Philip C. Bevilacqua

    • United States

    • 5739 Citations
    • 43 h-Index
    1989 …2023
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    • 4 Similar Profiles
    Catalytic RNA Medicine & Life Sciences
    RNA Medicine & Life Sciences
    Hepatitis Delta Virus Medicine & Life Sciences
    RNA Folding Medicine & Life Sciences
    Base Pairing Medicine & Life Sciences
    Viruses Chemical Compounds
    Thermodynamics Medicine & Life Sciences
    eIF-2 Kinase Medicine & Life Sciences

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    Projects 1999 2023

    RNA folding and catalysis at the interface of biophysics and genomics

    Bevilacqua, P. C.

    National Institutes of Health

    5/1/184/30/23

    Project: Research projectOutstanding Investigator Award

    RNA Folding
    Biophysics
    Genomics
    Catalysis
    Catalytic RNA

    RNA Folding and Adaptation in a Cellular Context

    Bevilacqua, P. C.

    National Institutes of Health

    8/1/144/30/19

    Project: Research projectResearch Project

    RNA Folding
    RNA
    Cytoplasm
    Guide RNA
    Riboswitch
    Nucleic Acids
    RNA
    Posters
    Enzymes
    Research Personnel

    MECHANISM FOR REGULATION OF PKR PROTEIN BY RNA

    Bevilacqua, P. C.

    National Institutes of Health

    1/1/992/28/13

    Project: Research projectResearch Project

    RNA
    Hepatitis Delta Virus
    RNA Folding
    Nucleotide Motifs
    Proteins

    Research Output 1989 2019

    Design of highly active double-pseudoknotted ribozymes: a combined computational and experimental study

    Yamagami, R., Kayedkhordeh, M., Mathews, D. H. & Bevilacqua, P. C., Jan 10 2019, In : Nucleic acids research. 47, 1, p. 29-42 14 p.

    Research output: Contribution to journalArticle

    Catalytic RNA
    RNA Folding
    Riboswitch
    RNA
    Synthetic Biology

    In vivo RNA structural probing of uracil and guanine base-pairing by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)

    Mitchell, D., Renda, A. J., Douds, C. A., Babitzke, P. L., Assmann, S. M. & Bevilacqua, P. C., Jan 1 2019, In : RNA. 25, 1, p. 147-157 11 p.

    Research output: Contribution to journalArticle

    Ethyldimethylaminopropyl Carbodiimide
    Uracil
    Guanine
    Base Pairing
    Glyoxal
    2 Citations

    Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis

    Yamagami, R., Bingaman, J. L., Frankel, E. A. & Bevilacqua, P. C., Dec 1 2018, In : Nature Communications. 9, 1, 2149.

    Research output: Contribution to journalArticle

    RNA Stability
    Catalysis
    Magnesium
    catalysis
    amino acids

    Cellular Small Molecules Contribute to Twister Ribozyme Catalysis

    Messina, K. J. & Bevilacqua, P. C., Aug 22 2018, In : Journal of the American Chemical Society. 140, 33, p. 10578-10582 5 p.

    Research output: Contribution to journalArticle

    Catalytic RNA
    Catalysis
    Molecules
    Buffers
    Amino sugars
    3 Citations

    Complexity in pH-Dependent Ribozyme Kinetics: Dark pKa Shifts and Wavy Rate-pH Profiles

    Frankel, E. A. & Bevilacqua, P. C., Feb 6 2018, In : Biochemistry. 57, 5, p. 483-488 6 p.

    Research output: Contribution to journalReview article

    Catalytic RNA
    Catalysis
    RNA
    Protons
    Protonation