• 1708 Citations
  • 21 h-Index
1984 …2020

Research output per year

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Research Output

  • 1708 Citations
  • 21 h-Index
  • 51 Article
  • 5 Review article
  • 2 Chapter
  • 1 Comment/debate
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Article
2020
Open Access

Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats

Komninou, D., Malloy, V. L., Zimmerman, J. A., Sinha, R. & Richie, J. P., Feb 1 2020, In : GeroScience. 42, 1, p. 287-297 11 p.

Research output: Contribution to journalArticle

Pan-cancer mapping of differential protein-protein interactions

Gulfidan, G., Turanli, B., Beklen, H., Sinha, R. & Arga, K. Y., Dec 1 2020, In : Scientific reports. 10, 1, 3272.

Research output: Contribution to journalArticle

Open Access
2019

Multi-omic data interpretation to repurpose subtype specific drug candidates for breast cancer

Turanli, B., Karagoz, K., Bidkhori, G., Sinha, R., Gatza, M. L., Uhlen, M., Mardinoglu, A. & Arga, K. Y., Jan 1 2019, In : Frontiers in Genetics. 10, MAY, 420.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice

Soni, C., Sinha, I., Fasnacht, M. J., Olsen, N., Rahman, Z. & Sinha, R., Feb 17 2019, In : Autoimmunity. 52, 2, p. 57-68 12 p.

Research output: Contribution to journalArticle

2018

Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function

Sinha, R., Sinha, I., Calcagnotto, A., Trushin, N., Haley, J. S., Schell, T. D. & Richie, J. P., Jan 1 2018, In : European Journal of Clinical Nutrition. 72, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Comprehensive geriatric assessment in 326 older women with early breast cancer

Okonji, D. O., Sinha, R., Phillips, I., Fatz, D. & Ring, A., Sep 26 2017, In : British Journal of Cancer. 117, 7, p. 925-931 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ovarian Cancer Differential Interactome and Network Entropy Analysis Reveal New Candidate Biomarkers

Ayyildiz, D., Gov, E., Sinha, R. & Arga, K. Y., May 2017, In : OMICS A Journal of Integrative Biology. 21, 5, p. 285-294 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice, [BMC Cancer., 16, (2016): 349] doi: 10.1186/s12885-016-2367-1

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jul 14 2016, In : BMC Cancer. 16, 1, 474.

Research output: Contribution to journalArticle

Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Hens, J. R., Sinha, I., Perodin, F., Cooper, T., Sinha, R., Plummer, J., Perrone, C. E. & Orentreich, D., Jun 3 2016, In : BMC Cancer. 16, 1, 349.

Research output: Contribution to journalArticle

14 Scopus citations

"Omics" of Selenium Biology: A Prospective Study of Plasma Proteome Network before and after Selenized-Yeast Supplementation in Healthy Men

Sinha, I., Karagoz, K., Fogle, R. L., Hollenbeak, C. S., Zea, A. H., Arga, K. Y., Stanley, A. E., Hawkes, W. C. & Sinha, R., Apr 1 2016, In : OMICS A Journal of Integrative Biology. 20, 4, p. 202-213 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Proteomic and metabolic signatures of esophageal squamous cell carcinoma

Karagoz, K., Lehman, H. L., Stairs, D. B., Sinha, R. & Arga, K. Y., Oct 1 2016, In : Current Cancer Drug Targets. 16, 8, p. 721-736 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Triple negative breast cancer: A multi-omics network discovery strategy for candidate targets and driving pathways

Karagoz, K., Sinha, R. & Arga, K. Y., Feb 1 2015, In : OMICS A Journal of Integrative Biology. 19, 2, p. 115-130 16 p.

Research output: Contribution to journalArticle

43 Scopus citations
2014

Comparative effects of two different forms of selenium on oxidative stress biomarkers in healthy men: A randomized clinical trial

Richie, J. P., Das, A., Calcagnotto, A. M., Sinha, R., Neidig, W., Liao, J., Lengerich, E. J., Berg, A., Hartman, T. J., Ciccarella, A., Baker, A., Kaag, M. G., Goodin, S., DiPaola, R. S. & El-Bayoumy, K., Aug 2014, In : Cancer Prevention Research. 7, 8, p. 796-804 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice

Sinha, R., Cooper, T., Rogers, C. J., Sinha, I., Turbitt, W. J., Calcagnotto, A., Perrone, C. E. & Richie, J., Jan 1 2014, In : Prostate. 74, 16, p. 1663-1673 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia

Sinha, I., Allen, J. E., Pinto, J. T. & Sinha, R., Apr 1 2014, In : Cancer medicine. 3, 2, p. 252-264 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Methionine restriction affects oxidative stress and glutathione-related redox pathways in the rat

Maddineni, S., Nichenametla, S., Sinha, R., Wilson, R. P. & Richie, J. P., Jul 25 2013, In : Experimental Biology and Medicine. 238, 4, p. 392-399 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer

Sinha, I., Null, K., Wolter, W., Suckow, M. A., King, T., Pinto, J. T. & Sinha, R., Mar 15 2012, In : International Journal of Cancer. 130, 6, p. 1430-1439 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
21 Scopus citations

Single-step nanoplasmonic VEGF 165 aptasensor for early cancer diagnosis

Cho, H., Yeh, E. C., Sinha, R., Laurence, T. A., Bearinger, J. P. & Lee, L. P., Sep 25 2012, In : ACS nano. 6, 9, p. 7607-7614 8 p.

Research output: Contribution to journalArticle

87 Scopus citations
3 Scopus citations
2010
26 Scopus citations

Selenium-responsive proteins in the sera of selenium-enriched yeast-supplemented healthy African American and Caucasian men

Sinha, R., Sinha, I., Facompre, N., Russell, S., Somiari, R. I., Richie, J. P. & El-Bayoumy, K., Sep 1 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 9, p. 2332-2340 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cells

Desai, D., Sinha, I., Null, K., Wolter, W., Suckow, M. A., King, T., Amin, S. & Sinha, R., Jul 1 2010, In : International Journal of Cancer. 127, 1, p. 230-238 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
2009

α-Keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells

Lee, J. I., Nian, H., Cooper, A. J. L., Sinha, R., Dai, J., Bisson, W. H., Dashwood, R. H. & Pinto, J. T., Jul 1 2009, In : Cancer Prevention Research. 2, 7, p. 683-693 11 p.

Research output: Contribution to journalArticle

55 Scopus citations
2008

Effects of naturally occurring and synthetic organoselenium compounds on protein profiling in androgen responsive and androgen independent human prostate cancer cells

Sinha, R., Pinto, J. T., Facompre, N., Kilheffer, J., Baatz, J. E. & El-Bayoumy, K., Mar 1 2008, In : Nutrition and cancer. 60, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

In vitro growth inhibition of mouse mammary epithelial tumor cells by methylseleninic acid: Involvement of protein kinases

Singh, U., Null, K. & Sinha, R., Nov 1 2008, In : Molecular Nutrition and Food Research. 52, 11, p. 1281-1288 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2007
36 Scopus citations
2006

Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds

El-Bayoumy, K., Sinha, R., Pinto, J. T. & Rivlin, R. S., Mar 1 2006, In : Journal of Nutrition. 136, 3, p. 864S-869S

Research output: Contribution to journalArticle

99 Scopus citations

Molecular targets of the chemopreventive agent 1,4-phenylenebis (methylene)-selenocyanate in human non-small cell lung cancer

El-Bayoumy, K., Das, A., Narayanan, B., Narayanan, N., Fiala, E. S., Desai, D., Rao, C. V., Amin, S. & Sinha, R., Jul 1 2006, In : Carcinogenesis. 27, 7, p. 1369-1376 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
2005

Molecular chemoprevention by selenium: A genomic approach

El-Bayoumy, K. & Sinha, R., Dec 11 2005, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 591, 1-2, p. 224-236 13 p.

Research output: Contribution to journalArticle

109 Scopus citations

Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro

Unni, E., Koul, D., Yung, W. K. A. & Sinha, R., Jul 6 2005, In : Breast Cancer Research. 7, 5, R699.

Research output: Contribution to journalArticle

50 Scopus citations
2004

Osteopontin is a potential target gene in mouse mammary cancer chemoprevention by Se-methylselenocysteine

Unni, E., Kittrell, F. S., Singh, U. & Sinha, R., Jul 29 2004, In : Breast Cancer Research. 6, 5, R586.

Research output: Contribution to journalArticle

30 Scopus citations
2003
14 Scopus citations
2001

Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth

Said, T. K., Moraes, R. C. B., Sinha, R. & Medina, D., Apr 17 2001, In : Breast Cancer Research. 3, 2, p. 122-133 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Methylseleninic acid, a potent growth inhibitor of synchronized mouse mammary epithelial tumor cells in vitro

Sinha, R., Unni, E., Ganther, H. E. & Medina, D., Feb 1 2001, In : Biochemical Pharmacology. 61, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

Se-methylselenocysteine activates caspase-3 in mouse mammary epithelial tumor cells in vitro

Unni, E., Singh, U., Ganther, H. E. & Sinha, R., Jan 1 2001, In : BioFactors. 14, 1-4, p. 169-177 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
1999

Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells

Sinha, R., Kiley, S. C., Lu, J. X., Thompson, H. J., Moraes, R., Jaken, S. & Medina, D., Nov 15 1999, In : Cancer Letters. 146, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

77 Scopus citations
1998

High incidence of IgG antibodies to phenolic glycolipid in non-leprosy patients in India

Kumar, B., Sinha, R. & Sehgal, S., Apr 1998, In : Journal of Dermatology. 25, 4, p. 238-241 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
1997

Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells

Sinha, R. & Medina, D., Aug 1 1997, In : Carcinogenesis. 18, 8, p. 1541-1547 7 p.

Research output: Contribution to journalArticle

85 Scopus citations
1996

Isolation and identification of selenium-labeled proteins in the mouse kidney

Jamba, L., Nehru, B., Medina, D., Bansal, M. P. & Sinha, R., Jul 1 1996, In : Anticancer Research. 16, 4 A, p. 1651-1657 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways

Sinha, R., Said, T. K. & Medina, D., Oct 22 1996, In : Cancer Letters. 107, 2, p. 277-284 8 p.

Research output: Contribution to journalArticle

80 Scopus citations
1994

Comparative evaluation of serological tests in Indian kala-azar

Sinha, R. & Sehgal, S., Jan 1 1994, In : Journal of Tropical Medicine and Hygiene. 97, 6, p. 333-340 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
1993

Importance of bone marrow culture for diagnosis of kala azar

Sinha, R., Datta, U. & Sehgal, S., Jan 1 1993, In : Scandinavian Journal of Infectious Diseases. 25, 6, p. 787-789 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Significance of selenium-labeled proteins for selenium's chemopreventive functions

Sinha, R., Bansal, M. P., Ganther, H. & Medina, D., Sep 1 1993, In : Carcinogenesis. 14, 9, p. 1895-1900 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
1992

Detection of Leishmania Antigen in Kala Azar Patients Using Monoclonal Antibodies

Sinha, R., Arora, S. K., Datta, U. & Sehgal, S., Apr 1992, In : Microbiology and Immunology. 36, 4, p. 391-400 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Humoral antibody response in Leishmania tropica infection

Sehgal, S., Sinha, R., Mallick, A., Arora, S. K. & Hazra, P. K., Jan 1 1992, In : Journal of Infection. 24, 3

Research output: Contribution to journalArticle

5 Scopus citations
1991

Use of in vitro method to assess different brands of anti-leishmanial drugs

Arora, S. K., Sinha, R. & Sehgal, S., Mar 1 1991, In : Medical Microbiology and Immunology. 180, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
1989

Use of whole parasite for quick screening of hybridomas against Leishmania donovani

Sinha, R., Arora, S. K. & Sehgal, S., Jan 1 1989, In : Hybridoma. 8, 2, p. 259-261 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
1988

A sensitive ELISA for detection of circulating antigens in kala azar patients.

Sinha, R., Arora, S. K. & Sehgal, S., Aug 1 1988, In : The Indian journal of medical research. 88, p. 138-140 3 p.

Research output: Contribution to journalArticle

4 Scopus citations