Philip C. Bevilacqua

    • United States

    • 5648 Citations
    • 42 h-Index
    1989 …2023
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    • 3 Similar Profiles
    Catalytic RNA Medicine & Life Sciences
    RNA Medicine & Life Sciences
    Hepatitis Delta Virus Medicine & Life Sciences
    RNA Folding Medicine & Life Sciences
    Base Pairing Medicine & Life Sciences
    Viruses Chemical Compounds
    Thermodynamics Medicine & Life Sciences
    eIF-2 Kinase Medicine & Life Sciences

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    Projects 1999 2023

    RNA folding and catalysis at the interface of biophysics and genomics

    Bevilacqua, P. C.

    National Institutes of Health

    5/1/184/30/23

    Project: Research projectOutstanding Investigator Award

    RNA Folding
    Biophysics
    Genomics
    Catalysis
    Catalytic RNA

    RNA Folding and Adaptation in a Cellular Context

    Bevilacqua, P. C.

    National Institutes of Health

    8/1/144/30/19

    Project: Research projectResearch Project

    RNA Folding
    RNA
    Cytoplasm
    Guide RNA
    Riboswitch
    Nucleic Acids
    RNA
    Posters
    Enzymes
    Research Personnel

    MECHANISM FOR REGULATION OF PKR PROTEIN BY RNA

    Bevilacqua, P. C.

    National Institutes of Health

    1/1/992/28/13

    Project: Research projectResearch Project

    RNA
    Hepatitis Delta Virus
    RNA Folding
    Nucleotide Motifs
    Proteins

    Research Output 1989 2018

    1 Citations

    Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

    Yamagami, R., Bingaman, J. L., Frankel, E. A. & Bevilacqua, P. C., Dec 1 2018, In : Nature Communications. 9, 1, 2149.

    Research output: Contribution to journalArticle

    RNA Stability
    Chelating Agents
    Metabolites
    Catalysis
    Magnesium

    Cellular Small Molecules Contribute to Twister Ribozyme Catalysis

    Messina, K. J. & Bevilacqua, P. C., Aug 22 2018, In : Journal of the American Chemical Society. 140, 33, p. 10578-10582 5 p.

    Research output: Contribution to journalArticle

    Catalytic RNA
    Catalysis
    Molecules
    Buffers
    Amino sugars
    2 Citations

    Complexity in pH-Dependent Ribozyme Kinetics: Dark pKa Shifts and Wavy Rate-pH Profiles

    Frankel, E. A. & Bevilacqua, P. C., Feb 6 2018, In : Biochemistry. 57, 5, p. 483-488 6 p.

    Research output: Contribution to journalReview article

    Catalytic RNA
    Catalysis
    RNA
    Protons
    Protonation
    3 Citations

    Elucidation of Catalytic Strategies of Small Nucleolytic Ribozymes from Comparative Analysis of Active Sites

    Seith, D. D., Bingaman, J. L., Veenis, A. J., Button, A. C. & Bevilacqua, P. C., Jan 5 2018, In : ACS Catalysis. 8, 1, p. 314-327 14 p.

    Research output: Contribution to journalArticle

    Catalytic RNA
    Catalysis
    Nucleophiles
    Hydrogen bonds
    Amidines
    3 Citations

    Glyoxals as in vivo RNA structural probes of guanine base-pairing

    Mitchell, D., Ritchey, L. E., Park, H., Babitzke, P. L., Assmann, S. M. & Bevilacqua, P. C., Jan 1 2018, In : RNA. 24, 1, p. 114-124 11 p.

    Research output: Contribution to journalArticle

    RNA Probes
    Cytosine
    Guanine
    Adenine
    Base Pairing