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Research Output 2004 2020

  • 606 Citations
  • 13 h-Index
  • 25 Article
  • 4 Review article
  • 1 Chapter
  • 1 Short survey
2020

Oligonucleotide Enrichment of HSV-1 Genomic DNA from Clinical Specimens for Use in High-Throughput Sequencing

Shipley, M. M., Rathbun, M. M. & Szpara, M. L., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 199-217 19 p. (Methods in Molecular Biology; vol. 2060).

Research output: Chapter in Book/Report/Conference proceedingChapter

Viral DNA
Human Herpesvirus 1
Oligonucleotides
High-Throughput Nucleotide Sequencing
Human Herpesvirus 2
2019
2 Citations (Scopus)

Comparison of herpes simplex virus 1 strains circulating in Finland demonstrates the uncoupling of whole-genome relatedness and phenotypic outcomes of viral infection

Bowen, C. D., Paavilainen, H., Renner, D. W., Palomäki, J., Lehtinen, J., Vuorinen, T., Norberg, P., Hukkanen, V. & Szpara, M. L., Jan 1 2019, In : Journal of virology. 93, 8, Y.

Research output: Contribution to journalArticle

Open Access
Human herpesvirus 1
Human Herpesvirus 1
Virus Diseases
Finland
Genome
5 Citations (Scopus)

Genotypic and phenotypic diversity of herpes simplex virus 2 within the infected neonatal population

Akhtar, L. N., Bowen, C. D., Renner, D. W., Pandey, U., Della Fera, A. N., Kimberlin, D. W., Prichard, M. N., Whitley, R. J., Weitzman, M. D. & Szpara, M. L., Jan 1 2019, In : mSphere. 4, 1, e00590-18.

Research output: Contribution to journalArticle

Open Access
Human Herpesvirus 2
Central Nervous System Diseases
Simplexvirus
Glycoproteins
Viral Genome
1 Citation (Scopus)

Herpes Simplex Virus Disease Management and Diagnostics in the Era of High-Throughput Sequencing

Pandey, U. & Szpara, M. L., Mar 1 2019, In : Clinical Microbiology Newsletter. 41, 5, p. 41-48 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Simplexvirus
Disease Management
Human Herpesvirus 2
Human Herpesvirus 1
Open Access
Human Herpesvirus 1
Virus Diseases
Alzheimer Disease
Viruses
Infection
Virus Diseases
Simplexvirus
Infection
Central Nervous System Infections
Aptitude
2018
2 Citations (Scopus)

Expression of the purine biosynthetic enzyme phosphoribosyl formylglycinamidine synthase in neurons

Mangold, C. A., Yao, P. J., Du, M., Freeman, W. M., Benkovic, S. J. & Szpara, M. L., Mar 2018, In : Journal of neurochemistry. 144, 6, p. 723-735 13 p.

Research output: Contribution to journalArticle

Neurons
Purines
Virus Diseases
Enzymes
Brain
8 Citations (Scopus)

Genome-Wide Surveillance of Genital Herpes Simplex Virus Type 1 From Multiple Anatomic Sites Over Time

Shipley, M. M., Renner, D. W., Ott, M., Bloom, D. C., Koelle, D. M., Johnston, C. & Szpara, M. L., Jul 13 2018, In : Journal of Infectious Diseases. 218, 4, p. 595-605 11 p.

Research output: Contribution to journalArticle

Herpes Genitalis
Human Herpesvirus 1
Viral Genome
Genome
Virus Shedding
11 Citations (Scopus)

Impacts of genome-wide analyses on our understanding of human herpesvirus diversity and evolution

Renner, D. W. & Szpara, M. L., Jan 1 2018, In : Journal of virology. 92, 1, e00908-17.

Research output: Contribution to journalShort survey

Herpesviridae
Genome
genome
DNA Viruses
dsDNA viruses
2017
5 Citations (Scopus)

A model of genital herpes simplex virus Type 1 infection in Rhesus Macaques

Aravantinou, M., Frank, I., Arrode-Bruses, G., Szpara, M., Grasperge, B., Blanchard, J., Gettie, A., Derby, N. & Martinelli, E., Aug 2017, In : Journal of medical primatology. 46, 4, p. 121-128 8 p.

Research output: Contribution to journalArticle

Human herpesvirus 1
Herpes Genitalis
Human Herpesvirus 1
Macaca mulatta
genitalia
11 Citations (Scopus)

A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America

Trimpert, J., Groenke, N., Jenckel, M., He, S., Kunec, D., Szpara, M. L., Spatz, S. J., Osterrieder, N. & McMahon, D. P., Dec 2017, In : Evolutionary Applications. 10, 10, p. 1091-1101 11 p.

Research output: Contribution to journalArticle

Marek Disease
Mardivirus
Eurasia
North America
virulence
8 Citations (Scopus)

Differentiated human SHSY5Y cells provide a reductionist model of herpes simplex virus 1 neurotropism

Shipley, M. M., Mangold, C. A., Kuny, C. V. & Szpara, M. L., Dec 1 2017, In : Journal of virology. 91, 23, e00958-17.

Research output: Contribution to journalArticle

Human herpesvirus 1
Human Herpesvirus 1
neurons
viruses
cells
1 Citation (Scopus)

Experimental oral herpes simplex Virus-1 (HSV-1) co-infection in Simian Immunodeficiency Virus (SIV)-infected rhesus macaques

Aravantinou, M., Mizenina, O., Calenda, G., Kenney, J., Frank, I., Lifson, J. D., Szpara, M., Jing, L., Koelle, D. M., Teleshova, N., Grasperge, B., Blanchard, J., Gettie, A., Martinelli, E. & Derby, N., Dec 5 2017, In : Frontiers in Microbiology. 8, DEC, 2342.

Research output: Contribution to journalArticle

Herpetic Stomatitis
Simian Immunodeficiency Virus
Human Herpesvirus 1
Macaca mulatta
Coinfection
10 Citations (Scopus)

Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes

Pandey, U., Renner, D. W., Thompson, R. L., Szpara, M. L. & Sawtell, N. M., Dec 1 2017, In : Scientific reports. 7, 1, 13666.

Research output: Contribution to journalArticle

Viral Genome
Simplexvirus
Nuclear Family
Fathers
Viruses
2016
47 Citations (Scopus)

Differentiation of the SH-SY5Y human neuroblastoma cell line

Shipley, M. M., Mangold, C. A. & Szpara, M. L., Feb 17 2016, In : Journal of Visualized Experiments. 2016, 108, e53193.

Research output: Contribution to journalArticle

Neuroblastoma
Cells
Cell Line
Rats
Cell culture
8 Citations (Scopus)

DNA from dust: Comparative genomics of large DNA viruses in field surveillance samples

Pandey, U., Bell, A. S., Renner, D. W., Kennedy, D. A., Shreve, J. T., Cairns, C. L., Jones, M. J., Dunn, P. A., Read, A. F. & Szpara, M. L., Sep 1 2016, In : mSphere. 1, 5, e00132-16.

Research output: Contribution to journalArticle

DNA Viruses
Genomics
Dust
Genome
DNA
13 Citations (Scopus)

Viral forensic genomics reveals the relatedness of classic herpes simplex virus strains KOS, KOS63, and KOS79

Bowen, C. D., Renner, D. W., Shreve, J. T., Tafuri, Y., Payne, K. M., Dix, R. D., Kinchington, P. R., Gatherer, D. & Szpara, M. L., May 1 2016, In : Virology. 492, p. 179-186 8 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Simplexvirus
Genomics
Restriction Fragment Length Polymorphisms
Polymerase Chain Reaction
2015
19 Citations (Scopus)

Rapid genome assembly and comparison decode intrastrain variation in human alphaherpesviruses

Parsons, L. R., Tafuri, Y. R., Shreve, J. T., Bowen, C. D., Shipley, M. M., Enquist, L. W. & Szpara, M. L., Mar 31 2015, In : mBio. 6, 2, e02213-14.

Research output: Contribution to journalArticle

Viral Genome
Human Herpesvirus 1
Virus Assembly
Genome
Simplexvirus
15 Citations (Scopus)

VirAmp: A galaxy-based viral genome assembly pipeline

Wan, Y., Renner, D. W., Albert, I. & Szpara, M. L., Jan 1 2015, In : GigaScience. 4, 1, 19.

Research output: Contribution to journalArticle

Galaxies
Virus Assembly
Viral Genome
Computational Biology
Software
2014
91 Citations (Scopus)

Evolution and diversity in human herpes simplex virus genomes

Szpara, M. L., Gatherer, D., Ochoa, A., Greenbaum, B., Dolan, A., Bowden, R. J., Enquist, L. W., Legendre, M. & Davison, A. J., Jan 1 2014, In : Journal of virology. 88, 2, p. 1209-1227 19 p.

Research output: Contribution to journalArticle

Human herpesvirus 1
herpes simplex
Human Herpesvirus 1
Simplexvirus
Genome
4 Citations (Scopus)

Genome sequence of the anterograde-spread-defective herpes simplex virus 1 strain MacIntyre

Szpara, M. L., Tafuri, Y. R., Parsons, L., Shreve, J. T., Engel, E. A. & Enquist, L. W., Jan 1 2014, In : Genome Announcements. 2, 6, e01161-14.

Research output: Contribution to journalArticle

Defective Viruses
High-Throughput Nucleotide Sequencing
Human Herpesvirus 1
Encephalitis
Genome
2 Citations (Scopus)

Isolation of herpes simplex virus nucleocapsid DNA

Szpara, M., Jan 1 2014, In : Methods in Molecular Biology. 1144, p. 31-41 11 p.

Research output: Contribution to journalArticle

Nucleocapsid
Capsid
Viral DNA
Simplexvirus
Viral Genome
2011
88 Citations (Scopus)

A wide extent of inter-strain diversity in virulent and vaccine strains of Alphaherpesviruses

Szpara, M. L., Tafuri, Y. R., Parsons, L., Shamim, S. R., Verstrepen, K. J., Legendre, M. & Enquist, L. W., Oct 1 2011, In : PLoS pathogens. 7, 10, e1002282.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Human Herpesvirus 3
Vaccines
Herpesviridae
Genome
25 Citations (Scopus)

Herpes simplex virus 1 pUL34 plays a critical role in cell-to-cell spread of virus in addition to its role in virus replication

Haugo, A. C., Szpara, M. L., Parsons, L., Enquist, L. W. & Roller, R. J., Jul 1 2011, In : Journal of virology. 85, 14, p. 7203-7215 13 p.

Research output: Contribution to journalArticle

Human herpesvirus 1
Human Herpesvirus 1
Virus Replication
virus replication
Viruses
17 Citations (Scopus)

Preparation of viral DNA from nucleocapsids

Szpara, M. L., Tafuri, Y. R. & Enquist, L. W., Aug 1 2011, In : Journal of Visualized Experiments. 54, e3151.

Research output: Contribution to journalArticle

Nucleocapsid
Viral DNA
DNA
Viruses
Centrifugation
2010
31 Citations (Scopus)

A common neuronal response to alphaherpesvirus infection

Szpara, M. L., Kobiler, O. & Enquist, L. W., Sep 1 2010, In : Journal of Neuroimmune Pharmacology. 5, 3, p. 418-427 10 p.

Research output: Contribution to journalReview article

Infection
Herpesviridae
Genes
Suid Herpesvirus 1
Neurons
100 Citations (Scopus)

Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations

Szpara, M. L., Parsons, L. & Enquist, L. W., May 1 2010, In : Journal of virology. 84, 10, p. 5303-5313 11 p.

Research output: Contribution to journalArticle

Human herpesvirus 1
Human Herpesvirus 1
Genome
mutation
High-Throughput Nucleotide Sequencing
2009
21 Citations (Scopus)

Compartmented neuron cultures for unit 26.4 directional infection by alpha herpesviruses

Curanović, D., Ch'ng, T. H., Szpara, M. & Enquist, L., Jun 24 2009, In : Current Protocols in Cell Biology. SUPPL. 43, p. 26.4.1-26.4.23

Research output: Contribution to journalReview article

Herpesviridae Infections
Axons
Neurons
Herpesviridae
Polytetrafluoroethylene
28 Citations (Scopus)

Fluorescence-based monitoring of in vivo neural activity using a circuit-tracing pseudorabies virus

Granstedt, A. E., Szpara, M. L., Kuhn, B., Wang, S. S. H. & Enquist, L. W., Sep 9 2009, In : PloS one. 4, 9, e6923.

Research output: Contribution to journalArticle

Parasympathetic Ganglia
Suid Herpesvirus 1
Suid herpesvirus 1
action potentials
Viruses
2007
28 Citations (Scopus)

Analysis of gene expression during neurite outgrowth and regeneration

Szpara, M. L., Vranizan, K., Tai, Y., Goodman, C. S., Speed, T. P. & Ngai, J., Nov 23 2007, In : BMC Neuroscience. 8, 100.

Research output: Contribution to journalArticle

Regeneration
Superior Cervical Ganglion
Cues
Gene Expression
Spinal Ganglia
2004
2 Citations (Scopus)

Regulation of pontine neurite morphology by target-derived signals

Hansen, S. K., Szpara, M. L. & Serafini, T. A., May 19 2004, In : Molecular Brain Research. 124, 2, p. 165-177 13 p.

Research output: Contribution to journalArticle

Neurites
Molecular Weight
Neurons
Cerebellar Cortex
Nerve Growth Factors