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Sinisa Dovat, PhD, MD

    • 990 Citations
    • 19 h-Index
    1991 …2022
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    • 5 Similar Profiles
    Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
    Leukemia Medicine & Life Sciences
    Casein Kinase II Medicine & Life Sciences
    Ikaros Transcription Factor Medicine & Life Sciences
    Genes Chemical Compounds
    Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
    B-Lymphocytes Medicine & Life Sciences
    Neoplasms Medicine & Life Sciences

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    Projects 1999 2022

    Targeting CK2 oncogenic pathway to overcome drug resistance in high-risk leukemia

    Dovat, S.

    National Institutes of Health

    6/15/17 → 5/31/22

    Project: Research project

    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Drug Resistance
    Leukemia
    B-Lymphocytes
    Folic Acid

    Targeting CRLF2 and Ikaros Alterations to Reduce Health Disparities in Childhood Leukemia

    Dovat, S. & Payne, K.

    National Institutes of Health

    7/1/16 → 6/30/21

    Project: Research project

    B-Lymphoid Precursor Cells
    Leukemia
    Hispanic Americans
    Health
    Heterografts

    The Role of Zinc Finger Genes in Leukemogenesis

    Dovat, S.

    National Institutes of Health

    7/1/09 → 6/30/15

    Project: Research project

    Zinc Fingers
    Phosphorylation
    Leukemia
    Chromatin Assembly and Disassembly
    Genes

    The Role of Zinc Finger Genes in Cellular Proliferation

    Dovat, S.

    National Institutes of Health

    8/12/05 → 7/31/08

    Project: Research project

    Zinc Fingers
    B-Lymphocytes
    Cell Proliferation
    Ikaros Transcription Factor
    Phosphorylation

    THE ROLE OF ZINC FINGER GENES IN HEMATOPOIESIS

    Dovat, S.

    National Institutes of Health

    9/1/99 → 8/31/04

    Project: Research project

    Zinc Fingers
    Hematopoiesis
    T-Lymphocytes
    Cell Cycle
    B-Lymphocytes

    Research Output 1991 2019

    HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

    Luo, H., Sobh, A., Vulpe, C. D., Brewer, E., Dovat, S., Qiu, Y. & Huang, S., Mar 31 2019, In : Journal of visualized experiments : JoVE. 145

    Research output: Contribution to journal › Article

    Clustered Regularly Interspaced Short Palindromic Repeats
    Chromatin
    Screening
    Genes
    Gene Expression

    Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

    Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Jan 1 2019, In : Leukemia.

    Research output: Contribution to journal › Article

    Open Access
    Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
    T-Lymphocytes
    Epigenomics
    Chromatin
    Cell Differentiation

    PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells

    Nicolae, C., O’Connor, M. J., Schleicher, E. M., Song, C., Gowda, R., Robertson, G., Dovat, S. & Moldovan, G-L., Jan 1 2019, In : Oncogene.

    Research output: Contribution to journal › Article

    Myeloid Leukemia
    Leukemia
    DNA Damage
    Myeloid Cells
    Differentiation Antigens
    1 Citation (Scopus)

    Aberrant ARID5B expression and its association with Ikaros dysfunction in acute lymphoblastic leukemia

    Ge, Z., Han, Q., Gu, Y., Ge, Q., Ma, J., Sloane, J., Gao, G., Payne, K. J., Szekely, L., Song, C. & Dovat, S., Nov 1 2018, In : Oncogenesis. 7, 11, 84.

    Research output: Contribution to journal › Article

    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Fingers
    Proteins
    Protein Domains
    Cell Proliferation
    1 Citation (Scopus)

    New rapid method to detect BCR-ABL fusion genes with multiplex RT-qPCR in one-tube at a time

    Tong, Y. Q., Zhao, Z. J., Liu, B., Bao, A. Y., Zheng, H. Y., Gu, J., Xia, Y., McGrath, M., Dovat, S., Song, C. & Li, Y., Jun 1 2018, In : Leukemia Research. 69, p. 47-53 7 p.

    Research output: Contribution to journal › Article

    Gene Fusion
    Reverse Transcription
    Real-Time Polymerase Chain Reaction
    Leukemia
    Bone Marrow