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Research Output 1988 2018

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Article
2018
2 Citations (Scopus)

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2

Sun, J., Paduch, M., Kim, S. A., Kramer, R. M., Barrios, A. F., Lu, V., Luke, J., Usatyuk, S., Kossiakoff, A. A. & Tan, S., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10010-10015 6 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Histones
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Acetyl Coenzyme A
2017
1 Citation (Scopus)

The pPSU Plasmids for Generating DNA Molecular Weight Markers

Henrici, R. C., Pecen, T. J., Johnston, J. L. & Tan, S., Dec 1 2017, In : Scientific reports. 7, 1, 2438.

Research output: Contribution to journalArticle

Plasmids
Molecular Weight
DNA
Molecular Biology
Gels
2016
10 Citations (Scopus)

Differentially Isotope-Labeled Nucleosomes To Study Asymmetric Histone Modification Crosstalk by Time-Resolved NMR Spectroscopy

Liokatis, S., Klingberg, R., Tan, S. & Schwarzer, D., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 29, p. 8262-8265 4 p.

Research output: Contribution to journalArticle

Nucleosomes
Crosstalk
Isotopes
Histones
Nuclear magnetic resonance spectroscopy

Elimination of truncated recombinant protein expressed in Escherichia coli by removing cryptic translation initiation site

Jennings, M. J., Barrios, A. F. & Tan, S., May 1 2016, In : Protein Expression and Purification. 121, p. 17-21 5 p.

Research output: Contribution to journalArticle

Recombinant Proteins
Codon
Escherichia coli
Fungal Proteins
Observation
11 Citations (Scopus)

Multivalent interactions by the set8 histone methyltransferase with its nucleosome substrate

Girish, T. S., McGinty, R. K. & Tan, S., Apr 24 2016, In : Journal of Molecular Biology. 428, 8, p. 1531-1543 13 p.

Research output: Contribution to journalArticle

Nucleosomes
Proliferating Cell Nuclear Antigen
Structural Models
Eukaryotic Cells
Catalysis
2015
20 Citations (Scopus)

Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex

Kim, S. A., Chatterjee, N., Jennings, M. J., Bartholomew, B. & Tan, S., Apr 11 2015, In : Nucleic acids research. 43, 10, p. 4868-4880 13 p.

Research output: Contribution to journalArticle

Histone Demethylases
Nucleosomes
DNA
Lysine
Co-Repressor Proteins
4 Citations (Scopus)

Site specificity analysis of Piccolo NuA4-mediated acetylation for different histone complexes

Kuo, Y. M., Henry, R. A., Tan, S., Côté, J. & Andrews, A. J., Dec 1 2015, In : Biochemical Journal. 472, 2, p. 239-248 10 p.

Research output: Contribution to journalArticle

Acetylation
Nucleosomes
Histones
Lysine
Substrates
2014
131 Citations (Scopus)

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

McGinty, R. K., Henrici, R. C. & Tan, S., Oct 30 2014, In : Nature. 514, 7524, p. 591-596 6 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Nucleosomes
Ubiquitination
Ubiquitin-Protein Ligases
Enzymes
2013
39 Citations (Scopus)

ASH2L regulates ubiquitylation signaling to MLL: Trans-Regulation of H3 K4 methylation in higher eukaryotes

Wu, L., Lee, S. Y., Zhou, B., Nguyen, U. T. T., Muir, T. W., Tan, S. & Dou, Y., Mar 28 2013, In : Molecular cell. 49, 6, p. 1108-1120 13 p.

Research output: Contribution to journalArticle

Ubiquitination
Eukaryota
Methylation
Ubiquitin
Histones
67 Citations (Scopus)

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

Lalonde, M. E., Avvakumov, N., Glass, K. C., Joncas, F. H., Saksouk, N., Holliday, M., Paquet, E., Yan, K., Tong, Q., Klein, B. J., Tan, S., Yang, X. J., Kutateladze, T. G. & Côté, J., Sep 1 2013, In : Genes and Development. 27, 18, p. 2009-2024 16 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Histones
Chromatin
Catalytic Domain
Proteins
15 Citations (Scopus)
Nucleosomes
Acetylation
Histones
Histone Acetyltransferases
DNA
6 Citations (Scopus)

Strategies for crystallizing a chromatin protein in complex with the nucleosome core particle

Makde, R. D. & Tan, S., Sep 26 2013, In : Analytical Biochemistry. 442, 2, p. 138-145 8 p.

Research output: Contribution to journalArticle

Nucleosomes
Chromatin
Crystals
Proteins
Diffraction
2011
60 Citations (Scopus)

Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms

Chatterjee, N., Sinha, D., Lemma-Dechassa, M., Tan, S., Shogren-Knaak, M. A. & Bartholomew, B., Oct 1 2011, In : Nucleic acids research. 39, 19, p. 8378-8391 14 p.

Research output: Contribution to journalArticle

Acetylation
Histones
Sucrose
Chromatin
Adenosine Triphosphate
13 Citations (Scopus)

Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress

Charles, G. M., Chen, C., Shih, S. C., Collins, S. R., Beltrao, P., Zhang, X., Sharma, T., Tan, S., Burlingame, A. L., Krogan, N. J., Madhani, H. D. & Narlikar, G. J., Jun 28 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 26, p. 10620-10625 6 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Acetylation
Post Translational Protein Processing
DNA Damage
Chromatin
51 Citations (Scopus)

Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes

Chittuluru, J. R., Chaban, Y., Monnet-Saksouk, J., Carrozza, M. J., Sapountzi, V., Selleck, W., Huang, J., Utley, R. T., Cramet, M., Allard, S., Cai, G., Workman, J. L., Fried, M. G., Tan, S., Côté, J. & Asturias, F. J., Nov 1 2011, In : Nature Structural and Molecular Biology. 18, 11, p. 1196-1203 8 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Nucleosomes
Yeasts
Histones
Acetylation
2010
136 Citations (Scopus)

DNA methylation increases nucleosome compaction and rigidity

Choy, J. S., Wei, S., Lee, J. Y., Tan, S., Chu, S. & Lee, T., Mar 1 2010, In : Journal of the American Chemical Society. 132, 6, p. 1782-1783 2 p.

Research output: Contribution to journalArticle

Nucleosomes
DNA Methylation
Rigidity
Compaction
Rigid structures
28 Citations (Scopus)

RCC1 Uses a Conformationally Diverse Loop Region to Interact with the Nucleosome: A Model for the RCC1-Nucleosome Complex

England, J. R., Huang, J., Jennings, M. J., Makde, R. D. & Tan, S., May 1 2010, In : Journal of Molecular Biology. 398, 4, p. 518-529 12 p.

Research output: Contribution to journalArticle

ran GTP-Binding Protein
Nucleosomes
Chromosomes, Human, Pair 1
Chromatin
Protein Binding
227 Citations (Scopus)

Structure of RCC1 chromatin factor bound to the nucleosome core particle

Makde, R. D., England, J. R., Yennawar, H. P. & Tan, S., Sep 30 2010, In : Nature. 467, 7315, p. 562-566 5 p.

Research output: Contribution to journalArticle

Nucleosomes
Chromatin
Base Pairing
Chromosomes
Monomeric GTP-Binding Proteins
2009
14 Citations (Scopus)

Set2-dependent K36 methylation is regulated by novel intratail interactions within H3

Psathas, J. N., Zheng, S., Tan, S. & Reese, J. C., Dec 1 2009, In : Molecular and cellular biology. 29, 24, p. 6413-6426 14 p.

Research output: Contribution to journalArticle

Methylation
Chromatin Assembly and Disassembly
Post Translational Protein Processing
Glutamine
Histones
2007
85 Citations (Scopus)

Catalytic mechanism of a MYST family histone acetyltransferase

Berndsen, C. E., Albaugh, B. N., Tan, S. & Denu, J. M., Jan 23 2007, In : Biochemistry. 46, 3, p. 623-629 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Acetylcysteine
Cysteine
Enzymes
Acetylation
16 Citations (Scopus)

Expression and purification of recombinant yeast Ada2/Ada3/Gcn5 and Piccolo NuA4 histone acetyltransferase complexes

Barrios, A., Selleck, W., Hnatkovich, B., Kramer, R., Sermwittayawong, D. & Tan, S., Mar 1 2007, In : Methods. 41, 3, p. 271-277 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Nucleosomes
Yeast
Purification
Histones
125 Citations (Scopus)

Interplay of Chromatin Modifiers on a Short Basic Patch of Histone H4 Tail Defines the Boundary of Telomeric Heterochromatin

Altaf, M., Utley, R. T., Lacoste, N., Tan, S., Briggs, S. D. & Côté, J., Dec 28 2007, In : Molecular cell. 28, 6, p. 1002-1014 13 p.

Research output: Contribution to journalArticle

Heterochromatin
Histones
Lysine
Chromatin
Methylation
29 Citations (Scopus)

Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex

Berndsen, C. E., Selleck, W., McBryant, S. J., Hansen, J. C., Tan, S. & Denu, J. M., Feb 27 2007, In : Biochemistry. 46, 8, p. 2091-2099 9 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Nucleosomes
Histones
Acetylation
Substrates
2006
432 Citations (Scopus)

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation

Doyon, Y., Cayrou, C., Ullah, M., Landry, A. J., Côté, V., Selleck, W., Lane, W. S., Tan, S., Yang, X. J. & Côté, J., Jan 6 2006, In : Molecular cell. 21, 1, p. 51-64 14 p.

Research output: Contribution to journalArticle

Tumor Suppressor Proteins
Acetylation
S Phase
Chromatin
Genome
45 Citations (Scopus)

SAGA binds TBP via its Spt8 subunit in competition with DNA: Implications for TBP recruitment

Sermwittayawong, D. & Tan, S., Aug 23 2006, In : EMBO Journal. 25, 16, p. 3791-3800 10 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
Acetyltransferases
DNA
TATA Box
Transcription
2005
281 Citations (Scopus)

Comparison of affinity tags for protein purification

Lichty, J. J., Malecki, J. L., Agnew, H. D., Michelson-Horowitz, D. J. & Tan, S., Jan 1 2005, In : Protein Expression and Purification. 41, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

Drosophila
Trp-Ser- His-Pro-Gln-Phe-Glu-Lys
Yeasts
Escherichia coli Proteins
Protein C
111 Citations (Scopus)

Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1

Li, D., Yea, S., Li, S., Chen, Z., Narla, G., Banck, M., Laborda, J., Tan, S., Friedman, J. M., Friedman, S. L. & Walsh, M. J., Jul 22 2005, In : Journal of Biological Chemistry. 280, 29, p. 26941-26952 12 p.

Research output: Contribution to journalArticle

Adipogenesis
Genes
Adipocytes
Gene encoding
Small Interfering RNA
88 Citations (Scopus)

The pST44 polycistronic expression system for producing protein complexes in Escherichia coli

Tan, S., Kern, R. C. & Selleck, W., Jan 1 2005, In : Protein Expression and Purification. 40, 2, p. 385-395 11 p.

Research output: Contribution to journalArticle

Plasmids
Escherichia coli
Proteins
Biological Phenomena
Histone Acetyltransferases
58 Citations (Scopus)

The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the enhancer of polycomb A domain and chromodomain to acetylate nucleosomes

Selleck, W., Fortin, I., Sermwittayawong, D., Côté, J. & Tan, S., Jul 1 2005, In : Molecular and cellular biology. 25, 13, p. 5535-5542 8 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Nucleosomes
Saccharomyces cerevisiae
Histones
Chromatin
2004
364 Citations (Scopus)

Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans

Doyon, Y., Selleck, W., Lane, W. S., Tan, S. & Côté, J., Mar 1 2004, In : Molecular and cellular biology. 24, 5, p. 1884-1896 13 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Yeasts
Eukaryota
Proteins
cdc Genes
2003
50 Citations (Scopus)

Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes

Bleichenbacher, M., Tan, S. & Richmond, T. J., Sep 26 2003, In : Journal of Molecular Biology. 332, 4, p. 783-793 11 p.

Research output: Contribution to journalArticle

Transcription Factor TFIIA
TATA-Box Binding Protein
Yeasts
DNA
TATA-Binding Protein Associated Factors
150 Citations (Scopus)

Yeast Enhancer of Polycomb defines global Esa1-dependent acetylation of chromatin

Boudreault, A. A., Cronier, D., Selleck, W., Lacoste, N., Utley, R. T., Allard, S., Savard, J., Lane, W. S., Tan, S. & Côté, J., Jun 1 2003, In : Genes and Development. 17, 11, p. 1415-1428 14 p.

Research output: Contribution to journalArticle

Acetylation
Histones
Chromatin
Yeasts
Ephrin-A1
2002
155 Citations (Scopus)

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes

Boyer, L. A., Langer, M. R., Crowley, K. A., Tan, S., Denu, J. M. & Peterson, C. L., Oct 1 2002, In : Molecular cell. 10, 4, p. 935-942 8 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Histones
Histone Acetyltransferases
Enzymes
Catalysis
144 Citations (Scopus)

Role of the Ada2 and Ada3 transcriptional coactivators in histone acetylation

Balasubramanian, R., Pray-Grant, M. G., Selleck, W., Grant, P. A. & Tan, S., Mar 8 2002, In : Journal of Biological Chemistry. 277, 10, p. 7989-7995 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Acetylation
Histones
Yeast
Lysine
2001
58 Citations (Scopus)

A histone fold TAF octamer within the yeast TFIID transcriptional coactivator

Selleck, W., Howley, R., Fang, Q., Podolny, V., Fried, M. G., Buratowski, S. & Tan, S., Aug 29 2001, In : Nature Structural Biology. 8, 8, p. 695-700 6 p.

Research output: Contribution to journalArticle

TATA-Binding Protein Associated Factors
Transcription Factor TFIID
Histones
Yeast
Yeasts
159 Citations (Scopus)

A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli

Tan, S., Jan 1 2001, In : Protein Expression and Purification. 21, 1, p. 224-234 11 p.

Research output: Contribution to journalArticle

Escherichia coli
Ion Exchange Chromatography
Proteins
Plasmids
Peptides
252 Citations (Scopus)

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

Brown, C. E., Howe, L., Sousa, K., Alley, S. C., Carrozza, M. J., Tan, S. & Workman, J. L., Jun 22 2001, In : Science. 292, 5525, p. 2333-2337 5 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Acetyltransferases
Acetylation
Affinity Chromatography
Histones
2000
26 Citations (Scopus)

Crystallization of the yeast MATα2/MCM1/DNA ternary complex: General methods and principles for protein/DNA cocrystallization

Tan, S., Hunziker, Y., Pellegrini, L. & Richmond, T. J., Apr 7 2000, In : Journal of Molecular Biology. 297, 4, p. 947-959 13 p.

Research output: Contribution to journalArticle

Crystallization
Yeasts
DNA
Proteins
DNA-Binding Proteins
67 Citations (Scopus)

Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 Å resolution

Gaiser, F., Tan, S. & Richmond, T. J., Oct 6 2000, In : Journal of Molecular Biology. 302, 5, p. 1119-1127 9 p.

Research output: Contribution to journalArticle

Dimerization
Transcription Factors
Transcription Factor TFIIB
General Transcription Factors
RNA Polymerase II
1998
184 Citations (Scopus)

Crystal structure of the yeast MATα2/MCM1/DNA ternary complex

Tan, S. & Richmond, T. J., Feb 12 1998, In : Nature. 391, 6668, p. 660-666 7 p.

Research output: Contribution to journalArticle

Yeasts
Minichromosome Maintenance 1 Protein
DNA
Repressor Proteins
Homeodomain Proteins
38 Citations (Scopus)

Eukaryotic transcription factors

Tan, S. & Richmond, T. J., Jan 1 1998, In : Current Opinion in Structural Biology. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Transcription Factors
DNA
Archaeal DNA
Transcription Factor TFIIA
Transcription Factor TFIIB
1996
240 Citations (Scopus)

Crystal structure of a yeast TFIIA/TBP/DNA complex

Tan, S., Hunziker, Y., Sargent, D. F. & Richmond, T. J., May 9 1996, In : Nature. 381, 6578, p. 127-134 8 p.

Research output: Contribution to journalArticle

TATA-Box Binding Protein
Transcription Factors
Yeasts
DNA
TATA Box
139 Citations (Scopus)

Mapping nucleosome position at single base-pair resolution by using site-directed hydroxyl radicals

Flaus, A., Luger, K., Tan, S. & Richmond, T. J., Feb 20 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 4, p. 1370-1375 6 p.

Research output: Contribution to journalArticle

Nucleosomes
Base Pairing
Hydroxyl Radical
Histones
DNA
1995
277 Citations (Scopus)

Structure of serum response factor core bound to DNA

Pellegrini, L., Tan, S. & Richmond, T. J., Aug 10 1995, In : Nature. 376, 6540, p. 490-498 9 p.

Research output: Contribution to journalArticle

Serum Response Factor
DNA
MADS Domain Proteins
Serum Response Element
Dimerization
1993
28 Citations (Scopus)

Genomic footprinting of the promoter regions of STE2 and STE3 genes in the yeast Saccharomyces cerevisiae

Ganter, B., Tan, S. & Richmond, T. J., Dec 20 1993, In : Journal of Molecular Biology. 234, 4, p. 975-987 13 p.

Research output: Contribution to journalArticle

Genetic Promoter Regions
Saccharomyces cerevisiae
Nucleosomes
Yeasts
TATA Box
1990
73 Citations (Scopus)

DNA binding-induced conformational change of the yeast transcriptional activator PRTF

Tan, S. & Richmond, T. J., Jul 27 1990, In : Cell. 62, 2, p. 367-377 11 p.

Research output: Contribution to journalArticle

Pheromone Receptors
Yeast
Transcription Factors
Genes
Yeasts
1988
27 Citations (Scopus)

Interactions of purified transcription factors: binding of yeast MAT alpha 1 and PRTF to cell type-specific, upstream activating sequences.

Tan, S., Ammerer, G. & Richmond, T. J., Jan 1 1988, In : The EMBO journal. 7, 13, p. 4255-4264 10 p.

Research output: Contribution to journalArticle

Pheromone Receptors
Yeast
Transcription Factors
Yeasts
Proteins