Sarah Bronson, PhD

Director, Research Development

  • Phone717 531-5194
  • 2578 Citations
  • 24 h-Index
1991 …2017
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Personal profile

Research interests

Dr. Sarah Bronson is known for the creation of targeted transgenic lines, where small recombinant transgenic sequences, as well as bacterial artificial chromosome-based transgenic sequences, are introduced in a single-copy at the X-linked hypoxanthine phosphoribosyl transferase (HPRT) locus by a directly selectable homologous recombination event in murine embryonic stem cells. She has had a long-standing interest in manipulating the mouse genome via genetic alteration of mouse embryonic stem cells to study disease of hematologic, immunologic, developmental and metabolic importance. 

Teaching and educational interests

Dr. Sarah Bronson is a Distinguished Educator of the College of Medicine who has been active in training doctoral students, serving on dissertation committees, directing and developing graduate degree programs, revising and directing curriculum and developing teaching metrics. She also participates in the undergraduate medical curriculum as a small-group facilitator. At the faculty level, Dr. Bronson co-directs the nationally recognized Junior Faculty Development Program at the College of Medicine, a program with a holistic curriculum and mentored project designed to enable sustainable career trajectories in an academic health system. In this capacity and in her co-directorship of the Grants Academy at the College of Medicine, she has had a sustained impact on the careers of more than 200 faculty members at the College of Medicine, and many more in less formal contexts. She is particularly interested in the professional development topics of interdisciplinary research, scholarship, leadership and resilience.

Education/Academic qualification

Postdoctoral Training, University of North Carolina at Chapel Hill

… → Oct 1996

Biology and Biomedical Sciences, PhD, Washington University St. Louis

… → Aug 15 1991

Biology, BA, Saint Olaf College

… → May 19 1986

Fingerprint Dive into the research topics where Sarah Bronson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Embryonic Stem Cells Medicine & Life Sciences
Transgenes Medicine & Life Sciences
Yeast Artificial Chromosomes Medicine & Life Sciences
Diabetic Retinopathy Medicine & Life Sciences
Insulin Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Retina Medicine & Life Sciences
Homologous Recombination Medicine & Life Sciences

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Projects 2001 2006

Osteoblasts
Stem Cells
Embryonic Stem Cells
Rheumatic Diseases
Mesenchymal Stromal Cells

Research Output 1991 2017

  • 2578 Citations
  • 24 h-Index
  • 32 Article
  • 4 Review article
  • 1 Letter
  • 1 Short survey
9 Citations (Scopus)

Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice

You, H., Gao, T., Raup-Konsavage, W. M., Cooper, T. K., Bronson, S. K., Reeves, W. B. & Awad, A. S., Mar 1 2017, In : Kidney International. 91, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

CCR Receptors
Podocytes
Kidney
Diabetic Nephropathies
Wounds and Injuries
8 Citations (Scopus)

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats

Masser, D. R., VanGuilder Starkey, H. D., Bixler, G. V., Dunton, W., Bronson, S. K. & Freeman, W. M., Jan 1 2014, In : Experimental Eye Research. 125, p. 95-106 12 p.

Research output: Contribution to journalArticle

Synapses
Insulin
Therapeutics
Diabetic Retinopathy
Retinal Diseases
29 Citations (Scopus)

Nanoliposomal minocycline for ocular drug delivery

Kaiser, J. M., Imai, H., Haakenson, J. K., Brucklacher, R. M., Fox, T. E., Shanmugavelandy, S. S., Unrath, K. A., Pedersen, M. M., Dai, P., Freeman, W. M., Bronson, S. K., Gardner, T. W. & Kester, M., Jan 1 2013, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 9, 1, p. 130-140 11 p.

Research output: Contribution to journalArticle

Minocycline
Drug delivery
Liposomes
Medical problems
Pharmaceutical Preparations
13 Citations (Scopus)

Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis

Hirschler-Laszkiewicz, I., Zhang, W., Keefer, K., Conrad, K., Tong, Q., Chen, S., Bronson, S., Cheung, J. Y. & Miller, B., Jan 1 2012, In : Experimental Hematology. 40, 1, p. 71-83 13 p.

Research output: Contribution to journalArticle

Hemolysis
Knockout Mice
Oxidative Stress
Erythrocytes
Erythrocyte Indices
17 Citations (Scopus)

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

Bixler, G. V., Vanguilder, H. D., Brucklacher, R. M., Kimball, S. R., Bronson, S. K. & Freeman, W. M., May 17 2011, In : BMC Medical Genomics. 4, 40.

Research output: Contribution to journalArticle

Transcriptome
Insulin
Therapeutics
Genes
Diabetic Retinopathy