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Personal profile

Research interests

Dr. Nicholas Zaorsky is a radiation oncologist with three duties: delivery of excellent clinical care; leadership of the oncology research program; and education and mentorship of trainees. In the clinic, Dr. Zaorsky delivers multidisciplinary cancer care to patients, with expertise in the treatment of prostate cancer. He is the primary author of the American College of Radiology prostate cancer guidelines, the chief of our brachytherapy program, and editor of the textbooks Prostate Cancer: A Multidisciplinary Approach to Diagnosis and Management, and Absolute Clinical Radiation Oncology Review. Dr. Zaorsky’s research focuses on oncology-epidemiology, oncology guidelines (with the use of meta-analyses), radiobiology, and exercise therapy. He is the principal investigator of the Penn State clinical trial of exercise therapy + radiation therapy (EXERT). Dr. Zaorsky has mentored 20 trainees, most graduating with peer-reviewed publications. He is the Penn State site leader for the US Radiation Oncology Education Collaborative Study Group.

Education/Academic qualification

Radiation Oncology, Residency, Fox Chase Cancer Center


Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Radiotherapy Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Brachytherapy Medicine & Life Sciences
Radiation Oncology Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Comparative Effectiveness Research Medicine & Life Sciences

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Research Output 2012 2018

Ablative Hypofractionated Radiation Therapy Enhances Non-Small Cell Lung Cancer Cell Killing via Preferential Stimulation of Necroptosis In Vitro and In Vivo

Wang, H. H., Wu, Z. Q., Qian, D., Zaorsky, N. G., Qiu, M. H., Cheng, J. J., Jiang, C., Wang, J., Zeng, X. L., Liu, C. L., Tian, L. J., Ying, G. G., Meng, M. B., Hao, X. S. & Yuan, Z. Y., May 1 2018, In : International Journal of Radiation Oncology Biology Physics. 101, 1, p. 49-62 14 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
radiation therapy

Adult nodular lymphocyte-predominant Hodgkin lymphoma: treatment modality utilization and survival

Alonso, C., Dutta, S. W., Mitra, N., Landsburg, D. J., Zaorsky, N. G., Grover, S., Peterson, J. & Trifiletti, D. M., Apr 1 2018, In : Cancer medicine. 7, 4, p. 1118-1126 9 p.

Research output: Contribution to journalArticle

Hodgkin Disease
Drug Therapy
Propensity Score

Deviations From Standard Chemoradiation Among Early-Stage Anal Cancer Patients

Churilla, T. M., DeMora, L., Handorf, E., Zaorsky, N. G., Dong, Y., Denlinger, C. S., Sigurdson, E. R. & Meyer, J. E., Mar 15 2018, In : International Journal of Radiation Oncology Biology Physics. 100, 4, p. 945-949 5 p.

Research output: Contribution to journalArticle

Anus Neoplasms

Dose Escalation in Stereotactic Body Radiation Therapy for Pancreatic Cancer: A Meta-Analysis

Zaorsky, N. G., Lehrer, E. J., Handorf, E. & Meyer, J. E., Jun 30 2018, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Confidence Intervals
1 Citations

Effects of interruptions of external beam radiation therapy on outcomes in patients with prostate cancer

Dong, Y., Zaorsky, N. G., Li, T., Churilla, T. M., Viterbo, R., Sobczak, M. L., Smaldone, M. C., Chen, D. Y. T., Uzzo, R. G., Hallman, M. A. & Horwitz, E. M., Feb 1 2018, In : Journal of Medical Imaging and Radiation Oncology. 62, 1, p. 116-121 6 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Conformal Radiotherapy