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Philip C. Bevilacqua

    • United States

    • 5648 Citations
    • 42 h-Index
    1989 …2023
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    • 3 Similar Profiles
    Catalytic RNA Medicine & Life Sciences
    RNA Medicine & Life Sciences
    Hepatitis Delta Virus Medicine & Life Sciences
    RNA Folding Medicine & Life Sciences
    Base Pairing Medicine & Life Sciences
    Viruses Chemical Compounds
    Thermodynamics Medicine & Life Sciences
    eIF-2 Kinase Medicine & Life Sciences

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    Projects 1999 2023

    RNA folding and catalysis at the interface of biophysics and genomics

    Bevilacqua, P. C.

    National Institutes of Health

    5/1/18 → 4/30/23

    Project: Research project › Outstanding Investigator Award

    RNA Folding
    Biophysics
    Genomics
    Catalysis
    Catalytic RNA

    RNA Folding and Adaptation in a Cellular Context

    Bevilacqua, P. C.

    National Institutes of Health

    8/1/14 → 4/30/19

    Project: Research project › Research Project

    RNA Folding
    RNA
    Cytoplasm
    Guide RNA
    Riboswitch

    FASEB 2010 Meeting On Nucleic Acid Enzymes

    Bevilacqua, P. C.

    National Institutes of Health

    5/1/10 → 4/30/11

    Project: Research project › Conference

    Nucleic Acids
    RNA
    Posters
    Enzymes
    Research Personnel

    MECHANISM FOR REGULATION OF PKR PROTEIN BY RNA

    Bevilacqua, P. C.

    National Institutes of Health

    1/1/99 → 2/28/13

    Project: Research project › Research Project

    RNA
    Hepatitis Delta Virus
    RNA Folding
    Nucleotide Motifs
    Proteins

    Research Output 1989 2018

    1 Citations

    Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

    Yamagami, R., Bingaman, J. L., Frankel, E. A. & Bevilacqua, P. C., Dec 1 2018, In : Nature Communications. 9, 1, 2149.

    Research output: Contribution to journal › Article

    RNA Stability
    Chelating Agents
    Metabolites
    Catalysis
    Magnesium

    Cellular Small Molecules Contribute to Twister Ribozyme Catalysis

    Messina, K. J. & Bevilacqua, P. C., Aug 22 2018, In : Journal of the American Chemical Society. 140, 33, p. 10578-10582 5 p.

    Research output: Contribution to journal › Article

    Catalytic RNA
    Catalysis
    Molecules
    Buffers
    Amino sugars
    2 Citations

    Complexity in pH-Dependent Ribozyme Kinetics: Dark pKa Shifts and Wavy Rate-pH Profiles

    Frankel, E. A. & Bevilacqua, P. C., Feb 6 2018, In : Biochemistry. 57, 5, p. 483-488 6 p.

    Research output: Contribution to journal › Review article

    Catalytic RNA
    Catalysis
    RNA
    Protons
    Protonation
    3 Citations

    Elucidation of Catalytic Strategies of Small Nucleolytic Ribozymes from Comparative Analysis of Active Sites

    Seith, D. D., Bingaman, J. L., Veenis, A. J., Button, A. C. & Bevilacqua, P. C., Jan 5 2018, In : ACS Catalysis. 8, 1, p. 314-327 14 p.

    Research output: Contribution to journal › Article

    Catalytic RNA
    Catalysis
    Nucleophiles
    Hydrogen bonds
    Amidines
    3 Citations

    Glyoxals as in vivo RNA structural probes of guanine base-pairing

    Mitchell, D., Ritchey, L. E., Park, H., Babitzke, P. L., Assmann, S. M. & Bevilacqua, P. C., Jan 1 2018, In : RNA. 24, 1, p. 114-124 11 p.

    Research output: Contribution to journal › Article

    RNA Probes
    Cytosine
    Guanine
    Adenine
    Base Pairing