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1981 …2019
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Research Output 1981 2019

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1981
114 Citations (Scopus)

Superoxide dependent lipid peroxidation

Tien, M., Svingen, B. A. & Aust, S. D., Jan 1 1981, In : Federation Proceedings. 40, 2, p. 179-182 4 p.

Research output: Contribution to journalArticle

Xanthine Oxidase
Lipid Peroxides
Liver Microsomes
Unsaturated Fatty Acids
NADP
1982
141 Citations (Scopus)

An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation

Tien, M., Svingen, B. A. & Aust, S. D., Jan 1 1982, In : Archives of Biochemistry and Biophysics. 216, 1, p. 142-151 10 p.

Research output: Contribution to journalArticle

Xanthine Oxidase
Hydroxyl Radical
Lipid Peroxidation
Iron
Lipids
62 Citations (Scopus)
Liver
Liver Microsomes
Lipid Peroxidation
Rabbits
Lipids
136 Citations (Scopus)

The involvement of hydroxyl radical derived from hydrogen peroxide in lignin degradation by the white rot fungus Phanerochaete chrysosporium.

Forney, L. J., Reddy, C. A., Tien, M. & Aust, S. D., Oct 10 1982, In : Journal of Biological Chemistry. 257, 19, p. 11455-11462 8 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Fungi
Hydroxyl Radical
Hydrogen Peroxide
86 Citations (Scopus)

The multiple effects of ethylenediaminetetraacetate in several model lipid peroxidation systems

Tien, M., Morehouse, L. A., Bucher, J. R. & Aust, S. D., Oct 15 1982, In : Archives of Biochemistry and Biophysics. 218, 2, p. 450-458 9 p.

Research output: Contribution to journalArticle

Edetic Acid
Lipid Peroxidation
Lipids
Liposomes
NADPH-Ferrihemoprotein Reductase
129 Citations (Scopus)

Thiol-dependent lipid peroxidation

Tien, M., Bucher, J. R. & Aust, S. D., Jul 16 1982, In : Biochemical and Biophysical Research Communications. 107, 1, p. 279-285 7 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Lipid Peroxidation
Lipids
Iron
Cytochromes c
1983
54 Citations (Scopus)

Effect of hydrogen peroxide on the initiation of microsomal lipid peroxidation

Morehouse, L. A., Tien, M., Bucher, J. R. & Aust, S. D., Jan 1 1983, In : Biochemical Pharmacology. 32, 1, p. 123-127 5 p.

Research output: Contribution to journalArticle

Hydrogen Peroxide
Lipid Peroxidation
Lipids
Catalase
Azides
885 Citations (Scopus)

Lignin-degrading enzyme from the hymenomycete Phanerochaete chrysasporium burds

Tien, M. & Kent Kirk, T., Jan 1 1983, In : Science. 221, 4611, p. 661-663 3 p.

Research output: Contribution to journalArticle

Phanerochaete
Basidiomycota
lignin
Phanerochaete chrysosporium
extracellular fluids
49 Citations (Scopus)

Redox cycling and lipid peroxidation: The central role of iron chelates

Bucher, J. R., Tien, M., Morehouse, L. A. & Aust, S. D., Jul 1 1983, In : Toxicological Sciences. 3, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

Iron Chelating Agents
Lipid Peroxidation
Oxidation-Reduction
Lipids
Iron
218 Citations (Scopus)

The requirement for ferric in the initiation of lipid peroxidation by chelated ferrous iron

Bucher, J. R., Tien, M. & Aust, S. D., Mar 29 1983, In : Biochemical and Biophysical Research Communications. 111, 3, p. 777-784 8 p.

Research output: Contribution to journalArticle

Lipid Peroxidation
Iron
Lipids
Catalase
Reactive Oxygen Species
1984
4 Citations (Scopus)

Lignin-degrading enzyme from Phanerochaete chrysosporium

Kirk, T. K. & Tien, M., Aug 1 1984, In : Applied Biochemistry and Biotechnology. 9, 4, p. 317-318 2 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Enzymes
Chromatography
Aldehydes
1985
50 Citations (Scopus)

Free hydroxyl radical is not involved in an important reaction of lignin degradation by Phanerochaete chrysosporium Burds.

Kirk, T. K., Mozuch, M. D. & Tien, M., Jan 1 1985, In : The Biochemical journal. 226, 2, p. 455-460 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Free radicals
Hydroxyl Radical
Free Radicals
126 Citations (Scopus)

Mechanism of oxidative C(α)-C(β) cleavage of a lignin model dimer by Phanerochaete chrysosporium ligninase. Stoichiometry and involvement of free radicals

Hammel, K. E., Tien, M., Kalyanaraman, B. & Kirk, T. K., Dec 1 1985, In : Journal of Biological Chemistry. 260, 14, p. 8348-8353 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Stoichiometry
Dimers
Free Radicals
694 Citations (Scopus)

Oxidation of persistent environmental pollutants by a white rot fungus

Bumpus, J. A., Tien, M., Wright, D. & Aust, S. D., Jan 1 1985, In : Science. 228, 4706, p. 1434-1436 3 p.

Research output: Contribution to journalArticle

Phanerochaete
Environmental Pollutants
DDT
Fungi
Trichloroethanes
60 Citations (Scopus)

Resonance Raman Spectra of Extracellular Ligninase: Evidence for a Heme Active Site Similar to Those of Peroxidases

Kuila, D., Tien, M., Ondrias, M. R. & Fee, J. A., Jul 1 1985, In : Biochemistry. 24, 14, p. 3394-3397 4 p.

Research output: Contribution to journalArticle

Peroxidases
Heme
Raman scattering
Catalytic Domain
Lignin
274 Citations (Scopus)

The ligninase of Phanerochaete chrysosporium generates cation radicals from methoxybenzenes

Kersten, P. J., Tien, M., Kalyanaraman, B. & Kirk, T. K., Jan 1 1985, In : Journal of Biological Chemistry. 260, 5, p. 2609-2612 4 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Cations
Oxidation
Paramagnetic resonance
1986
138 Citations (Scopus)

Ligninase of Phanerochaete chrysosporium. Mechanism of its degradation of the non-phenolic arylglycerol β-aryl ether substructure of lignin

Kirk, T. K., Tien, M., Kersten, P. J., Mozuch, M. D. & Kalyanaraman, B., Jan 1 1986, In : Biochemical Journal. 236, 1, p. 279-287 9 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Ether
Cations
Degradation
41 Citations (Scopus)

Lignin degrading activity of Phanerochaete chrysosporium Burds. comparison of cellulase-negative and other strains

Kirk, T. K., Tien, M., Johnsrud, S. C. & Eriksson, K. E., Jan 1 1986, In : Enzyme and Microbial Technology. 8, 2, p. 75-80 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Cellulase
Lignin
Proteins
Glucose oxidase
381 Citations (Scopus)

Production of multiple ligninases by Phanerochaete chrysosporium: effect of selected growth conditions and use of a mutant strain

Kirk, T. K., Croan, S., Tien, M., Murtagh, K. E. & Farrell, R. L., Jan 1 1986, In : Enzyme and Microbial Technology. 8, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Alcohols
Growth
Fermenters
Proteins
197 Citations (Scopus)
Phanerochaete
Oxidation
Kinetics
Enzymes
Catalysis
1987
164 Citations (Scopus)

Cloning and sequencing of a cDNA for a ligninase from Phanerochaete chrysosporium

Tien, M. & Tu, C. P. D., Jan 1 1987, In : Nature. 326, 6112, p. 520-523 4 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Organism Cloning
Complementary DNA
Peroxidase
191 Citations (Scopus)

Properties of ligninase from phanerochaete chrysosporium and their possible applications

Tien, M., Jan 1 1987, In : Critical Reviews in Microbiology. 15, 2, p. 141-168 28 p.

Research output: Contribution to journalArticle

Phanerochaete
Basidiomycota
Oxygenases
Lignin
Catalysis
9 Citations (Scopus)

Selection and improvement of lignin-degrading microorganisms: Potential strategy based on lignin model-amino acid adducts

Tien, M., Kersten, P. J. & Kirk, T. K., Jan 1 1987, In : Applied and Environmental Microbiology. 53, 2, p. 242-245 4 p.

Research output: Contribution to journalArticle

lignin
microorganisms
amino acids
1988
1155 Citations (Scopus)

Lignin peroxidase of Phanerochaete chrysosporium

Tien, M. & Kirk, T. K., Jan 1 1988, In : Methods in Enzymology. 161, C, p. 238-249 12 p.

Research output: Contribution to journalArticle

Phanerochaete
Fermenters
Rubber
Oxygen
lignin peroxidase
47 Citations (Scopus)

Structure and regulation of a lignin peroxidase gene from Phanerochaete chrysosporium

Holzbaur, E. L. F. & Tien, M., Sep 15 1988, In : Biochemical and Biophysical Research Communications. 155, 2, p. 626-633 8 p.

Research output: Contribution to journalArticle

Phanerochaete
Genes
Isoenzymes
Introns
TATA Box
66 Citations (Scopus)

Studies on compound I formation of the lignin peroxidase from Phanerochaete chrysosporium.

Andrawis, A., Johnson, K. A. & Tien, M., Jan 1 1988, In : The Journal of biological chemistry. 263, 3, p. 1195-1198 4 p.

Research output: Contribution to journalArticle

Phanerochaete
Lignin
Peroxides
pH effects
Peroxidases
1989
27 Citations (Scopus)

Characterization of two lignin peroxidase clones from Phanerochaete chrysosporium

Andrawis, A., Pease, E. A., Kuan, I. C., Holzbaur, E. & Tien, M., Jul 31 1989, In : Biochemical and Biophysical Research Communications. 162, 2, p. 673-680 8 p.

Research output: Contribution to journalArticle

Phanerochaete
Isoenzymes
Clone Cells
Complementary DNA
Peroxidase
97 Citations (Scopus)

Manganese-dependent peroxidase from Phanerochaete chrysosporium. Primary structure deduced from cDNA sequence.

Pease, E. A., Andrawis, A. & Tien, M., Jan 1 1989, In : The Journal of biological chemistry. 264, 23, p. 13531-13535 5 p.

Research output: Contribution to journalArticle

manganese peroxidase
Phanerochaete
Complementary DNA
Amino Acids
Amino Acid Sequence
37 Citations (Scopus)

On the reactions of lignin peroxidase Compound III (isozyme H8)

Cai, D. & Tien, M., Jul 14 1989, In : Biochemical and Biophysical Research Communications. 162, 1, p. 464-469 6 p.

Research output: Contribution to journalArticle

Isoenzymes
Hydrogen Peroxide
Enzymes
Ferrous Compounds
Gel Chromatography
102 Citations (Scopus)

Oxidation-Reduction Potentials and Ionization States of Extracellular Peroxidases from the Lignin-Degrading Fungus Phanerochaete chrysosporium

Millis, C. D., Cai, D., Stankovich, M. T. & Tien, M., Jan 1 1989, In : Biochemistry. 28, 21, p. 8484-8489 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Fungi
Isoenzymes
Oxidation-Reduction
Ionization
32 Citations (Scopus)

Phosphorylation of lignin peroxidases from Phanerochaete chrysosporium. Identification of mannose 6-phosphate

Kuan, I. & Tien, M., Dec 20 1989, In : Journal of Biological Chemistry. 264, 34, p. 20350-20355 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Phosphorylation
Isoenzymes
manganese peroxidase
Phosphates
160 Citations (Scopus)

Physical and enzymatic properties of lignin peroxidase isoenzymes from Phanerochaete chrysosporium

Farrell, R. L., Murtagh, K. E., Tien, M., Mozuch, M. D. & Kirk, T. K., Jan 1 1989, In : Enzyme and Microbial Technology. 11, 6, p. 322-328 7 p.

Research output: Contribution to journalArticle

Isoenzymes
Phanerochaete
Lignin
Hemeproteins
Alcohols
1990
17 Citations (Scopus)
Phanerochaete
Isoenzymes
Kinetics
Myoglobin
lignin peroxidase
36 Citations (Scopus)

Lignin peroxidase from fungi: Phanerochaete chrysosporium

Kent Kirk, T., Tien, M., Kersten, P. J., Kalyanaraman, B., Hammel, K. E. & Farrell, R. L., Jan 1 1990, In : Methods in enzymology. 188, C, p. 159-171 13 p.

Research output: Contribution to journalArticle

Phanerochaete
Fungi
Isoenzymes
Lignin
Chromatography
43 Citations (Scopus)
Phanerochaete
Phanerochaete chrysosporium
Lignin
lignin
Lysine
1991
46 Citations (Scopus)
manganese peroxidase
Phanerochaete
Baculoviridae
Isoenzymes
Enzymes
17 Citations (Scopus)

Lignin peroxidase of Phanerochaete chrysosporium: Evidence for an acidic ionization controlling activity

Cai, D. & Tien, M., 1991, In : Journal of Biological Chemistry. 266, 22, p. 14464-14469 6 p.

Research output: Contribution to journalArticle

Phanerochaete
Ionization
Chlorides
Peroxidases
Catalytic Domain
46 Citations (Scopus)

Overproduction of lignin-degrading enzymes by an isolate of Phanerochaete chrysosporium

Orth, A. B., Denny, M. & Tien, M., 1991, In : Applied and Environmental Microbiology. 57, 9, p. 2591-2596 6 p.

Research output: Contribution to journalArticle

manganese peroxidase
lignin peroxidase
Phanerochaete
Phanerochaete chrysosporium
Lignin
97 Citations (Scopus)

Proton NMR investigation into the basis for the relatively high redox potential of lignin peroxidase

Banci, L., Bertini, I., Turano, P., Tien, M. & Kirk, T. K., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 16, p. 6956-6960 5 p.

Research output: Contribution to journalArticle

Cytochrome-c Peroxidase
Oxidation-Reduction
Protons
Horseradish Peroxidase
Heme
1992
67 Citations (Scopus)

1H NMR Investigation of Manganese Peroxidase from Phanerochaete chrysosporium. A Comparison with Other Peroxidases

Banci, L., Bertini, I., Turano, P., Pease, E. A. & Tien, M., Feb 1 1992, In : Biochemistry. 31, 41, p. 10009-10017 9 p.

Research output: Contribution to journalArticle

manganese peroxidase
Phanerochaete
Peroxidases
Cyanides
Nuclear magnetic resonance
18 Citations (Scopus)

An investigation into the role of lipid peroxidation in the mode of action of aromatic hydrocarbon and dicarboximide fungicides

Orth, A. B., Sfarra, A., Pell, E. J. & Tien, M., Jan 1 1992, In : Pesticide Biochemistry and Physiology. 44, 2, p. 91-100 10 p.

Research output: Contribution to journalArticle

dicarboximide fungicides
Aromatic Hydrocarbons
aromatic hydrocarbons
microsomes
Ustilago zeae
60 Citations (Scopus)

Heterogeneity and regulation of manganese peroxidases from Phanerochaete chrysosporium

Pease, E. A. & Tien, M., Jan 1 1992, In : Journal of bacteriology. 174, 11, p. 3532-3540 9 p.

Research output: Contribution to journalArticle

manganese peroxidase
Phanerochaete
Isoenzymes
Nitrogen
Carbon
62 Citations (Scopus)

Kinetic studies on the formation and decomposition of compounds II and III. Reactions of lignin peroxidase with H 2 O 2

Cai, D. & Tien, M., Jan 1 1992, In : Journal of Biological Chemistry. 267, 16, p. 11149-11155 7 p.

Research output: Contribution to journalArticle

Decomposition
Kinetics
Superoxides
Enzymes
Fluorides
22 Citations (Scopus)

Production and characterization of recombinant lignin peroxidase isozyme H2 from Phanerochaete chrysosporium using recombinant baculovirus

Johnson, T. M., Pease, E. A., Li, J. K. K. & Tien, M., Aug 1 1992, In : Archives of Biochemistry and Biophysics. 296, 2, p. 660-666 7 p.

Research output: Contribution to journalArticle

Phanerochaete
Baculoviridae
Isoenzymes
Guaiacol
Enzymes
1993
11 Citations (Scopus)

Assessing the Involvement of Free Radicals in Fungicide Toxicity Using α-Tocopherol Analogs

Orth, A. B., Sfarra, A., Pell, E. J. & Tien, M., Oct 1 1993, In : Pesticide Biochemistry and Physiology. 47, 2, p. 134-141 8 p.

Research output: Contribution to journalArticle

Tocopherols
tocopherols
Free Radicals
fungicides
toxicity
61 Citations (Scopus)

Binding of Horseradish, Lignin, and Manganese Peroxidases to Their Respective Substrates

Banci, L., Bertini, I., Bini, T., Tien, M. & Turano, P., Jan 1 1993, In : Biochemistry. 32, 22, p. 5825-5831 7 p.

Research output: Contribution to journalArticle

manganese peroxidase
Horseradish Peroxidase
Manganese
Substrates
Cyanides
22 Citations (Scopus)
manganese peroxidase
formic acid
Phanerochaete
Hydrogen Peroxide
Superoxides
137 Citations (Scopus)

Kinetic analysis of manganese peroxidase: The reaction with manganese complexes

Kuan, I. C., Johnson, K. A. & Tien, M., Sep 25 1993, In : Journal of Biological Chemistry. 268, 27, p. 20064-20070 7 p.

Research output: Contribution to journalArticle

manganese peroxidase
Oxalates
Manganese
Lactic Acid
Chelating Agents
56 Citations (Scopus)

Lignin and veratryl alcohol are not inducers of the ligninolytic system of Phanerochaete chrysosporium

Cancel, A. M., Orth, A. B. & Tien, M., Jan 1 1993, In : Applied and environmental microbiology. 59, 9, p. 2909-2913 5 p.

Research output: Contribution to journalArticle

lignin peroxidase
Phanerochaete
Phanerochaete chrysosporium
Lignin
lignin
36 Citations (Scopus)

Lignin-degrading peroxidases of Phanerochaete chrysosporium

Cai, D. & Tien, M., Jan 1 1993, In : Journal of Biotechnology. 30, 1, p. 79-90 12 p.

Research output: Contribution to journalArticle

Phanerochaete
Peroxidases
Lignin
Cytochrome-c Peroxidase
manganese peroxidase