Matthew Coates, MD, PhD

    • 891 Citations
    • 7 h-Index
    20042019
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    Personal profile

    Research interests

    Dr. Matthew Coates is a physician-scientist with long-standing research interest relating to the interplay between inflammatory bowel disease (IBD) and neuroendocrine signaling systems. To this end, he has focused much of his effort evaluating intestinal serotonin, neurotrophic and other signaling systems in the context of IBD and other inflammatory disorders of the gut. He is also very interested in how these factors impact visceral sensation and other key functions of the gastrointestinal tract.

    His laboratory utilizes a variety of innovative molecular (e.g., next-generation genomics, immunohistochemistry, immunoassays) and functional (e.g., quantitative sensory and visceromotor testing) techniques to investigate these issues.

    Dr. Coates is also overseeing the development of a gastroenterology-based intestinal disease data registry and biorepository. As part of this effort, critical data and tissue samples (including endoscopically derived intestinal biopsies and blood) are collected in order to facilitate multi-modal, prospective studies related to the research interests described above as well as related topics.

    Education/Academic qualification

    Gastroenterology, Hepatology and Nutrition, Fellowship, University of Pittsburgh School of Medicine

    … → Aug 2013

    Internal Medicine, Residency, University of Vermont College of Medicine

    … → Jun 2010

    MD, University of Vermont College of Medicine

    … → May 2007

    PhD, University of Vermont College of Medicine

    … → May 2005

    AB, Princeton University

    … → Jun 1996

    Fingerprint Dive into the research topics where Matthew Coates is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 10 Similar Profiles
    Inflammatory Bowel Diseases Medicine & Life Sciences
    Serotonin Medicine & Life Sciences
    Ulcerative Colitis Medicine & Life Sciences
    Abdominal Pain Medicine & Life Sciences
    Colonic Pouches Medicine & Life Sciences
    Pouchitis Medicine & Life Sciences
    Irritable Bowel Syndrome Medicine & Life Sciences
    Serotonin Plasma Membrane Transport Proteins Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 2005 2006

    Serotonin
    Reflex
    Enterochromaffin Cells
    Enterocytes
    Intestinal Mucosa

    Research Output 2004 2019

    • 891 Citations
    • 7 h-Index
    • 15 Article
    • 3 Review article
    • 1 Letter
    1 Citation (Scopus)
    Open Access
    dopamine beta-monooxygenase
    Dopamine beta-Hydroxylase
    inflammatory bowel disease
    Polymorphism
    Inflammatory Bowel Diseases

    Impact of the NaV1.8 variant, A1073V, on post-sigmoidectomy pain and electrophysiological function in rat sympathetic neurons

    Coates, M. D., Kim, J. S., Carkaci-Salli, N., Vrana, K. E., Koltun, W. A., Puhl, H. L., Adhikary, S. D., Janicki, P. K. & Ruiz-Velasco, V., Dec 1 2019, In : Journal of neurophysiology. 122, 6, p. 2591-2600 10 p.

    Research output: Contribution to journalArticle

    Abdominal Pain
    Postoperative Pain
    Analgesics
    Neurons
    Pain
    3 Citations (Scopus)
    Inflammatory Bowel Diseases
    Human Influenza
    Incidence
    Hospitalization
    Confidence Intervals

    Opioid Analgesics Do Not Improve Abdominal Pain or Quality of Life in Crohn’s Disease

    Coates, M. D., Seth, N., Clarke, K., Abdul-Baki, H., Mahoney, N., Walter, V., Regueiro, M. D., Ramos-Rivers, C., Koutroubakis, I. E., Bielefeldt, K. & Binion, D. G., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

    Research output: Contribution to journalArticle

    Crohn Disease
    Abdominal Pain
    Opioid Analgesics
    Quality of Life
    Pain
    Pouchitis
    Colonic Pouches
    Ulcerative Colitis
    Smoking