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Research Output 1992 2019

2009
48 Citations (Scopus)

Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2

Biyasheva, A., Legro, R. S., Dunaif, A. & Urbanek, M., Jul 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2617-2625 9 p.

Research output: Contribution to journalArticle

T Cell Transcription Factor 1
Glucose Intolerance
Polycystic Ovary Syndrome
Medical problems
Type 2 Diabetes Mellitus
2 Citations (Scopus)

Heirarchical Clustering and beyond in PCOS Endometrium: Brave new world

Legro, R. & McAllister, J., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1084-1085 2 p.

Research output: Contribution to journalEditorial

Endometrium
Cluster Analysis
42 Citations (Scopus)

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity

Coviello, A. D., Sam, S., Legro, R. & Dunaif, A., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 11, p. 4361-4366 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Nutrition
Testosterone
Obesity
Health
12 Citations (Scopus)

Insulin resistance in women's health: Why it matters and how to identify it

Legro, R. S., Aug 1 2009, In : Current Opinion in Obstetrics and Gynecology. 21, 4, p. 301-305 5 p.

Research output: Contribution to journalReview article

Women's Health
Insulin Resistance
Phenotype
Gestational Diabetes
Pregnancy Complications
18 Citations (Scopus)

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women

Chen, C., Wickenheisser, J., Ewens, K. G., Ankener, W., Legro, R., Dunaif, A., McAllister, J., Spielman, R. S. & Strauss, J. F., Jul 30 2009, In : Molecular Human Reproduction. 15, 8, p. 459-469 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Single Nucleotide Polymorphism
Cyclic AMP
Theca Cells
2 Citations (Scopus)

Polycystic ovary syndrome and cardiovascular disease risk

Legro, R., Dec 1 2009, In : Current Cardiovascular Risk Reports. 3, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Cardiovascular Diseases
Hyperinsulinism
Dyslipidemias
Menopause
39 Citations (Scopus)

Predictors of pregnancy in women with polycystic ovary syndrome

Rausch, M. E., Legro, R., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Giudice, L. C., Leppert, P. C., Myers, E. R. & Coutifaris, C., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3458-3466 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Live Birth
Ovulation
Pregnancy
History

Reply of the Authors: Criteria for the polycystic ovary syndrome

Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R., Norman, R. J., Taylor, A. E. & Witchel, S. F., Jul 1 2009, In : Fertility and sterility. 92, 1

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
1014 Citations (Scopus)

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R. S., Norman, R. J., Taylor, A. E. & Witchel, S. F., Feb 1 2009, In : Fertility and sterility. 91, 2, p. 456-488 33 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Advisory Committees
Androgens
Hyperandrogenism
Consensus
12 Citations (Scopus)

The role of genetic variation in the lamin A/C gene in the etiology of polycystic ovary syndrome

Urbanek, M., Nampiaparampil, G., D'Souza, J., Sefton, E., Ackerman, C., Legro, R. & Dunaif, A., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2665-2669 5 p.

Research output: Contribution to journalArticle

Lamin Type A
Polycystic Ovary Syndrome
Lamins
Genes
Association reactions
2010
40 Citations (Scopus)
Polycystic Ovary Syndrome
Gestational Age
Phenotype
Health
Population
30 Citations (Scopus)

A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome

Raja-Khan, N., Kunselman, A., Demers, L., Ewens, K. G., Spielman, R. S. & Legro, R., Dec 1 2010, In : Fertility and sterility. 94, 7, p. 2916-2919 4 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Transforming Growth Factors
Alleles
Genes
Ovary
6 Citations (Scopus)

Body mass index and intercourse compliance

Pagidas, K., Carson, S. A., McGovern, P. G., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Steinkampf, M. P., Cataldo, N. A., Nestler, J. E., Gosman, G. & Giudice, L. C., Sep 1 2010, In : Fertility and sterility. 94, 4, p. 1447-1450 4 p.

Research output: Contribution to journalArticle

Compliance
Body Mass Index
Polycystic Ovary Syndrome
Reproductive Medicine
Pregnancy
19 Citations (Scopus)

Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome

Zhang, H., Legro, R. S., Zhang, J., Zhang, L., Chen, X., Huang, H., Casson, P. R., Schlaff, W. D., Diamond, M. P., Krawetz, S. A., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Oct 2010, In : Human Reproduction. 25, 10, p. 2612-2621 10 p.

Research output: Contribution to journalArticle

Decision Trees
Clomiphene
Polycystic Ovary Syndrome
Ovulation
Metformin
54 Citations (Scopus)

Effect of air quality on assisted human reproduction

Legro, R. S., Sauer, M. V., Mottla, G. L., Richter, K. S., Li, X., Dodson, W. C. & Liao, D., May 2010, In : Human Reproduction. 25, 5, p. 1317-1324 8 p.

Research output: Contribution to journalArticle

Live Birth
Fertilization in Vitro
Reproduction
Air
Odds Ratio
3 Citations (Scopus)

Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms

Trussell, J. C., Kunselman, A. & Legro, R., Feb 1 2010, In : Fertility and sterility. 93, 3, p. 837-842 6 p.

Research output: Contribution to journalArticle

Lower Urinary Tract Symptoms
Erectile Dysfunction
Epinephrine
Insulin Resistance
Glucose Tolerance Test
33 Citations (Scopus)

Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years

Williams, N., Reed, J. L., Leidy, H. J., Legro, R. & De Souza, M. J., Jan 1 2010, In : Human Reproduction. 25, 9, p. 2328-2339 12 p.

Research output: Contribution to journalArticle

Progesterone
Estrogens
Exercise
Caloric Restriction
Steroids
89 Citations (Scopus)

Family-based analysis of candidate genes for polycystic ovary syndrome

Ewens, K. G., Stewart, D. R., Ankener, W., Urbanek, M., McAllister, J. M., Baig, K. M., Parker, S. C. J., Margulies, E. H., Legro, R. S., Dunaif, A., Strauss, J. F. & Spielman, R. S., May 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2306-2315 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genetic Association Studies
Polymorphism
Nucleotides
Genes

Family-based analysis of candidate genes for polycystic ovary syndrome

Ewens, K. G., Stewart, D. R., Ankener, W., Urbanek, M., McAllister, J., Chen, C., Baig, K. M., Parker, S. C. J., Margulies, E. H., Legro, R., Dunaif, A., Strauss, J. F. & Spielman, R. S., Sep 1 2010, In : Obstetrical and Gynecological Survey. 65, 9, p. 571-572 2 p.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial

Pagidas, K., Carson, S. A., McGovern, P. G., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Steinkampf, M. P., Cataldo, N. A., Nestler, J. E., Gosman, G. & Giudice, L. C., Sep 1 2010, In : Fertility and sterility. 94, 4, p. 1444-1446 3 p.

Research output: Contribution to journalArticle

National Institute of Child Health and Human Development (U.S.)
Reproductive Medicine
Polycystic Ovary Syndrome
Ovulation
Compliance
10 Citations (Scopus)

Metformin during pregnancy in polycystic ovary syndrome: Another vitamin bites the dust

Legro, R., Jan 1 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5199-5202 4 p.

Research output: Contribution to journalEditorial

Metformin
Vitamins
Dust
16 Citations (Scopus)

Peripubertal estrogen levels and physical activity affect femur geometry in young adult women

Devlin, M. J., Stetter, C. M., Lin, H. M., Beck, T. J., Legro, R., Petit, M. A., Lieberman, D. E. & Lloyd, T., Apr 1 2010, In : Osteoporosis International. 21, 4, p. 609-617 9 p.

Research output: Contribution to journalArticle

Femur
Young Adult
Estrogens
Exercise
Menarche

Predictors of pregnancy in women with polycystic ovary syndrome

Rausch, M. E., Legro, R., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Giudice, L. C., Leppert, P. C., Myers, E. R. & Coutifaris, C., Jan 1 2010, In : Obstetrical and Gynecological Survey. 65, 1, p. 30-32 3 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Pregnancy

The case against the routine use of metformin in patients with PCOS undergoing ART

Legro, R., Jan 1 2010, In : Middle East Fertility Society Journal. 15, 4, 1 p.

Research output: Contribution to journalComment/debate

Metformin
1 Citation (Scopus)

The current status for metformin use in reproductive medicine

Legro, R., Dec 1 2010, Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice. Springer New York, p. 183-189 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reproductive Medicine
Metformin
Infertility
Clomiphene
Pregnancy Complications

The role of insulin–sensitising drugs in the treatment of polycystic ovary syndrome

Legro, R., Jan 1 2010, Current Management of Polycystic Ovary Syndrome. Cambridge University Press, p. 173-184 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polycystic Ovary Syndrome
Insulin
Pharmaceutical Preparations
rosiglitazone
Metformin
121 Citations (Scopus)

Total testosterone assays in women with polycystic ovary syndrome: Precision and correlation with hirsutism

Legro, R. S., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Trussell, J. C., Krawetz, S. A., Snyder, P. J., Ohl, D., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R., Santoro, N. & 3 others, Eisenberg, E., Zhang, M. & Zhang, H., Dec 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5305-5313 9 p.

Research output: Contribution to journalArticle

Hirsutism
Polycystic Ovary Syndrome
Liquid chromatography
Liquid Chromatography
Mass spectrometry
2011
2 Citations (Scopus)

Barriers to conducting clinical research in reproductive medicine: United States of America

Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 4, p. 817-819 3 p.

Research output: Contribution to journalArticle

Reproductive Medicine
National Institutes of Health (U.S.)
Research
8 Citations (Scopus)
Brachial Artery
Polycystic Ovary Syndrome
Hyperemia
LDL Cholesterol
Fasting
14 Citations (Scopus)

Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome

Dmitrovic, R., Katcher, H. I., Kunselman, A. & Legro, R., Oct 1 2011, In : Obstetrics and Gynecology. 118, 4, p. 878-885 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Glucose
Pregnancy
Glucose Tolerance Test
Gestational Diabetes
22 Citations (Scopus)

Current perspectives of insulin resistance and polycystic ovary syndrome

Pauli, J., Raja-Khan, N., Wu, X. & Legro, R., Dec 1 2011, In : Diabetic Medicine. 28, 12, p. 1445-1454 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin Resistance
Cardiovascular Diseases
Metformin
Life Style
32 Citations (Scopus)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Polycystic Ovary Syndrome
Androgens
Blood Vessels
Randomized Controlled Trials
22 Citations (Scopus)

Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: A pilot randomized double-blind study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Lee, P., Williams, N., Coney, P. & Legro, R., Jun 30 2011, In : Fertility and sterility. 95, 8

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Double-Blind Method
Life Style
Hyperandrogenism
8 Citations (Scopus)

Establishing a biologic specimens repository for reproductive clinical trials: Technical aspects

Krawetz, S. A., Casson, P. R., Diamond, M. P., Zhang, H., Legro, R., Schlaff, W. D., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Oct 1 2011, In : Systems Biology in Reproductive Medicine. 57, 5, p. 222-227 6 p.

Research output: Contribution to journalArticle

Reproductive Medicine
Clinical Trials
National Institute of Child Health and Human Development (U.S.)
Research Personnel
Population
27 Citations (Scopus)

Estimating rates of multiple gestation pregnancies: Sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial

Diamond, M. P., Mitwally, M., Casper, R., Ager, J., Legro, R., Brzyski, R., Casson, P., Eisenberg, E. & Zhang, H., Nov 1 2011, In : Contemporary Clinical Trials. 32, 6, p. 902-908 7 p.

Research output: Contribution to journalArticle

Multiple Pregnancy
Ovulation Induction
Sample Size
Infertility
Pregnancy
16 Citations (Scopus)

Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome

Taylor, M. C., Reema Kar, A., Kunselman, A., Stetter, C. M., Dunaif, A. & Legro, R., Jan 1 2011, In : Human Reproduction. 26, 8, p. 2226-2231 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Fathers
Cardiovascular Diseases
Mothers
Nutrition Surveys
65 Citations (Scopus)

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome

Ewens, K. G., Jones, M. R., Ankener, W., Stewart, D. R., Urbanek, M., Dunaif, A., Legro, R. S., Chua, A., Azziz, R., Spielman, R. S., Goodarzi, M. O. & Strauss, J. F., Feb 3 2011, In : PloS one. 6, 1, e16390.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Polycystic Ovary Syndrome
obesity
Obesity
Genes
10 Citations (Scopus)

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome

Jones, M. R., Chua, A., Chen, Y. D. I., Li, X., Krauss, R. M., Rotter, J. I., Legro, R. S., Azziz, R. & Goodarzi, M. O., May 23 2011, In : PloS one. 6, 5, e20120.

Research output: Contribution to journalArticle

polycystic ovary syndrome
Polycystic Ovary Syndrome
Polymorphism
Nucleotides
Genes
12 Citations (Scopus)

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials

Dapuzzo, L., Seitz, F. E., Dodson, W., Stetter, C., Kunselman, A. & Legro, R., Jun 30 2011, In : Fertility and sterility. 95, 8, p. 2527-2530 4 p.

Research output: Contribution to journalArticle

Infertility
Mothers
Pregnancy Outcome
Counseling
Odds Ratio
8 Citations (Scopus)

Increasing burden of institutional review in multicenter clinical trials of infertility: The Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies

Schlaff, W. D., Zhang, H., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Barnhart, K. T., Trussell, J. C., Krawetz, S. A., Snyder, P. J., Ohl, D., Santoro, N., Eisenberg, E., Huang, H. & Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 1, p. 15-18 4 p.

Research output: Contribution to journalArticle

Reproductive Medicine
Polycystic Ovary Syndrome
Research Ethics Committees
Infertility
Multicenter Studies
5 Citations (Scopus)

Metformin and/or clomiphene do not adversely affect liver or renal function in women with polycystic ovary syndrome

Aubuchon, M., Kunselman, A., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R. & Legro, R., Oct 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 10

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Metformin
Liver
Kidney
2 Citations (Scopus)

Metformin as adjuvant therapy to IVF in women with PCOS: When is intention-to-treat unintentional?

Legro, R., Jan 1 2011, In : Human Reproduction. 26, 8, p. 2043-2044 2 p.

Research output: Contribution to journalComment/debate

Female Infertility
Polycystic Ovary Syndrome
Metformin
Pregnancy
Therapeutics
94 Citations (Scopus)

PCOS Forum: Research in polycystic ovary syndrome today and tomorrow

Pasquali, R., Stener-Victorin, E., Yildiz, B. O., Duleba, A. J., Hoeger, K., Mason, H., Homburg, R., Hickey, T., Franks, S., Tapanainen, J. S., Balen, A., Abbott, D. H., Diamanti-Kandarakis, E. & Legro, R., Apr 1 2011, In : Clinical Endocrinology. 74, 4, p. 424-433 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Research
Androgens
Insulin Resistance
Endocrine Disruptors
9 Citations (Scopus)

Polycystic ovary syndrome: Current infertility management

Aubuchon, M. & Legro, R., Dec 1 2011, In : Clinical obstetrics and gynecology. 54, 4, p. 675-684 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Therapeutics
36 Citations (Scopus)

Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome

Wickham, E. P., Ewens, K. G., Legro, R. S., Dunaif, A., Nestler, J. E. & Strauss, J. F., Apr 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 4, p. E719-E727

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Polymorphism
Single Nucleotide Polymorphism
Nucleotides
Genes
6 Citations (Scopus)

Proactively establishing a biologic specimens repository for large clinical trials: An idea whose time has come

Casson, P. R., Krawetz, S. A., Diamond, M. P., Zhang, H., Legro, R., Schlaff, W. D., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Oct 1 2011, In : Systems Biology in Reproductive Medicine. 57, 5, p. 217-221 5 p.

Research output: Contribution to journalArticle

Research Personnel
Clinical Trials
Information Dissemination
Information Storage and Retrieval
Confidentiality
14 Citations (Scopus)

Racial influence on the polycystic ovary syndrome phenotype: A black and white case-control study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Williams, N., Coney, P. & Legro, R., Jan 1 2011, In : Fertility and sterility. 96, 1

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Case-Control Studies
Phenotype
Confidence Intervals
hydroquinone
12 Citations (Scopus)

Recruitment challenges of a multicenter randomized controlled varicocelectomy trial

Trussell, J. C., Christman, G. M., Ohl, D. A., Legro, R., Krawetz, S. A., Snyder, P. J., Patrizio, P., Polotsky, A. J., Diamond, M. P., Casson, P. R., Coutifaris, C., Barnhart, K., Brzyski, R. G., Schlaff, W. D., Meacham, R., Shin, D., Thomas, T., Zhang, M., Santoro, N., Eisenberg, E. & 1 others, Zhang, H., Jan 1 2011, In : Fertility and sterility. 96, 6, p. 1299-1305 7 p.

Research output: Contribution to journalReview article

Reproductive Medicine
Insemination
Male Infertility
Randomized Controlled Trials
Placebos
66 Citations (Scopus)

The effects of metformin with lifestyle therapy in polycystic ovary syndrome: A randomized double-blind study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Williams, N., Coney, P. & Legro, R., Mar 1 2011, In : Fertility and sterility. 95, 3

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Double-Blind Method
Life Style
Ovulation
42 Citations (Scopus)

The physiological basis of complementary and alternative medicines for polycystic ovary syndrome

Raja-Khan, N., Stener-Victorin, E., Wu, X. & Legro, R. S., Jul 1 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 1, p. E1-E10

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Complementary Therapies
Autonomic Nervous System
Acupuncture
Therapeutics