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Fingerprint Dive into the research topics where Suming Huang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Chromatin Medicine & Life Sciences
Globins Medicine & Life Sciences
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
Genes Medicine & Life Sciences
Acetylation Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Transcription Chemical Compounds
Epigenomics Medicine & Life Sciences

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Projects 2008 2022

Role of lincRNAs in HSC function and leukemogenesis

Huang, S. & Mingjiang, X.

National Institutes of Health

1/15/1912/31/22

Project: Research project

Long Noncoding RNA
Hematopoietic Stem Cells
Chromatin
Genes
Epigenomics
T-Cell Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Oncogenes
Hematopoiesis
Leukemia
Long Noncoding RNA
Hematopoiesis
Hematopoietic Stem Cells
Homeobox Genes
Genes
Long Noncoding RNA
Hematopoiesis
Chromatin
Hematopoietic Stem Cells
Genes
Globins
Gene Expression
Genes
Locus Control Region
Anemia

Research Output 1998 2019

1 Citation (Scopus)

Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia

Yan, B., Chen, Q., Shimada, K., Tang, M., Li, H., Gurumurthy, A., Khoury, J. D., Xu, B., Huang, S. & Qiu, Y., Apr 1 2019, In : Leukemia. 33, 4, p. 931-944 14 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Acute Myeloid Leukemia
Phenotype
Leukemia
Cytarabine

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Luo, H., Sobh, A., Vulpe, C. D., Brewer, E., Dovat, S., Qiu, Y. & Huang, S., Mar 31 2019, In : Journal of visualized experiments : JoVE. 145

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Chromatin
Screening
Genes
Gene Expression

Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
T-Lymphocytes
Epigenomics
Chromatin
Cell Differentiation
2 Citations (Scopus)

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Luo, H., Wang, F., Zha, J., Li, H., Yan, B., Du, Q., Yang, F., Sobh, A., Vulpe, C., Drusbosky, L., Cogle, C., Chepelev, I., Xu, B., Nimer, S. D., Licht, J., Qiu, Y., Chen, B., Xu, M. & Huang, S., Aug 23 2018, In : Blood. 132, 8, p. 837-848 12 p.

Research output: Contribution to journalArticle

Transcription
Acute Myeloid Leukemia
Gene expression
Chromatin
Genes

Erratum: Identification of a novel enhancer/ chromatin opening element associated with high-level γ-globin gene expression (Molecular and Cellular Biology (2018) 38:19 (e00197-18) DOI: 10.1128/MCB.00197-18)

Shen, Y., Bassett, M. A., Gurumurthy, A., Nar, R., Knudson, I. J., Guy, C. R., Perez, A., Mellen, R. W., Ikeda, M., Hossain, M. A., Huang, S., Igarashi, K. & Bungert, J., Oct 1 2018, In : Molecular and cellular biology. 39, 11, e0016819.

Research output: Contribution to journalComment/debate

Open Access
Globins
Chromatin
Cell Biology
Molecular Biology
Gene Expression