Mechelle Lewis, MS, PhD

Associate Professor, Department of Neurology
Associate Professor, Department of Pharmacology

https://orcid.org/0000-0002-1375-689X

2127 Citations
23 h-Index

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13 Similar Profiles

Parkinson Disease Medicine & Life Sciences

Manganese Chemical Compounds

Substantia Nigra Medicine & Life Sciences

Welding Medicine & Life Sciences

Fingers Medicine & Life Sciences

Dopamine Agonists Medicine & Life Sciences

Basal Ganglia Medicine & Life Sciences

Anisotropy Medicine & Life Sciences

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Research Output 1998 2019

2127 Citations
23 h-Index
80 Article
3 Review article
1 Book
1 Comment/debate

2 Citations (Scopus)

Brain cholesterol metabolism and Parkinson's disease

Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M., Chen, H., Hohl, R. & Mailman, R., Mar 1 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.

Research output: Contribution to journal › Article

Parkinson Disease

Cholesterol

Brain

Odds Ratio

Logistic Models

Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders

Lee, E. Y., Flynn, M. R., Du, G., Lewis, M., Kong, L., Yanosky, J., Mailman, R. & Huang, X., Apr 1 2019, In : Toxicological Sciences. 168, 2, p. 486-496 11 p.

Research output: Contribution to journal › Article

Manganese

Alzheimer Disease

Hippocampus

Brain

Diffusion tensor imaging

Individual preferences in motor coordination seen across the two hands: relations to movement stability and optimality

de Freitas, P. B., Freitas, S. M. S. F., Lewis, M., Huang, X. & Latash, M., Jan 31 2019, In : Experimental Brain Research. 237, 1

Research output: Contribution to journal › Article

Hand

Fingers

Sensory Feedback

Social Adjustment

Task Performance and Analysis

5 Citations (Scopus)

Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease

Du, G., Lewis, M., Sica, C., Kong, L. & Huang, X., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 96-104 9 p.

Research output: Contribution to journal › Article

Parkinson Disease

Magnetic Resonance Spectroscopy

Sensitivity and Specificity

Area Under Curve

Magnetic Resonance Imaging

3 Citations (Scopus)

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

Sarkar, S., Rokad, D., Malovic, E., Luo, J., Harischandra, D. S., Jin, H., Anantharam, V., Huang, X., Lewis, M., Kanthasamy, A. & Kanthasamy, A. G., Jan 8 2019, In : Science Signaling. 12, 563, aat9900.

Research output: Contribution to journal › Article

Inflammasomes

Manganese

Exosomes

Interleukin-1

Neurodegenerative diseases