Projects per year
Personal profile
Research interests
Dr. Michael Katzman's research for more than two decades focused on the structure and function of the retroviral integrase enzyme that catalyzes the permanent integration of a copy of the retroviral genome into the DNA of an infected cell using three systems including human immunodeficiency virus (HIV), avian sarcoma viruses and visna virus. Among other contributions, he participated in the first purification of an enzymatically active retroviral integrase from a bacterial expression system, developed an assay still used to study this enzyme, created chimeric integrases to identify the parts of integrase that interact with viral or human DNA and the parts of viral DNA that interact with integrase, used HIV integrases from infected patients to identify an amino acid in the middle of the protein that contacts human DNA during integration, made mutations at this position to yield novel integrases that were improved at acting on viral DNA but impaired at acting on cellular DNA and explored the potential of stimulating integrase's ability to nick DNA nonspecifically for a novel antiviral strategy of using integrase to damage viral DNA. With the evolution of his career, Dr. Katzman's focus shifted to the appropriate usage of antimicrobial drugs in the healthcare setting, and in 2011 he established, and continues to direct, a successful Antimicrobial Stewardship Program at Penn State Health Milton S. Hershey Medical Center.
Dr. Katzman is a Distinguished Educator at Penn State College of Medicine and Director of the Antimicrobial Stewardship Program at Penn State Health Milton S. Hershey Medical Center.
Education/Academic qualification
Biochemistry and Medicine, Postdoctoral Fellow, Case Western Reserve University
1986 → 1989
Infectious Diseases, Fellowship, University Hospitals of Cleveland
1984 → 1989
Internal Medicine, Residency, University Hospitals of Cleveland
1981 → 1984
MD, Columbia University College of Physicians and Surgeons
1977 → 1981
AB, Columbia University
1973 → 1977
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Network
Projects
- 3 Finished
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Novel Stimulators of HIV-1 Integrase for Use in Combination Microbicide Regimens
National Institute of Allergy and Infectious Diseases
9/30/07 → 8/31/10
Project: Research project
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SUBSTRATE INTERACTIONS OF A MULTIFUNCTIONAL INTEGRASE
National Institute of Allergy and Infectious Diseases
4/15/00 → 3/31/02
Project: Research project
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STUDIES ON HIV-1 INTERGRATION
National Institute of Allergy and Infectious Diseases
8/1/92 → 5/31/97
Project: Research project
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Customizing an electronic medical record to automate the workflow and tracking of an antimicrobial stewardship program
Katzman, M., Kim, J., Lesher, M. D., Hale, C. M., McSherry, G. D., Loser, M. F., Ward, M. A. & Glasser, F. D., Jun 3 2019, In: Open Forum Infectious Diseases. 6, 8, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Compliance with Clostridium difficile treatment guidelines: Effect on patient outcomes
Crowell, K. T., Julian, K. G., Katzman, M., Berg, A. S., Tinsley, A., Williams, E. D., Koltun, W. A. & Messaris, E., Aug 1 2017, In: Epidemiology and Infection. 145, 11, p. 2185-2192 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Severe Babesia microti Infection in an Immunocompetent Host in Pennsylvania
Genda, J., Negron, EA., Lotfipour, M., Balabhadra, S., Desai, D., Craft, D. & Katzman, M., Aug 22 2016, In: Journal of Investigative Medicine High Impact Case Reports. 4, 3Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Building an antimicrobial stewardship program: Cooperative roles for pharmacists, infectious diseases specialists, and clinical microbiologists
Kim, J., Craft, D. W. & Katzman, M., Aug 1 2015, In: Laboratory Medicine. 46, 3, p. e65-e71Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Antibiotic therapy for Clostridium difficile infection
Katzman, M., 2014, In: Seminars in Colon and Rectal Surgery. 25, 3, p. 143-149 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Prizes
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Dean's Award for Excellence in Teaching
Aprile, Bettina (Recipient), Bezinover, Dmitri (Recipient), Blackall, George (Recipient), Booth, Jennifer (Recipient), Buchkovich, Nicholas (Recipient), Budde, Arne (Recipient), Burns, Amy (Recipient), Cartee, Todd (Recipient), Chu, David C. (Recipient), Cilley, R. (Recipient), Crook, Tonya (Recipient), Dalke, Katharine (Recipient), Dambro, Anthony (Recipient), De Jesus, Sol (Recipient), Demetriou, Theodore (Recipient), DeWaters, Ami (Recipient), Duca, Nicholas (Recipient), Evey, Loren (Recipient), Frauenhoffer, Elizabeth (Recipient), Garner, Matthew (Recipient), Glass, Kristen (Recipient), Goyal, Neerav (Recipient), Grine, Kristen (Recipient), Habib, S. (Recipient), Irby, Rosalyn (Recipient), Jones, Edward (Recipient), June, Rayford (Recipient), Karamchandani, K. (Recipient), Karpa, K. (Recipient), Kasmire, Kathryn (Recipient), Katzman, Michael (Recipient), Kavanagh, Robert (Recipient), Kees-Folts, Deborah (Recipient), Kesterson, J. (Recipient), Sciacca Kirby, Joslyn (Recipient), Kresch, Mitchell (Recipient), Lankford, Edward (Recipient), McDonald, A. (Recipient), Miller, Ronald (Recipient), Moldovan, George-Lucian (Recipient), Myler, Conrad (Recipient), Nelson, Amanda (Recipient), Neutze, Janet (Recipient), Newell, Jordan (Recipient), Norbury, Christopher (Recipient), O'Hara, Christopher (Recipient), Palmer, Timothy (Recipient), Pantanelli, Seth (Recipient), Pichardo-Lowden, Ariana (Recipient), Po, Wilson (Recipient), Radico, Julie (Recipient), Radtka, John (Recipient), Razeghi, S. (Recipient), Rodgers, R. (Recipient), Romanoski, Natasha (Recipient), Samson, Thomas (Recipient), Shantz, Lisa (Recipient), Smith, Brandon (Recipient), Stephens, Mark (Recipient) & Wang, Ming (Recipient), 2019
Prize
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