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Research Output 1992 2019

2013
2 Citations (Scopus)

The quality of ovulation is strained in normal women

Legro, R., Jan 1 2013, In : Human Reproduction. 28, 6, p. 1446-1447 2 p.

Research output: Contribution to journalComment/debate

Anovulation
Luteinizing Hormone
Ovulation
Progesterone
Estradiol
2012
5 Citations (Scopus)

A good meta-analysis is hard to find

Legro, R. & Kunselman, A., Jan 1 2012, In : Fertility and sterility. 97, 5, p. 1048-1049 2 p.

Research output: Contribution to journalEditorial

Female Fertility Agents
Female Infertility
Assisted Reproductive Techniques
Ovulation Induction
Luteinizing Hormone
6 Citations (Scopus)

Altering hirsutism through ovulation induction in women with polycystic ovary syndrome

Roth, L. W., Huang, H., Legro, R., Diamond, M. P., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R., Zhang, H. & Schlaff, W. D., Jun 1 2012, In : Obstetrics and Gynecology. 119, 6, p. 1151-1156 6 p.

Research output: Contribution to journalArticle

Hirsutism
Ovulation Induction
Polycystic Ovary Syndrome
Clomiphene
Metformin

Androgen excess disorders

Legro, R. & Azziz, R., Mar 27 2012, Danforth's Obstetrics and Gynecology: Tenth Edition. Wolters Kluwer Health Adis (ESP), p. 682-704 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Androgens
4 Citations (Scopus)

Catechol-O-methyltransferase (COMT) single nucleotide polymorphisms and haplotypes are not major risk factors for polycystic ovary syndrome

Hill, L. D., Ewens, K. G., Maher, B. S., York, T. P., Legro, R., Dunaif, A. & Strauss, J. F., Mar 5 2012, In : Molecular and Cellular Endocrinology. 350, 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Polycystic Ovary Syndrome
Polymorphism
Haplotypes
Single Nucleotide Polymorphism
20 Citations (Scopus)

Cholesterol Side-Chain Cleavage Gene Expression in Theca Cells: Augmented Transcriptional Regulation and mRNA Stability in Polycystic Ovary Syndrome

Wickenheisser, J. K., Biegler, J. M., Nelson-DeGrave, V. L., Legro, R., Strauss, J. F. & McAllister, J., Nov 14 2012, In : PloS one. 7, 11, e48963.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Cholesterol Side-Chain Cleavage Enzyme
Theca Cells
Polycystic Ovary Syndrome
RNA Stability
186 Citations (Scopus)

Consensus on womens health aspects of polycystic ovary syndrome (PCOS)

Fauser, B. C. J. M., Tarlatzis, B. C., Rebar, R. W., Legro, R., Balen, A. H., Lobo, R., Carmina, H., Chang, R. J., Yildiz, B. O., Laven, J. S. E., Boivin, J., Petraglia, F., Wijeyeratne, C. N., Norman, R. J., Dunaif, A., Franks, S., Wild, R. A., Dumesic, D. & Barnhart, K., Jan 1 2012, In : Human Reproduction. 27, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Women's Health
Consensus Development Conferences
Hirsutism
Pregnancy Complications
687 Citations (Scopus)

Consensus on women's health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

Fauser, B. C. J. M., Tarlatzis, B. C., Rebar, R. W., Legro, R., Balen, A. H., Lobo, R., Carmina, E., Chang, J., Yildiz, B. O., Laven, J. S. E., Boivin, J., Petraglia, F., Wijeyeratne, C. N., Norman, R. J., Dunaif, A., Franks, S., Wild, R. A., Dumesic, D. & Barnhart, K., Jan 1 2012, In : Fertility and sterility. 97, 1

Research output: Contribution to journalArticle

Consensus Development Conferences
Polycystic Ovary Syndrome
Women's Health
Hirsutism
Pregnancy Complications
30 Citations (Scopus)

Continuous compared with cyclic oral contraceptives for the treatment of primary dysmenorrhea: A randomized controlled trial

Dmitrovic, R., Kunselman, A. & Legro, R., Jun 1 2012, In : Obstetrics and Gynecology. 119, 6, p. 1143-1150 8 p.

Research output: Contribution to journalArticle

Dysmenorrhea
Oral Contraceptives
Randomized Controlled Trials
Visual Analog Scale
Pain

Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome

Dmitrovic, R., Kunselman, A. & Legro, R., Feb 1 2012, In : Obstetrics and Gynecology. 119, 2 PART 1, 1 p.

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
Glucose
Pregnancy

Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome

Dmitrovic, R., Kunselman, A. & Legro, R., Jan 1 2012, In : Obstetrics and Gynecology. 119, 2, 1 p.

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
Glucose
Pregnancy
10 Citations (Scopus)

Determination of vitamin D in relation to body mass index and race in a defined population of black and white women

Coney, P., Demers, L., Dodson, W., Kunselman, A., Ladson, G. & Legro, R., Jan 1 2012, In : International Journal of Gynecology and Obstetrics. 119, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Vitamin D
Body Mass Index
Population
Parathyroid Hormone
African Americans
2 Citations (Scopus)

Disclosure of duplicative studies: Damned if you don't

Legro, R., Niederberger, C. & Pellicer, A., Jan 1 2012, In : Fertility and Sterility. 98, 6, p. 1347-1349 3 p.

Research output: Contribution to journalArticle

Disclosure
Publication Bias
Observational Studies
Publications
Cohort Studies
55 Citations (Scopus)

Effects of gastric bypass surgery on female reproductive function

Legro, R. S., Dodson, W. C., Gnatuk, C. L., Estes, S. J., Kunselman, A. R., Meadows, J. W., Kesner, J. S., Krieg, E. F., Rogers, A. M., Haluck, R. S. & Cooney, R. N., Dec 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4540-4548 9 p.

Research output: Contribution to journalArticle

Gastric Bypass
Surgery
Pregnanediol
Hyperandrogenism
Follicular Phase
22 Citations (Scopus)

Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome

Witchel, S. F., Recabarren, S. E., González, F., Diamanti-Kandarakis, E., Cheang, K. I., Duleba, A. J., Legro, R., Homburg, R., Pasquali, R., Lobo, R. A., Zouboulis, C. C., Kelestimur, F., Fruzzetti, F., Futterweit, W., Norman, R. J. & Abbott, D. H., Dec 1 2012, In : Endocrine. 42, 3, p. 526-534 9 p.

Research output: Contribution to journalArticle

Patient Transfer
Polycystic Ovary Syndrome
Anovulation
Congenital Adrenal Hyperplasia
Hirsutism

Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome

Diamond, M. P., Kruger, M., Santoro, N., Zhang, H., Casson, P., Schlaff, W., Coutifaris, C., Brzyski, R., Christman, G., Carr, B. R., McGovern, P. G., Cataldo, N. A., Steinkampf, M. P., Gosman, G. G., Nestler, J. E., Carson, S., Myers, E. E., Eisenberg, E. & Legro, R. S., Sep 1 2012, In : Obstetrical and Gynecological Survey. 67, 9, p. 548-549 2 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Live Birth
34 Citations (Scopus)

Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome

Diamond, M. P., Kruger, M., Santoro, N., Zhang, H., Casson, P., Schlaff, W., Coutifaris, C., Brzyski, R., Christman, G., Carr, B. R., McGovern, P. G., Cataldo, N. A., Steinkampf, M. P., Gosman, G. G., Nestler, J. E., Carson, S., Myers, E. E., Eisenberg, E. & Legro, R., May 1 2012, In : Obstetrics and Gynecology. 119, 5, p. 902-908 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Live Birth
Progestins
Ovulation
Clomiphene
27 Citations (Scopus)

High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples

Leach, R. E., Jessmon, P., Coutifaris, C., Kruger, M., Myers, E. R., Ali-Fehmi, R., Carson, S. A., Legro, R., Schlaff, W. D., Carr, B. R., Steinkampf, M. P., Silva, S., Leppert, P. C., Giudice, L., Diamond, M. P. & Armant, D. R., Jan 1 2012, In : Human Reproduction. 27, 3, p. 814-828 15 p.

Research output: Contribution to journalArticle

Biopsy
Infertility
Proteins
Gene Expression Profiling
Biomarkers

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials

Dapuzzo, L., Seitz, F. E., Dodson, W. C., Stetter, C., Kunselman, A. R. & Legro, R. S., Jan 1 2012, In : Obstetrical and Gynecological Survey. 67, 1, p. 32-34 3 p.

Research output: Contribution to journalComment/debate

Infertility
Mothers
21 Citations (Scopus)

Metabolic and cardiovascular genes in polycystic ovary syndrome: A candidate-wide association study (CWAS)

Jones, M. R., Chua, A. K., Mengesha, E. A., Taylor, K. D., Chen, Y. D. I., Li, X., Krauss, R. M., Rotter, J. I., Legro, R., Azziz, R. & Goodarzi, M. O., Mar 10 2012, In : Steroids. 77, 4, p. 317-322 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Medical problems
Polymorphism
Nucleotides
Genes
73 Citations (Scopus)

Obesity and PCOS: Implications for diagnosis and treatment

Legro, R. S., Oct 22 2012, In : Seminars in reproductive medicine. 30, 6, p. 496-506 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Obesity
Phenotype
Weight Loss
Therapeutics
3 Citations (Scopus)

Quo vadis randomized controlled trials in infertility?

Legro, R., Dec 1 2012, In : Fertility and sterility. 98, 6, p. 1350-1351 2 p.

Research output: Contribution to journalEditorial

Journal Impact Factor
Reproductive Medicine
Infertility
Biomedical Research
Randomized Controlled Trials
20 Citations (Scopus)

Relative contributions of oligomenorrhea and hyperandrogenemia to the risk of metabolic syndrome in midlife women

Polotsky, A. J., Allshouse, A., Crawford, S. L., Harlow, S. D., Khalil, N., Santoro, N. & Legro, R., Jun 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 6

Research output: Contribution to journalArticle

Oligomenorrhea
Androgens
Odds Ratio
Confidence Intervals
Logistic Models
110 Citations (Scopus)

Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts

Goodarzi, M. O., Jones, M. R., Li, X., Chua, A. K., Garcia, O. A., Chen, Y. D. I., Krauss, R. M., Rotter, J. I., Ankener, W., Legro, R., Azziz, R., Strauss, J. F., Dunaif, A. & Urbanek, M., Feb 1 2012, In : Journal of medical genetics. 49, 2, p. 90-95 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genome-Wide Association Study
Nucleotide Mapping
LH Receptors
Menstruation
18 Citations (Scopus)

Reproductive impact of polycystic ovary syndrome

Usadi, R. S. & Legro, R., Dec 1 2012, In : Current Opinion in Endocrinology, Diabetes and Obesity. 19, 6, p. 505-511 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Clomiphene
Live Birth
letrozole
Ovulation Induction
9 Citations (Scopus)

Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility

Jones, M. R., Chazenbalk, G., Xu, N., Chua, A. K., Eigler, T., Mengesha, E., Chen, Y. H., Lee, J. M., Pall, M., Li, X., Chen, Y. D. I., Taylor, K. D., Mathur, R., Krauss, R. M., Rotter, J. I., Legro, R., Azziz, R. & Goodarzi, M. O., Sep 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 9

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Adipose Tissue
Genes
Gene expression
Tissue

Superovulation and multiple birth: In search of kryptonite

Legro, R., Jan 1 2012, In : Fertility and sterility. 97, 4, p. 793-794 2 p.

Research output: Contribution to journalArticle

Superovulation
Multiple Birth Offspring
Multiple Pregnancy
Ovulation Induction
42 Citations (Scopus)

The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: Rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome

Legro, R., Kunselman, A., Brzyski, R. G., Casson, P. R., Diamond, M. P., Schlaff, W. D., Christman, G. M., Coutifaris, C., Taylor, H. S., Eisenberg, E., Santoro, N. & Zhang, H., May 1 2012, In : Contemporary Clinical Trials. 33, 3, p. 470-481 12 p.

Research output: Contribution to journalArticle

letrozole
Clomiphene
Polycystic Ovary Syndrome
Infertility
Pregnancy
5 Citations (Scopus)

Turner syndrome: New insights into an old disorder

Legro, R., Jan 1 2012, In : Fertility and Sterility. 98, 4, p. 773-774 2 p.

Research output: Contribution to journalArticle

Turner Syndrome
Women's Health
Ethics
Growth Hormone
Reproduction
2 Citations (Scopus)
Blood Pressure Monitors
Pregnancy Induced Hypertension
Heart Rate
Blood Pressure
Arterial Pressure
2011
2 Citations (Scopus)

Barriers to conducting clinical research in reproductive medicine: United States of America

Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 4, p. 817-819 3 p.

Research output: Contribution to journalArticle

Reproductive Medicine
National Institutes of Health (U.S.)
Research
8 Citations (Scopus)
Brachial Artery
Polycystic Ovary Syndrome
Hyperemia
LDL Cholesterol
Fasting
14 Citations (Scopus)

Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome

Dmitrovic, R., Katcher, H. I., Kunselman, A. & Legro, R., Oct 1 2011, In : Obstetrics and Gynecology. 118, 4, p. 878-885 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Glucose
Pregnancy
Glucose Tolerance Test
Gestational Diabetes
22 Citations (Scopus)

Current perspectives of insulin resistance and polycystic ovary syndrome

Pauli, J., Raja-Khan, N., Wu, X. & Legro, R., Dec 1 2011, In : Diabetic Medicine. 28, 12, p. 1445-1454 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin Resistance
Cardiovascular Diseases
Metformin
Life Style
31 Citations (Scopus)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Polycystic Ovary Syndrome
Androgens
Blood Vessels
Randomized Controlled Trials
22 Citations (Scopus)

Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: A pilot randomized double-blind study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Lee, P., Williams, N., Coney, P. & Legro, R., Jun 30 2011, In : Fertility and sterility. 95, 8

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Double-Blind Method
Life Style
Hyperandrogenism
8 Citations (Scopus)

Establishing a biologic specimens repository for reproductive clinical trials: Technical aspects

Krawetz, S. A., Casson, P. R., Diamond, M. P., Zhang, H., Legro, R., Schlaff, W. D., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Oct 1 2011, In : Systems Biology in Reproductive Medicine. 57, 5, p. 222-227 6 p.

Research output: Contribution to journalArticle

Reproductive Medicine
Clinical Trials
National Institute of Child Health and Human Development (U.S.)
Research Personnel
Population
27 Citations (Scopus)

Estimating rates of multiple gestation pregnancies: Sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial

Diamond, M. P., Mitwally, M., Casper, R., Ager, J., Legro, R., Brzyski, R., Casson, P., Eisenberg, E. & Zhang, H., Nov 1 2011, In : Contemporary Clinical Trials. 32, 6, p. 902-908 7 p.

Research output: Contribution to journalArticle

Multiple Pregnancy
Ovulation Induction
Sample Size
Infertility
Pregnancy
16 Citations (Scopus)

Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome

Taylor, M. C., Reema Kar, A., Kunselman, A., Stetter, C. M., Dunaif, A. & Legro, R., Jan 1 2011, In : Human Reproduction. 26, 8, p. 2226-2231 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Fathers
Cardiovascular Diseases
Mothers
Nutrition Surveys
65 Citations (Scopus)

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome

Ewens, K. G., Jones, M. R., Ankener, W., Stewart, D. R., Urbanek, M., Dunaif, A., Legro, R. S., Chua, A., Azziz, R., Spielman, R. S., Goodarzi, M. O. & Strauss, J. F., Feb 3 2011, In : PloS one. 6, 1, e16390.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Polycystic Ovary Syndrome
obesity
Obesity
Genes
9 Citations (Scopus)

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome

Jones, M. R., Chua, A., Chen, Y. D. I., Li, X., Krauss, R. M., Rotter, J. I., Legro, R. S., Azziz, R. & Goodarzi, M. O., May 23 2011, In : PloS one. 6, 5, e20120.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Polycystic Ovary Syndrome
Polymorphism
Nucleotides
Genes
12 Citations (Scopus)

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials

Dapuzzo, L., Seitz, F. E., Dodson, W., Stetter, C., Kunselman, A. & Legro, R., Jun 30 2011, In : Fertility and sterility. 95, 8, p. 2527-2530 4 p.

Research output: Contribution to journalArticle

Infertility
Mothers
Pregnancy Outcome
Counseling
Odds Ratio
8 Citations (Scopus)

Increasing burden of institutional review in multicenter clinical trials of infertility: The Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies

Schlaff, W. D., Zhang, H., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Barnhart, K. T., Trussell, J. C., Krawetz, S. A., Snyder, P. J., Ohl, D., Santoro, N., Eisenberg, E., Huang, H. & Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 1, p. 15-18 4 p.

Research output: Contribution to journalArticle

Reproductive Medicine
Polycystic Ovary Syndrome
Research Ethics Committees
Infertility
Multicenter Studies
5 Citations (Scopus)

Metformin and/or clomiphene do not adversely affect liver or renal function in women with polycystic ovary syndrome

Aubuchon, M., Kunselman, A., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R. & Legro, R., Oct 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 10

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Metformin
Liver
Kidney
2 Citations (Scopus)

Metformin as adjuvant therapy to IVF in women with PCOS: When is intention-to-treat unintentional?

Legro, R., Jan 1 2011, In : Human Reproduction. 26, 8, p. 2043-2044 2 p.

Research output: Contribution to journalComment/debate

Female Infertility
Polycystic Ovary Syndrome
Metformin
Pregnancy
Therapeutics
93 Citations (Scopus)

PCOS Forum: Research in polycystic ovary syndrome today and tomorrow

Pasquali, R., Stener-Victorin, E., Yildiz, B. O., Duleba, A. J., Hoeger, K., Mason, H., Homburg, R., Hickey, T., Franks, S., Tapanainen, J. S., Balen, A., Abbott, D. H., Diamanti-Kandarakis, E. & Legro, R., Apr 1 2011, In : Clinical Endocrinology. 74, 4, p. 424-433 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Research
Androgens
Insulin Resistance
Endocrine Disruptors
9 Citations (Scopus)

Polycystic ovary syndrome: Current infertility management

Aubuchon, M. & Legro, R., Dec 1 2011, In : Clinical obstetrics and gynecology. 54, 4, p. 675-684 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Therapeutics
36 Citations (Scopus)

Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome

Wickham, E. P., Ewens, K. G., Legro, R. S., Dunaif, A., Nestler, J. E. & Strauss, J. F., Apr 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 4, p. E719-E727

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
Genes
6 Citations (Scopus)

Proactively establishing a biologic specimens repository for large clinical trials: An idea whose time has come

Casson, P. R., Krawetz, S. A., Diamond, M. P., Zhang, H., Legro, R., Schlaff, W. D., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Oct 1 2011, In : Systems Biology in Reproductive Medicine. 57, 5, p. 217-221 5 p.

Research output: Contribution to journalArticle

Research Personnel
Clinical Trials
Information Dissemination
Information Storage and Retrieval
Confidentiality
13 Citations (Scopus)

Racial influence on the polycystic ovary syndrome phenotype: A black and white case-control study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Williams, N., Coney, P. & Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 1

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Case-Control Studies
Phenotype
Confidence Intervals
hydroquinone