If you made any changes in Pure, your changes will be visible here soon.

Research Output 1992 2019

2011
12 Citations (Scopus)

Recruitment challenges of a multicenter randomized controlled varicocelectomy trial

Trussell, J. C., Christman, G. M., Ohl, D. A., Legro, R., Krawetz, S. A., Snyder, P. J., Patrizio, P., Polotsky, A. J., Diamond, M. P., Casson, P. R., Coutifaris, C., Barnhart, K., Brzyski, R. G., Schlaff, W. D., Meacham, R., Shin, D., Thomas, T., Zhang, M., Santoro, N., Eisenberg, E. & 1 others, Zhang, H., Jan 1 2011, In : Fertility and sterility. 96, 6, p. 1299-1305 7 p.

Research output: Contribution to journalReview article

Reproductive Medicine
Insemination
Male Infertility
Randomized Controlled Trials
Placebos
66 Citations (Scopus)

The effects of metformin with lifestyle therapy in polycystic ovary syndrome: A randomized double-blind study

Ladson, G., Dodson, W., Sweet, S. D., Archibong, A. E., Kunselman, A., Demers, L., Williams, N., Coney, P. & Legro, R., Mar 1 2011, In : Fertility and sterility. 95, 3

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Double-Blind Method
Life Style
Ovulation
39 Citations (Scopus)

The physiological basis of complementary and alternative medicines for polycystic ovary syndrome

Raja-Khan, N., Stener-Victorin, E., Wu, X. & Legro, R. S., Jul 1 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 1, p. E1-E10

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Complementary Therapies
Autonomic Nervous System
Acupuncture
Therapeutics
24 Citations (Scopus)

Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome

Ewens, K. G., Jones, M. R., Ankener, W., Stewart, D. R., Urbanek, M., Dunaif, A., Legro, R., Chua, A., Azziz, R., Spielman, R. S., Goodarzi, M. O. & Strauss, J. F., Jun 30 2011, In : Fertility and sterility. 95, 8

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
Menstrual Cycle
Siblings
2010
40 Citations (Scopus)
Polycystic Ovary Syndrome
Gestational Age
Phenotype
Health
Population
29 Citations (Scopus)

A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome

Raja-Khan, N., Kunselman, A., Demers, L., Ewens, K. G., Spielman, R. S. & Legro, R., Dec 1 2010, In : Fertility and sterility. 94, 7, p. 2916-2919 4 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Transforming Growth Factors
Alleles
Genes
Ovary
6 Citations (Scopus)

Body mass index and intercourse compliance

Pagidas, K., Carson, S. A., McGovern, P. G., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Steinkampf, M. P., Cataldo, N. A., Nestler, J. E., Gosman, G. & Giudice, L. C., Sep 1 2010, In : Fertility and sterility. 94, 4, p. 1447-1450 4 p.

Research output: Contribution to journalArticle

Compliance
Body Mass Index
Polycystic Ovary Syndrome
Reproductive Medicine
Pregnancy
19 Citations (Scopus)

Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome

Zhang, H., Legro, R., Zhang, J., Zhang, L., Chen, X., Huang, H., Casson, P. R., Schlaff, W. D., Diamond, M. P., Krawetz, S. A., Coutifaris, C., Brzyski, R. G., Christman, G. M., Santoro, N. & Eisenberg, E., Jan 1 2010, In : Human Reproduction. 25, 10, p. 2612-2621 10 p.

Research output: Contribution to journalArticle

Decision Trees
Clomiphene
Polycystic Ovary Syndrome
Ovulation
Metformin
52 Citations (Scopus)

Effect of air quality on assisted human reproduction

Legro, R. S., Sauer, M. V., Mottla, G. L., Richter, K. S., Li, X., Dodson, W. C. & Liao, D., May 2010, In : Human Reproduction. 25, 5, p. 1317-1324 8 p.

Research output: Contribution to journalArticle

Live Birth
Fertilization in Vitro
Reproduction
Air
Odds Ratio
3 Citations (Scopus)

Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms

Trussell, J. C., Kunselman, A. & Legro, R., Feb 1 2010, In : Fertility and sterility. 93, 3, p. 837-842 6 p.

Research output: Contribution to journalArticle

Lower Urinary Tract Symptoms
Erectile Dysfunction
Epinephrine
Insulin Resistance
Glucose Tolerance Test
33 Citations (Scopus)

Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years

Williams, N., Reed, J. L., Leidy, H. J., Legro, R. & De Souza, M. J., Jan 1 2010, In : Human Reproduction. 25, 9, p. 2328-2339 12 p.

Research output: Contribution to journalArticle

Progesterone
Estrogens
Exercise
Caloric Restriction
Steroids

Family-based analysis of candidate genes for polycystic ovary syndrome

Ewens, K. G., Stewart, D. R., Ankener, W., Urbanek, M., McAllister, J., Chen, C., Baig, K. M., Parker, S. C. J., Margulies, E. H., Legro, R., Dunaif, A., Strauss, J. F. & Spielman, R. S., Sep 1 2010, In : Obstetrical and Gynecological Survey. 65, 9, p. 571-572 2 p.

Research output: Contribution to journalComment/debate

88 Citations (Scopus)

Family-based analysis of candidate genes for polycystic ovary syndrome

Ewens, K. G., Stewart, D. R., Ankener, W., Urbanek, M., McAllister, J. M., Baig, K. M., Parker, S. C. J., Margulies, E. H., Legro, R. S., Dunaif, A., Strauss, J. F. & Spielman, R. S., May 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2306-2315 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genetic Association Studies
Polymorphism
Nucleotides
Genes
5 Citations (Scopus)

Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial

Pagidas, K., Carson, S. A., McGovern, P. G., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Steinkampf, M. P., Cataldo, N. A., Nestler, J. E., Gosman, G. & Giudice, L. C., Sep 1 2010, In : Fertility and sterility. 94, 4, p. 1444-1446 3 p.

Research output: Contribution to journalArticle

National Institute of Child Health and Human Development (U.S.)
Reproductive Medicine
Polycystic Ovary Syndrome
Ovulation
Compliance
10 Citations (Scopus)

Metformin during pregnancy in polycystic ovary syndrome: Another vitamin bites the dust

Legro, R., Jan 1 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5199-5202 4 p.

Research output: Contribution to journalEditorial

Metformin
Vitamins
Dust
16 Citations (Scopus)

Peripubertal estrogen levels and physical activity affect femur geometry in young adult women

Devlin, M. J., Stetter, C. M., Lin, H. M., Beck, T. J., Legro, R., Petit, M. A., Lieberman, D. E. & Lloyd, T., Apr 1 2010, In : Osteoporosis International. 21, 4, p. 609-617 9 p.

Research output: Contribution to journalArticle

Femur
Young Adult
Estrogens
Exercise
Menarche

Predictors of pregnancy in women with polycystic ovary syndrome

Rausch, M. E., Legro, R., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Giudice, L. C., Leppert, P. C., Myers, E. R. & Coutifaris, C., Jan 1 2010, In : Obstetrical and Gynecological Survey. 65, 1, p. 30-32 3 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Pregnancy

The case against the routine use of metformin in patients with PCOS undergoing ART

Legro, R., Jan 1 2010, In : Middle East Fertility Society Journal. 15, 4, 1 p.

Research output: Contribution to journalComment/debate

Metformin
1 Citation (Scopus)

The current status for metformin use in reproductive medicine

Legro, R., Dec 1 2010, Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice. Springer New York, p. 183-189 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reproductive Medicine
Metformin
Infertility
Clomiphene
Pregnancy Complications

The role of insulin–sensitising drugs in the treatment of polycystic ovary syndrome

Legro, R., Jan 1 2010, Current Management of Polycystic Ovary Syndrome. Cambridge University Press, p. 173-184 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Polycystic Ovary Syndrome
Insulin
Pharmaceutical Preparations
rosiglitazone
Metformin
119 Citations (Scopus)

Total testosterone assays in women with polycystic ovary syndrome: Precision and correlation with hirsutism

Legro, R., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Trussell, J. C., Krawetz, S. A., Snyder, P. J., Ohl, D., Carson, S. A., Steinkampf, M. P., Carr, B. R., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Myers, E. R., Santoro, N. & 3 others, Eisenberg, E., Zhang, M. & Zhang, H., Jan 1 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5305-5313 9 p.

Research output: Contribution to journalArticle

Hirsutism
Polycystic Ovary Syndrome
Liquid chromatography
Liquid Chromatography
Mass spectrometry
2009
16 Citations (Scopus)
Polycystic Ovary Syndrome
Meals
Fats
Hydrocortisone
Carbohydrates
48 Citations (Scopus)

Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2

Biyasheva, A., Legro, R., Dunaif, A. & Urbanek, M., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2617-2625 9 p.

Research output: Contribution to journalArticle

T Cell Transcription Factor 1
Glucose Intolerance
Polycystic Ovary Syndrome
Medical problems
Type 2 Diabetes Mellitus
2 Citations (Scopus)

Heirarchical Clustering and beyond in PCOS Endometrium: Brave new world

Legro, R. & McAllister, J., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1084-1085 2 p.

Research output: Contribution to journalEditorial

Endometrium
Cluster Analysis
41 Citations (Scopus)

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity

Coviello, A. D., Sam, S., Legro, R. & Dunaif, A., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 11, p. 4361-4366 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Nutrition
Testosterone
Obesity
Health
12 Citations (Scopus)

Insulin resistance in women's health: Why it matters and how to identify it

Legro, R., Aug 1 2009, In : Current Opinion in Obstetrics and Gynecology. 21, 4, p. 301-305 5 p.

Research output: Contribution to journalReview article

Women's Health
Insulin Resistance
Phenotype
Gestational Diabetes
Pregnancy Complications
16 Citations (Scopus)

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women

Chen, C., Wickenheisser, J., Ewens, K. G., Ankener, W., Legro, R., Dunaif, A., McAllister, J., Spielman, R. S. & Strauss, J. F., Jul 30 2009, In : Molecular Human Reproduction. 15, 8, p. 459-469 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Single Nucleotide Polymorphism
Cyclic AMP
Theca Cells
2 Citations (Scopus)

Polycystic ovary syndrome and cardiovascular disease risk

Legro, R., Dec 1 2009, In : Current Cardiovascular Risk Reports. 3, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Cardiovascular Diseases
Hyperinsulinism
Dyslipidemias
Menopause
38 Citations (Scopus)

Predictors of pregnancy in women with polycystic ovary syndrome

Rausch, M. E., Legro, R., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Giudice, L. C., Leppert, P. C., Myers, E. R. & Coutifaris, C., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3458-3466 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Live Birth
Ovulation
Pregnancy
History

Reply of the Authors: Criteria for the polycystic ovary syndrome

Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R., Norman, R. J., Taylor, A. E. & Witchel, S. F., Jul 1 2009, In : Fertility and sterility. 92, 1

Research output: Contribution to journalLetter

Polycystic Ovary Syndrome
1007 Citations (Scopus)

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R., Norman, R. J., Taylor, A. E. & Witchel, S. F., Feb 1 2009, In : Fertility and sterility. 91, 2, p. 456-488 33 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Advisory Committees
Androgens
Hyperandrogenism
Consensus
12 Citations (Scopus)

The role of genetic variation in the lamin A/C gene in the etiology of polycystic ovary syndrome

Urbanek, M., Nampiaparampil, G., D'Souza, J., Sefton, E., Ackerman, C., Legro, R. & Dunaif, A., Jan 1 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2665-2669 5 p.

Research output: Contribution to journalArticle

Lamin Type A
Polycystic Ovary Syndrome
Lamins
Genes
Association reactions
2008
9 Citations (Scopus)
Reproduction
Clinical Trials
African Americans
Volunteers
Research
339 Citations (Scopus)

Consensus on infertility treatment related to polycystic ovary syndrome

Tarlatzis, B. C., Fauser, B. C. J. M., Legro, R., Norman, R. J., Hoeger, K., Pasquali, R., Franks, S., Messinis, I. E., Casper, R. F., Homburg, R., Lobo, R., Rebar, R. W., Fleming, R., Carr, B. R., Bouchard, P., Chang, J., Hugues, J. N., Azziz, R., Kolibianakis, E. M., Griesinger, G. & 11 others, Diedrich, K., Balen, A., Farquhar, C., Devroey, P., Ho, P. C., Collins, J., Goulis, D. G., Eijkemans, R., Crosignani, P. G., DeCherney, A. & Van Steirteghem, A., Jan 1 2008, In : Human Reproduction. 23, 3, p. 462-477 16 p.

Research output: Contribution to journalArticle

Ovulation Induction
Polycystic Ovary Syndrome
Infertility
Consensus
Clomiphene
2 Citations (Scopus)

Consensus on infertility treatment related to polycystic ovary syndrome (Human Reproduction (2007) 23, (462))

Tarlatzis, B. C., Fauser, B. C. J. M., Legro, R., Norman, R. J., Hoeger, K., Pasquali, R., Franks, S., Messinis, I. E., Casper, R. F., Homburg, R., Lobo, R., Rebar, R. W., Fleming, R., Carr, B. R., Bouchard, P., Chang, J., Hugues, J. N., Azziz, R., Kolibianakis, E. M., Griesinger, G. & 11 others, Diedrich, K., Balen, A., Farquhar, C., Devroey, P., Ho, P. C., Collins, J., Goulis, D. G., Eijkemans, R., Crosignani, P. G., DeCherney, A. & Van Steirteghem, A., Jan 1 2008, In : Human Reproduction. 23, 6, 1 p.

Research output: Contribution to journalComment/debate

Polycystic Ovary Syndrome
Infertility
Reproduction
126 Citations (Scopus)

Diminished paternity and gonadal function with increasing obesity in men

Pauli, E., Legro, R., Demers, L., Kunselman, A., Dodson, W. & Lee, P., Aug 1 2008, In : Fertility and sterility. 90, 2, p. 346-351 6 p.

Research output: Contribution to journalArticle

Paternity
Obesity
Skinfold Thickness
Body Mass Index
Semen Analysis
5 Citations (Scopus)

Does polycystic ovary syndrome increase the disparity in metabolic syndrome and cardiovascular-related health for African-American women?

Coney, P. J., Ladson, G., Sweet, S. & Legro, R., Jan 1 2008, In : Seminars in Reproductive Medicine. 26, 1, p. 35-38 4 p.

Research output: Contribution to journalArticle

Metabolic Syndrome X
Polycystic Ovary Syndrome
African Americans
Health
Cardiovascular Diseases
60 Citations (Scopus)

Effects of continuous versus cyclical oral contraception: A randomized controlled trial

Legro, R., Pauli, J., Kunselman, A., Meadows, J. W., Kesner, J. S., Zaino, R. J., Demers, L., Gnatuk, C. & Dodson, W., Jan 1 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 420-429 10 p.

Research output: Contribution to journalArticle

Contraception
Randomized Controlled Trials
Ultrasonics
Ethinyl Estradiol
Hemorrhage
37 Citations (Scopus)

Evidence for pancreatic β-cell dysfunction in brothers of women with polycystic ovary syndrome

Sam, S., Sung, Y. A., Legro, R. & Dunaif, A., Jan 1 2008, In : Metabolism: Clinical and Experimental. 57, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Siblings
Insulin Resistance
Glucose Tolerance Test
Type 2 Diabetes Mellitus
10 Citations (Scopus)

Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome

Cataldo, N. A., Barnhart, H. X., Legro, R., Myers, E. R., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., Coutifaris, C., McGovern, P. G., Gosman, G., Nestler, J. E. & Giudice, L. C., Jan 1 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 8, p. 3124-3127 4 p.

Research output: Contribution to journalArticle

Clomiphene
Polycystic Ovary Syndrome
Metformin
Ovulation
National Institute of Child Health and Human Development (U.S.)
49 Citations (Scopus)
Hyperandrogenism
Polycystic Ovary Syndrome
Hyperinsulinism
Insulin
Puberty

Hyperandrogenism and hyperinsulinism in children of women with polycystic ovary syndrome: A controlled study

Kent, S. C., Gnatuk, C., Kunselman, A., Demers, L., Lee, P. & Legro, R., Oct 1 2008, In : Obstetrical and Gynecological Survey. 63, 10, p. 646-647 2 p.

Research output: Contribution to journalComment/debate

Hyperandrogenism
Polycystic Ovary Syndrome
Hyperinsulinism
8 Citations (Scopus)
Metformin
Oral Contraceptives
Pharmaceutical Preparations
2 Citations (Scopus)

Individualizing infertility therapy with pharmacogenomics: Vanity or vanguard?

Legro, R., Nov 11 2008, In : Pharmacogenomics. 9, 9, p. 1179-1181 3 p.

Research output: Contribution to journalEditorial

Female Infertility
Pharmacogenetics
Infertility
Therapeutics
7 Citations (Scopus)

Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial

McGovern, P. G., Carson, S. A., Barnhart, H. X., Myers, E. R., Legro, R., Diamond, M. P., Carr, B. R., Schlaff, W. D., Coutifaris, C., Cataldo, N. A., Steinkampf, M. P., Nestler, J. E., Gosman, G., Leppert, P. C. & Giudice, L. C., Oct 1 2008, In : Fertility and sterility. 90, 4, p. 1283-1286 4 p.

Research output: Contribution to journalArticle

National Institute of Child Health and Human Development (U.S.)
Reproductive Medicine
Medication Adherence
Polycystic Ovary Syndrome
Metformin
39 Citations (Scopus)

Metabolic phenotype in the brothers of women with polycystic ovary syndrome

Sam, S., Coviello, A. D., Sung, Y. A., Legro, R. & Dunaif, A., Jun 1 2008, In : Diabetes Care. 31, 6, p. 1237-1241 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Siblings
Phenotype
Insulin Resistance
Dyslipidemias

New directions in polycystic ovary syndrome

Legro, R. S., Jan 1 2008, In : Seminars in reproductive medicine. 26, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

Polycystic Ovary Syndrome
Direction compound
79 Citations (Scopus)

Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene

Legro, R., Barnhart, H. X., Schlaff, W. D., Carr, B. R., Diamond, M. P., Carson, S. A., Steinkampf, M. P., Coutifaris, C., McGovern, P. G., Cataldo, N. A., Gosman, G. G., Nestler, J. E., Giudice, L. C., Ewens, K. G., Spielman, R. S., Leppert, P. C. & Myers, E. R., Jan 1 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 792-800 9 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Metformin
Polymorphism
Ovulation
Body Mass Index
Polycystic Ovary Syndrome
Gynecology
Obstetrics
Pregnancy
206 Citations (Scopus)

The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome

Katcher, H. I., Legro, R., Kunselman, A., Gillies, P. J., Demers, L., Bagshaw, D. M. & Kris-Etherton, P. M., Jan 1 2008, In : American Journal of Clinical Nutrition. 87, 1, p. 79-90 12 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Diet
Reducing Diet
Adipose Tissue
Weight Loss