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Mark Hedglin

    • 435 Citations
    • 10 h-Index
    20072019
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    • 9 Similar Profiles
    3-methyladenine-DNA glycosylase Medicine & Life Sciences
    Proliferating Cell Nuclear Antigen Medicine & Life Sciences
    DNA Chemical Compounds
    Clamping devices Chemical Compounds
    Single-Stranded DNA Medicine & Life Sciences
    Replication Protein A Medicine & Life Sciences
    DNA Damage Medicine & Life Sciences
    Holoenzymes Medicine & Life Sciences

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    Projects 2012 2015

    Polymerase Switching During Translesion DNA Synthesis within the Human System

    Hedglin, M.

    National Institutes of Health

    9/1/12 → 8/31/15

    Project: Research project

    DNA-Directed DNA Polymerase
    DNA
    DNA Replication
    Mutation
    Neoplasms

    Research Output 2007 2019

    • 435 Citations
    • 10 h-Index
    • 13 Article
    • 1 Review article
    1 Citation (Scopus)

    Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

    Hedglin, M., Aitha, M., Pedley, A. & Benkovic, S. J., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5157-5168 12 p.

    Research output: Contribution to journal › Article

    Replication Protein A
    Proliferating Cell Nuclear Antigen
    DNA
    Post Translational Protein Processing
    DNA Replication
    16 Citations (Scopus)

    Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle

    Hedglin, M. & Benkovic, S., Jun 28 2017, In : Chemical Reviews. 117, 12, p. 7857-7877 21 p.

    Research output: Contribution to journal › Review article

    DNA
    Damage tolerance
    Cells
    Cell death
    DNA-Directed DNA Polymerase
    4 Citations (Scopus)

    Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA

    Hedglin, M., Aitha, M. & Benkovic, S., Jul 11 2017, In : Biochemistry. 56, 27, p. 3415-3421 7 p.

    Research output: Contribution to journal › Article

    Single-Stranded DNA
    Proliferating Cell Nuclear Antigen
    Monitoring
    DNA
    Proteins
    9 Citations (Scopus)

    Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

    Hedglin, M. & Benkovic, S., Apr 4 2017, In : Biochemistry. 56, 13, p. 1824-1835 12 p.

    Research output: Contribution to journal › Article

    Replication Protein A
    Single-Stranded DNA
    Clamping devices
    Proliferating Cell Nuclear Antigen
    DNA
    22 Citations (Scopus)

    Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

    Hedglin, M., Pandey, B. & Benkovic, S. J., Oct 22 2016, In : eLife. 5, OCTOBER2016, e19788.

    Research output: Contribution to journal › Article

    DNA
    Proliferating Cell Nuclear Antigen
    DNA-Directed DNA Polymerase
    Ubiquitination
    Post Translational Protein Processing