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Matthew Coates, MD, PhD

    • 938 Citations
    • 9 h-Index
    20042020

    Research output per year

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    Personal profile

    Research interests

    Dr. Matthew Coates is a physician-scientist with long-standing research interest relating to the interplay between inflammatory bowel disease (IBD) and neuroendocrine signaling systems. To this end, he has focused much of his effort evaluating intestinal serotonin, neurotrophic and other signaling systems in the context of IBD and other inflammatory disorders of the gut. He is also very interested in how these factors impact visceral sensation and other key functions of the gastrointestinal tract.

    His laboratory utilizes a variety of innovative molecular (e.g., next-generation genomics, immunohistochemistry, immunoassays) and functional (e.g., quantitative sensory and visceromotor testing) techniques to investigate these issues.

    Dr. Coates is also overseeing the development of a gastroenterology-based intestinal disease data registry and biorepository. As part of this effort, critical data and tissue samples (including endoscopically derived intestinal biopsies and blood) are collected in order to facilitate multi-modal, prospective studies related to the research interests described above as well as related topics.

    Education/Academic qualification

    Gastroenterology, Hepatology and Nutrition, Fellowship, University of Pittsburgh School of Medicine

    … → Aug 2013

    Internal Medicine, Residency, University of Vermont College of Medicine

    … → Jun 2010

    MD, University of Vermont College of Medicine

    … → May 2007

    PhD, University of Vermont College of Medicine

    … → May 2005

    AB, Princeton University

    … → Jun 1996

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    Projects

    The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease

    Coates, M.

    NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

    4/10/20 → 1/31/21

    Project: Research project

    • Research Output

    • 938 Citations
    • 9 h-Index
    • 16 Article
    • 3 Review article
    • 1 Comment/debate
    • 1 Letter

    Gastrointestinal hypoalgesia in inflammatory bowel disease

    Coates, M. D., Soriano, C., Dalessio, S., Stuart, A., Walter, V., Koltun, W., Bernasko, N., Tinsley, A., Clarke, K. & Williams, E. D., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 45-52 8 p.

    Research output: Contribution to journal › Article

    Open Access

    • A single nucleotide polymorphism in dopamine beta hydroxylase (rs6271(C>T)) is over-represented in inflammatory bowel disease patients and reduces circulating enzyme

    Gonzalez-Lopez, E., Kawasawa-Imamura, Y., Zhang, L., Huang, X., Koltun, W. A., Coates, M. D. & Vrana, K. E., Feb 2019, In : PloS one. 14, 2, e0210175.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Erratum: Increased risk of influenza and influenza-related complications among 140,480 patients with inflammatory bowel disease (Inflammatory Bowel Diseases (izy243) DOI: 10.1093/ibd/izy243)

    Tinsley, A., Navabi, S., Williams, E. D., Liu, G., Kong, L., Coates, M. D. & Clarke, K., Oct 1 2019, In : Inflammatory bowel diseases. 25, 10, p. E135

    Research output: Contribution to journal › Comment/debate

    • 1 Scopus citations

    Impact of the NaV1.8 variant, A1073V, on post-sigmoidectomy pain and electrophysiological function in rat sympathetic neurons

    Coates, M. D., Kim, J. S., Carkaci-Salli, N., Vrana, K. E., Koltun, W. A., Puhl, H. L., Adhikary, S. D., Janicki, P. K. & Ruiz-Velasco, V., Dec 2019, In : Journal of neurophysiology. 122, 6, p. 2591-2600 10 p.

    Research output: Contribution to journal › Article

    • Increased Risk of Influenza and Influenza-Related Complications among 140,480 Patients with Inflammatory Bowel Disease

    Tinsley, A., Navabi, S., Williams, E. D., Liu, G., Kong, L., Coates, M. D. & Clarke, K., Jan 10 2019, In : Inflammatory bowel diseases. 25, 2, p. 369-376 8 p.

    Research output: Contribution to journal › Article

    • 12 Scopus citations