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Sinisa Dovat, PhD, MD

    • 1083 Citations
    • 20 h-Index
    1991 …2022
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    • 6 Similar Profiles
    Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
    Leukemia Medicine & Life Sciences
    Casein Kinase II Medicine & Life Sciences
    Ikaros Transcription Factor Medicine & Life Sciences
    B-Lymphocytes Medicine & Life Sciences
    Genes Chemical Compounds
    Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
    Neoplasms Medicine & Life Sciences

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    Projects 1999 2022

    Targeting CK2 oncogenic pathway to overcome drug resistance in high-risk leukemia

    Dovat, S.

    National Institutes of Health

    6/15/17 → 5/31/22

    Project: Research project

    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Drug Resistance
    Leukemia
    B-Lymphocytes
    Folic Acid

    Targeting CRLF2 and Ikaros Alterations to Reduce Health Disparities in Childhood Leukemia

    Dovat, S. & Payne, K.

    National Institutes of Health

    7/1/16 → 6/30/21

    Project: Research project

    B-Lymphoid Precursor Cells
    Leukemia
    Hispanic Americans
    Health
    Heterografts

    The Role of Zinc Finger Genes in Leukemogenesis

    Dovat, S.

    National Institutes of Health

    7/1/09 → 6/30/15

    Project: Research project

    Zinc Fingers
    Phosphorylation
    Leukemia
    Chromatin Assembly and Disassembly
    Genes

    The Role of Zinc Finger Genes in Cellular Proliferation

    Dovat, S.

    National Institutes of Health

    8/12/05 → 7/31/08

    Project: Research project

    Zinc Fingers
    B-Lymphocytes
    Cell Proliferation
    Ikaros Transcription Factor
    Phosphorylation

    THE ROLE OF ZINC FINGER GENES IN HEMATOPOIESIS

    Dovat, S.

    National Institutes of Health

    9/1/99 → 8/31/04

    Project: Research project

    Zinc Fingers
    Hematopoiesis
    T-Lymphocytes
    Cell Cycle
    B-Lymphocytes

    Research Output 1991 2019

    Cellular signaling and epigenetic regulation of gene expression in leukemia

    Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 1 2019, (Accepted/In press) In : Advances in Biological Regulation. 100665.

    Research output: Contribution to journal › Review article

    Open Access
    Gene Expression Regulation
    Epigenomics
    Leukemia
    Ikaros Transcription Factor
    Gene Expression
    1 Citation (Scopus)

    HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

    Luo, H., Sobh, A., Vulpe, C. D., Brewer, E., Dovat, S., Qiu, Y. & Huang, S., Mar 31 2019, In : Journal of visualized experiments : JoVE. 145

    Research output: Contribution to journal › Article

    Clustered Regularly Interspaced Short Palindromic Repeats
    Chromatin
    Screening
    Genes
    Gene Expression
    1 Citation (Scopus)

    Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

    Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Nov 1 2019, In : Leukemia. 33, 11, p. 2720-2731 12 p.

    Research output: Contribution to journal › Article

    Open Access
    Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
    T-Lymphocytes
    Epigenomics
    Chromatin
    Cell Differentiation

    PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells

    Nicolae, C., O’Connor, M. J., Schleicher, E. M., Song, C., Gowda, R., Robertson, G., Dovat, S. & Moldovan, G-L., Jul 4 2019, In : Oncogene. 38, 27, p. 5530-5540 11 p.

    Research output: Contribution to journal › Article

    Myeloid Leukemia
    Leukemia
    DNA Damage
    Myeloid Cells
    Differentiation Antigens
    1 Citation (Scopus)

    RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia

    Han, Q., Ma, J., Gu, Y., Song, H., Kapadia, M., Kawasawa, Y. I., Dovat, S., Song, C. & Ge, Z., Jan 1 2019, In : Journal of Cancer. 10, 16, p. 3842-3850 9 p.

    Research output: Contribution to journal › Article

    Open Access
    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    B-Lymphocytes
    Genetic Recombination
    Clonal Evolution
    Carcinogenesis