• 513 Citations
  • 11 h-Index
20082019
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Research Output 2008 2019

  • 513 Citations
  • 11 h-Index
  • 10 Article
  • 3 Letter
  • 2 Comment/debate
  • 2 Review article
2019

Sam68 is required for the growth and survival of nonmelanoma skin cancer

Fu, K., Sun, X., Xia, X., Hobbs, R., Guo, Y., Coulombe, P. A. & Wan, F., Jan 1 2019, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journalArticle

Open Access
Skin Neoplasms
Keratinocytes
DNA Damage
Survival
Growth
2018
2 Citations (Scopus)

Antimicrobial action of calprotectin that does not involve metal withholding

Besold, A. N., Culbertson, E. M., Nam, L., Hobbs, R., Boyko, A., Maxwell, C. N., Chazin, W. J., Marques, A. R. & Culotta, V. C., Dec 1 2018, In : Metallomics. 10, 12, p. 1728-1742 15 p.

Research output: Contribution to journalArticle

Leukocyte L1 Antigen Complex
Metals
Pathogens
Escherichia coli
Growth
2017
2 Citations (Scopus)

Act1: A Psoriasis Susceptibility Gene Playing its Part in Keratinocytes

Hobbs, R., Smith, S. H. & Getsios, S., Jul 1 2017, In : Journal of Investigative Dermatology. 137, 7, p. 1410-1412 3 p.

Research output: Contribution to journalComment/debate

Keratinocytes
Psoriasis
Interleukin-17 Receptors
Genes
Transcriptome
2016
17 Citations (Scopus)

Keratins Are Going Nuclear

Hobbs, R., Jacob, J. T. & Coulombe, P. A., Aug 8 2016, In : Developmental Cell. 38, 3, p. 227-233 7 p.

Research output: Contribution to journalComment/debate

Keratin-17
Cytoskeletal Proteins
Cell proliferation
Keratins
Gene expression
14 Citations (Scopus)

Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo

Hobbs, R., Batazzi, A. S., Han, M. C. & Coulombe, P. A., Oct 27 2016, In : Oncogene. 35, 43, p. 5653-5662 10 p.

Research output: Contribution to journalArticle

Keratin-17
Carcinogenesis
Cytokines
Papillomaviridae
Uterine Cervical Neoplasms
3 Citations (Scopus)

Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice

Fu, K., Sun, X., Wier, E. M., Hodgson, A., Hobbs, R. & Wan, F., Dec 20 2016, In : eLife. 5, DECEMBER2016, e21957.

Research output: Contribution to journalArticle

Colon
Epithelium
Chemical activation
DNA Damage
Irradiation
2015
42 Citations (Scopus)

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

Hobbs, R., Depianto, D. J., Jacob, J. T., Han, M. C., Chung, B. M., Batazzi, A. S., Poll, B. G., Guo, Y., Han, J., Ong, S., Zheng, W., Taube, J. M., Ciháková, D., Wan, F. & Coulombe, P. A., Aug 30 2015, In : Nature Genetics. 47, 8, p. 933-938 6 p.

Research output: Contribution to journalArticle

Keratin-17
Regulator Genes
Keratins
Keratinocytes
Gene Expression
2013
18 Citations (Scopus)

Phosphorylation of serine 4642 in the C-terminus of plectin by MNK2 and PKA modulates its interaction with intermediate filaments

Bouameur, J. E., Schneider, Y., Begre, N., Hobbs, R., Lingasamy, P., Fontao, L., Green, K. J., Favre, B. & Borradori, L., Oct 18 2013, In : Journal of Cell Science. 126, 18, p. 4195-4207 13 p.

Research output: Contribution to journalArticle

Plectin
Intermediate Filaments
Serine
Phosphorylation
HeLa Cells

Response to garrod

Hobbs, R., Godsel, L. M. & Green, K. J., Jan 1 2013, In : Journal of Investigative Dermatology. 133, 2, p. 578-579 2 p.

Research output: Contribution to journalLetter

104 Citations (Scopus)

The expanding significance of keratin intermediate filaments in normal and diseased epithelia

Pan, X., Hobbs, R. & Coulombe, P. A., Jan 1 2013, In : Current Opinion in Cell Biology. 25, 1, p. 47-56 10 p.

Research output: Contribution to journalReview article

Intermediate Filaments
Keratins
Epithelium
Premature Aging
Intermediate Filament Proteins
2012
39 Citations (Scopus)

Desmoplakin regulates desmosome hyperadhesion

Hobbs, R. & Green, K. J., Jan 1 2012, In : Journal of Investigative Dermatology. 132, 2, p. 482-485 4 p.

Research output: Contribution to journalLetter

Desmoplakins
11 Citations (Scopus)

Keratin intermediate filament proteins - Novel regulators of inflammation and immunity in skin

Hobbs, R., Lessard, J. C. & Coulombe, P. A., Nov 15 2012, In : Journal of Cell Science. 125, 22, p. 5257-5258 2 p.

Research output: Contribution to journalArticle

Keratin-1
Intermediate Filament Proteins
Interleukin-18
Keratins
Immunity
2011
42 Citations (Scopus)

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling

Hobbs, R., Amargo, E. V., Somasundaram, A., Simpson, C. L., Prakriya, M., Denning, M. F. & Green, K. J., Mar 1 2011, In : FASEB Journal. 25, 3, p. 990-1001 12 p.

Research output: Contribution to journalArticle

Desmoplakins
Reticulum
Calcium-Transporting ATPases
Adhesives
Protein Kinase C
2010
24 Citations (Scopus)

Insights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosa

Hobbs, R., Han, S. Y., Van Der Zwaag, P. A., Bolling, M. C., Jongbloed, J. D. H., Jonkman, M. F., Getsios, S., Paller, A. S. & Green, K. J., Jan 1 2010, In : Journal of Investigative Dermatology. 130, 11, p. 2680-2683 4 p.

Research output: Contribution to journalLetter

Desmoplakins
55 Citations (Scopus)

Plakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA

Godsel, L. M., Dubash, A. D., Bass-Zubek, A. E., Amargo, E. V., Klessner, J. L., Hobbs, R., Chen, X. & Green, K. J., Aug 15 2010, In : Molecular biology of the cell. 21, 16, p. 2844-2859 16 p.

Research output: Contribution to journalArticle

Plakophilins
Actomyosin
Desmosomes
Desmoplakins
Actins
2008
50 Citations (Scopus)

Intermediate filament assembly: dynamics to disease

Godsel, L. M., Hobbs, R. & Green, K. J., Jan 1 2008, In : Trends in Cell Biology. 18, 1, p. 28-37 10 p.

Research output: Contribution to journalReview article

Intermediate Filaments
Intermediate Filament Proteins
Actomyosin
Microtubules
Vertebrates
90 Citations (Scopus)

Plakophilin 2: A critical scaffold for PKCα that regulates intercellular junction assembly

Bass-Zubek, A. E., Hobbs, R., Amargo, E. V., Garcia, N. J., Hsieh, S. N., Chen, X., Wahl, J. K., Denning, M. F. & Green, K. J., May 19 2008, In : Journal of Cell Biology. 181, 4, p. 605-613 9 p.

Research output: Contribution to journalArticle

Plakophilins
Desmoplakins
Intercellular Junctions
Protein Kinase C
Desmosomal Cadherins