• 1974 Citations
  • 23 h-Index
1986 …2019

Research output per year

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Research Output

2019

Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer

Willumsen, N., Ali, S. M., Leitzel, K., Drabick, J. J., Yee, N., Polimera, H. V., Nagabhairu, V., Krecko, L., Ali, A., Maddukuri, A., Moku, P., Ali, A., Poulose, J., Menon, H., Pancholy, N., Costa, L., Karsdal, M. A. & Lipton, A., Dec 1 2019, In : Scientific reports. 9, 1, 19761.

Research output: Contribution to journalArticle

Open Access

Correction to (The Lancet Gastroenterology & Hepatology (2019) 4(6) (454–465), (S2468125319300408), (10.1016/S2468-1253(19)30040-8))

on behalf of the RELIVE Investigators, Jul 1 2019, In : The Lancet Gastroenterology and Hepatology. 4, 7, p. e6

Research output: Contribution to journalComment/debate

Open Access

Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): a phase 3 randomised controlled trial

Merle, P., Blanc, J. F., Phelip, J. M., Pelletier, G., Bronowicki, J. P., Touchefeu, Y., Pageaux, G., Gerolami, R., Habersetzer, F., Nguyen-Khac, E., Casadei-Gardini, A., Borbath, I., Tran, A., Wege, H., Saad, A. S., Colombo, M., Abergel, A., Richou, C., Waked, I., Yee, N. S. & 73 others, Molé, A., Attali, P., Le Boulicaut, J., Vasseur, B., Moussata, D., Grangé, J. D., Ratziu, V., Khemissa-Akouz, F., Regnault, H., Dauvois, B., Zarski, J. P., Ollivier-Hourmand, I., Manfredi, S., Debette-Gratien, M., Gangloff, A., Fontanges, T., Baron, A., Bouattour, M., Vincent, J., Sieghart, W., Maieron, A., Peeters, M., Delwaide, J., Lasser, L., Berg, T., Schultheiß, M., Zipprich, A., Trojan, J., Ehmer, U., Luppi, G., Luca, G., Tamberi, S., Amoroso, D., Alabiso, O., Buonadonna, A., Toniutto, P., Tamburini, E., Cubillo, A., Muñoz, A., Guillén, C., Sánchez, G., Manzano, H., Navarro, V., Ales, I., Massuti, B., Dank, M., Bodoky, G., Kahan, Z., Horváth, Z., Gabrail, N., Ozer, H., Galanopoulos, C., Hauke, R., Raj, M., Harputluoglu, H., Sevinc, A., Goker, E., Coker, A., Yalcin, S., Ali, M., Ata, O., Tugba, I., ElKassas, M., Abdel, A., Wakid, I., Shamaa, S., El, N., Kohail, H., Makarem, J., Chehade, I., Farhat, F., López, C. & Marín, M., Jun 2019, In : The Lancet Gastroenterology and Hepatology. 4, 6, p. 454-465 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Enrichment of Extracellular Vesicles Via Lipid Nanoprobe-Functionalized Nanostructured Silica Microdevice

Wan, Y., Maurer, M., He, H. Z., Xia, Y. Q., Zhang, W. L., Hao, S. J., Yee, N. S. & Zheng, S. Y., Jun 2019, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII. Institute of Electrical and Electronics Engineers Inc., p. 273-276 4 p. 8808761. (2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Enrichment of extracellular vesicles with lipid nanoprobe functionalized nanostructured silica

Wan, Y., Maurer, M., He, H. Z., Xia, Y. Q., Hao, S. J., Zhang, W. L., Yee, N. S. & Zheng, S. Y., Jul 21 2019, In : Lab on a Chip. 19, 14, p. 2346-2355 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Special issue: Cancer biomarkers and targets in digestive organs

Yee, N. S. & Lee, N. P., Mar 1 2019, In : Biomedicines. 7, 1, 3.

Research output: Contribution to journalEditorial

Open Access
2018

Cemiplimab, a human monoclonal anti-PD-1, in patients (pts) with advanced or metastatic hepatocellular carcinoma (HCC): Data from an expansion cohort in a phase I study

Pishvaian, M. J., Weiss, G. J., Falchook, G. S., Yee, N., Gil-Martin, M., Shahda, S., Moreno, V., Brana, I., Crittenden, M., Formenti, S., Al-Rajabi, R., Papadopoulos, K. P., Stankevich, E., Feng, M., Li, J., Mathias, M., Kroog, G., Lowy, I. & Fury, M. G., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii410

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Molecular characterization of gastric carcinoma: Therapeutic implications for biomarkers and targets

Fonkoua, L. K. & Yee, N. S., Mar 1 2018, In : Biomedicines. 6, 1, 32.

Research output: Contribution to journalReview article

Open Access
22 Scopus citations

Tumor molecular profiling for an individualized approach to the treatment of hepatocellular carcinoma: A patient case study

Posadas, K., Ankola, A., Yang, Z. & Yee, N. S., Jun 1 2018, In : Biomedicines. 6, 2, 46.

Research output: Contribution to journalArticle

1 Scopus citations

Update in systemic and targeted therapies in gastrointestinal oncology

Yee, N. S., Mar 1 2018, In : Biomedicines. 6, 1, 34.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

Locally advanced unresectable pancreatic cancer: American Society of clinical oncology clinical practice guideline summary

Balaban, E., Mangu, P. B. & Yee, N. S-S., Apr 1 2017, In : Journal of Oncology Practice. 13, 4, p. 265-269 5 p.

Research output: Contribution to journalReview article

8 Scopus citations

Role of TRPM7 in cancer: Potential as molecular biomarker and therapeutic target

Yee, N. S., Apr 5 2017, In : Pharmaceuticals. 10, 2, 39.

Research output: Contribution to journalReview article

15 Scopus citations
2016

Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options

Ang, C., Miura, J. T., Clark Gamblin, T., He, R., Xiu, J., Millis, S. Z., Gatalica, Z., Reddy, S. K., Yee, N. S. & Abou-Alfa, G. K., Jan 1 2016, In : Journal of Surgical Oncology. 113, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Immunotherapeutic approaches in pancreatic adenocarcinoma: Current status and future perspectives

Yee, N. S., Aug 1 2016, In : Current Molecular Pharmacology. 9, 3, p. 231-241 11 p.

Research output: Contribution to journalReview article

4 Scopus citations

Locally advanced, unresectable pancreatic cancer: American society of clinical oncology clinical practice guideline

Balaban, E. P., Mangu, P. B., Khorana, A. A., Shah, M. A., Mukherjee, S., Crane, C. H., Javle, M. M., Eads, J. R., Allen, P., Ko, A. H., Engebretson, A., Herman, J. M., Strickler, J. H., Benson, A. B., Urba, S. & Yee, N. S., Aug 1 2016, In : Journal of Clinical Oncology. 34, 22, p. 2654-2667 14 p.

Research output: Contribution to journalArticle

133 Scopus citations

Molecular genetics and targeted therapeutics in biliary tract carcinoma

Marks, E. I. & Yee, N. S., Jan 28 2016, In : World journal of gastroenterology. 22, 4, p. 1335-1347 13 p.

Research output: Contribution to journalReview article

33 Scopus citations

Molecular genetics and targeted therapy in hepatocellular carcinoma

Marks, E. I. & Yee, N. S., Jan 1 2016, In : Current Cancer Drug Targets. 16, 1, p. 53-70 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

TRPM8 Ion Channels as Potential Cancer Biomarker and Target in Pancreatic Cancer

Yee, N. S., Jan 1 2016, Advances in Protein Chemistry and Structural Biology. Donev, R. (ed.). Academic Press Inc., p. 127-155 29 p. (Advances in Protein Chemistry and Structural Biology; vol. 104).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations
2015

Aberrant over-expression of TRPM7 ion channels in pancreatic cancer: Required for cancer cell invasion and implicated in tumor growth and metastasis

Yee, N. S., Kazi, A. A., Li, Q., Yang, Z., Berg, A. & Yee, R. K., Jan 1 2015, In : Biology Open. 4, 4, p. 507-514 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Advances in pharmacological treatment of cancer in digestive organs

Yee, N. S-S., Jan 1 2015, In : Current Clinical Pharmacology. 10, 4, p. 254-255 2 p.

Research output: Contribution to journalEditorial

Current systemic treatment and emerging therapeutic strategies in pancreatic adenocarcinoma

Yee, N. S., Kazi, A. A. & Yee, R. K., Jan 1 2015, In : Current Clinical Pharmacology. 10, 4, p. 256-266 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Immunotherapy in gastric carcinoma: Current status and future perspectives

Fonkoua, L. K. & Yee, N. S., Dec 1 2015, In : Clinical Cancer Drugs. 2, 2, p. 91-99 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites

El-Deiry, W. S., Vijayvergia, N., Xiu, J., Scicchitano, A., Lim, B., Yee, N. S., Harvey, H. A., Gatalica, Z. & Reddy, S., Dec 2 2015, In : Cancer Biology and Therapy. 16, 12, p. 1726-1737 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Roles of TRPM8 ion channels in cancer: Proliferation, survival, and invasion

Yee, N. S., Jan 1 2015, In : Cancers. 7, 4, p. 2134-2146 13 p., A13.

Research output: Contribution to journalReview article

29 Scopus citations

Systemic treatment of advanced biliary tract Carcinoma: Emerging roles of targeted therapy and molecular profiling

Wyluda, E. & Yee, N. S., Dec 1 2015, In : Clinical Cancer Drugs. 2, 2, p. 80-86 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Ion channels as novel pancreatic cancer biomarkers and targets

Yee, N. S. & Yee, R. K., Nov 1 2013, New Advances on Disease Biomarkers and Molecular Targets in Biomedicine. Humana Press Inc., p. 75-84 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): Results from a phase i clinical trial

Welsh, J. L., Wagner, B. A., Van'T Erve, T. J., Zehr, P. S., Berg, D. J., Halfdanarson, T. R., Yee, N. S., Bodeker, K. L., Du, J., Roberts, L. J., Drisko, J., Levine, M., Buettner, G. R. & Cullen, J. J., Mar 1 2013, In : Cancer Chemotherapy and Pharmacology. 71, 3, p. 765-775 11 p.

Research output: Contribution to journalArticle

128 Scopus citations

Toward the goal of personalized therapy in pancreatic cancer by targeting the molecular phenotype

Yee, N. S-S., Feb 15 2013, Impact of Genetic Targets on Cancer Therapy. El-Deiry, W. (ed.). p. 91-143 53 p. (Advances in Experimental Medicine and Biology; vol. 779).

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Translating discovery in zebrafish pancreatic development to human pancreatic cancer: Biomarkers, targets, pathogenesis, and therapeutics

Yee, N. S-S., Kazi, A. & Yee, R. K., Jun 1 2013, In : Zebrafish. 10, 2, p. 132-146 15 p.

Research output: Contribution to journalReview article

5 Scopus citations
2012

Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma

Yee, N. S., Zhou, W., Lee, M. & Yee, R. K., May 1 2012, In : Cancer Letters. 318, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Targeting developmental regulators of zebrafish exocrine pancreas as a therapeutic approach in human pancreatic cancer

Yee, N. S., Zhou, W., Chun, S. G., Liang, I. C. & Yee, R. K., Apr 15 2012, In : Biology Open. 1, 4, p. 295-307 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

The epigenetics of gastrointestinal malignancies

Hasanali, Z., Stuart, A., Yee, N. S-S., Sharma, K. & Epner, E., Dec 1 2012, In : Current Colorectal Cancer Reports. 8, 4, p. 254-262 9 p.

Research output: Contribution to journalReview article

3 Scopus citations

TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: Potential role of TRPM8 as a biomarker and target

Yee, N. S., Brown, R. D., Lee, M. S., Zhou, W., Jensen, C., Gerke, H. & Yee, R. K., Jun 2012, In : Cancer Biology and Therapy. 13, 8, p. 592-599 8 p.

Research output: Contribution to journalReview article

24 Scopus citations

TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target

Yee, N. S., Brown, R. D., Lee, M. S. U., Zhou, W., Jensen, C., Gerke, H. & Yee, R. K., Jun 1 2012, In : Cancer Biology and Therapy. 13, 8, p. 592-599 8 p.

Research output: Contribution to journalArticle

2011

Brca2 deficiency and Trp53 deregulation in pancreatic cancer: Implications for therapeutic targeting

Yee, N. S., Jun 1 2011, In : Cancer Biology and Therapy. 11, 11, p. 969-973 5 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer

Zhou, W., Liang, I. C. & Yee, N. S., Apr 1 2011, In : Cancer Biology and Therapy. 11, 7, p. 659-670 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Pancreatic adenocarcinoma associated with Werner's syndrome (adult-onset progeria)

Chun, S. G., Yee, N. S., Holland, J. M., Shohet, R. V., Palalay, M. P. & Bryant-Greenwood, P. K., Jan 1 2011, In : Gastrointestinal Cancer Research. 4, 1, p. 24-28 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
66 Scopus citations
2010

Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma

Yee, N. S., Zhou, W. & Lee, M., Nov 1 2010, In : Cancer Letters. 297, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

62 Scopus citations
14 Scopus citations

Zebrafish as a biological system for identifying and validating therapeutic targets and compounds

Yee, N. S-S., Dec 1 2010, Drug Discovery in Pancreatic Cancer: Models and Techniques. Springer New York, p. 95-112 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations
2009

Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer

Chun, S. G., Zhou, W. & Yee, N. S., Jul 15 2009, In : Cancer Biology and Therapy. 8, 14, p. 1328-1339 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer

Chun, S. G., Zhou, W. & Yee, N. S., Jul 15 2009, In : Cancer Biology and Therapy. 8, 14, p. 19-30 12 p.

Research output: Contribution to journalArticle

2007

Mutation of RNA Pol III subunit rpc2/polr3b leads to deficiency of subunit Rpc11 and disrupts zebrafish digestive development

Yee, N. S., Gong, W., Huang, Y., Lorent, K., Dolan, A. C., Maraia, R. J. & Pack, M., Nov 1 2007, In : PLoS biology. 5, 11, p. 2484-2492 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
2006

Clinical remission of acquired thrombasthenia with low-dose methotrexate in a patient with systemic lupus erythematosus [2]

Yee, N. S-S. & Schuster, S. J., Jan 1 2006, In : Mayo Clinic Proceedings. 81, 4, p. 566-567 2 p.

Research output: Contribution to journalLetter

6 Scopus citations
2005

Exocrine pancreas development in zebrafish

Yee, N. S., Lorent, K. & Pack, M., Aug 1 2005, In : Developmental biology. 284, 1, p. 84-101 18 p.

Research output: Contribution to journalArticle

86 Scopus citations

Zebrafish as a model for pancreatic cancer research.

Yee, N. S-S. & Pack, M., Jan 1 2005, In : Methods in molecular medicine. 103, p. 273-298 26 p.

Research output: Contribution to journalArticle

21 Scopus citations
2004

Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas

Lin, J. W., Biankin, A. V., Horb, M. E., Ghosh, B., Prasad, N. B., Yee, N. S., Pack, M. A. & Leach, S. D., Jun 15 2004, In : Developmental biology. 270, 2, p. 474-486 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.

Lin, J. W., Biankin, A. V., Horb, M. E., Ghosh, B., Prasad, N. B., Yee, N. S., Pack, M. A. & Leach, S. D., Oct 15 2004, In : Developmental biology. 274, 2, p. 491-503 13 p.

Research output: Contribution to journalComment/debate

55 Scopus citations