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Fingerprint Dive into the research topics where Mark Hedglin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
3-methyladenine-DNA glycosylase Medicine & Life Sciences
Proliferating Cell Nuclear Antigen Medicine & Life Sciences
DNA Chemical Compounds
Clamping devices Chemical Compounds
Single-Stranded DNA Medicine & Life Sciences
Replication Protein A Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Holoenzymes Medicine & Life Sciences

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Projects 2012 2015

DNA-Directed DNA Polymerase
DNA
DNA Replication
Mutation
Neoplasms

Research Output 2007 2019

  • 424 Citations
  • 10 h-Index
  • 13 Article
  • 1 Review article

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

Hedglin, M., Aitha, M., Pedley, A. & Benkovic, S. J., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5157-5168 12 p.

Research output: Contribution to journalArticle

Replication Protein A
Proliferating Cell Nuclear Antigen
DNA
Post Translational Protein Processing
DNA Replication
16 Citations (Scopus)

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle

Hedglin, M. & Benkovic, S., Jun 28 2017, In : Chemical Reviews. 117, 12, p. 7857-7877 21 p.

Research output: Contribution to journalReview article

DNA
Damage tolerance
Cells
Cell death
DNA-Directed DNA Polymerase
4 Citations (Scopus)

Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA

Hedglin, M., Aitha, M. & Benkovic, S., Jul 11 2017, In : Biochemistry. 56, 27, p. 3415-3421 7 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
Proliferating Cell Nuclear Antigen
Monitoring
DNA
Proteins
9 Citations (Scopus)

Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

Hedglin, M. & Benkovic, S., Apr 4 2017, In : Biochemistry. 56, 13, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Replication Protein A
Single-Stranded DNA
Clamping devices
Proliferating Cell Nuclear Antigen
DNA
20 Citations (Scopus)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

Hedglin, M., Pandey, B. & Benkovic, S., Oct 22 2016, In : eLife. 5, OCTOBER2016, e19788.

Research output: Contribution to journalArticle

DNA
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
Ubiquitination
Post Translational Protein Processing