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Research Output 1992 2019

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Review article
2019

Pharmacology of medications used for ovarian stimulation

Quaas, A. M. & Legro, R. S., Feb 2019, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 33, 1, p. 21-33 13 p.

Research output: Contribution to journalReview article

letrozole
Ovulation Induction
Ovary
Kisspeptins
Pharmacology
2 Citations (Scopus)

The efficiency of single institutional review board review in National Institute of Child Health and Human Development Cooperative Reproductive Medicine Network–initiated clinical trials

for the National Institute of Child Health and Human Development Cooperative Reproductive Medicine Network, Feb 1 2019, In : Clinical Trials. 16, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

National Institute of Child Health and Human Development (U.S.)
Reproductive Medicine
Research Ethics Committees
Clinical Trials
Language
2017
11 Citations (Scopus)

Effects of obesity treatment on female reproduction: results do not match expectations

Legro, R., Apr 1 2017, In : Fertility and sterility. 107, 4, p. 860-867 8 p.

Research output: Contribution to journalReview article

Weight Gain
Reproduction
Weight Loss
Bariatric Surgery
Obesity
2016
3 Citations (Scopus)
Type 2 Diabetes Mellitus
Clinical Trials
Pharmaceutical Preparations
Pregnancy
Fertility
25 Citations (Scopus)

Ovulation induction in polycystic ovary syndrome: Current options

Legro, R., Nov 1 2016, In : Best Practice and Research: Clinical Obstetrics and Gynaecology. 37, p. 152-159 8 p.

Research output: Contribution to journalReview article

Ovulation Induction
Polycystic Ovary Syndrome
Clomiphene
letrozole
Metformin
175 Citations (Scopus)

Polycystic ovary syndrome

Azziz, R., Carmina, E., Chen, Z., Dunaif, A., Laven, J. S. E., Legro, R. S., Lizneva, D., Natterson-Horowtiz, B., Teede, H. J. & Yildiz, B. O., Aug 11 2016, In : Nature Reviews Disease Primers. 2, 16057.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Hyperandrogenism
Androgens
Gestational Diabetes
Pregnancy Complications
8 Citations (Scopus)

Treatment strategies for infertile women with polycystic ovary syndrome

Vitek, W., Hoeger, K. & Legro, R. S., Aug 2016, In : Minerva Ginecologica. 68, 4, p. 450-457 8 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Infertility
Ovulation Induction
Ovulation
Hyperandrogenism
2015
118 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Insulin Resistance
134 Citations (Scopus)
Endocrinology
Polycystic Ovary Syndrome
Practice Guidelines
Androgens
Anovulation
57 Citations (Scopus)

Functional genomics of PCOS: From GWAS to molecular mechanisms

McAllister, J., Legro, R., Modi, B. P. & Strauss, J. F., Mar 1 2015, In : Trends in Endocrinology and Metabolism. 26, 3, p. 118-124 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Genome-Wide Association Study
Genomics
Androgens
Theca Cells
180 Citations (Scopus)

Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome

Dumesic, D. A., Oberfield, S. E., Stener-Victorin, E., Marshall, J. C., Laven, J. S. & Legro, R. S., Jan 1 2015, In : Endocrine Reviews. 36, 5, p. 487-525 39 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Hyperandrogenism
Molecular Biology
Epidemiology
Phenotype
2014
39 Citations (Scopus)

The role of TGF-β in polycystic ovary syndrome

Raja-Khan, N., Urbanek, M., Rodgers, R. J. & Legro, R., Jan 1 2014, In : Reproductive Sciences. 21, 1, p. 20-31 12 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Transforming Growth Factors
Extracellular Matrix
Cardiovascular Abnormalities
Microfibrils
2013

Introduction: Back to the future: Origins of polycystic ovary syndrome

Legro, R., Jan 1 2013, In : Fertility and Sterility. 100, 1, 1 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Pregnancy
41 Citations (Scopus)

Longterm management of Polycystic Ovarian Syndrome (PCOS)

Bates, G. W. & Legro, R., Jul 5 2013, In : Molecular and Cellular Endocrinology. 373, 1-2, p. 91-97 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Metformin
Medical problems
Oral Contraceptives
Risk assessment
24 Citations (Scopus)

Ovulation induction in women with polycystic ovary syndrome

Perales-Puchalt, A. & Legro, R., Jan 1 2013, In : Steroids. 78, 8, p. 767-772 6 p.

Research output: Contribution to journalReview article

Selective Estrogen Receptor Modulators
Aromatase Inhibitors
Ovulation Induction
Polycystic Ovary Syndrome
Gonadotropins
2012
18 Citations (Scopus)

Reproductive impact of polycystic ovary syndrome

Usadi, R. S. & Legro, R., Dec 1 2012, In : Current Opinion in Endocrinology, Diabetes and Obesity. 19, 6, p. 505-511 7 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Clomiphene
Live Birth
letrozole
Ovulation Induction
2 Citations (Scopus)
Blood Pressure Monitors
Pregnancy Induced Hypertension
Heart Rate
Blood Pressure
Arterial Pressure
2011
22 Citations (Scopus)

Current perspectives of insulin resistance and polycystic ovary syndrome

Pauli, J., Raja-Khan, N., Wu, X. & Legro, R., Dec 1 2011, In : Diabetic Medicine. 28, 12, p. 1445-1454 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin Resistance
Cardiovascular Diseases
Metformin
Life Style
94 Citations (Scopus)

PCOS Forum: Research in polycystic ovary syndrome today and tomorrow

Pasquali, R., Stener-Victorin, E., Yildiz, B. O., Duleba, A. J., Hoeger, K., Mason, H., Homburg, R., Hickey, T., Franks, S., Tapanainen, J. S., Balen, A., Abbott, D. H., Diamanti-Kandarakis, E. & Legro, R. S., Apr 1 2011, In : Clinical Endocrinology. 74, 4, p. 424-433 10 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Research
Androgens
Insulin Resistance
Endocrine Disruptors
12 Citations (Scopus)

Recruitment challenges of a multicenter randomized controlled varicocelectomy trial

Trussell, J. C., Christman, G. M., Ohl, D. A., Legro, R., Krawetz, S. A., Snyder, P. J., Patrizio, P., Polotsky, A. J., Diamond, M. P., Casson, P. R., Coutifaris, C., Barnhart, K., Brzyski, R. G., Schlaff, W. D., Meacham, R., Shin, D., Thomas, T., Zhang, M., Santoro, N., Eisenberg, E. & 1 others, Zhang, H., Jan 1 2011, In : Fertility and sterility. 96, 6, p. 1299-1305 7 p.

Research output: Contribution to journalReview article

Reproductive Medicine
Insemination
Male Infertility
Randomized Controlled Trials
Placebos
42 Citations (Scopus)

The physiological basis of complementary and alternative medicines for polycystic ovary syndrome

Raja-Khan, N., Stener-Victorin, E., Wu, X. & Legro, R. S., Jul 1 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 1, p. E1-E10

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Complementary Therapies
Autonomic Nervous System
Acupuncture
Therapeutics
2009
12 Citations (Scopus)

Insulin resistance in women's health: Why it matters and how to identify it

Legro, R. S., Aug 1 2009, In : Current Opinion in Obstetrics and Gynecology. 21, 4, p. 301-305 5 p.

Research output: Contribution to journalReview article

Women's Health
Insulin Resistance
Phenotype
Gestational Diabetes
Pregnancy Complications
2007
17 Citations (Scopus)

Erectile dysfunction: does insulin resistance play a part?

Trussell, J. C. & Legro, R., Oct 1 2007, In : Fertility and sterility. 88, 4, p. 771-778 8 p.

Research output: Contribution to journalReview article

Erectile Dysfunction
Insulin Resistance
Nitric Oxide
MEDLINE
Type 5 Cyclic Nucleotide Phosphodiesterases
795 Citations (Scopus)

Polycystic ovary syndrome

Norman, R. J., Dewailly, D., Legro, R. & Hickey, T. E., Aug 25 2007, In : Lancet. 370, 9588, p. 685-697 13 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Anovulation
Hyperandrogenism
Hirsutism
Acne Vulgaris
2006
8 Citations (Scopus)

A twenty-first century research agenda for polycystic ovary syndrome

Legro, R., Azziz, R. & Giudice, L., Jun 1 2006, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 20, 2, p. 331-336 6 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Research
Translational Medical Research
Expert Testimony
Natural History
89 Citations (Scopus)

Obesity and the role of gut and adipose hormones in female reproduction

Gosman, G. G., Katcher, H. I. & Legro, R. S., Sep 1 2006, In : Human Reproduction Update. 12, 5, p. 585-601 17 p.

Research output: Contribution to journalReview article

Reproduction
Obesity
Adipokines
Hormones
Weight Loss
71 Citations (Scopus)

The role of genes and environment in the etiology of PCOS

Diamanti-Kandarakis, E., Kandarakis, H. & Legro, R. S., Aug 1 2006, In : Endocrine. 30, 1, p. 19-26 8 p.

Research output: Contribution to journalReview article

Genes
Insulin Receptor
Follistatin
Phenotype
Obesity
2005
4 Citations (Scopus)

Diagnosis and management of polycystic ovary syndrome

Raja-Khan, N. & Legro, R., Apr 2005, In : Journal of Clinical Outcomes Management. 12, 4, p. 218-226 9 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Metformin
Ovulation
Insulin Resistance
Hirsutism
2004
278 Citations (Scopus)

Detecting Insulin Resistance in Polycystic Ovary Syndrome: Purposes and Pitfalls

Legro, R., Castracane, V. D. & Kauffman, R. P., Feb 1 2004, In : Obstetrical and Gynecological Survey. 59, 2, p. 141-154 14 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin Resistance
Glucose Intolerance
Glucose Tolerance Test
Dyslipidemias
34 Citations (Scopus)

Surrogate end-points or primary outcomes in clinical trials in women with polycystic ovary syndrome?

Legro, R. & Myers, E., Jan 1 2004, In : Human Reproduction. 19, 8, p. 1697-1704 8 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Biomarkers
Clinical Trials
Ovulation
Pregnancy
2003
1 Citation (Scopus)

Diabetes prevalence and risk factors in polycystic ovary syndrome

Legro, R., Jan 1 2003, In : Infertility and Reproductive Medicine Clinics of North America. 14, 4, p. 591-601 11 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Glucose Intolerance
Glucose
Fasting
Type 2 Diabetes Mellitus
30 Citations (Scopus)

Diagnostic Criteria in Polycystic Ovary Syndrome

Legro, R. S., Aug 1 2003, In : Seminars in reproductive medicine. 21, 3, p. 267-275 9 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Ovulation
Insulin Resistance
Hyperandrogenism
Signs and Symptoms
360 Citations (Scopus)

Polycystic ovary syndrome and cardiovascular disease: A premature association?

Legro, R. S., Jun 1 2003, In : Endocrine Reviews. 24, 3, p. 302-312 11 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Cardiovascular Diseases
Anovulation
Hyperandrogenism
Ovary
2002
15 Citations (Scopus)

Diabetes prevalence and risk factors in polycystic ovary syndrome

Legro, R., Dec 1 2002, In : Current Opinion in Endocrinology and Diabetes. 9, 6, p. 451-458 8 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Glucose Intolerance
Glucose Tolerance Test
Glucose
Anovulation
1 Citation (Scopus)

Management and treatment of hirsutism in the elderly woman

Legro, R. S., Nov 1 2002, In : Annals of Long-Term Care. 10, 11, p. 41-47 7 p.

Research output: Contribution to journalReview article

Hirsutism
Therapeutics
Skin Cream
Eflornithine
Electrolysis
28 Citations (Scopus)

Polycystic ovary syndrome: Long term sequelae and management

Legro, R., Apr 1 2002, In : Minerva Ginecologica. 54, 2, p. 97-114 18 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Glucose Intolerance
Insulin
Type 2 Diabetes Mellitus
Insulin Resistance
37 Citations (Scopus)

Polycystic ovary syndrome in adolescents.

Kent, S. C. & Legro, R., Jan 1 2002, In : Adolescent medicine (Philadelphia, Pa.). 13, 1

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin
Lipids
Insulin Resistance
Fasting
1996
11 Citations (Scopus)

The role of insulin resistance in polycystic ovary syndrome

Legro, R. S. & Dunaif, A., Jul 1996, In : Endocrinologist. 6, 4, p. 307-321 15 p.

Research output: Contribution to journalReview article

Polycystic Ovary Syndrome
Insulin Resistance
Insulin
Anovulation
Type 2 Diabetes Mellitus