• 5502 Citations
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1994 …2020

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Article
2020

PERSEVERE Biomarkers Predict Severe Acute Kidney Injury and Renal Recovery in Pediatric Septic Shock

Stanski, N. L., Stenson, E. K., Cvijanovich, N. Z., Weiss, S. L., Fitzgerald, J. C., Bigham, M. T., Jain, P. N., Schwarz, A., Lutfi, R., Nowak, J., Allen, G. L., Thomas, N. J., Grunwell, J. R., Baines, T., Quasney, M., Haileselassie, B. & Wong, H. R., Apr 1 2020, In : American journal of respiratory and critical care medicine. 201, 7, p. 848-855 8 p.

Research output: Contribution to journalArticle

2019

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Li, H., Torab, P., Mach, K. E., Surrette, C., England, M. R., Craft, D. W., Thomas, N. J., Liao, J. C., Puleo, C. & Wong, P. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10270-10279 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association between Tidal Volumes Adjusted for Ideal Body Weight and Outcomes in Pediatric Acute Respiratory Distress Syndrome∗

Imber, D. A., Thomas, N. J. & Yehya, N., Mar 1 2019, In : Pediatric Critical Care Medicine. 20, 3, p. E145-E153

Research output: Contribution to journalArticle

3 Scopus citations

Effects of ABO matching of platelet transfusions in critically III children

on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network, Pediatric Critical Care Blood Research Network (BloodNet) & The PT Investigators, Feb 1 2019, In : Pediatric Critical Care Medicine. 20, 2, p. E61-E69

Research output: Contribution to journalArticle

4 Scopus citations

Evidence of endotypes in pediatric acute hypoxemic respiratory failure caused by sepsis

Yehya, N., Thomas, N. J. & Wong, H. R., Feb 1 2019, In : Pediatric Critical Care Medicine. 20, 2, p. 110-112 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

International Study of the Epidemiology of Platelet Transfusions in Critically Ill Children with an Underlying Oncologic Diagnosis

on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Pediatric Critical Care Blood Research Network (BloodNet), and the Point Prevalence Study of Platelet Transfusions in Critically Ill Children (P3T) Investigators, Jul 1 2019, In : Pediatric Critical Care Medicine. 20, 7, p. e342-e351

Research output: Contribution to journalArticle

1 Scopus citations

Nanotube assisted microwave electroporation for single cell pathogen identification and antimicrobial susceptibility testing

Gao, J., Li, H., Torab, P., Mach, K. E., Craft, D. W., Thomas, N. J., Puleo, C. M., Liao, J. C., Wang, T. H. & Wong, P. K., Apr 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 17, p. 246-253 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators & Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Feb 2019, In : The Lancet Respiratory Medicine. 7, 2, p. 115-128 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model

Wong, H. R., Caldwell, J. T., Cvijanovich, N. Z., Weiss, S. L., Fitzgerald, J. C., Bigham, M. T., Jain, P. N., Schwarz, A., Lutfi, R., Nowak, J., Allen, G. L., Thomas, N. J., Grunwell, J. R., Baines, T., Quasney, M., Haileselassie, B. & Lindsell, C. J., Nov 13 2019, In : Science Translational Medicine. 11, 518, eaax9000.

Research output: Contribution to journalArticle

1 Scopus citations

Rapid Single-Cell Microbiological Analysis: Toward Precision Management of Infections and Dysbiosis

Li, H., Morowitz, M., Thomas, N. & Wong, P. K., Dec 1 2019, In : SLAS Technology. 24, 6, p. 603-605 3 p.

Research output: Contribution to journalArticle

Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis

SPROUT Investigators & Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Oct 2019, In : Journal of Surgical Research. 242, p. 100-110 11 p.

Research output: Contribution to journalArticle

Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data

Nalian, A., Umstead, T. M., Yang, C. H., Silveyra, P., Thomas, N. J., Floros, J., McCormack, F. X. & Chroneos, Z. C., Nov 7 2019, In : Frontiers in immunology. 10, 2613.

Research output: Contribution to journalArticle

Open Access

The association of early post-resuscitation hypotension with discharge survival following targeted temperature management for pediatric in-hospital cardiac arrest

for the Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators, Aug 2019, In : Resuscitation. 141, p. 24-34 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tracking resident pre-rounding electronic health record usage

Krawiec, C., Marker, C., Stetter, C., Kong, L. & Thomas, N. J., Apr 15 2019, In : International Journal of Health Care Quality Assurance. 32, 3, p. 611-620 10 p.

Research output: Contribution to journalArticle

Use of magnetic resonance imaging in severe pediatric traumatic brain injury: Assessment of current practice

Ferrazzano, P. A., Rosario, B. L., Wisniewski, S. R., Shaf, N. I., Siefkes, H. M., Miles, D. K., Alexander, A. L., Bell, M. J., Sarnaik, A., Agrawal, S., Mahoney, S., Gupta, D., Beca, J., Loftis, L., Morris, K., Piper, L., Slater, A., Walson, K., Bennett, T., Kilbaugh, T. & 39 others, Iqbal O'Meara, A. M., Dean, N., Chima, R. S., Biagas, K., Wildschut, E., Peters, M., LaRovere, K., Balcells, J., Robertson, C., Gertz, S., Deep, A., Cooper, S., Wainwright, M., Murphy, S., Kuluz, J., Butt, W., O'Brien, N., Thomas, N., Buttram, S., Erickson, S., Mahil Samuel, J., Agbeko, R., Edwards, R., Ramakrishnan, K. A., Winkler, M., Borasino, S., Natale, J., Giza, C., Hilfiker, M., Shellington, D., Figaji, A., Newell, E., Truemper, E., Clark, R., Newth, K., Shafi, N., Schober, M., Zimmerman, J. & Pineda, J., Apr 2019, In : Journal of Neurosurgery: Pediatrics. 23, 4, p. 471-479 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Vancomycin monotherapy may be insufficient to treat methicillin-resistant staphylococcus aureus coinfection in children with influenza-related critical illness

Randolph, A. G., Xu, R., Novak, T., Newhams, M. M., Wardenburg, J. B., Weiss, S. L., Sanders, R. C., Thomas, N. J., Hall, M. W., Tarquinio, K. M., Cvijanovich, N., Gedeit, R. G., Truemper, E. J., Markovitz, B., Hartman, M. E., Ackerman, K. G., Giuliano, J. S., Shein, S. L. & Moffitt, K. L., Jan 1 2019, In : Clinical Infectious Diseases. 68, 3, p. 365-372 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Vancomycin Prescribing and Therapeutic Drug Monitoring in Children With and Without Acute Kidney Injury After Cardiac Arrest

Fitzgerald, J. C., Zane, N. R., Himebauch, A. S., Reedy, M. D., Downes, K. J., Topjian, A. A., Furth, S. L., Thomas, N. J., Scheetz, M. H. & Zuppa, A. F., Jan 1 2019, In : Pediatric Drugs.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Age and Mortality in Pediatric Severe Traumatic Brain Injury: Results from an International Study

For the Investigators of the ADAPT Trial, Jun 1 2018, In : Neurocritical Care. 28, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Association of early postresuscitation hypotension with survival to discharge after targeted temperature management for pediatric out-of-hospital cardiac arrest secondary analysis of a randomized clinical trial

Topjian, A. A., Moler, F. W., Telford, R., Holubkov, R., Nadkarni, V. M., Berg, R. A., Dean, J. M., Meert, K. L., Hutchinson, J. S., Newth, C. J. L., Bennett, K. S., Berger, J. T., Pineda, J. A., Koch, J. D., Schleien, C. L., Dalton, H. J., Ofori-Amanfo, G., Goodman, D. M., Fink, E. L., McQuillen, P. & 24 others, Zimmerman, J. J., Thomas, N. J., Van Der Jagt, E. W., Porter, M. B., Meyer, M. T., Harrison, R., Pham, N., Schwarz, A. J., Nowak, J. E., Alten, J., Wheeler, D. S., Bhalala, U. S., Lidsky, K., Lloyd, E., Mathur, M., Shah, S., Wu, T., Theodorou, A. A., Sanders, R. C., Silverstein, F. S., Christensen, J. R., Slomine, B. S., Pemberton, V. L. & Browning, B., Feb 2018, In : JAMA Pediatrics. 172, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

CALIPSO: A Randomized Controlled Trial of Calfactant for Acute Lung Injury in Pediatric Stem Cell and Oncology Patients

for the CALIPSO Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators Network, Dec 2018, In : Biology of Blood and Marrow Transplantation. 24, 12, p. 2479-2486 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response

Wong, H. R., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J. C., Checchia, P. A., Meyer, K., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Lutfi, R., Gertz, S., Grunwell, J. R. & Lindsell, C. J., Mar 1 2018, In : Critical care medicine. 46, 3, p. e242-e249

Research output: Contribution to journalArticle

11 Scopus citations

Epidemiology of cause of death in pediatric acute respiratory distress syndrome

Dowell, J. C., Parvathaneni, K., Thomas, N. J., Khemani, R. G. & Yehya, N., Jan 1 2018, In : Critical care medicine. 46, 11, p. 1811-1819 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic association of pulmonary surfactant protein genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD with cystic fibrosis

Lin, Z., Thorenoor, N., Wut, R., Di Angelo, S. L., Ye, M., Thomas, N. J., Liao, X., Lin, T. R., Warren, S. & Floros, J., Oct 2 2018, In : Frontiers in immunology. 9, OCT, 2256.

Research output: Contribution to journalArticle

3 Scopus citations

Hospital Variation in Intensive Care Resource Utilization and Mortality in Newly Diagnosed Pediatric Leukemia

Fitzgerald, J. C., Li, Y., Fisher, B. T., Huang, Y. S., Miller, T. P., Bagatell, R., Seif, A. E., Aplenc, R. & Thomas, N. J., Jun 1 2018, In : Pediatric Critical Care Medicine. 19, 6, p. e312-e320

Research output: Contribution to journalArticle

3 Scopus citations

Hyperchloremia Is Associated with Complicated Course and Mortality in Pediatric Patients with Septic Shock

Stenson, E. K., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J. C., Checchia, P. A., Meyer, K., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Raj, S. S., Gertz, S., Grunwell, J. R. & Wong, H. R., Feb 1 2018, In : Pediatric Critical Care Medicine. 19, 2, p. 155-160 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Multicohort analysis of whole-blood gene expression data does not form a robust diagnostic for acute respiratory distress syndrome

Sweeney, T. E., Thomas, N. J., Howrylak, J. A., Wong, H. R., Rogers, A. J. & Khatri, P., Feb 2018, In : Critical care medicine. 46, 2, p. 244-251 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

New morbidity and discharge disposition of pediatric acute respiratory distress syndrome survivors

Keim, G., Scott Watson, R., Thomas, N. J. & Yehya, N., Jan 1 2018, In : Critical care medicine. 46, 11, p. 1731-1738 8 p.

Research output: Contribution to journalArticle

Overlapping MicroRNA Expression in Saliva and Cerebrospinal Fluid Accurately Identifies Pediatric Traumatic Brain Injury

Hicks, S. D., Johnson, J., Carney, M. C., Bramley, H., Olympia, R. P., Loeffert, A. C. & Thomas, N. J., Jan 1 2018, In : Journal of Neurotrauma. 35, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Platelet Transfusion Practices in Critically Ill Children

on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network, Pediatric Critical Care Blood Research Network (BloodNet) & The PT Investigators, Jan 1 2018, In : Critical care medicine. 46, 8, p. 1309-1317 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Positive end-expiratory pressure lower than the ards network protocol is associated with higher pediatric acute respiratory distress syndrome mortality

Khemani, R. G., Parvathaneni, K., Yehya, N., Bhalla, A. K., Thomas, N. J. & Newth, C. J. L., Jul 1 2018, In : American journal of respiratory and critical care medicine. 198, 1, p. 77-89 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

RBC Transfusions Are Associated with Prolonged Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome

Zubrow, M. E., Thomas, N. J., Friedman, D. F. & Yehya, N., Feb 1 2018, In : Pediatric Critical Care Medicine. 19, 2, p. e88-e96

Research output: Contribution to journalArticle

2 Scopus citations

Risk factors and inpatient outcomes associated with acute kidney injury at pediatric severe sepsis presentation

Fitzgerald, J. C., Ross, M. E., Thomas, N. J., Weiss, S. L., Balamuth, F. & Anderson, A. H., Oct 1 2018, In : Pediatric Nephrology. 33, 10, p. 1781-1790 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Risk Stratification Using Oxygenation in the First 24 Hours of Pediatric Acute Respiratory Distress Syndrome

Yehya, N., Thomas, N. J. & Khemani, R. G., Apr 1 2018, In : Critical care medicine. 46, 4, p. 619-624 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Site variability in regulatory oversight for an international study of pediatric sepsis

Sepsis Prevalence, Outcomes, and Therapy (SPROUT) Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators Network, Apr 1 2018, In : Pediatric Critical Care Medicine. 19, 4, p. e180-e188

Research output: Contribution to journalArticle

Subtypes of pediatric acute respiratory distress syndrome have different predictors of mortality

Yehya, N., Keim, G. & Thomas, N. J., Aug 1 2018, In : Intensive Care Medicine. 44, 8, p. 1230-1239 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

The association of nutrition status expressed as body mass index z score with outcomes in children with severe sepsis: A secondary analysis from the sepsis prevalence, outcomes, and therapies (SPROUT) study

Irving, S. Y., Daly, B., Verger, J., Typpo, K. V., Brown, A. M., Hanlon, A., Weiss, S. L., Fitzgerald, J. C., Nadkarni, V. M., Thomas, N. J., Srinivasan, V., Fontela, P., Tucci, M., Dumis-trascu, M., Skippen, P., Krahn, G., Bezares, E., Puig, G., Puig-Ramos, A., Garcia, R. & 79 others, Villar, M., Bigham, M., Polanski, T., Latifi, S., Giebner, D., Anthony, H., Hume, J., Galster, A., Linnerud, L., Sanders, R., Hefley, G., Madden, K., Thompson, A., Shein, S., Gertz, S., Han, Y., Williams, T., Hughes-Schalk, A., Chandler, H., Orioles, A., Zielinski, E., Doucette, A., Zebuhr, C., Wilson, T., Dimitriades, C., Ascani, J., Layburn, S., Valley, S., Markowitz, B., Terry, J., Morzov, R., Mcinnes, A., McArthur, J., Woods, K., Murkowski, K., Spaeder, M., Sharron, M., Wheeler, D., Beckman, E., Frank, E., Howard, K., Carroll, C., Nett, S., Jarvis, D., Patel, V., Higgerson, R., Christie, L., Typpo, K., Deschenes, J., Kirby, A., Uhl, T., Rehder, K., Cheifetz, I., Wrenn, S., Kypuros, K., Ackerman, K., Maffei, F., Bloomquist, G., Rizkalla, N., Kimura, D., Shah, S., Tigges, C., Su, F., Barlow, C., Michelson, K., Wolfe, K., Goodman, D., Campbell, L., Sorce, L., Bysani, K., Monjure, T., Evans, M., Totapally, B., Chegondi, M., Rodriguez, C., Frazier, J., Steele, L., Viteri, S. & Costarino, A., Jan 1 2018, In : Critical care medicine. 46, 11, p. e1029-e1039

Research output: Contribution to journalArticle

3 Scopus citations

Traumatic brain injury and infectious encephalopathy in children from four resource-limited settings in Africa

Fink, E. L., von Saint Andre‐von Arnim, A., Kumar, R., Wilson, P. T., Bacha, T., Aklilu, A. T., Teklemariam, T. L., Hooli, S., Tuyisenge, L., Otupiri, E., Fabio, A., Gianakas, J., Kochanek, P. M., Angus, D. C., Tasker, R. C., Cheifetz, I., Thomas, N., Thompson, A., Curley, M. A. Q., Jouvet, P. & 5 others, Markovitz, B., Nishisaki, A., Tucci, M., Watson, S. & Willson, D., Jul 2018, In : Pediatric Critical Care Medicine. 19, 7, p. 649-657 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Multiplex Electrochemical Biosensor for Bloodstream Infection Diagnosis

Gao, J., Jeffries, L., Mach, K. E., Craft, D. W., Thomas, N. J., Gau, V., Liao, J. C. & Wong, P. K., Aug 1 2017, In : SLAS Technology. 22, 4, p. 466-474 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

An Electrochemical Biosensor for Rapid Detection of Pediatric Bloodstream Infections

Kurundu Hewage, E. M. K., Spear, D., Umstead, T. M., Hu, S., Wang, M., Wong, P. K., Chroneos, Z. C., Halstead, E. S. & Thomas, N. J., Dec 1 2017, In : SLAS Technology. 22, 6, p. 616-625 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Association of Delayed Antimicrobial Therapy with One-Year Mortality in Pediatric Sepsis

Han, M., Fitzgerald, J. C., Balamuth, F., Keele, L., Alpern, E. R., Lavelle, J., Chilutti, M., Grundmeier, R. W., Nadkarni, V. M., Thomas, N. J. & Weiss, S. L., Jul 1 2017, In : Shock. 48, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Association of response to inhaled nitric oxide and duration of mechanical ventilation in pediatric acute respiratory distress syndrome

Dowell, J. C., Thomas, N. J. & Yehya, N., Nov 2017, In : Pediatric Critical Care Medicine. 18, 11, p. 1019-1026 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association of the haem oxygenase-1 gene with inflammatory bowel disease

Lin, Z., Hao, H., Hegarty, J. P., Lin, T. R., Wang, Y., Harris, L. R., Xu, H. N., Wu, R., Thomas, N. J. & Floros, J., Aug 2 2017, In : Swiss Medical Weekly. 147, w14456.

Research output: Contribution to journalArticle

1 Scopus citations

Challenges and opportunities for pediatric severe TBI—review of the evidence and exploring a way forward

for the Investigators of the ADAPT Study, Oct 1 2017, In : Child's Nervous System. 33, 10, p. 1663-1667 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
6 Scopus citations

Disassociating Lung Mechanics and Oxygenation in Pediatric Acute Respiratory Distress Syndrome

Yehya, N. & Thomas, N. J., Jul 1 2017, In : Critical care medicine. 45, 7, p. 1232-1239 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Genetic association and epistatic interaction of the interleukin-10 signaling pathway in pediatric inflammatory bowel disease

Lin, Z., Wang, Z., Hegarty, J. P., Lin, T. R., Wang, Y., Deiling, S., Wu, R., Thomas, N. J. & Floros, J., Jul 21 2017, In : World journal of gastroenterology. 23, 27, p. 4897-4909 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock

Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J., Checchia, P. A., Meyer, K., Quasney, M., Gedeit, R., Freishtat, R. J., Nowak, J., Raj, S. S., Gertz, S., Grunwell, J. R., Opoka, A. & Wong, H. R., Apr 1 2017, In : Pediatric Critical Care Medicine. 18, 4, p. 299-303 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

High Levels of Morbidity and Mortality among Pediatric Hematopoietic Cell Transplant Recipients with Severe Sepsis: Insights from the Sepsis PRevalence, OUtcomes, and Therapies International Point Prevalence Study

Sepsis PRevalence, OUtcomes, and Therapies Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Dec 1 2017, In : Pediatric Critical Care Medicine. 18, 12, p. 1114-1125 12 p.

Research output: Contribution to journalArticle

5 Scopus citations