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Research Output 1992 2019

2019
1 Citation (Scopus)

Association between testosterone, semen parameters, and live birth in men with unexplained infertility in an intrauterine insemination population

Reproductive Medicine Network, Jun 1 2019, In : Fertility and sterility. 111, 6, p. 1129-1134 6 p.

Research output: Contribution to journalArticle

Insemination
Live Birth
Semen
Infertility
Testosterone
2 Citations (Scopus)

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome

Brower, M. A., Hai, Y., Jones, M. R., Guo, X., Chen, Y. D. I., Rotter, J. I., Krauss, R. M., Legro, R., Azziz, R. & Goodarzi, M. O., Jan 1 2019, In : Human Reproduction. 34, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Random Allocation
Body Mass Index
Single Nucleotide Polymorphism
Mendelian Randomization Analysis

Distinctive Reproductive Phenotypes in Peripubertal Girls at Risk for Polycystic Ovary Syndrome

Torchen, L. C., Legro, R. & Dunaif, A., Jun 19 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3355-3361 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Hormones
Phenotype
Weights and Measures
Sex Hormone-Binding Globulin

Fertility Related Quality of Life, Gonadal Function and Erectile Dysfunction in Male Partners of Couples with Unexplained Infertility

Coward, R. M., Stetter, C., Kunselman, A., Trussell, J. C., Lindgren, M. C., Alvero, R. R., Casson, P., Christman, G. M., Coutifaris, C., Diamond, M. P., Hansen, K. R., Krawetz, S. A., Legro, R., Robinson, R. D., Smith, J. F., Steiner, A. Z., Wild, R. A., Zhang, H. & Santoro, N., Aug 1 2019, In : Journal of Urology. 202, 2, p. 379-384 6 p.

Research output: Contribution to journalArticle

Erectile Dysfunction
Infertility
Fertility
Testosterone
Quality of Life
8 Citations (Scopus)

Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial

Wei, D., Liu, J. Y., Sun, Y., Shi, Y., Zhang, B., Liu, J. Q., Tan, J., Liang, X., Cao, Y., Wang, Z., Qin, Y., Zhao, H., Zhou, Y., Ren, H., Hao, G., Ling, X., Zhao, J., Zhang, Y., Qi, X., Zhang, L. & 10 others, Deng, X., Chen, X., Zhu, Y., Wang, X., Tian, L. F., Lv, Q., Ma, X., Zhang, H., Legro, R. & Chen, Z. J., Mar 30 2019, In : The Lancet. 393, 10178, p. 1310-1318 9 p.

Research output: Contribution to journalArticle

Embryo Transfer
Randomized Controlled Trials
Single Embryo Transfer
Embryonic Structures
Pregnancy Rate
1 Citation (Scopus)

Functional Genetic Variation in the Anti-Müllerian Hormone Pathway in Women With Polycystic Ovary Syndrome

Gorsic, L. K., Dapas, M., Legro, R., Hayes, M. G. & Urbanek, M., Jul 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2855-2874 20 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Hormones
Assays
Nucleic Acid Regulatory Sequences
Hyperandrogenism
Assisted Reproductive Techniques
Mitochondria
Mitochondrial DNA
Embryonic Structures
Mitochondrial Dynamics

Lower prevalence of non–cavity-distorting uterine fibroids in patients with polycystic ovary syndrome than in those with unexplained infertility

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, May 1 2019, In : Fertility and sterility. 111, 5, p. 1011-1019.e1

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Leiomyoma
Infertility
Body Mass Index
Live Birth

Pharmacology of medications used for ovarian stimulation

Quaas, A. M. & Legro, R., Feb 1 2019, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 33, 1, p. 21-33 13 p.

Research output: Contribution to journalReview article

letrozole
Ovulation Induction
Ovary
Kisspeptins
Pharmacology

Reprint of: Histological dating of timed endometrial biopsy tissue is not related to fertility status

NICHD National Cooperative Reproductive Medicine Network, Oct 1 2019, In : Fertility and sterility. 112, 4, p. e116-e124

Research output: Contribution to journalArticle

2 Citations (Scopus)

The efficiency of single institutional review board review in National Institute of Child Health and Human Development Cooperative Reproductive Medicine Network–initiated clinical trials

for the National Institute of Child Health and Human Development Cooperative Reproductive Medicine Network, Feb 1 2019, In : Clinical Trials. 16, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

National Institute of Child Health and Human Development (U.S.)
Reproductive Medicine
Research Ethics Committees
Clinical Trials
Language
2018
2 Citations (Scopus)

Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility

Barrett, E. S., Vitek, W., Mbowe, O., Thurston, S. W., Legro, R., Alvero, R., Baker, V., Wright Bates, G., Casson, P., Coutifaris, C., Eisenberg, E., Hansen, K., Krawetz, S., Robinson, R., Rosen, M., Usadi, R., Zhang, H., Santoro, N. & Diamond, M., Jan 1 2018, In : Human Reproduction. 33, 9, p. 1757-1766 10 p.

Research output: Contribution to journalArticle

Allostasis
Physiological Stress
Pregnancy Outcome
Infertility
Fertility
2 Citations (Scopus)

Association among depression, symptom experience, and quality of life in polycystic ovary syndrome

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Sep 1 2018, In : American journal of obstetrics and gynecology. 219, 3, p. 279.e1-279.e7

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Quality of Life
Depression
Infertility
Hirsutism

Association among Depression, Symptom Experience, and Quality of Life in Polycystic Ovary Syndrome

Greenwood, E. A., Pasch, L. A., Cedars, M. I., Legro, R. & Huddleston, H. G., Dec 1 2018, In : Obstetrical and Gynecological Survey. 73, 12, p. 691-692 2 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Quality of Life
2 Citations (Scopus)

A Vision for Improving the Assessment and Management of PCOS through International Collaboration

Teede, H. J., Legro, R. & Norman, R. J., Jan 1 2018, In : Seminars in Reproductive Medicine. 36, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

Comparison of sonohysterography to hysterosalpingogram for tubal patency assessment in a multicenter fertility treatment trial among women with polycystic ovary syndrome

Christianson, M. S., Legro, R., Jin, S., Eisenberg, E., Diamond, M. P., Hansen, K. R., Vitek, W., Styer, A. K., Casson, P., Coutifaris, C., Christman, G. M., Alvero, R., Puscheck, E. E., Christy, A. Y., Sun, F., Zhang, H., Polotsky, A. J. & Santoro, N., Jan 1 2018, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Fertility
letrozole
Pregnancy
Therapeutics

Data Do Not Support Effectiveness of Acupuncture for Improving Live Birth Rate in Women with Polycystic Ovary Syndrome

Kuang, H. Y., Li, Y., Zhang, H. P., Legro, R. & Stener-Victorin, E., May 1 2018, In : Chinese Journal of Integrative Medicine. 24, 5, p. 399-400 2 p.

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
Birth Rate
Live Birth
Acupuncture

Data sharing requirements: perspectives from three authors

Barnhart, K. T., Legro, R. & Scott, R. T., Jan 1 2018, In : Fertility and Sterility. 109, 1, p. 44-47 4 p.

Research output: Contribution to journalEditorial

Information Dissemination
1 Citation (Scopus)

Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction

Li, J., Wu, Q., Wu, X. K., Zhou, Z. M., Fu, P., Chen, X. H., Yan, Y., Wang, X., Yang, Z. W., Li, W. L., Stener-Victorin, E., Legro, R., Ng, E. H. Y., Zhang, H., Mol, B. W. J. & Wang, C. C., Apr 1 2018, In : Human Reproduction. 33, 4, p. 617-625 9 p.

Research output: Contribution to journalArticle

Hyperandrogenism
Tobacco Smoke Pollution
Ovulation Induction
Polycystic Ovary Syndrome
Spouses

Effect of Preconception Impaired Glucose Tolerance on Pregnancy Outcomes in Women with Polycystic Ovary Syndrome

Wei, D., Zhang, B., Shi, Y., Zhang, L., Zhao, S., Du, Y., Xu, L., Legro, R., Zhang, H. & Chen, Z. J., Mar 1 2018, In : Obstetrical and Gynecological Survey. 73, 3, p. 158-159 2 p.

Research output: Contribution to journalComment/debate

Glucose Intolerance
Polycystic Ovary Syndrome
Pregnancy Outcome

Gerald JHarkins, MD, MPT, FACOG

Legro, R., Jan 1 2018, In : Seminars in Reproductive Medicine. 36, 2, 1 p.

Research output: Contribution to journalEditorial

Gestational weight gain in women with polycystic ovary syndrome: A controlled study

Kent, J., Dodson, W., Kunselman, A., Pauli, J., Stone, A., Diamond, M. P., Coutifaris, C., Schlaff, W. D., Alvero, R., Casson, P., Christman, G. M., Rosen, R. M., Hansen, K. R., Robinson, R. D., Baker, V., Usadi, R., Santoro, N., Zhang, H., Eisenberg, E. & Legro, R., Jan 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 11, p. 4315-4323 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Weight Gain
Weights and Measures
Body Mass Index
Pregnancy Complications
3 Citations (Scopus)

Insulin resistance is associated with depression risk in polycystic ovary syndrome

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Jul 1 2018, In : Fertility and sterility. 110, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Depression
letrozole
Confidence Intervals
7 Citations (Scopus)

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

the 23andMe Research Team, Dec 1 2018, In : PLoS genetics. 14, 12, e1007813.

Research output: Contribution to journalArticle

Open Access
polycystic ovary syndrome
Polycystic Ovary Syndrome
meta-analysis
Meta-Analysis
genome
Polycystic Ovary Syndrome
Weight Loss
Pregnancy
exenatide
4 Citations (Scopus)

Major depression, antidepressant use, and male and female fertility

Reproductive Medicine Network, May 1 2018, In : Fertility and sterility. 109, 5, p. 879-887 9 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Fertility
Depression
letrozole
Spontaneous Abortion
1 Citation (Scopus)

Midluteal progesterone: A marker of treatment outcomes in couples with unexplained infertility

Hansen, K. R., Eisenberg, E., Baker, V., Hill, M. J., Chen, S., Talken, S., Diamond, M. P., Legro, R., Coutifaris, C., Alvero, R., Robinson, R. D., Casson, P., Christman, G. M., Santoro, N., Zhang, H. & Wild, R. A., Jul 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2743-2751 9 p.

Research output: Contribution to journalArticle

Ovulation Induction
Infertility
Progesterone
Insemination
Live Birth
13 Citations (Scopus)

Obstetric complications after frozen versus fresh embryo transfer in women with polycystic ovary syndrome: results from a randomized trial

Zhang, B., Wei, D., Legro, R., Shi, Y., Li, J., Zhang, L., Hong, Y., Sun, G., Zhang, T., Li, W. & Chen, Z. J., Feb 1 2018, In : Fertility and sterility. 109, 2, p. 324-329 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Embryo Transfer
Obstetrics
Gestational Age
Twin Pregnancy
31 Citations (Scopus)

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome

the International PCOS Network, Sep 1 2018, In : Clinical Endocrinology. 89, 3, p. 251-268 18 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Guidelines
Endocrinology
Consensus
Consumer Organizations
54 Citations (Scopus)

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome

International PCOS Network, Aug 1 2018, In : Fertility and sterility. 110, 3, p. 364-379 16 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Guidelines
Health
Consumer Organizations
Biomedical Research
62 Citations (Scopus)

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome

on behalf of the International PCOS Network, Jan 1 2018, In : Human Reproduction. 33, 9, p. 1602-1618 17 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Guidelines
Health
Consumer Organizations
Biomedical Research
2 Citations (Scopus)

The effect of supraphysiological estradiol on pregnancy outcomes differs between women with PCOS and ovulatory women

Wei, D., Yu, Y., Sun, M., Shi, Y., Sun, Y., Deng, X., Li, J., Wang, Z., Zhao, S., Zhang, H., Legro, R. & Chen, Z. J., Jul 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2735-2742 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Embryo Transfer
Pregnancy Outcome
Estradiol
Live Birth

The International Guideline in Polycystic Ovary Syndrome

Legro, R., Jan 1 2018, In : Seminars in Reproductive Medicine. 36, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Polycystic Ovary Syndrome
Guidelines
59 Citations (Scopus)

Transfer of fresh versus frozen embryos in ovulatory women

Shi, Y., Sun, Y., Hao, C., Zhang, H., Wei, D., Zhang, Y., Zhu, Y., Deng, X., Qi, X., Li, H., Ma, X., Ren, H., Wang, Y., Zhang, D., Wang, B., Liu, F., Wu, Q., Wang, Z., Bai, H., Li, Y. & 10 others, Zhou, Y., Sun, M., Liu, H., Li, J., Zhang, L., Chen, X., Zhang, S., Sun, X., Legro, R. & Chen, Z. J., Jan 11 2018, In : New England Journal of Medicine. 378, 2, p. 126-136 11 p.

Research output: Contribution to journalArticle

Embryo Transfer
Embryonic Structures
Live Birth
Birth Rate
Ovarian Hyperstimulation Syndrome

Transfer of fresh versus frozen embryos in ovulatory women

Shi, Y., Sun, Y., Hao, C., Zhang, H., Wei, D., Zhang, Y., Zhu, Y., Deng, X., Qi, X., Li, H., Ma, X., Ren, H., Wang, Y., Zhang, D., Wang, B., Liu, F., Wu, Q., Wang, Z., Bai, H., Li, Y. & 10 others, Zhou, Y., Sun, M., Liu, H., Li, J., Zhang, L., Chen, X., Zhang, S., Sun, X., Legro, R. & Chen, Z. J., Apr 1 2018, In : Obstetrical and Gynecological Survey. 73, 4, p. 213-214 2 p.

Research output: Contribution to journalComment/debate

Embryonic Structures
2 Citations (Scopus)

Vitamin D Deficiency Is Associated with Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility

Butts, S. F., Seifer, D. B., Koelper, N., Senapati, S., Sammel, M. D., Hoofnagle, A. N., Kelly, A., Krawetz, S. A., Santoro, N., Zhang, H., Diamond, M. P. & Legro, R., Nov 9 2018, In : Journal of Clinical Endocrinology and Metabolism. 104, 2, p. 369-378 10 p.

Research output: Contribution to journalArticle

Vitamin D Deficiency
Ovulation Induction
Polycystic Ovary Syndrome
Vitamin D
Infertility
2017
7 Citations (Scopus)

Age-stratified thresholds of anti-Müllerian hormone improve prediction of polycystic ovary syndrome over a population-based threshold

the NIH/NICHD Reproductive Medicine Network, Dec 1 2017, In : Clinical Endocrinology. 87, 6, p. 733-740 8 p.

Research output: Contribution to journalArticle

Anti-Mullerian Hormone
Polycystic Ovary Syndrome
Hormones
Population
Biomarkers
9 Citations (Scopus)

Association of uterine fibroids and pregnancy outcomes after ovarian stimulation–intrauterine insemination for unexplained infertility

National Institute of Child Health and Human Development Reproductive Medicine Network, Mar 1 2017, In : Fertility and sterility. 107, 3, p. 756-762.e3

Research output: Contribution to journalArticle

Insemination
Leiomyoma
Pregnancy Outcome
Infertility
Birth Rate
41 Citations (Scopus)

Effect of acupuncture and clomiphene in Chinese women with polycystic ovary syndrome: A randomized clinical trial

PCOSAct Study Group, Jun 27 2017, In : JAMA - Journal of the American Medical Association. 317, 24, p. 2502-2514 13 p.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Acupuncture
Randomized Controlled Trials
Live Birth
2 Citations (Scopus)

Effect of preconception impaired glucose tolerance on pregnancy outcomes in women with polycystic ovary syndrome

Wei, D., Zhang, B., Shi, Y., Zhang, L., Zhao, S., Du, Y., Xu, L., Legro, R., Zhang, H. & Chen, Z. J., Oct 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 10, p. 3822-3829 8 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Polycystic Ovary Syndrome
Pregnancy Outcome
Glucose
Odds Ratio
12 Citations (Scopus)

Effect of pretreatment with oral contraceptives and progestins on IVF outcomes in women with polycystic ovary syndrome

Wei, D., Shi, Y., Li, J., Wang, Z., Zhang, L., Sun, Y., Zhou, H., Xu, Y., Wu, C., Liu, L., Wu, Q., Zhuang, L., Du, Y., Li, W., Zhang, H., Legro, R. & Chen, Z. J., Jan 1 2017, In : Human Reproduction. 32, 2, p. 354-361 8 p.

Research output: Contribution to journalArticle

Menstruation
Polycystic Ovary Syndrome
Progestins
Oral Contraceptives
Embryo Transfer
9 Citations (Scopus)

Effects of obesity treatment on female reproduction: results do not match expectations

Legro, R., Apr 1 2017, In : Fertility and sterility. 107, 4, p. 860-867 8 p.

Research output: Contribution to journalReview article

Weight Gain
Reproduction
Weight Loss
Bariatric Surgery
Obesity

Hot Topics Issue

Legro, R., Jul 1 2017, In : Seminars in Reproductive Medicine. 35, 4, 1 p.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

Impact of hormonal contraception and weight loss on high-density lipoprotein cholesterol efflux and lipoprotein particles in women with polycystic ovary syndrome

Dokras, A., Playford, M., Kris-Etherton, P. M., Kunselman, A., Stetter, C. M., Williams, N., Gnatuk, C., Estes, S., Sarwer, D. B., Allison, K. C., Coutifaris, C., Mehta, N. & Legro, R., May 1 2017, In : Clinical Endocrinology. 86, 5, p. 739-746 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Oral Contraceptives
Contraception
HDL Cholesterol
Lipoproteins

Iris LRomero, MD, MS

Legro, R., Sep 1 2017, In : Seminars in Reproductive Medicine. 35, 5, 1 p.

Research output: Contribution to journalEditorial

Iris

James HSegars, MD and Ayman Al-Hendy, MD, PhD

Legro, R., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 469-470 2 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Mindfulness-Based Stress Reduction in Women with Overweight or Obesity: A Randomized Clinical Trial

Raja-Khan, N., Agito, K., Shah, J., Stetter, C. M., Gustafson, T. S., Socolow, H., Kunselman, A., Reibel, D. K. & Legro, R., Aug 1 2017, In : Obesity. 25, 8, p. 1349-1359 11 p.

Research output: Contribution to journalArticle

Mindfulness
Randomized Controlled Trials
Obesity
Health Education
Glucose
6 Citations (Scopus)

Normal pubertal development in daughters of women with PCOS: A controlled study

Legro, R., Kunselman, A., Stetter, C. M., Gnatuk, C., Estes, S., Brindle, E., Vesper, H. W., Botelho, J. C., Lee, P. & Dodson, W., Jan 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Nuclear Family
Gonadotropins
Insulin
Steroids
14 Citations (Scopus)

Pathogenic anti-Müllerian hormone variants in polycystic ovary syndrome

Gorsic, L. K., Kosova, G., Werstein, B., Sisk, R., Legro, R., Hayes, M. G., Teixeira, J. M., Dunaif, A. & Urbanek, M., Aug 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 8, p. 2862-2872 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Hormones
Steroid 17-alpha-Hydroxylase
Biosynthesis
Androgens

Pharmacologic Treatment of Polycystic Ovary Syndrome: Alternate and Future Paths

Duguech, L. M. M. & Legro, R., Jul 1 2017, In : Seminars in Reproductive Medicine. 35, 4, p. 326-343 18 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Therapeutics
Drug Repositioning
Anovulation
Secretory Pathway