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Research Output 1992 2019

2003
30 Citations (Scopus)

Diagnostic Criteria in Polycystic Ovary Syndrome

Legro, R., Aug 1 2003, In : Seminars in Reproductive Medicine. 21, 3, p. 267-275 9 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Ovulation
Insulin Resistance
Hyperandrogenism
Signs and Symptoms
134 Citations (Scopus)

Difference in body weight between American and Italian women with polycystic ovary syndrome: Influence of the diet

Carmina, E., Legro, R., Stamets, K., Lowell, J. & Lobo, R. A., Jan 1 2003, In : Human Reproduction. 18, 11, p. 2289-2293 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Body Weight
Diet
Italy
Dietary Fats
41 Citations (Scopus)

Minimal Response of Circulating Lipids in Women with Polycystic Ovary Syndrome to Improvement in Insulin Sensitivity with Troglitazone

Legro, R., Azziz, R., Ehrmann, D., Fereshetian, A. G., O'Keefe, M. & Ghazzi, M. N., Nov 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 11, p. 5137-5144 8 p.

Research output: Contribution to journalArticle

troglitazone
Polycystic Ovary Syndrome
Insulin Resistance
Insulin
Lipids
356 Citations (Scopus)

Polycystic ovary syndrome and cardiovascular disease: A premature association?

Legro, R., Jun 1 2003, In : Endocrine Reviews. 24, 3, p. 302-312 11 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Cardiovascular Diseases
Anovulation
Hyperandrogenism
Ovary
64 Citations (Scopus)

Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome

Azziz, R., Ehrmann, D. A., Legro, R., Fereshetian, A. G., O'Keefe, M. & Ghazzi, M. N., Apr 1 2003, In : Fertility and sterility. 79, 4, p. 932-937 6 p.

Research output: Contribution to journalArticle

troglitazone
Polycystic Ovary Syndrome
Androgens
Insulin
Insulin Resistance
30 Citations (Scopus)

Urinary free cortisol increases in adolescent Caucasian females during perimenarche

Legro, R., Lin, H. M., Demers, L. & Lloyd, T., Jan 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 1, p. 215-219 5 p.

Research output: Contribution to journalArticle

Hydrocortisone
Body Surface Area
Longitudinal Studies
Creatinine
63 Citations (Scopus)

Variation in resistin gene promoter not associated with polycystic ovary syndrome

Urbanek, M., Du, Y., Silander, K., Collins, F. S., Steppan, C. M., Strauss, J. F., Dunaif, A., Spielman, R. S. & Legro, R., Jan 1 2003, In : Diabetes. 52, 1, p. 214-217 4 p.

Research output: Contribution to journalArticle

Resistin
Polycystic Ovary Syndrome
Genes
Insulin Resistance
Obesity
2002
13 Citations (Scopus)

Adolescent Caucasian mothers have reduced adult hip bone density

Lloyd, T., Lin, H. M., Eggli, D. F., Dodson, W., Demers, L. & Legro, R., Feb 5 2002, In : Fertility and sterility. 77, 1, p. 136-140 5 p.

Research output: Contribution to journalArticle

Pelvic Bones
Bone Density
Mothers
Pregnancy in Adolescence
Menarche
41 Citations (Scopus)

Detection of insulin resistance and its treatment in adolescents with polycystic ovary syndrome

Legro, R., Dec 1 2002, In : Journal of Pediatric Endocrinology and Metabolism. 15, SUPPL. 5, p. 1367-1378 12 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Adrenarche
Anovulation
Hyperandrogenism
15 Citations (Scopus)

Diabetes prevalence and risk factors in polycystic ovary syndrome

Legro, R., Dec 1 2002, In : Current Opinion in Endocrinology and Diabetes. 9, 6, p. 451-458 8 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Glucose Intolerance
Glucose Tolerance Test
Glucose
Anovulation
116 Citations (Scopus)

Elevated dehydroepiandrosterone sulfate levels as the reproductive phenotype in the brothers of women with polycystic ovary syndrome

Legro, R., Kunselman, A., Demers, L., Wang, S. C., Bentley-Lewis, R. & Dunaif, A., Jan 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 5, p. 2134-2138 5 p.

Research output: Contribution to journalArticle

Dehydroepiandrosterone Sulfate
Polycystic Ovary Syndrome
Siblings
Phenotype
Blood
165 Citations (Scopus)

Insulin resistance in the sisters of women with polycystic ovary syndrome: Association with hyperandrogenemia rather than menstrual irregularity

Legro, R., Bentley-Lewis, R., Driscoll, D., Wang, S. C. & Dunaif, A., Jan 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 5, p. 2128-2133 6 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Siblings
Insulin
Proinsulin
1 Citation (Scopus)

Management and treatment of hirsutism in the elderly woman

Legro, R., Nov 1 2002, In : Annals of Long-Term Care. 10, 11, p. 41-47 7 p.

Research output: Contribution to journalReview article

Hirsutism
Therapeutics
Skin Cream
Eflornithine
Electrolysis
119 Citations (Scopus)

Molecular progress in infertility: Polycystic ovary syndrome

Legro, R. & Strauss, J. F., Jan 1 2002, In : Fertility and Sterility. 78, 3, p. 569-576 8 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Infertility
Genes
Insulin Receptor
Phenotype
31 Citations (Scopus)

Oral contraceptive use by teenage women does not affect body composition

Lloyd, T., Lin, H. M., Matthews, A. E., Bentley, C. M. & Legro, R., Aug 23 2002, In : Obstetrics and Gynecology. 100, 2, p. 235-239 5 p.

Research output: Contribution to journalArticle

Oral Contraceptives
Body Composition
Adipose Tissue
Serum
Cholesterol
28 Citations (Scopus)

Polycystic ovary syndrome: Long term sequelae and management

Legro, R., Apr 1 2002, In : Minerva Ginecologica. 54, 2, p. 97-114 18 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Glucose Intolerance
Insulin
Type 2 Diabetes Mellitus
Insulin Resistance
9 Citations (Scopus)

Polycystic ovary syndrome: The new millenium

Legro, R., Jan 25 2002, In : Molecular and Cellular Endocrinology. 186, 2, p. 219-225 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin
Insulin Resistance
Hyperandrogenism
Gonadotropins
37 Citations (Scopus)

Polycystic ovary syndrome in adolescents.

Kent, S. C. & Legro, R., Jan 1 2002, In : Adolescent medicine (Philadelphia, Pa.). 13, 1

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin
Lipids
Insulin Resistance
Fasting
278 Citations (Scopus)

Screening for abnormal glucose tolerance in adolescents with polycystic ovary syndrome

Palmert, M. R., Gordon, C. M., Kartashov, A. I., Legro, R., Emans, J. J. & Dunaif, A., Jan 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 3, p. 1017-1023 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Screening
Glucose Intolerance
Glucose
Diabetes Mellitus
27 Citations (Scopus)

Self-selected women with polycystic ovary syndrome are reproductively and metabolically abnormal and undertreated

Legro, R., Urbanek, M., Kunselman, A., Leiby, B. E. & Dunaif, A., Jul 15 2002, In : Fertility and sterility. 78, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Fasting
Self-Help Groups
Oligomenorrhea
Insulin
2001
43 Citations (Scopus)

Diabetes prevalence and risk factors in polycystic ovary syndrome

Legro, R., Jan 1 2001, In : Obstetrics and Gynecology Clinics of North America. 28, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Glucose Intolerance
Glucose
Fasting
Type 2 Diabetes Mellitus
56 Citations (Scopus)

Polycystic ovary syndrome: The new millenium

Legro, R., Nov 26 2001, In : Molecular and Cellular Endocrinology. 184, 1-2, p. 87-93 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin
Insulin Resistance
Hyperandrogenism
Gonadotropins
271 Citations (Scopus)

Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: Role of insulin resistance

Vgontzas, A., Legro, R., Bixler, E., Grayev, A., Kales, A. & Chrousos, G. P., Mar 22 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 2, p. 517-520 4 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Obstructive Sleep Apnea
Insulin Resistance
Insulin
Sleep Apnea Syndromes
376 Citations (Scopus)

Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome

Legro, R., Kunselman, A. & Dunaif, A., Dec 1 2001, In : American Journal of Medicine. 111, 8, p. 607-613 7 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Dyslipidemias
LDL Cholesterol
Confidence Intervals
HDL Cholesterol
23 Citations (Scopus)

Role of androgens in the growth of endometrial carcinoma: An in vivo animal model

Legro, R., Kunselman, A., Miller, S. A. & Satyaswaroop, P. G., Jan 1 2001, In : American journal of obstetrics and gynecology. 184, 3, p. 303-308 6 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Androgens
Animal Models
Growth
Estrogens

Spontaneous conception in the presence of stage IIIC endometrioid ovarian cancer

Bennett, R. A., Dodson, W., Olt, G. J., Ahearn, J. & Legro, R., Mar 8 2001, In : Fertility and Sterility. 75, 3, p. 623-624 2 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Endometrioid Carcinoma
Ovulation
Hysterectomy
Laparotomy
258 Citations (Scopus)

The biochemical basis for increased Testosterone production in theca cells propagated from patients with polycystic ovary syndrome

Nelson, V. L., Qin, K. N., Rosenfield, R. L., Wood, J. R., Penning, T. M., Legro, R., Strauss, J. F. & McAllister, J., Jan 1 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 12, p. 5925-5933 9 p.

Research output: Contribution to journalArticle

Theca Cells
Polycystic Ovary Syndrome
Testosterone
Enzyme activity
Granulosa Cells
482 Citations (Scopus)

Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: A multicenter, double blind, placebo-controlled trial

Azziz, R., Ehrmann, D., Legro, R., Whitcomb, R. W., Hanley, R., Fereshetian, A. G., O'Keefe, M. & Ghazzi, M. N., May 7 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 4, p. 1626-1632 7 p.

Research output: Contribution to journalArticle

troglitazone
Hirsutism
Polycystic Ovary Syndrome
Ovulation
Placebos
5 Citations (Scopus)

Troglitazone use in polycystic ovary syndrome [4]

Landman, R. E., Jacobs, T. P., Azziz, R., Ehrmann, D., Legro, R., Whitcomb, R., Hanley, R., Fereshtian, A. G., O'Keefe, M. & Ghazzi, M. N., Nov 12 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 10, p. 5090-5091 2 p.

Research output: Contribution to journalLetter

troglitazone
Chromans
Thiazoles
Thiazolidinediones
Hypoglycemic Agents
2000
79 Citations (Scopus)

Allelic variants of the follistatin gene in polycystic ovary syndrome

Urbanek, M., Wu, X., Vickery, K. R., Kao, L. C., Christenson, L. K., Schneyer, A., Legro, R., Driscoll, D. A., Strauss, J. F., Dunaif, A. & Spielman, R. S., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 12, p. 4455-4461 7 p.

Research output: Contribution to journalArticle

Follistatin
Polycystic Ovary Syndrome
Genes
Genetic Linkage
Fibroblasts
137 Citations (Scopus)

Differential activity of the cytochrome P450 17α-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells

Wickenheisser, J. K., Quinn, P. G., Nelson, V. L., Legro, R., Strauss, J. F. & McAllister, J., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 6, p. 2304-2311 8 p.

Research output: Contribution to journalArticle

Steroid 17-alpha-Hydroxylase
Theca Cells
Polycystic Ovary Syndrome
Regulator Genes
Mixed Function Oxygenases
18 Citations (Scopus)

Is there a male phenotype in polycystic ovary syndrome families?

Legro, R., 2000, In : Journal of Pediatric Endocrinology and Metabolism. 13, SUPPL. 5, p. 1307-1309 3 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Phenotype
Sample Size
Hair
Insulin Resistance
53 Citations (Scopus)

Oral contraceptive use by teenage women does not affect peak bone mass: A longitudinal study

Lloyd, T., Taylor, D. S., Lin, H. M., Matthews, A. E., Eggli, D. F. & Legro, R., Oct 1 2000, In : Fertility and Sterility. 74, 4, p. 734-738 5 p.

Research output: Contribution to journalArticle

Oral Contraceptives
Longitudinal Studies
Bone and Bones
Body Composition
Pelvic Bones
103 Citations (Scopus)

Rapid maturation of the reproductive axis during perimenarche independent of body composition

Legro, R., Lin, H. M., Demers, L. & Lloyd, T., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 3, p. 1021-1025 5 p.

Research output: Contribution to journalArticle

Menarche
Nutrition
Body Composition
Fats
Steroids
37 Citations (Scopus)

Searching for the polycystic ovary syndrome genes

Urbanek, M., Legro, R., Driscoll, D., Strauss, J. F., Dunaif, A. & Spielman, R. S., Dec 13 2000, In : Journal of Pediatric Endocrinology and Metabolism. 13, SUPPL. 5, p. 1311-1313 3 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Siblings
Genes
Chromosomes, Human, Pair 19
Insulin Receptor
61 Citations (Scopus)

The genetics of obesity. Lessons for polycystic ovary syndrome

Legro, R., Jan 1 2000, In : Annals of the New York Academy of Sciences. 900, p. 193-202 10 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Androgens
Obesity
Genes
Defects
13 Citations (Scopus)

The mentor effect in student evaluation

Coulson, C. C., Kunselman, A., Cain, J. & Legro, R., Apr 1 2000, In : Obstetrics and Gynecology. 95, 4, p. 619-622 4 p.

Research output: Contribution to journalArticle

Mentors
Students
Confidence Intervals
Odds Ratio
Financial Management
1999
51 Citations (Scopus)
Polycystic Ovary Syndrome
HDL Lipoproteins
LDL Lipoproteins
Hispanic Americans
Insulin
344 Citations (Scopus)

Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries

Nelson, V. L., Legro, R., Strauss, J. F. & McAllister, J., Jan 1 1999, In : Molecular Endocrinology. 13, 6, p. 946-957 12 p.

Research output: Contribution to journalArticle

Theca Cells
Polycystic Ovary Syndrome
Androgens
Ovary
Phenotype
65 Citations (Scopus)

Bone mineral density and body composition in lean women with polycystic ovary syndrome

Good, C., Tulchinsky, M., Mauger, D., Demers, L. & Legro, R., Jul 1 1999, In : Fertility and Sterility. 72, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Body Composition
Bone Density
Fats
Androgens
2 Citations (Scopus)

Comment on glucose-to-insulin ratio as a measure of insulin sensitivity in women with PCOS [2]

Nagasaka, S., Ishikawa, S. E., Saito, T., Legro, R. & Dunaif, A., Jan 1 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 1, 1 p.

Research output: Contribution to journalLetter

Insulin
Glucose

Fallas reproductivas por mutaciones genicas

Translated title of the contribution: Female reproductive failure due to genetic mutationsLegro, R., 1999, In : Revista Argentina de Endocrinologia y Metabolismo. 36, 3, p. 169-178 10 p.

Research output: Contribution to journalArticle

Protein Isoforms
Mutation
Hormones
Genes
Gonadotropins
3 Citations (Scopus)

Oocyte donors as gynecologic teaching associates

Legro, R., Gnatuk, C., Kunselman, A. & Cain, J., Jan 1 1999, In : Obstetrics and Gynecology. 93, 1, p. 147-150 4 p.

Research output: Contribution to journalArticle

Oocytes
Teaching
Tissue Donors
Students
Gynecological Examination
39 Citations (Scopus)

Polycystic ovary syndrome: Phenotype to genotype

Legro, R., Jan 1 1999, In : Endocrinology and Metabolism Clinics of North America. 28, 2, p. 379-396 18 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Genotype
Phenotype
Pedigree
Cluster Analysis
1374 Citations (Scopus)
Glucose Intolerance
Polycystic Ovary Syndrome
Medical problems
Type 2 Diabetes Mellitus
Prospective Studies
Glucose Intolerance
Polycystic Ovary Syndrome
Type 2 Diabetes Mellitus
12 Citations (Scopus)

Reproductive outcome after sterilization reversal in women of advanced reproductive age

Cohen, M. A., Chang, P. L., Uhler, M., Legro, R., Sauer, M. V. & Lindheim, S. R., Sep 7 1999, In : Journal of Assisted Reproduction and Genetics. 16, 8, p. 402-404 3 p.

Research output: Contribution to journalArticle

Sterilization Reversal
Pregnancy Rate
Tubal Sterilization
Semen Analysis
Ectopic Pregnancy
35 Citations (Scopus)

The proenkephalin gene (PENK) and opioid dependence

Comings, D. E., Blake, H., Dietz, G., Gade-Andavolu, R., Legro, R., Saucier, G., Johnson, P., Verde, R. & MacMurray, J. P., Apr 6 1999, In : NeuroReport. 10, 5, p. 1133-1135 3 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Genes
Substance-Related Disorders
Alleles
Heroin Dependence
388 Citations (Scopus)

Thirty-seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with follistatin

Urbanek, M., Legro, R., Driscoll, D. A., Azziz, R., Ehrmann, D. A., Norman, R. J., Strauss, J. F., Spielman, R. S. & Dunaif, A., Jul 20 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 15, p. 8573-8578 6 p.

Research output: Contribution to journalArticle

Follistatin
Polycystic Ovary Syndrome
Genes
Alleles
Anovulation
1998
622 Citations (Scopus)

A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome

Legro, R., Finegood, D. & Dunaif, A., Nov 10 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 8, p. 2694-2698 5 p.

Research output: Contribution to journalArticle

Polycystic Ovary Syndrome
Insulin Resistance
Fasting
Insulin
Glucose