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Research Output 2013 2019

  • 213 Citations
  • 10 h-Index
  • 13 Article
  • 4 Conference article
  • 3 Review article
2019

CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits

Lucas, A. M., Palmiero, N. E., McGuigan, J., Passero, K., Zhou, J., Orie, D., Ritchie, M. D. & Hall, M. A., Dec 18 2019, In : Frontiers in Genetics. 10, 1240.

Research output: Contribution to journalArticle

Open Access
Quality Control
Body Mass Index
Gene-Environment Interaction
Phenotype
Boidae
2018
2 Citations (Scopus)

Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS

Manduchi, E., Chesi, A., Hall, M. A., Grant, S. F. A. & Moore, J. H., Jan 1 2018, In : Pacific Symposium on Biocomputing. 0, 212669, p. 548-558 11 p.

Research output: Contribution to journalConference article

Genome-Wide Association Study
Medical problems
Nucleotides
Genomics
Polymorphism
2017
2 Citations (Scopus)

Analysis of Gene-Gene Interactions

Cole, B. S., Hall, M. A., Urbanowicz, R. J., Gilbert-Diamond, D. & Moore, J. H., Oct 2017, In : Current protocols in human genetics. 95, 1, p. 1.14.1-1.14.10

Research output: Contribution to journalReview article

Genes
Disease Susceptibility
Meta-Analysis
Research
Machine Learning
1 Citation (Scopus)

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Holzinger, E. R., Verma, S. S., Moore, C. B., Hall, M., De, R., Gilbert-Diamond, D., Lanktree, M. B., Pankratz, N., Amuzu, A., Burt, A., Dale, C., Dudek, S., Furlong, C. E., Gaunt, T. R., Kim, D. S., Riess, H., Sivapalaratnam, S., Tragante, V., Van Iperen, E. P. A., Brautbar, A. & 32 others, Carrell, D. S., Crosslin, D. R., Jarvik, G. P., Kuivaniemi, H., Kullo, I. J., Larson, E. B., Rasmussen-Torvik, L. J., Tromp, G., Baumert, J., Cruickshanks, K. J., Farrall, M., Hingorani, A. D., Hovingh, G. K., Kleber, M. E., Klein, B. E., Klein, R., Koenig, W., Lange, L. A., MOrz, W., North, K. E., Charlotte Onland-Moret, N., Reiner, A. P., Talmud, P. J., Van Der Schouw, Y. T., Wilson, J. G., Kivimaki, M., Kumari, M., Moore, J. H., Drenos, F., Asselbergs, F. W., Keating, B. J. & Ritchie, M. D., Jul 24 2017, In : BioData Mining. 10, 1, 25.

Research output: Contribution to journalArticle

Single nucleotide Polymorphism
Nucleotides
Lipids
Polymorphism
Replication
4 Citations (Scopus)

Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts

De, R., Verma, S. S., Holzinger, E., Hall, M., Burt, A., Carrell, D. S., Crosslin, D. R., Jarvik, G. P., Kuivaniemi, H., Kullo, I. J., Lange, L. A., Lanktree, M. B., Larson, E. B., North, K. E., Reiner, A. P., Tragante, V., Tromp, G., Wilson, J. G., Asselbergs, F. W., Drenos, F. & 4 others, Moore, J. H., Ritchie, M. D., Keating, B. & Gilbert-Diamond, D., Feb 1 2017, In : Human genetics. 136, 2, p. 165-178 14 p.

Research output: Contribution to journalArticle

Triglycerides
LDL Cholesterol
HDL Cholesterol
Lipids
Multifactor Dimensionality Reduction
26 Citations (Scopus)

Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health

Manrai, A. K., Cui, Y., Bushel, P. R., Hall, M., Karakitsios, S., Mattingly, C. J., Ritchie, M., Schmitt, C., Sarigiannis, D. A., Thomas, D. C., Wishart, D., Balshaw, D. M. & Patel, C. J., Mar 20 2017, In : Annual Review of Public Health. 38, p. 279-294 16 p.

Research output: Contribution to journalReview article

Informatics
Public Health
Genomics
Research
Environmental Exposure
7 Citations (Scopus)

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

Hall, M. A., Wallace, J., Lucas, A., Kim, D., Basile, A. O., Verma, S. S., McCarty, C. A., Brilliant, M. H., Peissig, P. L., Kitchner, T. E., Verma, A., Pendergrass, S. A., Dudek, S. M., Moore, J. H. & Ritchie, M. D., Dec 1 2017, In : Nature communications. 8, 1, 1167.

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
Software
Genes
computer programs
9 Citations (Scopus)

The joint effect of air pollution exposure and copy number variation on risk for autism

Kim, D., Volk, H., Girirajan, S., Pendergrass, S., Hall, M. A., Verma, S. S., Schmidt, R. J., Hansen, R. L., Ghosh, D., Ludena-Rodriguez, Y., Kim, K., Ritchie, M. D., Hertz-Picciotto, I. & Selleck, S. B., Sep 2017, In : Autism Research. 10, 9, p. 1470-1480 11 p.

Research output: Contribution to journalArticle

Air Pollution
Autistic Disorder
Ozone
Air Pollutants
Environmental Exposure
2016
14 Citations (Scopus)

Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine

Hall, M. A., Moore, J. H. & Ritchie, M. D., Aug 1 2016, In : Trends in Genetics. 32, 8, p. 470-484 15 p.

Research output: Contribution to journalReview article

Precision Medicine
Genetic Loci
Genome-Wide Association Study
Genotype
Genome
15 Citations (Scopus)

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

eMERGE Network & NEIGHBOR Consortium, Sep 2016, In : PLoS genetics. 12, 9, e1006186.

Research output: Contribution to journalArticle

Genetic Epistasis
glaucoma
Electronic Health Records
epistasis
Genomics
5 Citations (Scopus)

Identification of genetic interaction networks via an evolutionary algorithm evolved Bayesian network

Li, R., Dudek, S. M., Kim, D., Hall, M. A., Bradford, Y., Peissig, P. L., Brilliant, M. H., Linneman, J. G., McCarty, C. A., Bao, L. & Ritchie, M. D., May 10 2016, In : BioData Mining. 9, 1, 18.

Research output: Contribution to journalArticle

Bayesian networks
Bayesian Networks
Evolutionary algorithms
Precision Medicine
Type 2 Diabetes Mellitus
2015
10 Citations (Scopus)

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

Hall, M. A., Verma, S. S., Wallace, J., Lucas, A., Berg, R. L., Connolly, J., Crawford, D. C., Crosslin, D. R., de Andrade, M., Doheny, K. F., Haines, J. L., Harley, J. B., Jarvik, G. P., Kitchner, T., Kuivaniemi, H., Larson, E. B., Carrell, D. S., Tromp, G., Vrabec, T. R., Pendergrass, S. A. & 2 others, Mccarty, C. A. & Ritchie, M. D., Jul 1 2015, In : Genetic Epidemiology. 39, 5, p. 376-384 9 p.

Research output: Contribution to journalArticle

Electronic Health Records
Genomics
Cataract
Single Nucleotide Polymorphism
Genes
10 Citations (Scopus)

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

De, R., Verma, S. S., Drenos, F., Holzinger, E. R., Holmes, M. V., Hall, M. A., Crosslin, D. R., Carrell, D. S., Hakonarson, H., Jarvik, G., Larson, E., Pacheco, J. A., Rasmussen-Torvik, L. J., Moore, C. B., Asselbergs, F. W., Moore, J. H., Ritchie, M. D., Keating, B. J. & Gilbert-Diamond, D., Dec 14 2015, In : BioData Mining. 8, 1, 74.

Research output: Contribution to journalArticle

Multifactor Dimensionality Reduction
Single nucleotide Polymorphism
Dimensionality Reduction
Nucleotides
Polymorphism
2 Citations (Scopus)

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*

Pendergrass, S. A., Verma, S. S., Hall, M. A., Holzinger, E. R., Moore, C. B., Wallace, J. R., Dudek, S. M., Huggins, W., Kitchner, T., Waudby, C., Berg, R., Mccarty, C. A. & Ritchie, M. D., Jan 1 2015, In : Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. p. 495-505 11 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Cataract
Single Nucleotide Polymorphism
Electronic Health Records
Genes
11 Citations (Scopus)

Phenome-Wide Association Studies: Embracing Complexity for Discovery

Pendergrass, S. A., Verma, A., Okula, A., Hall, M. A., Crawford, D. C. & Ritchie, M. D., Jul 25 2015, In : Human heredity. 79, 3-4, p. 111-123 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Pleiotropy
Pharmacology
Biological Phenomena
Systems Analysis

Session introduction: Characterizing the importance of environmental exposures, interactions between the environment and genetic architecture, and genetic interactions: New methods for understanding the etiology of complex traits and disease

Hall, M. A., Verma, S. S., Wall, D. P., Moore, J. H., Keating, B., Campbell, D. B., Gibson, G., Asselbergs, F. W. & Pendergrass, S., Jan 1 2015, In : Pacific Symposium on Biocomputing. p. 156-160 5 p.

Research output: Contribution to journalConference article

2014
35 Citations (Scopus)

Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study

Hall, M. A., Verma, A., Brown-Gentry, K. D., Goodloe, R., Boston, J., Wilson, S., McClellan, B., Sutcliffe, C., Dilks, H. H., Gillani, N. B., Jin, H., Mayo, P., Allen, M., Schnetz-Boutaud, N., Crawford, D. C., Ritchie, M. D. & Pendergrass, S. A., Dec 1 2014, In : PLoS genetics. 10, 12

Research output: Contribution to journalArticle

pleiotropy
Mexican Americans
epidemiological studies
Single Nucleotide Polymorphism
phenotype
17 Citations (Scopus)

Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci

Ritchie, M. D., Verma, S. S., Hall, M. A., Goodloe, R. J., Berg, R. L., Carrell, D. S., Carlson, C. S., Chen, L., Crosslin, D. R., Denny, J. C., Jarvik, G., Li, R., Linneman, J. G., Pathak, J., Peissig, P., Rasmussen, L. V., Ramirez, A. H., Wang, X., Wilke, R. A., Wolf, W. A. & 3 others, Torstenson, E. S., Turner, S. D. & McCarty, C. A., Sep 19 2014, In : Molecular vision. 20, p. 1281-1295 15 p.

Research output: Contribution to journalArticle

Electronic Health Records
Genomics
Cataract
Single Nucleotide Polymorphism
Genome-Wide Association Study
23 Citations (Scopus)

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

Hall, M. A., Dudek, S. M., Goodloe, R., Crawford, D. C., Pendergrass, S. A., Peissig, P., Brilliant, M., McCarty, C. A. & Ritchie, M. D., Jan 1 2014, In : Pacific Symposium on Biocomputing. p. 200-211 12 p.

Research output: Contribution to journalConference article

Precision Medicine
Nutrition
Medical problems
Type 2 Diabetes Mellitus
Nutrition Surveys
2013
17 Citations (Scopus)

Next-generation analysis of cataracts: Determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the PhenX Toolkit

Pendergrass, S. A., Verma, S. S., Hall, M. A., Holzinger, E. R., Moore, C. B., Wallace, J. R., Dudek, S. M., Huggins, W., Kitchner, T., Waudby, C., Berg, R., McCarty, C. A. & Ritchie, M. D., Jan 1 2013, In : Pacific Symposium on Biocomputing. p. 147-158 12 p.

Research output: Contribution to journalConference article

Gene-Environment Interaction
Cataract
Single Nucleotide Polymorphism
Electronic Health Records
Genes