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  • 13 Similar Profiles
Nucleosomes Medicine & Life Sciences
Histones Medicine & Life Sciences
Histone Acetyltransferases Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Yeasts Medicine & Life Sciences
Acetylation Medicine & Life Sciences
DNA Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 2000 2023

Structural studies of chromatin complexes

Tan, S.

National Institutes of Health

9/1/188/31/23

Project: Research projectOutstanding Investigator Award

Histone Code
Chromatin
Nucleosomes
Enzymes
Cryoelectron Microscopy
Nucleosomes
Ubiquitination
Histones
Ubiquitin
Enzymes
Nucleosomes
Guanosine
Chromatin
Chromosomes
Eukaryotic Cells

STRUCTURE AND FUNCTION OF GENE REGULATORY COMPLEXES

Tan, S.

National Institutes of Health

3/1/001/31/12

Project: Research projectResearch Project

Regulator Genes
Histone Acetyltransferases
TATA-Box Binding Protein
Histones
Nucleosomes

Research Output 1988 2018

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2

Sun, J., Paduch, M., Kim, S. A., Kramer, R. M., Barrios, A. F., Lu, V., Luke, J., Usatyuk, S., Kossiakoff, A. A. & Tan, S., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10010-10015 6 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Histones
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Acetyl Coenzyme A

The pPSU Plasmids for Generating DNA Molecular Weight Markers

Henrici, R. C., Pecen, T. J., Johnston, J. L. & Tan, S., Dec 1 2017, In : Scientific Reports. 7, 1, 2438.

Research output: Contribution to journalArticle

Plasmids
Molecular Weight
DNA
Molecular Biology
Gels
7 Citations

Differentially Isotope-Labeled Nucleosomes To Study Asymmetric Histone Modification Crosstalk by Time-Resolved NMR Spectroscopy

Liokatis, S., Klingberg, R., Tan, S. & Schwarzer, D., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 29, p. 8262-8265 4 p.

Research output: Contribution to journalArticle

Nucleosomes
Crosstalk
Isotopes
Histones
Nuclear magnetic resonance spectroscopy

Elimination of truncated recombinant protein expressed in Escherichia coli by removing cryptic translation initiation site

Jennings, M. J., Barrios, A. F. & Tan, S., May 1 2016, In : Protein Expression and Purification. 121, p. 17-21 5 p.

Research output: Contribution to journalArticle

Recombinant Proteins
Codon
Escherichia coli
Fungal Proteins
Observation
8 Citations

Multivalent interactions by the set8 histone methyltransferase with its nucleosome substrate

Girish, T. S., McGinty, R. K. & Tan, S., Apr 24 2016, In : Journal of Molecular Biology. 428, 8, p. 1531-1543 13 p.

Research output: Contribution to journalArticle

Nucleosomes
Proliferating Cell Nuclear Antigen
Structural Models
Eukaryotic Cells
Catalysis