Kirk, K., Kumar, V. P., Kyle, D. E., Lafuente, M. J., Landfear, S., Lee, N., Lee, S., Lehane, A. M., Li, F., Little, D., Liu, L., Llinás, M., Loza, M. I., Lubar, A., Lucantoni, L., Lucet, I., Maes, L., Mancama, D., Mansour, N. R., March, S., McGowan, S., Medina Vera, I., Meister, S., Mercer, L., Mestres, J., Mfopa, A. N., Misra, R. N., Moon, S., Moore, J. P., Morais Rodrigues da Costa, F., Müller, J., Muriana, A., Nakazawa Hewitt, S., Nare, B., Nathan, C., Narraidoo, N., Nawaratna, S., Ojo, K. K., Ortiz, D., Panic, G., Papadatos, G., Parapini, S., Patra, K., Pham, N., Prats, S., Plouffe, D. M., Poulsen, S. A., Pradhan, A., Quevedo, C., Quinn, R. J., Rice, C. A., Rizk, M. A., Ruecker, A., St. Onge, R., Salgado Ferreira, R., Samra, J., Robinett, N. G., Schlecht, U., Schmitt, M., Silva Villela, F., Silvestrini, F., Sinden, R., Smith, D. A., Soldati, T., Spitzmüller, A., Stamm, S. M., Sullivan, D. J., Sullivan, W., Suresh, S., Suzuki, B. M., Suzuki, Y., Swamidass, S. J., Taramelli, D., Tchokouaha, L. R. Y., Theron, A., Thomas, D., Tonissen, K. F., Townson, S., Tripathi, A. K., Trofimov, V., Udenze, K. O., Ullah, I., Vallieres, C., Vigil, E., Vinetz, J. M., Voong Vinh, P., Vu, H., Watanabe, N. A., Weatherby, K., White, P. M., Wilks, A. F., Winzeler, E. A., Wojcik, E., Wree, M., Wu, W., Yokoyama, N., Zollo, P. H. A., Abla, N., Blasco, B., Burrows, J., Laleu, B., Leroy, D., Spangenberg, T., Wells, T. & Willis, P. A., Jul 2016, In : PLoS pathogens. 12, 7, e1005763.

Research output: Contribution to journalArticle

107 Scopus citations

Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite

Cobbold, S. A., Santos, J. M., Ochoa, A., Perlman, D. H. & Llinas, M., Jan 27 2016, In : Scientific reports. 6, 19722.

Research output: Contribution to journalArticle

25 Scopus citations

Sequestration and metabolism of host cell arginine by the intraerythrocytic malaria parasite Plasmodium falciparum

Cobbold, S. A., Llinás, M. & Kirk, K., Jun 2016, In : Cellular Microbiology. 18, 6, p. 820-830 11 p., A820.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Beyond the E-Value: Stratified Statistics for Protein Domain Prediction

Ochoa, A., Storey, J. D., Llinás, M. & Singh, M., Nov 2015, In : PLoS computational biology. 11, 11, e1004509.

Research output: Contribution to journalArticle

7 Scopus citations

Genetic investigation of tricarboxylic acid metabolism during the plasmodium falciparum life cycle

Ke, H., Lewis, I. A., Morrisey, J. M., McLean, K. J., Ganesan, S. M., Painter, H. J., Mather, M. W., Jacobs-Lorena, M., Llinás, M. & Vaidya, A. B., Apr 7 2015, In : Cell Reports. 11, 1, p. 164-174 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1

Adjalley, S. H., Scanfeld, D., Kozlowski, E., Llinás, M. & Fidock, D. A., Dec 21 2015, In : BMC genomics. 16, 1, 1090.

Research output: Contribution to journalArticle

9 Scopus citations

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities

Pulcini, S., Staines, H. M., Lee, A. H., Shafik, S. H., Bouyer, G., Moore, C. M., Daley, D. A., Hoke, M. J., Altenhofen, L. M., Painter, H. J., Mu, J., Ferguson, D. J. P., Llinás, M., Martin, R. E., Fidock, D. A., Cooper, R. A. & Krishna, S., Sep 30 2015, In : Scientific reports. 5, 14552.

Research output: Contribution to journalArticle

23 Scopus citations

PfSR1 controls alternative splicing and steady-state RNA levels in Plasmodium falciparum through preferential recognition of specific RNA motifs

Eshar, S., Altenhofen, L., Rabner, A., Ross, P., Fastman, Y., Mandel-Gutfreund, Y., Karni, R., Llinás, M. & Dzikowski, R., Jun 1 2015, In : Molecular Microbiology. 96, 6, p. 1283-1297 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Sexual development in Plasmodium parasites: Knowing when it's time to commit

Josling, G. A. & Llinás, M., Aug 14 2015, In : Nature Reviews Microbiology. 13, 9, p. 573-587 15 p.

Research output: Contribution to journalReview article

72 Scopus citations
2014

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium

Sinha, A., Hughes, K. R., Modrzynska, K. K., Otto, T. D., Pfander, C., Dickens, N. J., Religa, A. A., Bushell, E., Graham, A. L., Cameron, R., Kafsack, B. F. C., Williams, A. E., Llinás, M., Berriman, M., Billker, O. & Waters, A. P., Jan 1 2014, In : Nature. 507, 7491, p. 253-257 5 p.

Research output: Contribution to journalArticle

170 Scopus citations

A Plasmodium falciparum Histone Deacetylase regulates antigenic variation and gametocyte conversion

Coleman, B. I., Skillman, K. M., Jiang, R. H. Y., Childs, L. M., Altenhofen, L. M., Ganter, M., Leung, Y., Goldowitz, I., Kafsack, B. F. C., Marti, M., Llinas, M., Buckee, C. O. & Duraisingh, M. T., Aug 13 2014, In : Cell Host and Microbe. 16, 2, p. 177-186 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

A transcriptional switch underlies commitment to sexual development in malaria parasites

Kafsack, B. F. C., Rovira-Graells, N., Clark, T. G., Bancells, C., Crowley, V. M., Campino, S. G., Williams, A. E., Drought, L. G., Kwiatkowski, D. P., Baker, D. A., Cortés, A. & Llinás, M., Jan 1 2014, In : Nature. 507, 7491, p. 248-252 5 p.

Research output: Contribution to journalArticle

176 Scopus citations

Cross-reactive immune responses as primary drivers of malaria chronicity

Klein, E. Y., Graham, A. L., Llinás, M. & Levin, S., Jan 1 2014, In : Infection and Immunity. 82, 1, p. 140-151 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

Lewis, I. A., Wacker, M., Olszewski, K. L., Cobbold, S. A., Baska, K. S., Tan, A., Ferdig, M. T. & Llinás, M., Jan 1 2014, In : PLoS genetics. 10, 1, e1004085.

Research output: Contribution to journalArticle

45 Scopus citations

Supergenomic network compression and the discovery of exp1 as a glutathione transferase inhibited by artesunate

Lisewski, A. M., Quiros, J. P., Ng, C. L., Adikesavan, A. K., Miura, K., Putluri, N., Eastman, R. T., Scanfeld, D., Regenbogen, S. J., Altenhofen, L., Llinás, M., Sreekumar, A., Long, C., Fidock, D. A. & Lichtarge, O., Aug 14 2014, In : Cell. 158, 4, p. 916-928 13 p.

Research output: Contribution to journalArticle

56 Scopus citations

Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum

O'Hara, J. K., Kerwin, L. J., Cobbold, S. A., Tai, J., Bedell, T. A., Reider, P. J. & Llinás, M., Apr 18 2014, In : PloS one. 9, 4, e94061.

Research output: Contribution to journalArticle

22 Scopus citations

The Cryptosporidium parvum ApiAP2 gene family: Insights into the evolution of apicomplexan AP2 regulatory systems

Oberstaller, J., Pumpalova, Y., Schieler, A., Llinás, M. & Kissinger, J. C., 2014, In : Nucleic acids research. 42, 13, p. 8271-8284 14 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

A new system for comparative functional genomics of Saccharomyces yeasts

Caudy, A. A., Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., Scott Breunig, J., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A. & 54 others, Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. H. H., Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G. & Dunham, M. J., Sep 17 2013, In : Genetics. 195, 1, p. 275-287 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst

Radke, J. B., Lucas, O., De Silva, E. K., Ma, Y., Sullivan, W. J., Weiss, L. M., Llinas, M. & White, M. W., Apr 23 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 17, p. 6871-6876 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites

Mira-Martínez, S., Rovira-Graells, N., Crowley, V. M., Altenhofen, L. M., Llinás, M. & Cortés, A., Nov 1 2013, In : Cellular Microbiology. 15, 11, p. 1913-1923 11 p.

Research output: Contribution to journalArticle

36 Scopus citations