• 975 Citations
  • 18 h-Index
20102020

Research output per year

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Personal profile

Research interests

Nearly 80 percent of adults in the United States with an alcohol use disorder also use nicotine in various forms. The lab of Dr. Patrick Randall focuses on gaining a better understanding of the underlying neurobiology that leads to and maintains nicotine and alcohol co-use.

Of particular interest is the role that the neuroimmune system plays in co-use. Dr. Randall and his colleagues have previously demonstrated that a single immune challenge produces both rapid and lasting changes to not only markers of immune function but also changes in brain regions related to drug-seeking behavior and corresponding increases in alcohol self-administration.

Dr. Randall has also previously shown through drug discrimination models that, when nicotine and alcohol are used in combination, they are perceived differently from either drug on its own, suggesting that the experience of using both is unique and an important factor in understanding co-use.

The Randall lab uses a variety of techniques, including comprehensive behavioral models and viral techniques, to probe the role of specific brain circuitry in addiction.

Education/Academic qualification

Research Associate, Bowles Center for Alcohol Studies

Oct 2017May 2019

Postdoctoral Fellowship, Bowles Center for Alcohol Studies

Oct 2013Oct 2017

Psychology - Behavioral Neuroscience, PhD, University of Connecticut

May 2008Oct 2013

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Research Output

  • 975 Citations
  • 18 h-Index
  • 26 Article
  • 2 Review article
  • 1 Chapter

Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development

LeCocq, M. R., Randall, P. A., Besheer, J. & Chaudhri, N., Jan 1 2020, In : Neurotherapeutics. 17, 1, p. 43-54 12 p.

Research output: Contribution to journalReview article

  • 1 Scopus citations

    Role of mPFC and nucleus accumbens circuitry in modulation of a nicotine plus alcohol compound drug state

    Randall, P. A., McElligott, Z. A. & Besheer, J., Jul 1 2020, In : Addiction Biology. 25, 4, e12782.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Effects of nicotine conditioning history on alcohol and methamphetamine self-administration in rats

    Randall, P. A., Fortino, B., Huynh, Y. W., Thompson, B. M., Larsen, C. E., Callen, M. P., Barrett, S. T., Murray, J. E., Bevins, R. A. & Besheer, J., Apr 2019, In : Pharmacology Biochemistry and Behavior. 179, p. 1-8 8 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations
  • 7 Scopus citations

    Functional role for cortical-striatal circuitry in modulating alcohol self-administration

    Jaramillo, A. A., Randall, P. A., Stewart, S., Fortino, B., Van Voorhies, K. & Besheer, J., Mar 1 2018, In : Neuropharmacology. 130, p. 42-53 12 p.

    Research output: Contribution to journalArticle

  • 19 Scopus citations