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Research Output 1992 2019

2015

Innovations in reproductive endocrinology: A tribute to Bruce Carr, MD

Bulun, S. E. & Legro, R., May 4 2015, In : Seminars in Reproductive Medicine. 33, 3, 1 p.

Research output: Contribution to journalEditorial

21st Century History
20th Century History
Reproductive Medicine
Endocrinology
Obstetrics
1 Citation (Scopus)

Introduction: On-label and off-label drug use in reproductive medicine

Legro, R., Mar 1 2015, In : Fertility and Sterility. 103, 3, p. 581-582 2 p.

Research output: Contribution to journalArticle

Off-Label Use
Reproductive Medicine
Pharmaceutical Preparations
Prescription Drugs
Vulnerable Populations
1 Citation (Scopus)

Joy in moment of revelation: A cure for burn-out

Legro, R., Jan 1 2015, In : Fertility and sterility. 104, 6, p. 1372-1373 2 p.

Research output: Contribution to journalEditorial

Professional Burnout
Job Description
Attitude of Health Personnel
Career Choice
Reproductive Medicine
89 Citations (Scopus)

Letrozole, gonadotropin, or clomiphene for unexplained infertility

The NICHD Reproductive Medicine Network, Sep 24 2015, In : New England Journal of Medicine. 373, 13, p. 1230-1240 11 p.

Research output: Contribution to journalArticle

letrozole
Clomiphene
Gonadotropins
Infertility
Pregnancy

Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility

Diamond, M. P., Legro, R., Coutifaris, C., Alvero, R., Robinson, R. D., Casson, P., Christman, G. M., Ager, J., Huang, H., Hansen, K. R., Baker, V., Usadi, R., Seungdamrong, A., Wright Bates, G., Rosen, R. M., Haisenleder, D., Krawetz, S. A., Barnhart, K., Trussell, J. C., Ohl, D. & 4 others, Jin, Y., Santoro, N., Eisenberg, E. & Zhang, H., Dec 1 2015, In : Obstetrical and Gynecological Survey. 70, 12, p. 757-758 2 p.

Research output: Contribution to journalComment/debate

letrozole
Clomiphene
Gonadotropins
Infertility

Letrozole versus clomiphene for infertility in the polycystic ovary syndrome

Legro, R., Brzyski, R. G., Diamond, M. P., Coutifaris, C., Schlaff, W. D., Casson, P., Christman, G. M., Huang, H., Yan, Q., Alvero, R., Haisenleder, D. J., Barnhart, K. T., Bates, G. W., Usadi, R., Lucidi, S., Baker, V., Trussell, J. C., Krawetz, S. A., Snyder, P., Ohl, D. & 3 others, Santoro, N., Eisenberg, E. & Zhang, H., Jan 1 2015, In : Obstetrical and Gynecological Survey. 69, 10, p. 599-601 3 p.

Research output: Contribution to journalComment/debate

letrozole
Clomiphene
Polycystic Ovary Syndrome
Infertility
37 Citations (Scopus)
Caloric Restriction
Glucuronides
Menstrual Cycle
Weight Loss
Pregnanediol
6 Citations (Scopus)

Mindfulness-based stress reduction for overweight/obese women with and without polycystic ovary syndrome: Design and methods of a pilot randomized controlled trial

Raja-Khan, N., Agito, K., Shah, J., Stetter, C. M., Gustafson, T. S., Socolow, H., Kunselman, A., Reibel, D. K. & Legro, R., Mar 1 2015, In : Contemporary Clinical Trials. 41, p. 287-297 11 p.

Research output: Contribution to journalArticle

Mindfulness
Polycystic Ovary Syndrome
Randomized Controlled Trials
Blood Glucose
Ovary

Practices in in vitro fertilization

Legro, R., Mar 1 2015, In : Seminars in Reproductive Medicine. 33, 2, 1 p.

Research output: Contribution to journalEditorial

21st Century History
20th Century History
Reproductive Medicine
Quality of Health Care
Fertilization in Vitro
2 Citations (Scopus)

Predictors of participant retention in infertility treatment trials

Kuang, H., Jin, S., Thomas, T., Engmann, L., Hansen, K. R., Coutifaris, C., Casson, P., Christman, G., Alvero, R., Santoro, N., Eisenberg, E., Diamond, M. P., Legro, R. & Zhang, H., Nov 1 2015, In : Fertility and sterility. 104, 5, p. 1236-1243.e2

Research output: Contribution to journalArticle

Infertility
Randomized Controlled Trials
Insurance Coverage
letrozole
Alcohols
Polycystic Ovary Syndrome
Publications
Clinical Trials
Pregnancy
Multicenter Studies
63 Citations (Scopus)

Randomized controlled trial of preconception interventions in infertile women with polycystic ovary syndrome

Legro, R., Dodson, W., Kris-Etherton, P. M., Kunselman, A., Stetter, C. M., Williams, N., Gnatuk, C., Estes, S., Fleming, J. A., Allison, K. C., Sarwer, D. B., Coutifaris, C. & Dokras, A., Nov 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 11, p. 4048-4058 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Oral Contraceptives
Randomized Controlled Trials
Life Style
Weight Loss
2 Citations (Scopus)

Recruitment strategies in two reproductive medicine network infertility trials

for the Reproductive Medicine Network, Nov 1 2015, In : Contemporary Clinical Trials. 45, p. 196-200 5 p.

Research output: Contribution to journalArticle

Reproductive Medicine
Infertility
Ovulation Induction
Radio
Pregnancy
10 Citations (Scopus)
life planning
women's studies
Contraceptive Agents
contraceptive
pregnancy
Infertility
Clinical Trials
Infertility
Clinical Trials
Pregnancy
171 Citations (Scopus)

Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome

Dumesic, D. A., Oberfield, S. E., Stener-Victorin, E., Marshall, J. C., Laven, J. S. & Legro, R. S., Jan 1 2015, In : Endocrine Reviews. 36, 5, p. 487-525 39 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Hyperandrogenism
Molecular Biology
Epidemiology
Phenotype
13 Citations (Scopus)

Time-related increase in urinary testosterone levels and stable semen analysis parameters after bariatric surgery in men

Legro, R., Kunselman, A., Meadows, J. W., Kesner, J. S., Krieg, E. F., Rogers, A. & Cooney, R. N., Feb 1 2015, In : Reproductive BioMedicine Online. 30, 2, p. 150-156 7 p.

Research output: Contribution to journalArticle

Semen Analysis
Bariatric Surgery
Testosterone
Weight Loss
Gastric Bypass
17 Citations (Scopus)

Women's awareness of their contraceptive benefits under the patient protection and affordable care act

Chuang, C. H., Mitchell, J. L., Velott, D. L., Legro, R. S., Lehman, E. B., Confer, L. & Weisman, C. S., Nov 1 2015, In : American journal of public health. 105, p. S713-S715

Research output: Contribution to journalArticle

Patient Protection and Affordable Care Act
Contraceptive Agents
Contraception
Tubal Sterilization
Intrauterine Devices
2014
2 Citations (Scopus)

A patient's guide: polycystic ovary syndrome (PCOS).

Hoeger, K. M., Legro, R. S. & Welt, C. K., Jan 2014, In : Unknown Journal. 99, 1, p. 35A-36A

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Young Adult
Differential Diagnosis
Endocrine Diagnostic Techniques
2 Citations (Scopus)

Effects and mechanisms of complementary and alternative medicine during the reproductive process

Wu, X., Ng, E. H. Y., Stener-Victorin, E. & Legro, R., Jan 1 2014, In : Evidence-based Complementary and Alternative Medicine. 2014, 698921.

Research output: Contribution to journalEditorial

Complementary Therapies
9 Citations (Scopus)

Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome

Liu, D. M., Torchen, L. C., Sung, Y., Paparodis, R., Legro, R., Grebe, S. K., Singh, R. J., Taylor, R. L. & Dunaif, A., Jun 26 2014, In : Human Reproduction. 29, 12, p. 2764-2772 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Gonadotropins
Siblings
Androstenedione
Gonadotropin-Releasing Hormone
34 Citations (Scopus)

High-dose vitamin D supplementation and measures of insulin sensitivity in polycystic ovary syndrome: A randomized, controlled pilot trial

Raja-Khan, N., Shah, J., Stetter, C. M., Lott, M. E. J., Kunselman, A., Dodson, W. & Legro, R., Jan 1 2014, In : Fertility and Sterility. 101, 6, p. 1740-1746 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Vitamin D
Insulin Resistance
Randomized Controlled Trials
Placebos
19 Citations (Scopus)

Hyperandrogenic oligomenorrhea and metabolic risks across menopausal transition

Polotsky, A. J., Allshouse, A. A., Crawford, S. L., Harlow, S. D., Khalil, N., Kazlauskaite, R., Santoro, N. & Legro, R., Jan 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 6, p. 2120-2127 8 p.

Research output: Contribution to journalArticle

Oligomenorrhea
Hazards
Androgens
Menopause
Health
36 Citations (Scopus)

Improving the reporting of Clinical trials of infertility treatments (IMPRINT): Modifying the CONSORT statement

Legro, R., Wu, X., Barnhart, K. T., Farquhar, C., Fauser, B. C. J. M. & Mol, B., Jan 1 2014, In : Human Reproduction. 29, 10, p. 2075-2082 8 p.

Research output: Contribution to journalArticle

Infertility
Clinical Trials
Live Birth
Pregnancy
Therapeutics
33 Citations (Scopus)

Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): Modifying the CONSORT statement

Harbin Consensus Conference Workshop Group, Oct 1 2014, In : Fertility and sterility. 102, 4, p. 952-959.e15

Research output: Contribution to journalArticle

Infertility
Clinical Trials
Live Birth
Pregnancy
Therapeutics
7 Citations (Scopus)

Introduction: Germline stem cell therapy in humans: Two are not enough

Legro, R. & Adashi, E. Y., Jan 1 2014, In : Fertility and sterility. 101, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Stem Cell Research
Cell- and Tissue-Based Therapy
Stem Cells
Oogonial Stem Cells
4 Citations (Scopus)

Introduction: Choosing the main outcome of an infertility trial is harder than you think

Legro, R. & Wu, X., Jan 1 2014, In : Fertility and Sterility. 101, 5, p. 1201-1202 2 p.

Research output: Contribution to journalArticle

Infertility
Live Birth
Germ Cells
Patient Care
Public Health
1 Citation (Scopus)

Letrozole or clomiphene for infertility in the polycystic ovary syndrome.

Legro, R., Zhang, H. & Eunice Kennedy Shriver NICHD Reproductive Medicine Network, K. S. NICHD. R. M. N., Jan 1 2014, In : The New England journal of medicine. 371, 15, p. 1463-1464 2 p.

Research output: Contribution to journalComment/debate

letrozole
Female Fertility Agents
Female Infertility
Clomiphene
Nitriles
194 Citations (Scopus)

Letrozole versus clomiphene for infertility in the polycystic ovary syndrome

Legro, R., Brzyski, R. G., Diamond, M. P., Coutifaris, C., Schlaff, W. D., Casson, P., Christman, G. M., Huang, H., Yan, Q., Alvero, R., Haisenleder, D. J., Barnhart, K. T., Wright Bates, G., Usadi, R., Lucidi, S., Baker, V., Trussell, J. C., Krawetz, S. A., Snyder, P., Ohl, D. & 3 others, Santoro, N., Eisenberg, E. & Zhang, H., Jan 1 2014, In : New England Journal of Medicine. 371, 2, p. 119-129 11 p.

Research output: Contribution to journalArticle

letrozole
Clomiphene
Polycystic Ovary Syndrome
Infertility
Live Birth
17 Citations (Scopus)
Polycystic Ovary Syndrome
Embryo Transfer
Cryopreservation
Live Birth
Fertilization in Vitro
87 Citations (Scopus)

Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype

McAllister, J., Modi, B., Miller, B. A., Biegler, J., Bruggeman, R., Legro, R. & Strauss, J. F., Apr 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 15

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Protein Isoforms
Theca Cells
Phenotype
Cholesterol Side-Chain Cleavage Enzyme
9 Citations (Scopus)

Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome

Kobaly, K., Vellanki, P., Sisk, R. K., Armstrong, L., Lee, J. Y., Lee, J., Hayes, M. G., Urbanek, M., Legro, R. & Dunaif, A., Jan 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 8, p. 2961-2966 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Fasting
Homeostasis
Mothers
Glucose
9 Citations (Scopus)

Smoking in infertile women with polycystic ovary syndrome: Baseline validation of self-report and effects on phenotype

Legro, R., Chen, G., Kunselman, A., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., Mcgovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R., Zhang, H. & Foulds, J., Jun 26 2014, In : Human Reproduction. 29, 12, p. 2680-2686 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Self Report
Smoking
Phenotype
Cotinine
8 Citations (Scopus)

The authors reply

Legro, R. & Zhang, H., Jan 1 2014, In : New England Journal of Medicine. 371, 15, p. 1463-1464 2 p.

Research output: Contribution to journalLetter

Female Fertility Agents
Female Infertility
Clomiphene
Nitriles
Triazoles
4 Citations (Scopus)

The inflammatory gene pathway is not a major contributor to polycystic ovary snydrome

Bhatt, S., Mutharasan, P., Garcia, O. A., Jafari, N., Legro, R., Dunaif, A. & Urbanek, M., Jan 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 3

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Polymorphism
Ovary
Nucleotides
Genes
27 Citations (Scopus)

The pregnancy in polycystic ovary syndrome II study: Baseline characteristics and effects of obesity from a multicenter randomized clinical trial

Legro, R., Brzyski, R. G., Diamond, M. P., Coutifaris, C., Schlaff, W. D., Alvero, R., Casson, P., Christman, G. M., Huang, H., Yan, Q., Haisenleder, D. J., Barnhart, K. T., Bates, G. W., Usadi, R., Lucidi, R., Baker, V., Trussell, J. C., Krawetz, S. A., Snyder, P., Ohl, D. & 3 others, Santoro, N., Eisenberg, E. & Zhang, H., Jan 1 2014, In : Fertility and sterility. 101, 1

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Randomized Controlled Trials
Obesity
Pregnancy
letrozole
38 Citations (Scopus)

The role of TGF-β in polycystic ovary syndrome

Raja-Khan, N., Urbanek, M., Rodgers, R. J. & Legro, R., Jan 1 2014, In : Reproductive Sciences. 21, 1, p. 20-31 12 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Transforming Growth Factors
Extracellular Matrix
Cardiovascular Abnormalities
Microfibrils

Women's health initiative

Legro, R., 2014, In : Seminars in Reproductive Medicine. 32, 6, p. 417 1 p.

Research output: Contribution to journalEditorial

Women's Health Services
Women's Health
Cardiovascular Diseases
2013
24 Citations (Scopus)

Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: Study design of a randomized controlled trial

Kuang, H., Li, Y., Wu, X., Hou, L., Wu, T., Liu, J., Ng, E. H. Y., Stener-Victorin, E., Legro, R. & Zhang, H., Sep 23 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 527303.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Live Birth
Acupuncture
Randomized Controlled Trials
622 Citations (Scopus)

Diagnosis and treatment of polycystic ovary syndrome: An endocrine society clinical practice guideline

Legro, R., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R. & Welt, C. K., Dec 1 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 12, p. 4565-4592 28 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Contraceptive Agents
Practice Guidelines
Androgens
1 Citation (Scopus)

Effect of adolescent pregnancy on final adult height in non-Hispanic white women

Pauli, J., Lloyd, T., Kunselman, A., Stetter, C. M., Dodson, W. & Legro, R., Sep 1 2013, In : Archives of Gynecology and Obstetrics. 288, 3, p. 679-682 4 p.

Research output: Contribution to journalArticle

Pregnancy in Adolescence
Birth Order
Live Birth
Parturition
Nutrition Surveys
77 Citations (Scopus)

Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry

Mutharasan, P., Galdones, E., Bernabé, B. P., Garcia, O. A., Jafari, N., Shea, L. D., Woodruff, T. K., Legro, R. S., Dunaif, A. & Urbanek, M., Jan 1 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 1, p. E185-E190

Research output: Contribution to journalArticle

FSH Receptors
Polycystic Ovary Syndrome
Chromosomes
Genes
Chorionic Gonadotropin
1 Citation (Scopus)

Familial aggregation of circulating c-reactive protein in polycystic ovary syndrome

Sasidevi, A., Vellanki, P., Kunselman, A., Raja-Khan, N., Dunaif, A. & Legro, R., Jan 1 2013, In : Human Reproduction. 28, 3, p. 770-776 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
C-Reactive Protein
Proteins
Sample Size
Siblings

Introduction: Back to the future: Origins of polycystic ovary syndrome

Legro, R., Jan 1 2013, In : Fertility and Sterility. 100, 1, 1 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Pregnancy

Introduction to the guest editor: Marcelle Cedars, MD

Legro, R., Oct 16 2013, In : Seminars in Reproductive Medicine. 31, 6, 1 p.

Research output: Contribution to journalEditorial

39 Citations (Scopus)

Longterm management of Polycystic Ovarian Syndrome (PCOS)

Bates, G. W. & Legro, R., Jul 5 2013, In : Molecular and Cellular Endocrinology. 373, 1-2, p. 91-97 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Metformin
Medical problems
Oral Contraceptives
Risk assessment
24 Citations (Scopus)

Ovulation induction in women with polycystic ovary syndrome

Perales-Puchalt, A. & Legro, R., Jan 1 2013, In : Steroids. 78, 8, p. 767-772 6 p.

Research output: Contribution to journalReview article

Selective Estrogen Receptor Modulators
Aromatase Inhibitors
Ovulation Induction
Polycystic Ovary Syndrome
Gonadotropins

Polycystic ovary syndrome across racial and ethnic groups

Engmann, L. & Legro, R., Mar 1 2013, Ethnic Differences in Fertility and Assisted Reproduction. Springer New York, p. 185-199 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polycystic Ovary Syndrome
Ethnic Groups
Population
Public Health
Phenotype
15 Citations (Scopus)

Sildenafil citrate in the treatment of pain in primary dysmenorrhea: A randomized controlled trial

Dmitrovic, R., Kunselman, A. & Legro, R., Jan 1 2013, In : Human Reproduction. 28, 11, p. 2958-2965 8 p.

Research output: Contribution to journalArticle

Dysmenorrhea
Randomized Controlled Trials
Pain
Placebos
Therapeutics