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Research Output 1997 2018

  • 705 Citations
  • 13 h-Index
  • 26 Article
  • 3 Review article
2018

Current Knowledge for the Western Blot Normalization

Lee, S., 2018, In : Journal of Medical Oncology and Therapeutics. 3, 1, p. 3-9

Research output: Contribution to journalArticle

4 Citations (Scopus)

Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells

Ramisetti, S. R., Pandey, M. K., Lee, S., Karelia, D., Narayan, S., Amin, S. & Sharma, A., Jan 1 2018, In : European Journal of Medicinal Chemistry. 143, p. 1919-1930 12 p.

Research output: Contribution to journalArticle

Melanoma
Assays
Cells
Derivatives
Cell death

Inhibition of migration and invasion in melanoma cells by β-escin via the ERK/NF-κB signaling pathway

Kwak, H. S., An, H., Alam, M. B., Choi, W. S., Lee, S. & Lee, S. H., Jan 1 2018, In : Biological and Pharmaceutical Bulletin. 41, 10, p. 1606-1610 5 p.

Research output: Contribution to journalArticle

Escin
NF-kappa B
Melanoma
Cell Movement
Aesculus
2017
1 Citation (Scopus)

Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data

Lee, S., Zhu, J., Salzberg, A. C., Zhang, B., Liu, D., Muscat, J., Langan, S. T. & Connor, J., Mar 1 2017, In : PloS one. 12, 3, e0174778.

Research output: Contribution to journalArticle

Atlases
Glioblastoma
Nucleotides
Genes
nucleotides
5 Citations (Scopus)

HFE genotype affects exosome phenotype in cancer

Mrowczynski, O. D., Madhankumar, A. B., Slagle-Webb, B., Lee, S. Y., Zacharia, B. E. & Connor, J. R., Aug 2017, In : Biochimica et Biophysica Acta - General Subjects. 1861, 8, p. 1921-1928 8 p.

Research output: Contribution to journalArticle

Exosomes
Tumors
Genotype
Phenotype
Neoplasms
2016
94 Citations (Scopus)

Temozolomide resistance in glioblastoma multiforme

Lee, S., Sep 1 2016, In : Genes and Diseases. 3, 3, p. 198-210 13 p.

Research output: Contribution to journalReview article

temozolomide
Glioblastoma
Cells
Cell Line
Alkylating Agents
2015
2 Citations (Scopus)

Association studies of HFE C282Y and H63D variants with oral cancer risk and iron homeostasis among whites and blacks

Jones, N. R., Ashmore, J. H., Lee, S. Y., Richie, J. P., Lazarus, P. & Muscat, J. E., Dec 9 2015, In : Cancers. 7, 4, p. 2386-2396 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Homeostasis
Iron
Alleles
Biomarkers
3 Citations (Scopus)

HFE polymorphisms affect survival of brain tumor patients

Lee, S., Slagle-Webb, B., Sheehan, J. M., Zhu, J., Muscat, J., Glantz, M. & Connor, J., Jan 1 2015, In : Journal of neuro-oncology. 122, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Survival
Genotype
Iron
Neuroblastoma
7 Citations (Scopus)

The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line

Mairuae, N., Connor, J., Lee, S., Cheepsunthorn, P. & Tongjaroenbuangam, W., Aug 1 2015, In : Neuroscience letters. 603, p. 6-11 6 p.

Research output: Contribution to journalArticle

Abelmoschus
Neuroblastoma
Alzheimer Disease
Cell Line
Serine
2014
4 Citations (Scopus)

C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells

Ali-Rahmani, F., Huang, M. A., Schengrund, C. L., Connor, J. R. & Lee, S. Y., Feb 12 2014, In : PloS one. 9, 2, e88724.

Research output: Contribution to journalArticle

cholesterol metabolism
Neuroblastoma
Metabolism
Genes
Cholesterol
5 Citations (Scopus)

Characterization of a novel anti-cancer compound for astrocytomas

Lee, S. Y., Slagle-Webb, B., Rizk, E., Patel, A., Miller, P. A., Sung, S. S. & Connor, J. R., Sep 25 2014, In : PloS one. 9, 9, e108166.

Research output: Contribution to journalArticle

temozolomide
Astrocytoma
Tumors
neoplasms
cytotoxicity
21 Citations (Scopus)

H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment

Ali-Rahmani, F., Grigson-Kennedy, P. S., Lee, S., Neely, E., Connor, J. & Schengrund, C-L., Jan 1 2014, In : Neurobiology of Aging. 35, 6, p. 1511.e1-1511.e12

Research output: Contribution to journalArticle

Hemochromatosis
Cholesterol
Mutation
Apolipoprotein E4
Alzheimer Disease
2013
6 Citations (Scopus)
Amyotrophic Lateral Sclerosis
Muscles
Genotype
Muscle Proteins
Superoxide Dismutase-1
2011
7 Citations (Scopus)

Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues

Hall, E. C., Lee, S., Mairuae, N., Simmons, Z. & Connor, J., Aug 1 2011, In : Neurobiology of Aging. 32, 8, p. 1409-1419 11 p.

Research output: Contribution to journalArticle

Serine
Glycogen Synthase Kinase 3
Phosphorylation
Iron
Oxidative Stress
19 Citations (Scopus)

HFE polymorphisms affect cellular glutamate regulation

Mitchell, R. M., Lee, S., Simmons, Z. & Connor, J., Jun 1 2011, In : Neurobiology of Aging. 32, 6, p. 1114-1123 10 p.

Research output: Contribution to journalArticle

Glutamic Acid
Iron
Genotype
Calcium
Cell Line
13 Citations (Scopus)

HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A

Lee, S. Y., Liu, S., Mitchell, R. M., Slagle-Webb, B., Hong, Y. S., Sheehan, J. M. & Connor, J. R., Nov 1 2011, In : International Journal of Cancer. 129, 9, p. 2104-2114 11 p.

Research output: Contribution to journalArticle

Neuroblastoma
temozolomide
Small Interfering RNA
Neoplasms
Cyclin-Dependent Kinase Inhibitor p16
22 Citations (Scopus)

Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression

Zhang, Y., Cheng, Y., Zhang, L., Ren, X., Huber-Keener, K. J., Lee, S., Yun, J., Wang, H. G. & Yang, J. M., Oct 14 2011, In : Biochemical and Biophysical Research Communications. 414, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

Glioma
Phosphotransferases
Down-Regulation
Elongation Factor 2 Kinase
Cells
34 Citations (Scopus)

Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability

Liu, Y., Lee, S., Neely, E., Nandar, W., Moyo, M., Simmons, Z. & Connor, J., Apr 15 2011, In : Journal of Biological Chemistry. 286, 15, p. 13161-13170 10 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Mutant Proteins
Unfolded Protein Response
Iron
Caspase 3
2010
12 Citations (Scopus)
Peptidylprolyl Isomerase
Alleles
Phosphorylation
Iron
Alzheimer Disease
9 Citations (Scopus)

The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure

Mairuae, N., Hall, E. C., Cheepsunthorn, P., Lee, S. & Connor, J., Nov 1 2010, In : Journal of Neuroscience Research. 88, 14, p. 3079-3089 11 p.

Research output: Contribution to journalArticle

Amyloid
Mitochondria
Peptides
Genes
Alzheimer Disease
2009
27 Citations (Scopus)

Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1

Mitchell, R. M., Lee, S., Randazzo, W. T., Simmons, Z. & Connor, J., Feb 19 2009, In : Journal of Neuroinflammation. 6, 6.

Research output: Contribution to journalArticle

Chemokine CCL2
Iron
Minocycline
Cytokines
Genotype
2007
48 Citations (Scopus)

Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE

Lee, S. Y., Patton, S. M., Henderson, R. J. & Connor, J. R., Feb 1 2007, In : FASEB Journal. 21, 2, p. 564-576 13 p.

Research output: Contribution to journalArticle

Hemochromatosis
Iron
Genes
Cells
Cell Line
2006
61 Citations (Scopus)

HFE mutations and Alzheimer's disease

Connor, J. & Lee, S., Jan 1 2006, In : Journal of Alzheimer's Disease. 10, 2-3, p. 267-276 10 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Mutation
Iron
Homeostasis
Hemochromatosis
2005
15 Citations (Scopus)

Regulation of Hfe by stress factors in BV-2 cells

Lee, S. & Connor, J., Jan 1 2005, In : Neurobiology of Aging. 26, 6, p. 803-812 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Mutation
Iron
Vitamin K 3
Transferrin Receptors
2004
92 Citations (Scopus)

Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences

Wang, X. S., Lee, S., Simmons, Z., Boyer, P., Scott, K., Liu, W. & Connor, J., Dec 15 2004, In : Journal of the neurological sciences. 227, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Mutation
Incidence
Neuromuscular Diseases
Oxidative Stress
2003
75 Citations (Scopus)
Thioredoxins
Cyclic GMP
Estrogen Receptors
Estradiol
Oxidative stress
47 Citations (Scopus)

Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen

Chiueh, C. C., Lee, S., Andoh, T. & Murphy, D. L., Jun 1 2003, In : Endocrine. 21, 1, p. 27-31 5 p.

Research output: Contribution to journalReview article

Thioredoxins
Estrogens
Guanosine Monophosphate
Estradiol
Estrogen Receptors
2000
71 Citations (Scopus)

Preconditioning regulation of bcl-2 and p66(shc) by human NOS1 enhances tolerance to oxidative stress

Andoh, T., Lee, S. & Chuang Chin Chiueh, C. C., Nov 29 2000, In : FASEB Journal. 14, 14, p. 2144-2146 3 p.

Research output: Contribution to journalArticle

oxidative stress
1997
1 Citation (Scopus)

44-homooligomycin e, a new cytotoxic macrolide antibiotic from streptomyces ostreogriseus

Kim, H. S., Bang, H. J., Lee, S., Yoo, O. J., Yoo, J. C., Kim, Y. H. & Lee, J. J., Jan 1 1997, In : Bioscience, Biotechnology and Biochemistry. 61, 2, p. 378-380 3 p.

Research output: Contribution to journalArticle

Antineoplastic Antibiotics
Macrolides
Streptomyces
Cytotoxicity
Tumor Cell Line