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Research Output 1994 2020

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Article
2016
6 Citations (Scopus)

Gain-of-function mutation W493R in the epithelial sodium channel allosterically reconfigures intersubunit coupling

Shobair, M., Dagliyan, O., Kota, P., Dang, Y. L., He, H., Stutts, M. J. & Dokholyan, N. V., Feb 19 2016, In : Journal of Biological Chemistry. 291, 8, p. 3682-3692 11 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Molecular Dynamics Simulation
Water-Electrolyte Imbalance
Liddle Syndrome
Sodium
1 Citation (Scopus)

Harnessing Nature's Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins

Jacob, R. B., Michaels, K. C., Anderson, C. J., Fay, J. M. & Dokholyan, N. V., Nov 15 2016, In : Scientific reports. 6, 37175.

Research output: Contribution to journalArticle

Organophosphates
Organophosphate Poisoning
Molecular Weight
Acetylcholinesterase
Paraoxon
42 Citations (Scopus)

Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis

Proctor, E. A., Fee, L., Tao, Y., Redler, R. L., Fay, J. M., Zhang, Y., Lv, Z., Mercer, I. P., Deshmukh, M., Lyubchenko, Y. L. & Dokholyan, N. V., Jan 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 3, p. 614-619 6 p.

Research output: Contribution to journalArticle

Poisons
Amyotrophic Lateral Sclerosis
Motor Neurons
Mutation
Disease Progression
12 Citations (Scopus)

Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770

Gentzsch, M., Ren, H. Y., Houck, S. A., Quinney, N. L., Cholon, D. M., Sopha, P., Chaudhry, I. G., Das, J., Dokholyan, N. V., Randell, S. H. & Cyr, D. M., Jan 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 3, p. L550-L559

Research output: Contribution to journalArticle

Cystic Fibrosis
Mutation
Therapeutics
ivacaftor
lumacaftor
2015
11 Citations (Scopus)

ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations

Williams, B., Convertino, M., Das, J. & Dokholyan, N. V., Jan 1 2015, In : PLoS computational biology. 11, 10, e1004359.

Research output: Contribution to journalArticle

Apolipoprotein E4
Alzheimer's Disease
molecular dynamics
Molecular Dynamics Simulation
Alzheimer disease
9 Citations (Scopus)

Channel gating dependence on pore lining helix glycine residues in skeletal muscle ryanodine receptor

Mei, Y., Xu, L., Mowrey, D. D., Giraldez, R. M., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G., Jul 10 2015, In : Journal of Biological Chemistry. 290, 28, p. 17535-17545 11 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Linings
Glycine
Muscle
Skeletal Muscle
13 Citations (Scopus)

COMT gene locus: New functional variants

Meloto, C. B., Segall, S. K., Smith, S., Parisien, M., Shabalina, S. A., Rizzatti-Barbosa, C. M., Gauthier, J., Tsao, D., Convertino, M., Piltonen, M. H., Slade, G. D., Fillingim, R. B., Greenspan, J. D., Ohrbach, R., Knott, C., Maixner, W., Zaykin, D., Dokholyan, N. V., Reenila, I., Mannisto, P. T. & 1 others, Diatchenko, L., Oct 2015, In : Pain. 156, 10, p. 2072-2083 12 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Genes
Pain
Protein Isoforms
Adrenergic Agents
12 Citations (Scopus)

Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers

Martin, L. J., Piltonen, M. H., Gauthier, J., Convertino, M., Acland, E. L., Dokholyan, N., Mogil, J. S., Diatchenko, L. & Maixner, W., Jan 1 2015, In : Journal of Pain. 16, 12, p. 1321-1333 13 p.

Research output: Contribution to journalArticle

Bupranolol
Propranolol
Adrenergic Receptors
Adrenergic Agonists
Pain
9 Citations (Scopus)

Differential regulation of 6- and 7-Transmembrane helix variants of μ-opioid receptor in response to morphine stimulation

Convertino, M., Samoshkin, A., Viet, C. T., Gauthier, J., Fraine, S. P. L., Sharif-Naeini, R., Schmidt, B. L., Maixner, W., Diatchenko, L. & Dokholyan, N. V., Nov 10 2015, In : PloS one. 10, 11, e0142826.

Research output: Contribution to journalArticle

morphine
narcotics
Opioid Receptors
Morphine
Opioid Analgesics
25 Citations (Scopus)

iFoldRNA v2: Folding RNA with constraints

Krokhotin, A., Houlihan, K. & Dokholyan, N. V., Feb 6 2015, In : Bioinformatics. 31, 17, p. 2891-2893 3 p.

Research output: Contribution to journalArticle

RNA Folding
Folding
RNA
Servers
Server
20 Citations (Scopus)

Light-cleavable rapamycin dimer as an optical trigger for protein dimerization

Brown, K. A., Zou, Y., Shirvanyants, D., Zhang, J., Samanta, S., Mantravadi, P. K., Dokholyan, N. V. & Deiters, A., Apr 4 2015, In : Chemical Communications. 51, 26, p. 5702-5705 4 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Protein 1A
Dimerization
Sirolimus
Dimers
Proteins
9 Citations (Scopus)

Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX

Wang, L., Xie, L., Ramachandran, S., Lee, Y. Y., Yan, Z., Zhou, L., Krajewski, K., Liu, F., Zhu, C., Chen, D. J., Strahl, B. D., Jin, J., Dokholyan, N. V. & Chen, X., Jul 24 2015, In : Chemistry and Biology. 22, 7, p. 849-861 13 p., 3066.

Research output: Contribution to journalArticle

Lysine
DNA Damage
DNA
Radiation
Tumors
25 Citations (Scopus)

Rational coupled dynamics network manipulation rescues disease-relevant mutant cystic fibrosis transmembrane conductance regulator

Proctor, E. A., Kota, P., Aleksandrov, A. A., He, L., Riordan, J. R. & Dokholyan, N. V., Feb 1 2015, In : Chemical Science. 6, 2, p. 1237-1246 10 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Proteins
Ion Channels
Nucleotides
77 Citations (Scopus)

RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures

Miao, Z., Adamiak, R. W., Blanchet, M. F., Boniecki, M., Bujnicki, J. M., Chen, S. J., Cheng, C., Chojnowski, G., Chou, F. C., Cordero, P., Cruz, J. A., Ferré-D'Amaré, A. R., Das, R., Ding, F., Dokholyan, N. V., Dunin-Horkawicz, S., Kladwang, W., Krokhotin, A., Lach, G., Magnus, M. & 20 others, Major, F., Mann, T. H., Masquida, B., Matelska, D., Meyer, M., Peselis, A., Popenda, M., Purzycka, K. J., Serganov, A., Stasiewicz, J., Szachniuk, M., Tandon, A., Tian, S., Wang, J., Xiao, Y., Xu, X., Zhang, J., Zhao, P., Zok, T. & Westhof, E., Jun 1 2015, In : RNA (New York, N.Y.). 21, 6, p. 1066-1084 19 p.

Research output: Contribution to journalArticle

RNA
Riboswitch
RNA Folding
Catalytic RNA
Transfer RNA
15 Citations (Scopus)

Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling

Samoshkin, A., Convertino, M., Viet, C. T., Wieskopf, J. S., Kambur, O., Marcovitz, J., Patel, P., Stone, L. S., Kalso, E., Mogil, J. S., Schmidt, B. L., Maixner, W., Dokholyan, N. & Diatchenko, L., Dec 11 2015, In : Scientific reports. 5, 18198.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Adrenergic Receptors
Ligands
Calcium
14 Citations (Scopus)

μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids

Convertino, M., Samoshkin, A., Gauthier, J., Gold, M. S., Maixner, W., Dokholyan, N. & Diatchenko, L., Oct 1 2015, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 62, p. 61-67 7 p.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Protein Isoforms
Hyperalgesia
Second Messenger Systems
2014
23 Citations (Scopus)

Cu,Zn-superoxide dismutase without Zn is folded but catalytically inactive

Nedd, S., Redler, R. L., Proctor, E. A., Dokholyan, N. V. & Alexandrova, A. N., Dec 12 2014, In : Journal of Molecular Biology. 426, 24, p. 4112-4124 13 p.

Research output: Contribution to journalArticle

Protein Unfolding
Amyotrophic Lateral Sclerosis
Molecular Dynamics Simulation
Mechanics
Superoxides
175 Citations (Scopus)

Cystic fibrosis: Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

Cholon, D. M., Quinney, N. L., Fulcher, M. L., Esther, C. R., Das, J., Dokholyan, N. V., Randell, S. H., Boucher, R. C. & Gentzsch, M., Jul 23 2014, In : Science Translational Medicine. 6, 246, 246ra96.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Pharmacology
Mutation
Therapeutics
16 Citations (Scopus)

Discrete molecular dynamics can predict helical prestructured motifs in disordered proteins

Szöllosi, D., Horváth, T., Han, K. H., Dokholyan, N. V., Tompa, P., Kalmár, L. & Hegedus, T., Apr 24 2014, In : PloS one. 9, 4, e95795.

Research output: Contribution to journalArticle

molecular dynamics
Molecular Dynamics Simulation
Molecular dynamics
Intrinsically Disordered Proteins
Proteins
25 Citations (Scopus)

Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties

Thompson, P. M., Tolbert, C. E., Shen, K., Kota, P., Palmer, S. M., Plevock, K. M., Orlova, A., Galkin, V. E., Burridge, K., Egelman, E. H., Dokholyan, N., Superfine, R. & Campbell, S. L., May 6 2014, In : Structure. 22, 5, p. 697-706 10 p.

Research output: Contribution to journalArticle

Vinculin
Focal Adhesions
Cell Adhesion
Actins
Adherens Junctions
16 Citations (Scopus)

Intrinsic disorder mediates cooperative signal transduction in STIM1

Furukawa, Y., Teraguchi, S., Ikegami, T., Dagliyan, O., Jin, L., Hall, D., Dokholyan, N., Namba, K., Akira, S., Kurosaki, T., Baba, Y. & Standley, D. M., May 15 2014, In : Journal of Molecular Biology. 426, 10, p. 2082-2097 16 p.

Research output: Contribution to journalArticle

Signal Transduction
Dimerization
Structural Models
Ultracentrifugation
Endoplasmic Reticulum
18 Citations (Scopus)

Non-native soluble oligomers of Cu/Zn superoxide dismutase (SOD1) contain a conformational epitope linked to cytotoxicity in amyotrophic lateral sclerosis (ALS)

Redler, R. L., Fee, L., Fay, J. M., Caplow, M. & Dokholyan, N., Apr 15 2014, In : Biochemistry. 53, 14, p. 2423-2432 10 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Cytotoxicity
Oligomers
Epitopes
Poisons
6 Citations (Scopus)

Pore dynamics and conductance of RyR1 transmembrane domain

Shirvanyants, D., Ramachandran, S., Mei, Y., Xu, L., Meissner, G. & Dokholyan, N., Jun 3 2014, In : Biophysical journal. 106, 11, p. 2375-2384 10 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Central Core Myopathy
Cryoelectron Microscopy
Malignant Hyperthermia
Mutation
8 Citations (Scopus)

RNA tertiary structure analysis by 2?-Hydroxyl molecular interference

Homan, P. J., Tandon, A., Rice, G. M., Ding, F., Dokholyan, N. V. & Weeks, K. M., Nov 4 2014, In : Biochemistry. 53, 43, p. 6825-6833 9 p.

Research output: Contribution to journalArticle

Hydroxyl Radical
RNA
Guide RNA
Tetrahymena
Molecular Dynamics Simulation
53 Citations (Scopus)

Single-molecule correlated chemical probing of RNA

Homan, P. J., Favorov, O. V., Lavender, C. A., Kursun, O., Ge, X., Busan, S., Dokholyan, N. V. & Weeks, K. M., Sep 23 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13858-13863 6 p.

Research output: Contribution to journalArticle

RNA
RNA Folding
High-Throughput Nucleotide Sequencing
Nucleic Acids
Nucleotides
9 Citations (Scopus)

The maturation of HIV-1 protease precursor studied by discrete molecular dynamics

Kimura, S., Caldarini, M., Broglia, R. A., Dokholyan, N. V. & Tiana, G., Apr 2014, In : Proteins: Structure, Function and Bioinformatics. 82, 4, p. 633-639 7 p.

Research output: Contribution to journalArticle

Dimerization
Molecular Dynamics Simulation
Conformations
Molecular dynamics
Monomers
8 Citations (Scopus)

The N-terminal domain allosterically regulates cleavage and activation of the epthelial sodium channel

Kota, P., Buchner, G., Chakraborty, H., Dang, Y. L., He, H., Garcia, G. J. M., Kubelka, J., Gentzsch, M., Stutts, M. J. & Dokholyan, N. V., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 23029-23042 14 p.

Research output: Contribution to journalArticle

Sodium Channels
Peptide Hydrolases
Chemical activation
Phosphatidylinositols
Proteolysis
11 Citations (Scopus)

Traffic within the cytochrome b6f lipoprotein complex: Gating of the quinone portal

Hasan, S. S., Proctor, E. A., Yamashita, E., Dokholyan, N. V. & Cramer, W. A., Oct 7 2014, In : Biophysical journal. 107, 7, p. 1620-1628 9 p.

Research output: Contribution to journalArticle

Cytochrome b6f Complex
Hydroquinones
Lipoproteins
Superoxides
Oxidation-Reduction
2013
80 Citations (Scopus)

Correctors of δF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein

He, L., Kota, P., Aleksandrov, A. A., Cui, L., Jensen, T., Dokholyan, N. V. & Riordan, J. R., Feb 2013, In : FASEB Journal. 27, 2, p. 536-545 10 p.

Research output: Contribution to journalArticle

Mutant Proteins
Investigational Drugs
Proteolysis
Thermodynamics
Cystic Fibrosis
21 Citations (Scopus)

Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability

Chong, P. A., Kota, P., Dokholyan, N. V. & Forman-Kay, J. D., Mar 1 2013, In : Cold Spring Harbor Perspectives in Medicine. 3, 3, a009522.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Nucleotides
Excited states
Sampling
Phosphorylation
4 Citations (Scopus)

Highly covarying residues have a functional role in antibody constant domains

Proctor, E. A., Kota, P., Demarest, S. J., Caravella, J. A. & Dokholyan, N. V., May 1 2013, In : Proteins: Structure, Function and Bioinformatics. 81, 5, p. 884-895 12 p.

Research output: Contribution to journalArticle

Antibodies
Mutation
Proteins
Antibody Specificity
Immunoglobulin Isotypes
12 Citations (Scopus)

Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): Structural and thermodynamic basis of CIB1 promiscuity

Freeman, T. C., Black, J. L., Bray, H. G., Dagliyan, O., Wu, Y. I., Tripathy, A., Dokholyan, N. V., Leisner, T. M. & Parise, L. V., Oct 8 2013, In : Biochemistry. 52, 40, p. 7082-7090 9 p.

Research output: Contribution to journalArticle

Calcium-Binding Proteins
Thermodynamics
Integrins
Carrier Proteins
Calcium
27 Citations (Scopus)
flexibility
Ligands
drug
ranking
Conformations
32 Citations (Scopus)

Knowledge-based design of a biosensor to quantify localized ERK activation in living cells

Kummer, L., Hsu, C. W., Dagliyan, O., MacNevin, C., Kaufholz, M., Zimmermann, B., Dokholyan, N. V., Hahn, K. M. & Plückthun, A., Jun 20 2013, In : Chemistry and Biology. 20, 6, p. 847-856 10 p.

Research output: Contribution to journalArticle

Biosensing Techniques
Biosensors
Chemical activation
Cells
Fibroblasts

Metric to distinguish closely related domain families using sequence information

Proctor, E. A., Kota, P., Demarest, S. J., Caravella, J. A. & Dokholyan, N., Feb 8 2013, In : Journal of Molecular Biology. 425, 3, p. 475-478 4 p.

Research output: Contribution to journalArticle

Antibodies
Immunoglobulin Variable Region
Immunoglobulin Isotypes
Histocompatibility Antigens Class II
Entropy
17 Citations (Scopus)

Predicting binding affinity of CSAR ligands using both structure-based and ligand-based approaches

Fourches, D., Muratov, E., Ding, F., Dokholyan, N. V. & Tropsha, A., Aug 26 2013, In : Journal of Chemical Information and Modeling. 53, 8, p. 1915-1922 8 p.

Research output: Contribution to journalArticle

ranking
Ligands
predictive model
performance
Binders
25 Citations (Scopus)

Principles for understanding the accuracy of SHAPE-directed RNA structure modeling

Leonard, C. W., Hajdin, C. E., Karabiber, F., Mathews, D. H., Favorov, O. V., Dokholyan, N. V. & Weeks, K. M., Jan 29 2013, In : Biochemistry. 52, 4, p. 588-595 8 p.

Research output: Contribution to journalArticle

Acylation
Hydroxyl Radical
RNA
Riboswitch
RNA, Transfer, Phe
2 Citations (Scopus)

Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family

Barison, N., Cendron, L., Loconte, V., Proctor, E. A., Dokholyan, N. V. & Zanotti, G., Aug 1 2013, In : Acta Crystallographica Section D: Biological Crystallography. 69, 8, p. 1387-1394 8 p.

Research output: Contribution to journalArticle

Lipocalins
Helicobacter pylori
Periplasm
Proteins
Bacteria
53 Citations (Scopus)

Rational design of a ligand-controlled protein conformational switch

Dagliyan, O., Shirvanyants, D., Karginov, A. V., Ding, F., Fee, L., Chandrasekaran, S. N., Freisinger, C. M., Smolen, G. A., Huttenlocher, A., Hahn, K. M. & Dokholyan, N. V., Apr 23 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 17, p. 6800-6804 5 p.

Research output: Contribution to journalArticle

src-Family Kinases
Ligands
Protein Engineering
Proteins
Zebrafish
9 Citations (Scopus)

Statistical analysis of SHAPE-directed RNA secondary structure modeling

Ramachandran, S., Ding, F., Weeks, K. M. & Dokholyan, N. V., Jan 29 2013, In : Biochemistry. 52, 4, p. 596-599 4 p.

Research output: Contribution to journalArticle

Acylation
Hydroxyl Radical
Statistical methods
RNA
Systematic errors
36 Citations (Scopus)

Structural determinants of skeletal muscle ryanodine receptor gating

Ramachandran, S., Chakraborty, A., Xu, L., Mei, Y., Samsó, M., Dokholyan, N. V. & Meissner, G., Mar 1 2013, In : Journal of Biological Chemistry. 288, 9, p. 6154-6165 12 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Muscle
Skeletal Muscle
Structural Models
Linings
13 Citations (Scopus)

Submillisecond elastic recoil reveals molecular origins of fibrin fiber mechanics

Hudson, N. E., Ding, F., Bucay, I., O'Brien, E. T., Gorkun, O. V., Superfine, R., Lord, S. T., Dokholyan, N. & Falvo, M. R., Jun 18 2013, In : Biophysical journal. 104, 12, p. 2671-2680 10 p.

Research output: Contribution to journalArticle

Mechanics
Fibrin
Elasticity
Molecular Models
Protein Refolding
2012
56 Citations (Scopus)

Allosteric modulation balances thermodynamic stability and restores function of Δf508 CFTR

Aleksandrov, A. A., Kota, P., Cui, L., Jensen, T., Alekseev, A. E., Reyes, S., He, L., Gentzsch, M., Aleksandrov, L. A., Dokholyan, N. V. & Riordan, J. R., May 25 2012, In : Journal of Molecular Biology. 419, 1-2, p. 41-60 20 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Thermodynamics
Proline
Genetic Suppression
Transition Temperature
26 Citations (Scopus)
Molecular mechanics
mechanic
Screening
knowledge
Ligands
94 Citations (Scopus)

Discrete molecular dynamics: An efficient and versatile simulation method for fine protein characterization

Shirvanyants, D., Ding, F., Tsao, D., Ramachandran, S. & Dokholyan, N. V., Jul 26 2012, In : Journal of Physical Chemistry B. 116, 29, p. 8375-8382 8 p.

Research output: Contribution to journalArticle

folding
Molecular dynamics
molecular dynamics
proteins
Proteins
25 Citations (Scopus)

Discrete molecular dynamics distinguishes nativelike binding poses from decoys in difficult targets

Proctor, E. A., Yin, S., Tropsha, A. & Dokholyan, N., Jan 4 2012, In : Biophysical Journal. 102, 1, p. 144-151 8 p.

Research output: Contribution to journalArticle

Molecular Dynamics Simulation
Ligands
Small Molecule Libraries
Drug Discovery
Proteins
13 Citations (Scopus)

Energetic and structural basis for activation of the epithelial sodium channel by matriptase

Kota, P., García-Caballero, A., Dang, H., Gentzsch, M., Stutts, M. J. & Dokholyan, N. V., Apr 24 2012, In : Biochemistry. 51, 16, p. 3460-3469 10 p.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Peptide Hydrolases
Chemical activation
Furin
Endopeptidases
44 Citations (Scopus)

Harnessing a physiologic mechanism for siRNA delivery with mimetic lipoprotein particles

Nakayama, T., Butler, J. S., Sehgal, A., Severgnini, M., Racie, T., Sharman, J., Ding, F., Morskaya, S. S., Brodsky, J., Tchangov, L., Kosovrasti, V., Meys, M., Nechev, L., Wang, G., Peng, C. G., Fang, Y., Maier, M., Rajeev, K. G., Li, R., Hettinger, J. & 11 others, Barros, S., Clausen, V., Zhang, X., Wang, Q., Hutabarat, R., Dokholyan, N. V., Wolfrum, C., Manoharan, M., Kotelianski, V., Stoffel, M. & Sah, D. W. Y., Aug 1 2012, In : Molecular Therapy. 20, 8, p. 1582-1589 8 p.

Research output: Contribution to journalArticle

Lip
Small Interfering RNA
Lipoproteins
Apolipoprotein E3
Apolipoprotein A-I
17 Citations (Scopus)

Hybrid dynamics simulation engine for metalloproteins

Sparta, M., Shirvanyants, D., Ding, F., Dokholyan, N. V. & Alexandrova, A. N., Aug 22 2012, In : Biophysical journal. 103, 4, p. 767-776 10 p.

Research output: Contribution to journalArticle

Metalloproteins
Molecular Dynamics Simulation
Catalytic Domain
Proteins
Rubredoxins
4 Citations (Scopus)

Intra- and inter-subunit disulfide bond formation is nonessential in adeno-associated viral capsids

Pulicherla, N., Kota, P., Dokholyan, N. V. & Asokan, A., Feb 28 2012, In : PloS one. 7, 2, e32163.

Research output: Contribution to journalArticle

Dependovirus
capsid
Capsid
disulfide bonds
Viruses