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  • 13 Similar Profiles
Epoxy Compounds Medicine & Life Sciences
DNA Adducts Medicine & Life Sciences
Benzo(a)pyrene Medicine & Life Sciences
Carcinogens Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Metabolites Chemical Compounds
DNA Medicine & Life Sciences
Lung Medicine & Life Sciences

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Projects 1979 2019

Targeted Sphingolipid Metabolism for Treatment of AML

Claxton, D., Wang, H., Wang, H., Amin, S., Liao, J. (., Fox, T., Loughran, T. P., Loughran, T. P., Kester, M., Kester, M. & Cabot, M. C.

National Institutes of Health

9/10/138/31/19

Project: Research project

Acute Myeloid Leukemia
Acid Ceramidase
Sphingolipids
Ceramides
Tamoxifen
Carcinogens
Derivatives
Polycyclic Aromatic Hydrocarbons
Metabolites
Purification
Carcinogenesis
Pentanones
Cytochrome P-450 Enzyme System
Lung
Microsomes

SYNTHESIS OF SELECTED CHEMICAL CARCINOGENS

Amin, S., Ruehle, P. & Kaplan, J.

National Institutes of Health

3/16/923/15/97

Project: Research project

Carcinogens
Derivatives
Polycyclic Aromatic Hydrocarbons
Polycyclic aromatic hydrocarbons
Metabolites

CANCER CENTER SUPPORT GRANT

Amin, S., Haley, N. J., Rivenson, A., Ronai, Z., Wynder, E., Brunnemann, K., Ng, S., Rozycki, L., Hard, G., Sweeney, N., Nixon, D., Jeffrey, A., Iatropoulos, M., Thompson, S., Prokopczyk, B., Richie, J. & Albino, A.

National Institutes of Health

8/1/7911/30/06

Project: Research project

Synthetic Chemistry Techniques
Photolysis
Neoplasms
Environmental Carcinogens
Assays

Research Output 1971 2019

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Bioactivity
Stem cells
Fluorouracil
Antineoplastic Agents

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

Frieben, E. E., Amin, S. & Sharma, A., Jan 1 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Sulfur
Isothiocyanates
Neoplasms
Organoselenium Compounds
Glucosinolates

Identification of a novel quinoxaline-isoselenourea targeting the STAT3 pathway as a potential melanoma therapeutic

Alcolea, V., Karelia, D. N., Pandey, M. K., Plano, D., Singh, P., Palop, J. A., Amin, S., Sanmartín, C. & Sharma, A., Feb 1 2019, In : International journal of molecular sciences. 20, 3, 521.

Research output: Contribution to journalArticle

quinoxalines
STAT3 Transcription Factor
Quinoxalines
Transcription
Transducers

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Desai, D., Lauver, M., Ostman, A., Cruz, L., Ferguson, K., Jin, G., Roper, B., Brosius, D., Lukacher, A., Amin, S. & Buchkovich, N., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1795-1803 9 p.

Research output: Contribution to journalArticle

Qa-SNARE Proteins
Viruses
Antiviral Agents
Polyomavirus
Stem Cell Transplantation
1 Citation (Scopus)

Leishmanicidal activity of isoselenocyanate derivatives

Fernández-Rubio, C., Larrea, E., Guerrero, J. P., Herrero, E. S., Gamboa, I., Berrio, C., Plano, D., Amin, S., Sharma, A. & Nguewa, P. A., Feb 1 2019, In : Antimicrobial Agents and Chemotherapy. 63, 2, e00904-18.

Research output: Contribution to journalArticle

Leishmania major
Leishmaniasis
Leishmania
Amphotericin B
Cell Cycle