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Research Output 1992 2019

2017
14 Citations (Scopus)

Pathogenic anti-Müllerian hormone variants in polycystic ovary syndrome

Gorsic, L. K., Kosova, G., Werstein, B., Sisk, R., Legro, R., Hayes, M. G., Teixeira, J. M., Dunaif, A. & Urbanek, M., Aug 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 8, p. 2862-2872 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Hormones
Steroid 17-alpha-Hydroxylase
Biosynthesis
Androgens

Pharmacologic Treatment of Polycystic Ovary Syndrome: Alternate and Future Paths

Duguech, L. M. M. & Legro, R., Jul 1 2017, In : Seminars in Reproductive Medicine. 35, 4, p. 326-343 18 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Therapeutics
Drug Repositioning
Anovulation
Secretory Pathway
2 Citations (Scopus)

Preconceptional antithyroid peroxidase antibodies, but not thyroid-stimulating hormone, are associated with decreased live birth rates in infertile women

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Nov 1 2017, In : Fertility and sterility. 108, 5, p. 843-850 8 p.

Research output: Contribution to journalArticle

Birth Rate
Live Birth
Thyrotropin
Peroxidase
Spontaneous Abortion
13 Citations (Scopus)

Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype

the, Reproductive Medicine Network & Reproductive Medicine Network, May 2017, In : American journal of obstetrics and gynecology. 216, 5, p. 493.e1-493.e13

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Phenotype
Hispanic Americans
Type 2 Diabetes Mellitus
Insulin Resistance

Reply: "weight and See" is not an option: Birds of a feather

Legro, R., Oct 1 2017, In : Human Reproduction. 32, 10, 1 p.

Research output: Contribution to journalLetter

Feathers
Birds
Weights and Measures
2 Citations (Scopus)
Sexual Maturation
Polycystic Ovary Syndrome
Glucose Tolerance Test
Nuclear Family
6 Citations (Scopus)

Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility

Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Aug 1 2017, In : American journal of obstetrics and gynecology. 217, 2, p. 191.e1-191.e19

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Androgens
Equipment and Supplies
Testosterone
1 Citation (Scopus)
Frontotemporal Lobar Degeneration
Estrogens
Dementia
Consensus
Extremities
30 Citations (Scopus)

Treatment strategies for women with WHO group II anovulation: Systematic review and network meta-analysis

Wang, R., Kim, B. V., Van Wely, M., Johnson, N. P., Costello, M. F., Zhang, H., Ng, E. H. Y., Legro, R., Bhattacharya, S., Norman, R. J. & Mol, B. W. J., Jan 1 2017, In : BMJ (Online). 356, j138.

Research output: Contribution to journalArticle

letrozole
Anovulation
Clomiphene
Metformin
Ovulation
2016
2 Citations (Scopus)

A multi-center randomized trial of two different intravenous fluids during labor

Dapuzzo-Argiriou, L. M., Smulian, J. C., Rochon, M. L., Galdi, L., Kissling, J. M., Schnatz, P. F., Gonzalez Rios, A., Airoldi, J., Carrillo, M. A., Maines, J., Kunselman, A., Repke, J. & Legro, R., Jan 17 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

Glucose
Dilatation
Birth Rate
Internship and Residency
Obstetrics
4 Citations (Scopus)

Association study of androgen signaling pathway genes in polycystic ovary syndrome

Ketefian, A., Jones, M. R., Krauss, R. M., Chen, Y. D. I., Legro, R., Azziz, R. & Goodarzi, M. O., Feb 1 2016, In : Fertility and sterility. 105, 2, p. 467-473.e4

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Genes
Single Nucleotide Polymorphism
Androgen Receptors
5 Citations (Scopus)

Baseline AMH level associated with ovulation following ovulation induction in women with polycystic ovary syndrome

Mumford, S. L., Legro, R. S., Diamond, M. P., Coutifaris, C., Steiner, A. Z., Schlaff, W. D., Alvero, R., Christman, G. M., Casson, P. R., Huang, H., Santoro, N., Eisenberg, E., Zhang, H. & Cedars, M. I., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3288-3296 9 p.

Research output: Contribution to journalArticle

Ovulation Induction
Polycystic Ovary Syndrome
Ovulation
Hormones
Serum
33 Citations (Scopus)

Benefit of delayed fertility therapy with preconception weight loss over immediate therapy in obese women with PCOS

Legro, R. S., Dodson, W. C., Kunselman, A. R., Stetter, C. M., Kris-Etherton, P. M., Williams, N. I., Gnatuk, C. L., Estes, S. J., Allison, K. C., Sarwer, D. B., Diamond, M. P., Schlaff, W. D., Casson, P. R., Christman, G. M., Barnhart, K. T., Wright Bates, G., Usadi, R., Lucidi, S., Baker, V., Zhang, H. & 3 others, Eisenberg, E., Coutifaris, C. & Dokras, A., Jul 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 7, p. 2658-2666 9 p.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Fertility
Weight Loss
Oral Contraceptives
1 Citation (Scopus)

Case 28-2016: A 31-year-old woman with infertility

Legro, R., Hurtado, R. M., Kilcoyne, A. & Roberts, D. J., Sep 15 2016, In : New England Journal of Medicine. 375, 11, p. 1069-1077 9 p.

Research output: Contribution to journalArticle

Urogenital Tuberculosis
Hysterosalpingography
Female Infertility
Nepal
Fallopian Tubes

Chinese Obstetrics & Gynecology journal club: A randomised controlled trial

Tsui, I. K., Dodson, W., Kunselman, A., Kuang, H., Han, F. J., Legro, R. & Wu, X. K., Jan 1 2016, In : BMJ open. 6, 1, e010178.

Research output: Contribution to journalArticle

Gynecology
Obstetrics
Randomized Controlled Trials
Oral Diagnosis
Hospital Obstetrics and Gynecology Department

Clarisa R. Gracia, MD, MSCE

Legro, R., Nov 1 2016, In : Seminars in Reproductive Medicine. 34, 6, p. 313-314 2 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Combined hormonal contraception use in reproductive-age women with contraindications to estrogen use

Lauring, J. R., Lehman, E. B., Deimling, T. A., Legro, R. S. & Chuang, C. H., Sep 1 2016, In : American journal of obstetrics and gynecology. 215, 3, p. 330.e1-330.e7

Research output: Contribution to journalArticle

Contraceptive Agents
Contraception
Estrogens
Migraine with Aura
Venous Thromboembolism
2 Citations (Scopus)
Type 2 Diabetes Mellitus
Clinical Trials
Pharmaceutical Preparations
Pregnancy
Fertility
14 Citations (Scopus)

Fertility-related quality of life from two RCT cohorts with infertility: Unexplained infertility and polycystic ovary syndrome

Santoro, N., Eisenberg, E., Trussell, J. C., Craig, L. B., Gracia, C., Huang, H., Alvero, R., Casson, P., Christman, G., Coutifaris, C., Diamond, M., Jin, S., Legro, R., Robinson, R. D., Schlaff, W. D. & Zhang, H., Oct 1 2016, In : Human Reproduction. 31, 10, p. 2268-2279 12 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Fertility
Quality of Life
letrozole
141 Citations (Scopus)

Fresh versus frozen embryos for infertility in the polycystic ovary syndrome

Chen, Z. J., Shi, Y., Sun, Y., Zhang, B., Liang, X., Cao, Y., Yang, J., Liu, J., Wei, D., Weng, N., Tian, L., Hao, C., Yang, D., Zhou, F., Shi, J., Xu, Y., Li, J., Yan, J., Qin, Y., Zhao, H. & 2 others, Zhang, H. & Legro, R., Aug 11 2016, In : New England Journal of Medicine. 375, 6, p. 523-533 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Embryo Transfer
Infertility
Embryonic Structures
Live Birth
10 Citations (Scopus)

Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome

Torchen, L. C., Kumar, A., Kalra, B., Savjani, G., Sisk, R., Legro, R. & Dunaif, A., Jul 1 2016, In : Fertility and sterility. 106, 1, p. 50-55 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Hormones
Fathers
Siblings
Control Groups
8 Citations (Scopus)
Onions
Embryo Transfer
Fertilization in Vitro
Live Birth
Genetic Testing

Lessons from Genome Wide Association Studies

Legro, R., Jul 1 2016, In : Seminars in Reproductive Medicine. 34, 4, 1 p.

Research output: Contribution to journalEditorial

Genome-Wide Association Study

Lifestyle in Reproductive Medicine

Legro, R., Mar 1 2016, In : Seminars in reproductive medicine. 34, 2, p. 63-64 2 p.

Research output: Contribution to journalEditorial

Reproductive Medicine
Pregnancy Complications
Risk Reduction Behavior
Infertility
Health Status
5 Citations (Scopus)

Mr. Fertility authority, tear down that weight wall!

Legro, R. S., Jan 1 2016, In : Human Reproduction. 31, 12, p. 2662-2664 3 p.

Research output: Contribution to journalComment/debate

25 Citations (Scopus)

Ovulation induction in polycystic ovary syndrome: Current options

Legro, R., Nov 1 2016, In : Best Practice and Research: Clinical Obstetrics and Gynaecology. 37, p. 152-159 8 p.

Research output: Contribution to journalReview article

Ovulation Induction
Polycystic Ovary Syndrome
Clomiphene
letrozole
Metformin
171 Citations (Scopus)

Polycystic ovary syndrome

Azziz, R., Carmina, E., Chen, Z., Dunaif, A., Laven, J. S. E., Legro, R., Lizneva, D., Natterson-Horowtiz, B., Teede, H. J. & Yildiz, B. O., Aug 11 2016, In : Nature Reviews Disease Primers. 2, 16057.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Hyperandrogenism
Androgens
Gestational Diabetes
Pregnancy Complications
19 Citations (Scopus)

Predictors of pregnancy and live-birth in couples with unexplained infertility after ovarian stimulation–intrauterine insemination

for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network, Jun 1 2016, In : Fertility and sterility. 105, 6, p. 1575-1583.e2

Research output: Contribution to journalArticle

Insemination
Live Birth
Infertility
Ovulation Induction
Pregnancy
1 Citation (Scopus)

The authors reply

Chen, Z. J. & Legro, R., Nov 17 2016, In : New England Journal of Medicine. 375, 20, p. e42

Research output: Contribution to journalLetter

93 Citations (Scopus)

The management of anovulatory infertility in women with polycystic ovary syndrome: An analysis of the evidence to support the development of global WHO guidance

Balen, A. H., Morley, L. C., Misso, M., Franks, S., Legro, R., Wijeyaratne, C. N., Stener-Victorin, E., Fauser, B. C. J. M., Norman, R. J. & Teede, H., Nov 1 2016, In : Human Reproduction Update. 22, 6, p. 687-708 22 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Ovulation Induction
Life Style
Metformin
8 Citations (Scopus)

Treatment strategies for infertile women with polycystic ovary syndrome

Vitek, W., Hoeger, K. & Legro, R., Aug 1 2016, In : Minerva Ginecologica. 68, 4, p. 450-457 8 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Infertility
Ovulation Induction
Ovulation
Hyperandrogenism
25 Citations (Scopus)

Vitamin D status relates to reproductive outcome in women with polycystic ovary syndrome: Secondary analysis of a multicenter randomized controlled trial

Pal, L., Zhang, H., Williams, J., Santoro, N. F., Diamond, M. P., Schlaff, W. D., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. & Legro, R. S., Aug 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3027-3035 9 p.

Research output: Contribution to journalArticle

Ovulation Induction
Polycystic Ovary Syndrome
Live Birth
Vitamin D
Randomized Controlled Trials
28 Citations (Scopus)

Weight loss and lowering androgens predict improvements in health-related quality of life in women with PCOS

Dokras, A., Sarwer, D. B., Allison, K. C., Milman, L., Kris-Etherton, P. M., Kunselman, A. R., Stetter, C. M., Williams, N. I., Gnatuk, C. L., Estes, S. J., Fleming, J., Coutifaris, C. & Legro, R. S., Aug 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 2966-2974 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Weight Loss
Quality of Life
Health
2015
112 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Insulin Resistance
127 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Anovulation
19 Citations (Scopus)

Assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial: Baseline characteristics

Diamond, M. P., Legro, R. S., Coutifaris, C., Alvero, R., Robinson, R. D., Casson, P., Christman, G. M., Ager, J., Huang, H., Hansen, K. R., Baker, V., Usadi, R., Seungdamrong, A., Bates, G. W., Rosen, R. M., Haisonleder, D., Krawetz, S. A., Barnhart, K., Trussell, J. C., Jin, Y. & 74 others, Santoro, N., Eisenberg, E., Zhang, H., Bartlebaugh, C., Dodson, W., Estes, S., Gnatuk, C., Ladda, R., Ober, J., Easton, C., Hernandez, A., Leija, M., Pierce, D., Brzyski, R., Awonuga, A., Cedo, L., Cline, A., Collins, K., Puscheck, E., Singh, M., Yoscovits, M., Lecks, K., Martino, L., Marunich, R., Comfort, A., Crow, M., Hohmann, A., Mallette, S., Smith, Y., Randolph, J., Fisseha, S., Ringbloom, M., Tang, J., Mason, S., Di Maria, N., Laylor, B., Martinez, L., Solnica, A., Wojtczuk, A., Rhea, M., Turner, K., Craig, L. B., Zornes, C., Rodriguez, M. R., Hunt, T. S., Remble, T., Cheng, G., Green, L., Lenhart, N., Del Basso, D., Brennan, M., Kuang, H., Li, Y., Patrizio, P., Sakai, L., Song, C., Taylor, H., Thomas, T., Yan, Q., Zhang, M., Lamar, C., De Paolo, L., Guzick, D., Herring, A., Redmond, J. B., Thomas, M., Turek, P., Wactawski-Wende, J., Rebar, R., Cato, P., Dukic, V., Lewis, V., Schlegel, P. & Witter, F., Jan 1 2015, In : Fertility and sterility. 103, 4, p. 962-973.e4

Research output: Contribution to journalArticle

Ovulation Induction
letrozole
Infertility
Pregnancy
Clomiphene
14 Citations (Scopus)

Chlamydia trachomatis immunoglobulin G3 seropositivity is a predictor of reproductive outcomes in infertile women with patent fallopian tubes

Steiner, A. Z., Diamond, M. P., Legro, R., Schlaff, W. D., Barnhart, K. T., Casson, P. R., Christman, G. M., Alvero, R., Hansen, K. R., Geisler, W. M., Thomas, T., Santoro, N., Zhang, H. & Eisenberg, E., Jan 1 2015, In : Fertility and sterility. 104, 6, p. 1522-1526 5 p.

Research output: Contribution to journalArticle

Fallopian Tubes
Chlamydia trachomatis
Immunoglobulins
Immunoglobulin G
Confidence Intervals
20 Citations (Scopus)

Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

Hayes, M. G., Urbanek, M., Ehrmann, D. A., Armstrong, L. L., Lee, J. Y., Sisk, R., Karaderi, T., Barber, T. M., McCarthy, M. I., Franks, S., Lindgren, C. M., Welt, C. K., Diamanti-Kandarakis, E., Panidis, D., Goodarzi, M. O., Azziz, R., Zhang, Y., James, R. G., Olivier, M., Kissebah, A. H. & 4 others, Reproductive Medicine Network, M. N., Stener-Victorin, E., Legro, R. S. & Dunaif, A., Aug 18 2015, In : Nature communications. 7, 10762.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Diagnosis and treatment of polycystic ovary syndrome (PCOS): An interview with Richard Legro

Legro, R., Mar 27 2015, In : BMC Medicine. 13, 1, p. 1-5 5 p., 64.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Webcasts
Interviews
Therapeutics
Practice Guidelines

Functional genomics of PCOS: From GWAS to molecular mechanisms

McAllister, J., Legro, R., Modi, B. P. & Strauss, J. F., Sep 1 2015, In : Obstetrical and Gynecological Survey. 70, 9, p. 573-574 2 p.

Research output: Contribution to journalComment/debate

Genome-Wide Association Study
Genomics
55 Citations (Scopus)

Functional genomics of PCOS: From GWAS to molecular mechanisms

McAllister, J., Legro, R., Modi, B. P. & Strauss, J. F., Mar 1 2015, In : Trends in Endocrinology and Metabolism. 26, 3, p. 118-124 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Genome-Wide Association Study
Genomics
Androgens
Theca Cells
41 Citations (Scopus)

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genomewide association studies of chinese individuals

Brower, M. A., Jones, M. R., Rotter, J. I., Krauss, R. M., Legro, R. S., Azziz, R. & Goodarzi, M. O., Jan 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 1, p. E182-E186

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genes
Genome-Wide Association Study
Nucleotide Mapping
Polymorphism

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals

Brower, M. A., Jones, M. R., Rotter, J. I., Krauss, R. M., Legro, R. S., Azziz, R. & Goodarzi, M. O., Jan 1 2015, In : The Journal of clinical endocrinology and metabolism. 100, 1, p. E182-E186

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genome-Wide Association Study
Genes
Polymorphism
Nucleotide Mapping
97 Citations (Scopus)

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

Hayes, M. G., Urbanek, M., Ehrmann, D. A., Armstrong, L. L., Lee, J. Y., Sisk, R., Karaderi, T., Barber, T. M., McCarthy, M. I., Franks, S., Lindgren, C. M., Welt, C. K., Diamanti-Kandarakis, E., Panidis, D., Goodarzi, M. O., Azziz, R., Zhang, Y., James, R. G., Olivier, M., Kissebah, A. H. & 35 others, Stener-Victorin, E., Legro, R. S., Dunaif, A., Alvero, R., Barnhart, H. X., Baker, V., Barnhart, K. T., Bates, G. W., Brzyski, R. G., Carr, B. R., Carson, S. A., Casson, P., Cataldo, N. A., Christman, G., Coutifaris, C., Diamond, M. P., Eisenberg, E., Gosman, G. G., Giudice, L. C., Haisenleder, D. J., Huang, H., Krawetz, S. A., Lucidi, S., McGovern, P. G., Myers, E. R., Nestler, J. E., Ohl, D., Santoro, N., Schlaff, W. D., Snyder, P., Steinkampf, M. P., Trussell, J. C., Usadi, R., Yan, Q. & Zhang, H., Aug 18 2015, In : Nature communications. 6, 7502.

Research output: Contribution to journalArticle

ovaries
secretions
hormones
genome
Polycystic Ovary Syndrome

Global women's health: Challenges and opportunities

Legro, R., Jan 1 2015, In : Seminars in Reproductive Medicine. 33, 1, 1 p.

Research output: Contribution to journalEditorial

Women's Health
Gynecology
Obstetrics
Global Health
5 Citations (Scopus)

How do pregnancy intentions affect contraceptive choices when cost is not a factor? A study of privately insured women

Weisman, C. S., Lehman, E. B., Legro, R. S., Velott, D. L. & Chuang, C. H., Nov 1 2015, In : Contraception. 92, 5, p. 501-507 7 p.

Research output: Contribution to journalArticle

Contraceptive Agents
Contraception
Costs and Cost Analysis
Pregnancy
Prescriptions
5 Citations (Scopus)

Identification and replication of prediction models for ovulation, pregnancy and live birth in infertile women with polycystic ovary syndrome

Kuang, H., Jin, S., Hansen, K. R., Diamond, M. P., Coutifaris, C., Casson, P., Christman, G., Alvero, R., Huang, H., Bates, G. W., Usadi, R., Lucidi, S., Baker, V., Santoro, N., Eisenberg, E., Legro, R. & Zhang, H., Apr 9 2015, In : Human Reproduction. 30, 9, p. 2222-2233 12 p.

Research output: Contribution to journalArticle

Ovulation Prediction
Polycystic Ovary Syndrome
Live Birth
Pregnancy Outcome
Ovulation
11 Citations (Scopus)

Impact of male and female weight, smoking, and intercourse frequency on live birth in women with polycystic ovary syndrome

Polotsky, A. J., Allshouse, A. A., Casson, P. R., Coutifaris, C., Diamond, M. P., Christman, G. M., Schlaff, W. D., Alvero, R., Trussell, J. C., Krawetz, S. A., Santoro, N., Eisenberg, E., Zhang, H. & Legro, R. S., Jun 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 6, p. 2405-2412 8 p.

Research output: Contribution to journalArticle

letrozole
Clomiphene
Polycystic Ovary Syndrome
Live Birth
Smoking
1 Citation (Scopus)

In defense of publishing baseline data from clinical trials

Legro, R., Jan 1 2015, In : Fertility and sterility. 103, 4, p. 902-903 2 p.

Research output: Contribution to journalEditorial

Female Fertility Agents
Female Infertility
Multiple Pregnancy
Clomiphene
Nitriles

Inflammatory Factors in Reproductive Medicine

Legro, R., Jul 3 2015, In : Seminars in Reproductive Medicine. 33, 4, 1 p.

Research output: Contribution to journalEditorial

Reproductive Medicine
Inflammation