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Research Output 1992 2019

20 Citations (Scopus)

A 27-year-old woman with a diagnosis of polycystic ovary syndrome

Legro, R., Feb 7 2007, In : Journal of the American Medical Association. 297, 5, p. 509-519 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Menstruation
Weight Gain
Hirsutism
Expert Testimony

A brief update on the evidence supporting the treatment of infertility in polycystic ovary syndrome

Costello, M. F., Misso, M. L., Balen, A., Boyle, J., Devoto, L., Garad, R. M., Hart, R., Johnson, L., Jordan, C., Legro, R. S., Norman, R. J., Moran, L., Mocanu, E., Qiao, J., Rodgers, R. J., Rombauts, L., Tassone, E. C., Thangaratinam, S., Vanky, E. & Teede, H. J., Jan 1 2019, (Accepted/In press) In : Australian and New Zealand Journal of Obstetrics and Gynaecology.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
letrozole
Ovulation Induction
Clomiphene
34 Citations (Scopus)

Absence of secretory endometrium after false-positive home urine luteinizing hormone testing

McGovern, P. G., Myers, E. R., Silva, S., Coutifaris, C., Carson, S. A., Legro, R., Schlaff, W. D., Carr, B. R., Steinkampf, M. P., Giudice, L. C., Leppert, P. C. & Diamond, M. P., Jan 1 2004, In : Fertility and sterility. 82, 5, p. 1273-1277 5 p.

Research output: Contribution to journalArticle

Luteinizing Hormone
Endometrium
Urine
Biopsy
Luteal Phase
9 Citations (Scopus)
Reproduction
Clinical Trials
African Americans
Volunteers
Research
24 Citations (Scopus)

Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: Study design of a randomized controlled trial

Kuang, H., Li, Y., Wu, X., Hou, L., Wu, T., Liu, J., Ng, E. H. Y., Stener-Victorin, E., Legro, R. S. & Zhang, H., Sep 23 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 527303.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Live Birth
Acupuncture
Randomized Controlled Trials
13 Citations (Scopus)

Adolescent Caucasian mothers have reduced adult hip bone density

Lloyd, T., Lin, H. M., Eggli, D. F., Dodson, W. C., Demers, L. M. & Legro, R. S., Feb 5 2002, In : Fertility and sterility. 77, 1, p. 136-140 5 p.

Research output: Contribution to journalArticle

Pelvic Bones
Bone Density
Mothers
Pregnancy in Adolescence
Menarche
305 Citations (Scopus)
Polycystic Ovary Syndrome
Androgens
Insulin Resistance
Obesity
Insulin
26 Citations (Scopus)

A dopamine D3 receptor genotype is associated with hyperandrogenic chronic anovulation and resistant to ovulation induction with clomiphene citrate in female hispanics

Legro, R., Muhleman, D. R., Comings, D. E., Lobo, R. A. & Kovacs, B. W., Jan 1 1995, In : Fertility and sterility. 63, 4, p. 779-784 6 p.

Research output: Contribution to journalArticle

Dopamine D3 Receptors
Anovulation
Clomiphene
Ovulation Induction
Hispanic Americans
622 Citations (Scopus)

A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome

Legro, R., Finegood, D. & Dunaif, A., Nov 10 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 8, p. 2694-2698 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Fasting
Insulin
Glucose
7 Citations (Scopus)

Age-stratified thresholds of anti-Müllerian hormone improve prediction of polycystic ovary syndrome over a population-based threshold

the NIH/NICHD Reproductive Medicine Network, Dec 1 2017, In : Clinical Endocrinology. 87, 6, p. 733-740 8 p.

Research output: Contribution to journalArticle

Anti-Mullerian Hormone
Polycystic Ovary Syndrome
Hormones
Population
Biomarkers
5 Citations (Scopus)

A good meta-analysis is hard to find

Legro, R. & Kunselman, A., Jan 1 2012, In : Fertility and sterility. 97, 5, p. 1048-1049 2 p.

Research output: Contribution to journalEditorial

Female Fertility Agents
Female Infertility
Assisted Reproductive Techniques
Ovulation Induction
Luteinizing Hormone
79 Citations (Scopus)

Allelic variants of the follistatin gene in polycystic ovary syndrome

Urbanek, M., Wu, X., Vickery, K. R., Kao, L. C., Christenson, L. K., Schneyer, A., Legro, R., Driscoll, D. A., Strauss, J. F., Dunaif, A. & Spielman, R. S., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 12, p. 4455-4461 7 p.

Research output: Contribution to journalArticle

Follistatin
Polycystic Ovary Syndrome
Genes
Genetic Linkage
Fibroblasts
2 Citations (Scopus)

Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility

Barrett, E. S., Vitek, W., Mbowe, O., Thurston, S. W., Legro, R. S., Alvero, R., Baker, V., Wright Bates, G., Casson, P., Coutifaris, C., Eisenberg, E., Hansen, K., Krawetz, S., Robinson, R., Rosen, M., Usadi, R., Zhang, H., Santoro, N. & Diamond, M., Jan 1 2018, In : Human Reproduction. 33, 9, p. 1757-1766 10 p.

Research output: Contribution to journalArticle

Allostasis
Physiological Stress
Pregnancy Outcome
Infertility
Fertility

Alterations in androgen conjugate levels in women and men with alopecia

Legro, R., Carmina, E., Stanczyk, FZ. Z., Gentzschein, E. & Lobo, RA. A., Dec 1 1995, In : ACOG Current Journal Review. 8, 2, p. 23-24 2 p.

Research output: Contribution to journalEditorial

20 Citations (Scopus)

Alterations in androgen conjugate levels in women and men with alopecia

Legro, R., Carmina, E., Stanczyk, F. Z., Gentzschein, E. & Lobo, R. A., Jan 1 1994, In : Fertility and sterility. 62, 4, p. 744-750 7 p.

Research output: Contribution to journalArticle

Alopecia
Androgens
Glucuronides
Sulfates
Hirsutism
51 Citations (Scopus)
Polycystic Ovary Syndrome
HDL Lipoproteins
LDL Lipoproteins
Hispanic Americans
Insulin
102 Citations (Scopus)

Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome

Nelson-Degrave, V. L., Wickenheisser, J. K., Hendricks, K. L., Asano, T., Fujishiro, M., Legro, R., Kimball, S., Strauss, J. F. & McAllister, J., Feb 1 2005, In : Molecular Endocrinology. 19, 2, p. 379-390 12 p.

Research output: Contribution to journalArticle

Theca Cells
Polycystic Ovary Syndrome
Mitogen-Activated Protein Kinase Kinases
Steroid 17-alpha-Hydroxylase
Androgens
6 Citations (Scopus)

Altering hirsutism through ovulation induction in women with polycystic ovary syndrome

Roth, L. W., Huang, H., Legro, R., Diamond, M. P., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R., Zhang, H. & Schlaff, W. D., Jun 1 2012, In : Obstetrics and Gynecology. 119, 6, p. 1151-1156 6 p.

Research output: Contribution to journalArticle

Hirsutism
Ovulation Induction
Polycystic Ovary Syndrome
Clomiphene
Metformin
112 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Insulin Resistance
127 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Anovulation
2 Citations (Scopus)

A multi-center randomized trial of two different intravenous fluids during labor

Dapuzzo-Argiriou, L. M., Smulian, J. C., Rochon, M. L., Galdi, L., Kissling, J. M., Schnatz, P. F., Gonzalez Rios, A., Airoldi, J., Carrillo, M. A., Maines, J., Kunselman, A., Repke, J. & Legro, R., Jan 17 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

Glucose
Dilatation
Birth Rate
Internship and Residency
Obstetrics

Androgen excess disorders

Legro, R. & Azziz, R., Mar 27 2012, Danforth's Obstetrics and Gynecology: Tenth Edition. Wolters Kluwer Health Adis (ESP), p. 682-704 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Androgens
17 Citations (Scopus)

Angiotensin-converting enzyme inhibition reverses luteal phase steroid production in oocyte donors

Morris, R. S., Paulson, R. J., Lindhelm, S. R., Legro, R., Lobo, R. A. & Sauer, M. V., Jan 1 1995, In : Fertility and sterility. 63, 4, p. 854-858 5 p.

Research output: Contribution to journalArticle

Luteal Phase
Peptidyl-Dipeptidase A
Angiotensin II
Oocytes
Steroids
2 Citations (Scopus)

A patient's guide: polycystic ovary syndrome (PCOS).

Hoeger, K. M., Legro, R. S. & Welt, C. K., Jan 2014, In : Unknown Journal. 99, 1, p. 35A-36A

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Young Adult
Differential Diagnosis
Endocrine Diagnostic Techniques
31 Citations (Scopus)

A randomized comparison of the methods of sperm preparation for intrauterine insemination

Dodson, W., Moessner, J., Miller, J., Legro, R. & Gnatuk, C., Oct 5 1998, In : Fertility and sterility. 70, 3, p. 574-575 2 p.

Research output: Contribution to journalArticle

Insemination
Spermatozoa
Superovulation
Fertility
Centrifugation
156 Citations (Scopus)

A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome

Stamets, K., Taylor, D. S., Kunselman, A., Demers, L., Pelkman, C. L. & Legro, R., Mar 1 2004, In : Fertility and Sterility. 81, 3, p. 630-637 8 p.

Research output: Contribution to journalArticle

Reducing Diet
Polycystic Ovary Syndrome
Diet
Weight Loss
Fats
21 Citations (Scopus)

ART in women 40 and over: Is the cost worth it?

Legro, R. S., Shackleford, D. P., Moessner, J. M., Gnatuk, C. L. & Dodson, W. C., Feb 1 1997, In : Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 42, 2, p. 76-82 7 p.

Research output: Contribution to journalArticle

Costs and Cost Analysis
Pregnancy
Assisted Reproductive Techniques
Infertility
Oocytes
19 Citations (Scopus)

Assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: Baseline characteristics

Diamond, M. P., Legro, R. S., Coutifaris, C., Alvero, R., Robinson, R. D., Casson, P., Christman, G. M., Ager, J., Huang, H., Hansen, K. R., Baker, V., Usadi, R., Seungdamrong, A., Bates, G. W., Rosen, R. M., Haisonleder, D., Krawetz, S. A., Barnhart, K., Trussell, J. C., Jin, Y. & 74 others, Santoro, N., Eisenberg, E., Zhang, H., Bartlebaugh, C., Dodson, W., Estes, S., Gnatuk, C., Ladda, R., Ober, J., Easton, C., Hernandez, A., Leija, M., Pierce, D., Brzyski, R., Awonuga, A., Cedo, L., Cline, A., Collins, K., Puscheck, E., Singh, M., Yoscovits, M., Lecks, K., Martino, L., Marunich, R., Comfort, A., Crow, M., Hohmann, A., Mallette, S., Smith, Y., Randolph, J., Fisseha, S., Ringbloom, M., Tang, J., Mason, S., Di Maria, N., Laylor, B., Martinez, L., Solnica, A., Wojtczuk, A., Rhea, M., Turner, K., Craig, L. B., Zornes, C., Rodriguez, M. R., Hunt, T. S., Remble, T., Cheng, G., Green, L., Lenhart, N., Del Basso, D., Brennan, M., Kuang, H., Li, Y., Patrizio, P., Sakai, L., Song, C., Taylor, H., Thomas, T., Yan, Q., Zhang, M., Lamar, C., De Paolo, L., Guzick, D., Herring, A., Redmond, J. B., Thomas, M., Turek, P., Wactawski-Wende, J., Rebar, R., Cato, P., Dukic, V., Lewis, V., Schlegel, P. & Witter, F., Jan 1 2015, In : Fertility and sterility. 103, 4, p. 962-973.e4

Research output: Contribution to journalArticle

Ovulation Induction
letrozole
Infertility
Pregnancy
Clomiphene
3 Citations (Scopus)

Association among depression, symptom experience, and quality of life in polycystic ovary syndrome

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Sep 1 2018, In : American journal of obstetrics and gynecology. 219, 3, p. 279.e1-279.e7

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Quality of Life
Depression
Infertility
Hirsutism

Association among Depression, Symptom Experience, and Quality of Life in Polycystic Ovary Syndrome

Greenwood, E. A., Pasch, L. A., Cedars, M. I., Legro, R. & Huddleston, H. G., Dec 1 2018, In : Obstetrical and Gynecological Survey. 73, 12, p. 691-692 2 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Quality of Life
1 Citation (Scopus)

Association between testosterone, semen parameters, and live birth in men with unexplained infertility in an intrauterine insemination population

Reproductive Medicine Network, Jun 1 2019, In : Fertility and sterility. 111, 6, p. 1129-1134 6 p.

Research output: Contribution to journalArticle

Insemination
Live Birth
Semen
Infertility
Testosterone
53 Citations (Scopus)

Association between Tourette's syndrome and homozygosity at the dopamine D3 receptor gene

Comings, D. E., Muhleman, D., Dietz, G., Dino, M., Legro, R. & Gade, R., Apr 3 1993, In : The Lancet. 341, 8849, 1 p.

Research output: Contribution to journalLetter

36 Citations (Scopus)
Superovulation
Insemination
Obesity
Thinness
Gonadotropins
9 Citations (Scopus)

Association of uterine fibroids and pregnancy outcomes after ovarian stimulation–intrauterine insemination for unexplained infertility

National Institute of Child Health and Human Development Reproductive Medicine Network, Mar 1 2017, In : Fertility and sterility. 107, 3, p. 756-762.e3

Research output: Contribution to journalArticle

Insemination
Leiomyoma
Pregnancy Outcome
Infertility
Birth Rate
40 Citations (Scopus)
Polycystic Ovary Syndrome
Gestational Age
Phenotype
Health
Population
4 Citations (Scopus)

Association study of androgen signaling pathway genes in polycystic ovary syndrome

Ketefian, A., Jones, M. R., Krauss, R. M., Chen, Y. D. I., Legro, R., Azziz, R. & Goodarzi, M. O., Feb 1 2016, In : Fertility and sterility. 105, 2, p. 467-473.e4

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Genes
Single Nucleotide Polymorphism
Androgen Receptors
8 Citations (Scopus)

A twenty-first century research agenda for polycystic ovary syndrome

Legro, R., Azziz, R. & Giudice, L., Jun 1 2006, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 20, 2, p. 331-336 6 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Research
Translational Medical Research
Expert Testimony
Natural History
344 Citations (Scopus)

Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries

Nelson, V. L., Legro, R., Strauss, J. F. & McAllister, J., Jan 1 1999, In : Molecular Endocrinology. 13, 6, p. 946-957 12 p.

Research output: Contribution to journalArticle

Theca Cells
Polycystic Ovary Syndrome
Androgens
Ovary
Phenotype
29 Citations (Scopus)

A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome

Raja-Khan, N., Kunselman, A., Demers, L., Ewens, K. G., Spielman, R. S. & Legro, R., Dec 1 2010, In : Fertility and sterility. 94, 7, p. 2916-2919 4 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Transforming Growth Factors
Alleles
Genes
Ovary
2 Citations (Scopus)

A Vision for Improving the Assessment and Management of PCOS through International Collaboration

Teede, H. J., Legro, R. & Norman, R. J., Jan 1 2018, In : Seminars in Reproductive Medicine. 36, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Barriers to conducting clinical research in reproductive medicine: United States of America

Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 4, p. 817-819 3 p.

Research output: Contribution to journalArticle

Reproductive Medicine
National Institutes of Health (U.S.)
Research
5 Citations (Scopus)

Baseline AMH level associated with ovulation following ovulation induction in women with polycystic ovary syndrome

Mumford, S. L., Legro, R. S., Diamond, M. P., Coutifaris, C., Steiner, A. Z., Schlaff, W. D., Alvero, R., Christman, G. M., Casson, P. R., Huang, H., Santoro, N., Eisenberg, E., Zhang, H. & Cedars, M. I., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3288-3296 9 p.

Research output: Contribution to journalArticle

Ovulation Induction
Polycystic Ovary Syndrome
Ovulation
Hormones
Serum
184 Citations (Scopus)

Behavioral stress responses in premenopausal and postmenopausal women and the effects of estrogen

Lindheim, S. R., Legro, R., Bernstein, L., Stanczyk, F. Z., Vijod, M. A., Presser, S. C. & Lobo, R. A., Jan 1 1992, In : American Journal of Obstetrics and Gynecology. 167, 6, p. 1831-1836 6 p.

Research output: Contribution to journalArticle

Estrogens
Exercise Test
Placebos
Blood Pressure
Psychological Stress
33 Citations (Scopus)

Benefit of delayed fertility therapy with preconception weight loss over immediate therapy in obese women with PCOS

Legro, R. S., Dodson, W. C., Kunselman, A. R., Stetter, C. M., Kris-Etherton, P. M., Williams, N. I., Gnatuk, C. L., Estes, S. J., Allison, K. C., Sarwer, D. B., Diamond, M. P., Schlaff, W. D., Casson, P. R., Christman, G. M., Barnhart, K. T., Wright Bates, G., Usadi, R., Lucidi, S., Baker, V., Zhang, H. & 3 others, Eisenberg, E., Coutifaris, C. & Dokras, A., Jul 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 7, p. 2658-2666 9 p.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Fertility
Weight Loss
Oral Contraceptives
2 Citations (Scopus)

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome

Brower, M. A., Hai, Y., Jones, M. R., Guo, X., Chen, Y. D. I., Rotter, J. I., Krauss, R. M., Legro, R., Azziz, R. & Goodarzi, M. O., Jan 1 2019, In : Human Reproduction. 34, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Random Allocation
Body Mass Index
Single Nucleotide Polymorphism
Mendelian Randomization Analysis
6 Citations (Scopus)

Body mass index and intercourse compliance

Pagidas, K., Carson, S. A., McGovern, P. G., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Steinkampf, M. P., Cataldo, N. A., Nestler, J. E., Gosman, G. & Giudice, L. C., Sep 1 2010, In : Fertility and sterility. 94, 4, p. 1447-1450 4 p.

Research output: Contribution to journalArticle

Compliance
Body Mass Index
Polycystic Ovary Syndrome
Reproductive Medicine
Pregnancy
65 Citations (Scopus)

Bone mineral density and body composition in lean women with polycystic ovary syndrome

Good, C., Tulchinsky, M., Mauger, D., Demers, L. & Legro, R., Jul 1 1999, In : Fertility and Sterility. 72, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Body Composition
Bone Density
Fats
Androgens
8 Citations (Scopus)
Brachial Artery
Polycystic Ovary Syndrome
Hyperemia
LDL Cholesterol
Fasting
52 Citations (Scopus)

Brief Report: Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome

Hickey, T. E., Legro, R. & Norman, R. J., Jul 14 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 7, p. 2789-2791 3 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
X Chromosome Inactivation
X Chromosome
Chromosomes
Epigenomics
109 Citations (Scopus)

Candidate gene region for polycystic ovary syndrome on chromosome 19p13.2

Urbanek, M., Woodroffe, A., Ewens, K. G., Diamanti-Kandarakis, E., Legro, R., Strauss, J. F., Dunaif, A. & Spielman, R. S., Dec 1 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 12, p. 6623-6629 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Chromosomes
Drawing (graphics)
Genes
DNA sequences